Clinical trials: Alcohol-induced Disorders
Alcohol Use Disorder, Heavy Drinking
Online Insomnia Intervention to Reduce Alcohol Use
Alcohol use disorder (AUD) inflicts enormous physical, emotional, and financial burdens on the individual and society at large. Insomnia is highly prevalent among individuals with AUD, and disrupted sleep contributes…
- Trial name
- NCT05630118
- Testing
- SHUTi Intervention, Web-Based Insomnia Education Program
- Where
- United States
- Volunteers
- 113 people, healthy volunteers welcome
- Sponsor
- Jessica Weafer
Alcoholism
The Effects of Levetiracetam on Alcohol Dependent Subjects
This study will attempt to examine whether Levetiracetam (Keppra (TM)) can help people with alcohol dependence cut down on their alcohol consumption.
- Trial name
- NCT00325182
- Testing
- Levetiracetam, Historical controls
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Boston University
Alcohol Drinking, Binge Drinking
Alerta Alcohol. Web-based Computer-tailored Intervention for Binge-drinking Prevention in Spanish Adolescents
This study consists in the the design, implementation, and evaluation of the first web-based computer tailored intervention program aimed at the prevention of binge drinking in Spanish adolescents (Alerta Alcohol).
- Conditions
- Alcohol Drinking, Binge Drinking, Adolescent Behavior
- Trial name
- NCT03288896
- Testing
- Alerta Alcohol
- Where
- Spain
- Volunteers
- 1,230 people, healthy volunteers welcome
- Sponsor
- University of Seville
Alcohol Use Disorder, Mild, Alcohol Use, Unspecified
My Choices: Efficacy and Implementation Study
The aim of the study is to assess the efficacy of the My Choices - Alcohol program by comparing alcohol-use of people before and after doing the program to people that did not do the program on the same period of time (3 months).
- Trial name
- NCT05358613
- Testing
- My Choices
- Where
- 5 sites in Canada
- Volunteers
- 167 people
- Sponsor
- Université du Québec à Trois-Rivières
Alcohol Use Disorder
Guanfacine for Alcohol Use Disorder (AUD)
The investigators assess whether guanfacine extended release (GXR; 3mg/d) compared with placebo (PBO) will attenuate drinking and drinking-related factors in N=200 men and women with Alcohol Use Disorder (AUD) across 12-weeks.
- Trial name
- NCT06629259
- Testing
- Guanfacine Extended Release (XR)
- Where
- 2 sites in United States
- Volunteers
- 200 people
- Sponsor
- Indiana University
Alcoholism and Alcohol Abuse, Alcohol Use Disorder
Assertive Community Treatment for Alcohol Misuse Disorder Patients Who Are High Utilizers of Emergency Department Services
Background Frequent attenders (FAs) at emergency department (ED) in Singapore hospitals have been increasing over the years. More than half of the FAs are reported to be alcohol-related frequent attenders (ARFA) and they were…
- Conditions
- Alcoholism and Alcohol Abuse, Alcohol Use Disorder, Emergencies
- Trial name
- ARFA (NCT04447079)
- Testing
- Assertive Community Treatment (ACT)
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Khoo Teck Puat Hospital
Liver Diseases, Alcohol Use Disorder
Coronavirus Disease 2019 (Covid-19) Impact on Alcohol-related Liver Disease Patient Outcomes, Care and Alcohol Use
The study consists of a randomized controlled trial evaluating the efficacy and feasibility of a stepped alcohol treatment using telemedicine on unhealthy alcohol use in patients with chronic liver disease receiving care in…
- Trial name
- NCT05191446
- Testing
- Stepped alcohol intervention (SAT) to reduce unhealthy alcohol use, Usual Care (UC)
- Where
- 2 sites in United States
- Volunteers
- 180 people
- Sponsor
- University of California, San Francisco
Cannabis, Alcohol Effect
Ethanol and Cannabinoid Effects on Simulated Driving and Related Cognition
The overarching goal of this study is to characterize the effects of ethanol and cannabinoids on simulated driving and related cognition.
- Conditions
- Cannabis, Alcohol Effect, Driving Under the Influence of Alcohol and Other Drugs
- Trial name
- THC-ETOH (NCT02404688)
- Testing
- Active delta-9-THC, Active Ethanol
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Yale University
Alcoholism, Alcohol Abuse
Zonisamide vs. Placebo in the Treatment of Alcohol Dependence
This is a pilot study designed to examine the potential efficacy and tolerability of zonisamide compared to placebo for the treatment of alcohol dependence.
- Conditions
- Alcoholism, Alcohol Abuse, Alcohol Dependence
- Trial name
- NCT00595556
- Testing
- zonisamide
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- UConn Health
Alcohol Dependence
Topiramate for Hospitalized Patients With Alcoholism: a 12-week Study
12-week, open-label study of topiramate in hospitalized patients with alcoholism
- Trial name
- THoPA-O (NCT01135602)
- Testing
- Topiramate
- Where
- 2 sites in Thailand
- Volunteers
- 150 people
- Sponsor
- Chiang Mai University
Alcohol Drinking, Cannabis
Effects of Inhaled Cannabis on Driving Performance
The purpose of this study is to expand understanding of the effects of cannabis on driving performance with and without the presence of low levels of alcohol.
- Trial name
- NCT01620177
- Where
- United States
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- Gary R Gaffney
Alcohol Abuse/Dependence, Alcohol Use Disorder (AUD)
Ketamine and Neurofeedback as Combined Therapeutic Interventions to Target Glutamatergic Neurotransmission in Alcohol Use Disorder
The goal of this clinical trial is to learn about the effects of the combination of ketamine and realtime functional magnetic resonance imaging (fMRI) neurofeedback training on the treatment of individuals with alcohol use…
- Conditions
- Alcohol Abuse/Dependence, Alcohol Use Disorder (AUD), Alcoholism
- Trial name
- Nektar (NCT06969937)
- Testing
- Ketamine, Real-time fMRI Neurofeedback Training
- Where
- Switzerland
- Volunteers
- 75 people
- Sponsor
- Dr. med. Marcus Herdener
Alcohol Dependence
Efficacy of Topiramate for Hospitalized Patients With Alcoholism
This is a 12-Week, randomized controlled study of topiramate in hospitalized patients with alcoholism
- Trial name
- ETHoPA-R (NCT01145677)
- Testing
- Topiramate
- Where
- 4 sites in Thailand
- Volunteers
- 90 people
- Sponsor
- Chiang Mai University
Alcohol Withdrawal, Alcohol Abstinence
Intravenous Acetate as an Adjunctive Treatment for Alcohol Withdrawal in Hospitalized Patients
Alcohol withdrawal syndrome is a highly morbid condition affecting a substantial percentage of patients hospitalized who have alcohol use disorders, estimated at 5-6% of all hospitalized patients.
- Conditions
- Alcohol Withdrawal, Alcohol Abstinence, Alcohol Use Disorder
- Trial name
- NCT07810946
- Testing
- Sodium Acetate
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- University of Colorado, Denver
Alcohol Addiction
Transcranial Magnetic Stimulation in the Treatment of Addiction
The investigators hypothesize that repetitive transcranial magnetic stimulation (rTMS) on the right side of the head will make craving towards alcohol less severe in recently detoxified alcohol addicted patients.
- Trial name
- MAGENTA (NCT01973127)
- Testing
- Verum rTMS
- Where
- Netherlands
- Volunteers
- 30 people
- Sponsor
- IrisZorg
Alcohol Dependence, Schizophrenia
Treatment With Acamprosate in Patients With Schizophrenia and Comorbid Alcoholism
The aim of this study is to evaluate the safety and efficacy of acamprosate for patients with alcohol dependence and comorbid schizophrenia spectrum disorders.
- Trial name
- NCT00463346
- Testing
- Acamprosate
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- Yale University
Alcohol Use Disorder, Anxiety
Amplification of Positivity for Alcohol Use
The proposed study consists of two phases. During Phase 1, the investigators will recruit a small sample of participants to complete a psychosocial intervention termed Amplification of Positivity (AMP) for individuals…
- Conditions
- Alcohol Use Disorder, Anxiety, Depression
- Trial name
- AMP-A (NCT06030154)
- Testing
- Cognitive Behavioral Therapy, Amplification of Positivity Therapy, Surveys and Interviews
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Laureate Institute for Brain Research, Inc.
Hepatitis C, Alcohol Use Disorder
HCV and Co-morbid Alcohol Use Disorders: A Translational Investigation of Antiviral Therapy Outcomes on CNS Function
The primary objective of this research project is to compare neuropsychiatric functioning, cortical activity, white matter integrity, and immune response among Veterans with and without alcohol use disorder (AUD), before and…
- Trial name
- NCT03902366
- Testing
- Neuropsychological assessment, Neuroimaging
- Where
- United States
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Alcoholism
Combined Pharmacotherapies for Alcoholism (Naltrexone/Ondansetron)
This study will compare the effectiveness of ondansetron (Zofran) and naltrexone (ReVia) both alone and in combination in treating Early Onset Alcoholics versus Late Onset Alcoholics.
- Trial name
- NCT00027079
- Testing
- ondansetron (Zofran), naltrexone (ReVia), Cognitive Behavioral Therapy
- Where
- United States
- Volunteers
- 360 people
- Sponsor
- National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Alcohol Dependence
Effects and Therapeutic Potential of Psilocybin in Alcohol Dependence
This trial is an open-label pilot study (N = 10) designed to assess the effects of psilocybin in alcohol dependent participants, demonstrate the feasibility of the integrated behavioral/pharmacologic intervention, and provide…
- Trial name
- NCT01534494
- Testing
- Psilocybin
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of New Mexico
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