Clinical trials: Alignment
Osteoarthritis (OA) of the Knee
Native Alignment in the Setting of an Arthritic Knee in Total Knee Arthroplasty
The goal of this clinical trial is to learn if preparing the target alignment of the operative side in total knee arthroplasty (TKA) based on the non-arthritic side will give the patient better overall alignment, function, and…
- Trial name
- NCT06617338
- Testing
- CT scan unilateral knee, CT scan bilateral knee
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- University of Louisville
Surgical Incision, Malocclusion
Efficacy of Piezosurgey Corticotomy (a Minimally Invasive Surgical Technique) in Accelerating Orthodontic Alignment
Applying flapless piezocision corticotomies on the alveolar bone and separating anterior mandibular teeth using a piezosurgery device (i.e.
- Trial name
- NCT02977221
- Testing
- Piezosurgery
- Where
- Syria
- Volunteers
- 36 people
- Sponsor
- Damascus University
Arthroplasty, Replacement, Hip
Pelvic Alignment Level (PAL) Instrument Evaluation
The study is conducted to evaluate the performance of the Pelvic Alignment Level (PAL) instrument in achieving desired acetabular position, desired leg length and offset after Total Hip Replacement (THR) reconstruction.
- Trial name
- PAL (NCT01312428)
- Testing
- Pelvic Alignment Level (PAL) Instrument, No Pelvic Alignment Level (PAL) Instrument
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- Stryker Orthopaedics
Crossed Pelvis Syndrome
Effects of Using Customized Insoles With Anterior or Posterior Plantar Support in Cross-pelvis Syndrome and Perception of Body Alignment in Young Adults: a Randomized Clinical Trial
INTRODUCTION: Custom insoles with anterior or posterior support are described in the literature mainly for the treatment of foot and knee dysfunctions and this therapeutic effect extends to the promotion of biomechanical…
- Trial name
- NCT03350867
- Testing
- Personalized Insole Group
- Where
- Brazil
- Volunteers
- 15 people
- Sponsor
- Universidade Federal de Pernambuco
Morbid Obesity Requiring Bariatric Surgery, Neck Pain Musculoskeletal
Changes in Cervical Posture, Cervical Function, and Neck Pain After Sleeve Gastrectomy
Obesity may contribute to neck pain, altered cervical posture, and impaired cervical function through increased mechanical loading, changes in body alignment, and reduced muscle performance.
- Trial name
- NCT07813429
- Testing
- Laparoscopic Sleeve Gastrectomy
- Where
- Turkey (Türkiye)
- Volunteers
- 25 people
- Sponsor
- Haydarpasa Numune Training and Research Hospital
Varus Deformity
Assessment of Foot Alignment and Pressure After Correction of Varus Knee by High Tibial Osteotomy or Total Knee Replacement
This study evaluated the change in foot alignment after TKA or HTO by prospectively analyzing the correlation between the knee joint and the foot deformity, the post-operative improvement in the foot deformity, and the long-term…
- Trial name
- NCT05314972
- Volunteers
- 200 people
- Sponsor
- Assiut University
Orthodontic Treatment
Appointment Intervals and Orthodontic Tooth Movement
The purpose of this study is to investigate rapidity of tooth alignment in a randomised clinical trial of orthodontic patients allocated randomly into two different appointment intervals groups.
- Trial name
- NCT04050657
- Testing
- appointment interval
- Where
- United Kingdom
- Volunteers
- 46 people
- Sponsor
- Guy's and St Thomas' NHS Foundation Trust
Knee Osteoarthritis, Osteoarthritis (Knee)
Manual Arthroplasty Versus VELYS Robotic-Assisted Solution Functional Alignment Arthroplasty for Knee Osteoarthritis
The goal of this clinical trial is to learn if the VELYS Robotic-Assisted Solution (VRAS) device helps to improve outcomes from total knee replacement, when compared to regular non-robotic-assisted total knee replacement in the…
- Conditions
- Knee Osteoarthritis, Osteoarthritis (Knee), Osteo Arthritis of the Knee, Osteo Arthritis
- Trial name
- MARVEL Project (NCT07551856)
- Testing
- Robot-Assisted Functionally Aligned Total Knee Replacement, Manual Total Knee Arthroplasty
- Where
- United Kingdom
- Volunteers
- 346 people
- Sponsor
- Golden Jubilee National Hospital
Orthodontic Tooth Movement, Tooth Alignment
Effect of 3 Week vs 6 Week Orthodontic Appointment Intervals on Teeth Alignment
Effect of 3 week vs 6 week orthodontic appointment intervals on teeth alignment in patients with moderate to severe dental crowding: a randomized clinical trial.
- Trial name
- NCT06032702
- Testing
- tooth alignment
- Where
- Pakistan
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Bkahtawar Amin Medical and Dental College Multan
Hernia
Patient Priorities Aligned Discrete Decision Making for Older Adults With Multiple Chronic Conditions.
The purpose of the study is to to evaluate an artificial intelligence (AI) powered large language model (LLM) chatbot -PrioritiesAI -that assists patients in understanding, clarifying, and communicating their health priorities…
- Trial name
- NCT07848386
- Testing
- AI Chatbot
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- The University of Texas Health Science Center, Houston
Mitochondrial Degradation, Autophagy
Mitophagy and Mitochondrial DNA Dynamics During Ramadan Dry Fasting vs 16:8 Time-Restricted Feeding
This study investigates how different types of fasting affect cell health, specifically focusing on how mitochondria (the energy-producing parts of cells) are cleared and renewed.
- Conditions
- Mitochondrial Degradation, Autophagy, Fasting, Healthy Volunteers
- Trial name
- MITO FAST (NCT07638696)
- Testing
- Ramadan Intermittent Dry Fasting (Sawm), 16:8 Time-Restricted Feeding (TRF)
- Where
- Cyprus
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Bahcesehir Cyprus University
Knee Osteoarthritis (Knee OA)
Intelligent Precision Knee Preservation System for Knee Osteoarthritis
The goal of this clinical trial is to verify whether the "dynamic dual-mode alignment optimization + intelligent precision knee-preserving system" (integrating static/kinematic target alignment, CT-based preoperative…
- Trial name
- NCT07284524
- Testing
- HTO procedure
- Where
- China
- Volunteers
- 150 people
- Sponsor
- First Affiliated Hospital of Wenzhou Medical University
Complication of Hemodialysis
Effects of Simple Sodium Alignment on Clinical Outcomes
A difference between dialysate and serum sodium concentration leads to diffusive sodium transfer across the dialyzer membrane. The consequences of diffusive sodium flux into the patient can be chronic sodium overload leading to…
- Trial name
- NCT01825590
- Testing
- Dialysate and serum sodium concentration aligned
- Where
- United States
- Volunteers
- 148 people
- Sponsor
- Renal Research Institute
Patellofemoral Maltracking
Relationship Between The Quadriceps Muscle Stiffness And Patellar Alignment For Healthy People
Patellofemoral pain is a common disease, and it often couples with patellar malalignment. Previously, imbalance of the different quadriceps muscle heads was believed to be a causative factor of patellar malignment.
- Trial name
- NCT04982679
- Where
- Hong Kong
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Arthropathy, Knee Replacement
The Medacta GMK SpheriKA Post-Marketing Surveillance Study
This is a Post-Marketing Surveillance of GMK SpheriKA knee stem prosthesis.
- Trial name
- NCT05459948
- Testing
- GMK SpheriKA
- Where
- 4 sites in France, Italy and 1 more
- Volunteers
- 281 people
- Sponsor
- Medacta International SA
Spinal Mobility, Thoracic Spine
Effects of Thoracic Spine Exercises on Spinal Alignment and Mobility in Male Soccer Players
Thoracic spine mobility is essential for trunk stability, rotational movement, and athletic performance in soccer players. This study aimed to investigate the effects of adding thoracic spine exercises to routine soccer training…
- Trial name
- NCT07253415
- Testing
- Thoracic spine exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Izmir Katip Celebi University
Mental Disorder, Substance Use Disorders
Supported Employment in Patient Aligned Care Teams
In response to the Rehabilitation Research and Development (RR\&D) Deployment Health Research, this study addresses the delivery of an evidenced-based vocational rehabilitation, specifically Individual Placement and Support…
- Conditions
- Mental Disorder, Substance Use Disorders, Posttraumatic Stress Disorder, Major Depressive Disorder
- Trial name
- NCT02400736
- Testing
- Individual Placement and Support (IPS), Treatment as Usual Vocational Rehabilitation/Transitional Work (TUA-VR)
- Where
- United States
- Volunteers
- 119 people
- Sponsor
- VA Office of Research and Development
Upper Crossed Syndrome, Upper Cross Syndrome
Dynamic Neuromuscular Stabilization Versus Corrective Exercises in Upper Cross Syndrome
The purpose of the study will be to investigate dynamic neuromuscular stabilization versus National American Academy of Sports Medicine (NASM) corrective exercises on pain, functional disability, cranio-vertebral angle, forward…
- Conditions
- Upper Crossed Syndrome, Upper Cross Syndrome, Upper Crossed Syndorme
- Trial name
- DNS/NASM (NCT07698392)
- Testing
- Dynamic neuromuscular stabilization, NASM corrective exercises
- Where
- Egypt
- Volunteers
- 45 people
- Sponsor
- Cairo University
Obesity, Overweight
The Peer Assisted Lifestyle Intervention
The PAL intervention uses a new software tool delivered on tablets to facilitate 5As-based weight management counseling with a peer health coach and the VA PACT healthcare team to promote goal-setting, behavior change, and weight…
- Trial name
- PAL (NCT03163264)
- Testing
- Peer Assisted Lifestyle, Enhanced Usual Care
- Where
- United States
- Volunteers
- 301 people
- Sponsor
- VA Office of Research and Development
Mechanical Low Back Pain
Efficacy and Influence of Pilates Based Physical Therapy Exercises for Low Back Pain
An assessment of the effectiveness of Pilates based physical therapy exercises for patients with low back pain (LBP) and its influence on spinal movement and patient reported functional disability.
- Trial name
- NCT02622789
- Testing
- Pilates Exercises
- Where
- Taiwan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- China Medical University Hospital