Clinical trials: Aligner Therapy
Endocrine Disruptors
A Comparison of Direct 3D Printed Clear Aligner System and Indirect Clear Aligner Systems With Fixed Orthodontic Treatment in Terms of Endocrine Disrupting Monomer Release, Treatment Effectiveness and Efficiency
The aim of this study is to evaluate the release of endocrine disrupting monomers from clear aligners as a result of exposure to intraoral factors by measuring their concentration in saliva and to evaluate their reliability of…
- Trial name
- NCT06685029
- Testing
- Clear aligner treatment, Fixed Orthodontic Appliance Treatment
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people
- Sponsor
- Ahmet Yağcı
Orthodontic Treatment, Saliva
Salivary Flow, pH, and Buffering Capacity in Fixed and Clear Aligner Orthodontic Treatment
Study Design: A randomized controlled trial with two parallel arms and an allocation ratio of 1:1. Setting: The study will be conducted in the orthodontic department of Riyadh Elm University hospitals in Riyadh City, Saudi…
- Trial name
- NCT07397871
- Testing
- Fixed orthodontic appliances, Clear Aligner Treatment
- Where
- Saudi Arabia
- Volunteers
- 40 people
- Sponsor
- Riyadh Elm University
Eating Behaviors
Eating Attitudes in Orthodontic Patients
This study was conducted on 70 individuals who presented to the Orthodontics Department of the Faculty of Dentistry at Necmettin Erbakan University.
- Trial name
- NCT07038772
- Testing
- Orthodontic treatment
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Konya Necmettin Erbakan Üniversitesi
Open Bite
Investigate the Effectiveness of 3D-printed Shape Memory Aligners in the Treatment of Anterior Open Bite
The goal of this randomised clinical trial study is to investigate 3D-printed shape memory aligners in the treatment of anterior dental open bite adult patients. The main questions it aims to answer are: 1.
- Trial name
- NCT07420777
- Testing
- SMA with attachment, SMA without attachments, CA with attachment
- Where
- Iraq
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Kufa University
Dental Plaque Accumulation, Oral Hygiene in Orthodontic Patients
Comparison of Plaque Removal Efficacy of Different Toothbrushes in Clear Aligner Patients
This study aims to compare the effectiveness of manual and powered toothbrushes in removing dental plaque in patients undergoing clear aligner orthodontic treatment.
- Conditions
- Dental Plaque Accumulation, Oral Hygiene in Orthodontic Patients, Clear Aligner Therapy
- Trial name
- NCT07383636
- Testing
- Manual Toothbrush, Powered Toothbrush
- Where
- Turkey (Türkiye)
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Mersin University
Root Resorption, Pain Perception
AI-Designed Clear Aligners: A Randomized Clinical Trial
The goal of this clinical trial is to evaluate the clinical performance and validity of applying AI-based TruRoot-designed clear aligners in adult orthodontic patients.
- Conditions
- Root Resorption, Pain Perception, Treatment Duration
- Trial name
- NCT06968325
- Testing
- AI-based TruRoot group:, Conventional clear aligner group
- Where
- Iraq
- Volunteers
- 40 people
- Sponsor
- University of Baghdad
Crowding, Tooth
The Effectiveness of Clear Aligner and Traditional Fixed Appliances in Achieving Good Occlusion in Complex Orthodontic Cases
Patients who have severe crowding that requires four premolars extraction will be treated in this study. The efficacy and effectiveness of in-house clear aligners therapy compared with vestibular fixed appliances in the treatment…
- Trial name
- NCT05500456
- Testing
- Clear aligners, Fixed appliances
- Where
- Syria
- Volunteers
- 36 people
- Sponsor
- Damascus University
Class III Malocclusion
Mandibular Sequential Distalization Versus Class III Elastics With Clear Aligners in Class III Patients
Distalizing mandibular molars may be indicated for patients with minor skeletal Class III discrepancies or in Class III subjects with mild crowding.
- Trial name
- NCT06859606
- Testing
- Lower molar distalization, Class III elastics
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- Saint Camillus International University of Health Sciences
Composite Resins, Clear Aligner Therapy
Color Stability and Fluorescence Properties of Two Aligner Attachment Composites
This split mouth study aims to evaluate whether 2 different composite materials used for making clear aligner attachments change color over time and do they have different fluorescent characteristics when illuminated with…
- Trial name
- NCT07806214
- Testing
- GC Aligner Connect, VOCO AlignerFlow LC
- Where
- Turkey (Türkiye)
- Volunteers
- 39 people
- Sponsor
- Marmara University
Tooth Crowding, Malocclusion
Predictability of Orthodontic Tooth Movement With Invisalign Aligners
Together with the increased adult patient demand for orthodontic treatment and the push toward increasingly personalized treatment, technology developments have resulted in a growing worldwide demand for clear aligners, to the…
- Conditions
- Tooth Crowding, Malocclusion, Malocclusion, Angle Class II, Malocclusion, Class I/II
- Trial name
- NCT05356780
- Testing
- Aligner
- Where
- Italy
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- University of Turin, Italy
Aligner Treatment
Biochemical Evaluation of Periodontal Effects of Orthodontic Treatment with Aligners
The aim of this study was to determine the effect of orthodontic treatment with aligner on changes in osteoprotegerin (OPG) and receptor activator of NF-κB ligand (RANKL) levels in saliva samples and to investigate the possible…
- Trial name
- NCT06646705
- Testing
- Saliva obtaining
- Where
- Turkey (Türkiye)
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Izmir Katip Celebi University