Clinical trials: Alignment
Transcatheter Aortic Valve Replacement, Transcatheter Aortic Valve Implantation
TAVR: The Impact of Prothesis Positioning on Valvular and Coronary Hemodynamics
The aim of this clinical study is to learn more about the effects of TAVR-prosthesis positioning on hemodynamics and the coronary arteries. The main questions it aims to answer are: 1.
- Conditions
- Transcatheter Aortic Valve Replacement, Transcatheter Aortic Valve Implantation, Commissural Alignment, Commissural Misalignment
- Trial name
- NCT06896227
- Testing
- transthoracic echocardiography
- Where
- Germany
- Volunteers
- 100 people
- Sponsor
- Heinrich-Heine University, Duesseldorf
Malocclusion
The Effect of OrthoPulse™ Photobiomodulation on Tooth Movement and Treatment Time When Used With Invisalign Treatment
The aim of the study is to determine if, and to what degree photobiomodulation treatment with OrthoPulse has an effect on the rate of tooth movement during alignment for patients receiving Invisalign orthodontic aligner treatment.
- Trial name
- NCT02954133
- Testing
- Invisalign (7 day), Invisalign (5 day), OrthoPulse
- Where
- 4 sites in United States
- Volunteers
- 167 people, healthy volunteers welcome
- Sponsor
- Biolux Research Holdings, Inc.
Exotropia, Exophoria
A-eyedrops on Ocular Alignment and Binocular Vision
Atropine is a non-selective muscarinic acetylcholine (M) receptor antagonist that paralyzes the ciliary muscle, dilates the pupil, and reduces the power of accommodation.
- Conditions
- Exotropia, Exophoria, Myopia
- Trial name
- NCT05379855
- Testing
- 0.01% atropine eye drops, 0.05% atropine eye drops
- Where
- China
- Volunteers
- 339 people
- Sponsor
- Eye & ENT Hospital of Fudan University
Orthodontic Appliance
Pulpal Blood Flow Changes Using SuperElastic 0.018-inch Nickel Titanium
to record pulpal blood flow (PBF) changes associated with using 0.018-inch Nickel Titanium (NiTi) as the first alignment archwire during fixed orthodontic treatment.
- Trial name
- NCT04378205
- Testing
- 0.014-inch NiTi on one side /0.018-inch NiTi on the other side, 0.016-inch NiTi on one side /0.018-inch NiTi on the other side
- Where
- Jordan
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Jordan University of Science and Technology
Strabismus; Intermittent
Eye Alignment and Eye Control Changes Through Follow up Period After Application of Eye Exercises Post Strabismus Surgery
The aim of this study is to determine the patient status through its follow up period and weather the eye alignment and eye control are as the same as the last physiotherapy treatment session or there is any deterioration of them.
- Trial name
- NCT06543212
- Testing
- physiotherapy exercises
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Amany Refaat Mohamed Abdel Wahid
Dental Malocclusion
Laser in Orthodontic Leveling and Alignment
to evaluate the outcome of LLLT regarding leveling and alignment of the mandibular anterior segment.
- Trial name
- NCT04376164
- Testing
- low level laser therapy
- Where
- Egypt
- Volunteers
- 26 people
- Sponsor
- Tharwat osman Mohi Eldeen Elshehawy
Eye Diseases, Retinal Disease
Advancing Pediatric Retinal Imaging With Auto-aligned OCT
The goal of the current study is to conduct a pilot study to test a new version of the handheld OCT device capable of auto-alignment to image the retina in adult volunteers, and adult and pediatric patients in clinic.
- Conditions
- Eye Diseases, Retinal Disease, Glaucoma, Optic Nerve Diseases
- Trial name
- NCT06841575
- Testing
- Auto-aligned OCT
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Duke University
Knee Injuries
Knee Alignment Contributions to Anterior Cruciate Ligament (ACL) Injury
This study evaluates the the anatomic factors of the knee that may predispose to ACL injury.
- Trial name
- NCT00855023
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- The Orthopaedic Center, Maryland
Stroke
Time Course of a Misperception of Verticality and Its Characteristics in Post-stroke Participants
Little is known about the time course of verticality perception after stroke. This study aims to assess: The time course of verticality perception (Subjective Visual, Haptic and Postural Vertical; resp., SVV, SHV, SPV); The…
- Trial name
- NCT05978596
- Where
- 2 sites in Belgium
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Universiteit Antwerpen
Pain
Comparison of Self-ligating and Conventional MBT Brackets Regarding Alignment Efficiency and Pain Perception
The rate of Orthodontic tooth movement affects the efficacy and time duration of the treatment. One of the key factors, during the initial alignment phase, is the amount of the force that the arch-wire applies to the dentition.
- Trial name
- NCT06895083
- Testing
- self ligating brackets
- Where
- Pakistan
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Shoaib Rahim
Low Back Pain, Pelvic Malalignment
Neck Exercises for Improving Pelvic Alignment and Low Back Pain
This study aimed to investigate whether a three-dimensional nuchal exercise program is associated with changes in pelvic alignment and low back pain in adults.
- Conditions
- Low Back Pain, Pelvic Malalignment, Postural Imbalance
- Trial name
- NEPAL (NCT07573722)
- Testing
- Three-Dimensional Nuchal Exercise Program
- Where
- Taiwan
- Volunteers
- 30 people
- Sponsor
- Yuanpei University of Medical Technology
Postural Assessment, Body Posture
Validity and Reliability of the DeepClinic Posture Assessment Application
Posture assessment is widely used in sports medicine, physiotherapy, and rehabilitation to identify body alignment problems and support clinical decision-making.
- Conditions
- Postural Assessment, Body Posture, Postural Alignment
- Trial name
- NCT07702331
- Testing
- DeepClinic Posture Assessment, APECS Posture Analysis System
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Istanbul Gelisim University
Sports Injury
The Gender-Specific Effect of Different Instruction Training
Feedback is incorporated into training programs to prevent injuries. The superiority of several feedback techniques is still debated and there is a need for gender specific studies.
- Trial name
- NCT06746454
- Testing
- Video Instructed Training Group, Verbal Combined Focus Instructed Training Group
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Bahçeşehir University
Frozen Shoulder
3-Dimensional Shoulder Complex Pain Alignment (3-D SPA) Mobilization on Frozen Shoulder.
Ongoing research aims to assess the enhancement of shoulder mobility by specifically addressing restrictions in all three planes of movement.
- Trial name
- NCT06530602
- Testing
- 3 D SPA (shoulder complex pain alignment) Moblization, Shoulder Moblization (KaltenBorn)
- Where
- Pakistan
- Volunteers
- 36 people
- Sponsor
- Riphah International University
Glaucoma
Comparison of Optic Nerve Head and Retinal Nerve Fiber Layer Parameters Derived From Two Different Methods of Scan Alignment
This prospective, monocentric, non-invasive clinical study is designed to measure normal structural parameters of the optic nerve head, the peripapillary retinal nerve fiber layer, and the macula using the Heidelberg Spectralis…
- Trial name
- NCT02666144
- Testing
- Spectralis OCT
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Heidelberg Engineering GmbH
Arthropathy of Knee
Comparative Effect of Mechanical and Functional Alignment in Bilateral Total Knee Arthroplasty on Ankle Alignment
Mechanical alignment (MA) in total knee arthroplasty (TKA) is the most commonly used with well-documented long-term results, however 20% of patients express dissatisfaction following primary TKA.
- Trial name
- NCT06259032
- Testing
- Mechanical alignment, Functional alignment
- Where
- Thailand
- Volunteers
- 20 people
- Sponsor
- Department of Medical Services Ministry of Public Health of Thailand
Muscle Weakness, Postural Balance
Effects of a Multidisciplinary Intervention on Muscle Strength, Posture, and Balance in Older Adults After an Earthquake
This randomized controlled trial evaluated the effects of a 12-week multidisciplinary intervention on muscle strength, postural alignment, and balance in older adults living in temporary container settlements following the…
- Conditions
- Muscle Weakness, Postural Balance, Physical Functional Performance, Frail Elderly
- Trial name
- NCT07910981
- Testing
- Multimodal Intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Kahramanmaras Sutcu Imam University
Cervical Disc Degeneration
Compare Different Cervical Anterior Discectomy Procedures by After Procedure Sagittal Alignment on Radiograph
Patients with single-level cervical degenerative disc disease commonly undertook anterior discectomy. To compare the effect of anterior cervical discectomy without fusion (ACD), anterior cervical discectomy with fusion by…
- Trial name
- NCT03360409
- Testing
- ACD, ACDF, ACDA
- Volunteers
- 150 people
- Sponsor
- Peking University People's Hospital
Osteo Arthritis Knee
Kinematic- Versus Ligament-balanced Mechanical Alignment in TKA
A promising new approach in total knee arthroplasty (TKA) for severe osteoarthritis of the knee joint is the the kinematic aligned procedure (KA).
- Trial name
- NCT04436211
- Testing
- Total Knee Arthroplasty
- Where
- Austria
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Medical University of Graz
Breast Cancer, Optical Surface Monitoring Technology
Optical Surface Monitoring Technology-Guided Large-Segment Radiotherapy for Breast Cancer
This study is a single-center,blinded, efficacious, phase III randomized clinical trial initiated by investigators. The primary objective is to investigate the use of Surface Guided Radiation Therapy (SGRT) in combination with…
- Conditions
- Breast Cancer, Optical Surface Monitoring Technology, Large-segment Radiotherapy
- Trial name
- NCT05804916
- Testing
- Surface Guided Radiation Therapy (SGRT)
- Where
- China
- Volunteers
- 556 people
- Sponsor
- Peking Union Medical College Hospital