Clinical trials: Alignment
Leveling and Alignment of Teeth
Effect of Changing the Activation Frequency of the Arch Wires on the Rate of Leveling and Alignment in Moderate Crowding Cases
Leveling and alignment is the first stage in the orthodontic treatment, performed for every patient .The archwire are usually changed every 4 weeks for reactivation of the force on the teeth.
- Trial name
- NCT04106141
- Testing
- 6 weeks changing of archwire, 4 weeks changing of archwire
- Volunteers
- 22 people
- Sponsor
- Cairo University
Osteoarthritis, Knee, Joint Disease
Matched Pair Study - Kinematic Vs Mechanical Alignment
The aim of this study is to evaluate postoperative knee function after total knee arthroplasty performed according to the anatomical alignment and compare these results to those of a matched historical cohort of patients operated…
- Trial name
- NCT03446391
- Testing
- Kinematic alignment, Mechanical alignment, GMK Sphere®
- Where
- Germany
- Volunteers
- 50 people
- Sponsor
- Medacta International SA
Dental Malocclusion, Angle Class II
BRIUS Vs FFA Efficiency
The purpose of this study is to compare the Full Fixed Preadjusted appliances (regular braces) when to the BRIUS system.
- Conditions
- Dental Malocclusion, Angle Class II, Angle Class I, Crowding, Tooth
- Trial name
- NCT04347018
- Testing
- BRIUS
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- State University of New York at Buffalo
Neuro-Ophthalmology
Safety and Normative Data With Neos™
The goal of this clinical study is to collect standard data for the medical device neos™. neos™ is a system that shows images and measures the resulting eye movements and pupil size. Collecting standard data involves three steps.
- Trial name
- neos-SNOW (NCT07258212)
- Where
- 3 sites in Switzerland
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- machineMD AG
Alignment
Patient-specific Instruments as a Standard Procedure in Total Knee Arthroplasty
Description of logistics, learning curve and radiological results in 70 patients treated with patient specific instrumentation in total knee arthroplasty as a standard procedure
- Trial name
- NCT01781598
- Testing
- Total knee arthroplasty (TKA) (Smith &Nephew®)
- Where
- Austria
- Volunteers
- 73 people
- Sponsor
- Orthopedic Clinic Gersthof
Knee Osteoarthritis, Bone; Deformity, Congenital
COREV 2.0 PMCF-Study on Manual and Navigated Revision Knee Patients
The Columbus® Revision endoprosthetic system is bearing the CE-mark. This means that within the scope of this observational study the patient will not be subjected to any additional stressful, study-related medical examinations…
- Conditions
- Knee Osteoarthritis, Bone; Deformity, Congenital, Prosthesis Failure, Prosthesis-Related Infections
- Trial name
- COREV (NCT05113303)
- Testing
- Navigated Revision Total Knee Arthroplasty, Manual Revision Total Knee Arthroplasty
- Where
- Spain
- Volunteers
- 100 people
- Sponsor
- Aesculap AG
Idiopathic Scoliosis, Spinal Curvatures
UNiD Rods Register
Retro-prospective study allowing inclusion of patients with spinal deformities treated by patient-specific rods (UNiD). This study aims to assess performance, clinical outcomes and safety
- Conditions
- Idiopathic Scoliosis, Spinal Curvatures, Spondylolisthesis, Degenerative Scoliosis
- Trial name
- NCT02926404
- Testing
- UNiD Rods
- Where
- 13 sites in Belgium, France and 1 more
- Volunteers
- 743 people
- Sponsor
- Medicrea International
Osteoarthritis, Knee
Efficacy and Safety of NAVIO
The goal of the study is to compare the efficacy, safety and costs of the NAVIO™ system with the conventional intramedullary alignment guide for total knee replacement in a clinical setting.
- Trial name
- NCT04230616
- Testing
- total knee arthroplasty, CT scan
- Where
- Belgium
- Volunteers
- 180 people
- Sponsor
- Sint-Trudo Hospital
Mechanical Low Back Pain
Efficacy and Influence of Pilates Based Physical Therapy Exercises for Low Back Pain
An assessment of the effectiveness of Pilates based physical therapy exercises for patients with low back pain (LBP) and its influence on spinal movement and patient reported functional disability.
- Trial name
- NCT02622789
- Testing
- Pilates Exercises
- Where
- Taiwan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- China Medical University Hospital
Glenohumeral Internal Rotation Deficit, Pelvic Misalignment
Comparing the Effects of Pelvic Alignment Versus Diaphragmatic Breathing on Shoulder Range of Motion
The goal of this research study is to compare the effects of pelvic alignment versus diaphragmatic breathing on range of motion in the shoulder joint in both athletic and nonathletic population.
- Conditions
- Glenohumeral Internal Rotation Deficit, Pelvic Misalignment, Diaphragmatic Breathing
- Trial name
- NCT04255355
- Testing
- Pelvic alignment and forceful expiration, Pelvic repositioning exercise, Diaphragmatic breathing exercise
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of North Georgia
Strabismus, Esotropia
Risk Factors And Surgical Outcomes Of Strabismus Reoperation
Horizontal strabismus, commonly known as inward or outward deviation of the eyes, is a frequent eye condition that may require surgical correction.
- Conditions
- Strabismus, Esotropia, Exotropia
- Trial name
- RSOR (NCT07446621)
- Testing
- Horizontal Strabismus Reoperation
- Where
- Egypt
- Volunteers
- 62 people
- Sponsor
- Assiut University
Osteoarthritis, Knee
Comparison Between Robotic-arm Assisted Total Knee Replacement and Traditional Total Knee Replacement
This is a multicenter, prospective, and case-control study. Five joint centers and 100 participants will be included. The study group used robotic-assisted modified kinematic alignment total knee replacement, and the control…
- Trial name
- NCT05391152
- Testing
- robotic assisted total knee replacement, traditional total knee replacement
- Volunteers
- 100 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Multiple Chronic Conditions
Patient Priority Care for Older Adults With Multiple Chronic Conditions
Healthcare for older adults with multiple chronic conditions (MCCs) is burdensome and of uncertain benefit, resulting in unwanted and unhelpful care.
- Trial name
- PPC-CCF (NCT04510948)
- Testing
- Patient Priorities Care
- Where
- United States
- Volunteers
- 264 people
- Sponsor
- The Cleveland Clinic
Impacted Canine
Evaluation of the Periodontal Status After the Treatment of Palatally Impacted Canines Using Acceleration Procedures
Impacted canine causes many problems for patients, such as damage to the adjacent teeth roots, effects on gingival tissues, aesthetic problems, difficulty, and prolonged orthodontic treatment duration.
- Trial name
- NCT05644678
- Testing
- Fixed appliances, Corticotomy
- Where
- Syria
- Volunteers
- 46 people
- Sponsor
- Damascus University
Anterior Teeth Alignment Efficiency, Pain Perception
Comparison of Conventional and Cu-NiTi Archwires Regarding Clinical Efficiency and Pain Intensity Using Prostaglandin E2 Biomarker During Alignment and Leveling
Orthodontic treatment can inflame the periodontium and dental pulp, it can be uncomfortable and even painful at times. This may induce discomfort and the release of different biochemical mediators, which is one of the main causes…
- Conditions
- Anterior Teeth Alignment Efficiency, Pain Perception, PGE2 Biomarker and Their Correlation
- Trial name
- NCT06653881
- Testing
- ARCHWIRE
- Where
- India
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak
Adolescent Idiopathic Scoliosis
Long-Term Outcome Following the Treatment of Pediatric Scoliosis
Evaluate the long-term outcomes following operative and nonoperative treatment of childhood scoliosis.
- Trial name
- NCT01760434
- Testing
- Long-term outcomes
- Where
- United States
- Volunteers
- 66 people
- Sponsor
- Mayo Clinic
Sleep
Circadian Rhythms and Homeostatic Sleep Drive and Their Effect on Reward and Cognitive Control Systems in Adolescents
Adolescence is a time of heightened reward sensitivity and greater impulsivity. On top of this, many teenagers experience chronic sleep deprivation and misalignment of their circadian rhythms due to biological shifts in their…
- Trial name
- CARRS-P1 (NCT05336084)
- Testing
- Ultradian sleep/wake protocol
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Cervical Degenerative Disease
Improving Cervical Spine Alignment and Intervertebral Foramen Expansion Using a Novel Distally Expanding Cervical Facet Implant for Cervical Degenerative Disease
Cervical degenerative disease (CDD) resulting in myelopathy represents the commonest disease affecting the spinal cord in adults. Cervical radiculopathy can be associated with myelopathy or occurs alone.
- Trial name
- CeLFI (NCT07142174)
- Testing
- cervical facet implant will be introduced into the cervical levels that were mobile on flexion-extension x-ray and exhibited foramen stenosis or spondylolisthesis
- Where
- Saudi Arabia
- Volunteers
- 20 people
- Sponsor
- King Saud University
Pain
Comparison of Self-ligating and Conventional MBT Brackets Regarding Alignment Efficiency and Pain Perception
The rate of Orthodontic tooth movement affects the efficacy and time duration of the treatment. One of the key factors, during the initial alignment phase, is the amount of the force that the arch-wire applies to the dentition.
- Trial name
- NCT06895083
- Testing
- self ligating brackets
- Where
- Pakistan
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Shoaib Rahim
Crowding of Teeth
The Evaluation Of The Efficiency Of Micro-osteoperforation
Prolonged orthodontic treatment increases the risc of caries, periodontal problems and root resorption. Many different techniques were developed to shorten the treatment time.
- Trial name
- NCT03652454
- Testing
- micro-osteoperforation, conventional fixed appliance treatment
- Where
- Turkey (Türkiye)
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Izmir Katip Celebi University