Clinical trials: Algorithms
Cervical Cancer, HPV Infection
Human Papilloma Virus (HPV) Self-collection and Women Adherence
Despite declining mortality in high-income countries, cervical cancer continues to be a public health problem in low and middle -income countries.
- Trial name
- NCT05059015
- Testing
- CERVICAL HPV, SELF SAMPLING HPV
- Where
- Colombia
- Volunteers
- 80 people
- Sponsor
- Instituto Nacional de Cancerologia, Columbia
Heart Failure, Cardiac Output
Validation of CardioMEMS HF System Cardiac Output Algorithm IDE
The investigation will enroll subjects who have been previously implanted with the CardioMEMS™ Pulmonary Artery Sensor. This clinical investigation is twofold; in the first phase (development phase) data collected will be used to…
- Trial name
- VICTOR (NCT05428384)
- Testing
- MRI/ CardioMEMS comparison
- Where
- 8 sites in United States
- Volunteers
- 89 people
- Sponsor
- Abbott Medical Devices
Achilles Tendon Rupture
Achilles Tendon Elongation and Gait Pattern After Rupture.
The objective of this study is to determine if Achilles tendon elongation and gait pattern differ between patients treated using an individualized treatment algorithm and patients treated as usual (two control groups; patients…
- Trial name
- NCT03543943
- Testing
- Individualized treatment of Acute Achilles tendon rupture., Non-operative treatment, Operative treatment
- Where
- Denmark
- Volunteers
- 60 people
- Sponsor
- Hvidovre University Hospital
Diabetes, Type I
Closing the Loop Between Glucose Sensor and Insulin Pump-developing an Algorithm
An open interventional data collection study in order to build a database to close the loop between glucose sensor and insulin pump.
- Trial name
- NCT00541515
- Testing
- continuous glucose sensors and insulin pump
- Where
- Israel
- Volunteers
- 38 people
- Sponsor
- Rabin Medical Center
Out-of-Hospital Cardiac Arrest
Early-onset Pneumonia After Out-of-hospital Cardiac Arrest
Early-onset pneumonia after out-of-hospital cardiac arrest is frequent. An association between early-onset pneumonia and an increase in morbidity has been reported in this population.
- Trial name
- PP-ACR (NCT03355885)
- Where
- France
- Volunteers
- 240 people
- Sponsor
- University Hospital, Brest
Atrial Fibrillation, Venous Thromboses
Pharmacogenetic Dosage Algorithm for Acenocoumarol
The use of coumarins has been a challenge for doctors because of its narrow therapeutic range and they show great inter and intra-individual variability in the dose necessary to achieve an international normalized ratio (INR)…
- Conditions
- Atrial Fibrillation, Venous Thromboses, Cardiac Valve Disease
- Trial name
- NCT03015025
- Testing
- Acenocoumarol
- Where
- Spain
- Volunteers
- 340 people
- Sponsor
- Instituto de Investigación Hospital Universitario La Paz
Myelofibrosis (MF)
A New Diagnostic Algorithm to Non-invasively Track Fibrotic Changes in Myeloproliferative Neoplasms Based on C-C Chemokine Receptor 2 Detection. From Flow Cytometry to the Development of Targeted Positron Emission Tomography Molecular Imaging. Pre-clinical Studies and First In-human Proof of Concept
Chronic "Philadelphia-negative" myeloproliferative syndromes are chronic blood disorders. They include essential thrombocythemia, polycythemia vera, and myelofibrosis.
- Trial name
- GR-MPN (NCT07419178)
- Testing
- Diagnosis of MPN subtypes
- Where
- Italy
- Volunteers
- 265 people
- Sponsor
- Azienda Ospedaliero-Universitaria di Parma
Respiration Disorders, Swallowing Disorder
Artificial Intelligence in Diagnosing Dysphagia Patients
In this prospective study we extracted acoustic parameters using PRAAT from patient's attempt to phonate during the clinical evaluation using a digital smart device.
- Conditions
- Respiration Disorders, Swallowing Disorder, Phonation Disorder, Stroke
- Trial name
- NCT05098808
- Testing
- Acoustic features (from signals obtained during phonation)
- Where
- South Korea
- Volunteers
- 449 people
- Sponsor
- The Catholic University of Korea
Atrial Fibrillation (AF), Atrial Fibrillation Patients Treated With the FARAPULSE™ PFA System
P-wave Duration and Local Potential as Predictors of AF Recurrence Following Pulmonary Vein Isolation
Atrial fibrillation (AF) is the most prevalent sustained cardiac arrhythmia worldwide and is associated with substantial morbidity, mortality, and healthcare utilization.
- Conditions
- Atrial Fibrillation (AF), Atrial Fibrillation Patients Treated With the FARAPULSE™ PFA System, Atrial Fibrillation (Paroxysmal), Pulmonary Vein Isolation
- Trial name
- FOLLOW-AF (NCT07471308)
- Testing
- AF Recurrence RIsk Assessment post pulmonary vein isolation
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- CathVision ApS
Severe Persistent Asthma
A Pragmatic Trial of Corticosteroid Optimisation in Severe Asthma
This study explores if a composite biomarker strategy predicts exacerbation risk in patients with asthma on high dose inhaled corticosteroid (+/-long-acting beta agonist) treatment and to evaluate the utility of this composite…
- Trial name
- NCT02717689
- Testing
- Biomarker based adjustment of corticosteroid dose
- Where
- 11 sites in United Kingdom
- Volunteers
- 300 people
- Sponsor
- Belfast Health and Social Care Trust
Type 1 Diabetes Mellitus, Autoimmune Diabetes
Medtronic Minimed Overnight Closed-Loop System
To test the function and safety of the Medtronic Overnight Closed Loop (OCL) System in a closely monitored 12 hour overnight inpatient study.
- Conditions
- Type 1 Diabetes Mellitus, Autoimmune Diabetes, Juvenile-Onset Diabetes, Diabetes, Mellitus, Type 1
- Trial name
- NCT01881009
- Testing
- Hybrid Closed-loop System, Sensor-augmented pump
- Where
- United States
- Volunteers
- 37 people
- Sponsor
- Bruce A. Buckingham
Traumatic Brain Injury, Acute Brain Injuries
Automated Measurement of Optic Nerve Sheath Diameter
Optic Nerve Ultrasound (ONUS) is a promising non-invasive tool for the detection of raised Intracranial Pressure (ICP). Variability in the optimal Optic Nerve Sheath Diameter (ONSD) threshold corresponding to elevated ICP in…
- Conditions
- Traumatic Brain Injury, Acute Brain Injuries, Intracranial Hypertension
- Trial name
- NCT02786706
- Testing
- Optic nerve ultrasound
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- University of Michigan
Bone Lesion
Artificial Intelligence and Bone Tomoscintigraphies Achieved With CZT Camera
This study aimed to determine whether the whole-body bone Single Photon Emission Computed Tomography (SPECT) recording times of around 10 minutes, routinely provided by a high-sensitivity 360 degrees cadmium and zinc telluride…
- Trial name
- IATOS (NCT06281015)
- Testing
- Whole-body bone single photon emission tomography (SPECT) for detection or follow-up of bone metastasis
- Where
- France
- Volunteers
- 19 people
- Sponsor
- Central Hospital, Nancy, France
Neuroendocrine Carcinoma of Lung, Neuroendocrine Carcinoma of Thymus
CompArative Analysis Between, Thymic, pulmonaRy and Pancreatic Well Differentiated High Grade Neuroendocrine Tumors
The study involves the enrollment of 34 patients diagnosed with advanced thymic, pulmonary and duodeno-pancreatic well-differentiated high grade neuroendocrine tumors (Ki-67 > 20%).
- Trial name
- LINEAR (NCT07429851)
- Where
- Italy
- Volunteers
- 34 people
- Sponsor
- European Institute of Oncology
Sinus Node Disease, AV Block
Ingenio Device Algorithm Study
The purpose of the IVORY Study is to gather data to support global submissions/approvals for some models of the Ingenio device family.
- Conditions
- Sinus Node Disease, AV Block, Heart Failure
- Trial name
- IVORY (NCT01441583)
- Testing
- RAAT, RYTHMIQ
- Where
- 21 sites in Austria, Belgium and 10 more
- Volunteers
- 139 people
- Sponsor
- Boston Scientific Corporation
Dyspnea, Heart Failure
The Triple A Initiative Study ("Aktionsbündnis Akute Atemnot")
Acute dyspnea is a common chief complaint of patients presenting to the emergency department. Patients with acute dyspnea display a high mortality rate.
- Trial name
- NCT02049853
- Testing
- NTproBNP measurement with point of care device "Cobash232" in the POCT group
- Where
- 6 sites in Germany
- Volunteers
- 67 people
- Sponsor
- Prof. Dr. Michael Christ
Diabetes
Data Therapy Collection to Evaluate Performances of an Automated Insulin Titration Algorithm Compared to Standard Method of Titration
A data collection of blood glucose values, insulin, meal composition will be performed for a period of two months, to evaluate the performances of an automated insulin titration algorithm
- Trial name
- GLUCAL3 (NCT05098301)
- Where
- France
- Volunteers
- 30 people
- Sponsor
- University Hospital, Montpellier
Genital Herpes
Serologic Assays for the Diagnosis of Herpes Simplex Virus Type 2
The purposes of this study are: To determine the accuracy of commercially available serologic assays in diagnosing patients with herpes simplex virus type 2 (HSV-2); To assess the sensitivity and specificity of the commerical…
- Trial name
- NCT01112956
- Where
- 3 sites in United States
- Volunteers
- 2,500 people, healthy volunteers welcome
- Sponsor
- Centers for Disease Control and Prevention
Anesthesia
The TI.VA Algorithm: A First-in-Humans Test.
The TI.VA algorithm is a new method to titrate the anesthetic drug concentrations whenever the planned level of anesthesia results to be not appropriate to blunt the patient's reaction to surgical stimulation.
- Trial name
- TIVAly (NCT05199883)
- Testing
- TI.VA algorithm: decision support system
- Where
- Italy
- Volunteers
- 5 people
- Sponsor
- Fondazione IRCCS Istituto Nazionale dei Tumori, Milano
Diabetes, Diabetes Mellitus, Type 2
INITIATE Plus (INITiation of Insulin to Reach A1c TargEt) Study
This trial is conducted in the United States of America (USA). The purpose of this study is to compare the effectiveness and safety of a biphasic insulin aspart standard titration regimen when coupled with dietary intervention to…
- Trial name
- INITIATE plus (NCT00101751)
- Testing
- biphasic insulin aspart, dietary regimen
- Where
- United States
- Volunteers
- 4,877 people
- Sponsor
- Novo Nordisk A/S