Clinical trials: Alignment
Relapse
Effectiveness of Two Types of Fixed Lingual Retainers in Preventing Mandibular Incisor Relapse
The study evaluates effectiveness of two types of fixed retainers in post orthodontic patients. Half of the subjects are randomly allocated Group 1 retainer (FRC) and other half is given Group 2 retainer (MSW) and followed for a…
- Trial name
- NCT03881813
- Testing
- Orthodontic retainers
- Where
- Pakistan
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Dow University of Health Sciences
Congenital Medial Deviation
Three-Dimensional Hindfoot Alignment Measurements Based On Biplanar Radiographs: Prospective Clinical Feasibility Study
The measurement of hindfoot alignment is a technical challenge. Today, hindfoot alignment is typically measured on hindfoot alignment view radiographs or long axial view radiographs.
- Trial name
- NCT02196415
- Testing
- Biplanar Radiography
- Where
- Switzerland
- Volunteers
- 50 people
- Sponsor
- Balgrist University Hospital
Knee Osteoarthritis, Postoperative Rehabilitation
Paraspinal NMES and Spinopelvic Alignment After Knee Arthroplasty
Total knee arthroplasty (TKA) is a widely performed surgical procedure for patients with severe knee osteoarthritis. Following TKA, changes in lower extremity alignment and gait mechanics may influence the spinopelvic sagittal…
- Trial name
- NCT07741162
- Testing
- Standard Postoperative Rehabilitation Program, Quadriceps Neuromuscular Electrical Stimulation, Paraspinal Neuromuscular Electrical Stimulation
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Bursa Yuksek Ihtisas Training and Research Hospital
Aortic Valve Stenosis, Transcatheter Aortic Valve Replacement
COronary Re-engageMent aFter randOm NavitoR alignmenT (COMFORT STUDY)
Whereas PCI before TAVR was previously recommended despite its uncertain prognostic role, recent data underline the possibility of a postponed coronary intervention using a commissural alignment technique.
- Trial name
- COMFORT (NCT05779787)
- Testing
- TAVR Aligned, TAVR Random
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- Niguarda Hospital
Cataract Senile, Astigmatism
Accuracy of Topography Guided Automatic Marking of the Intraocular Lens (IOL) -Axis
In cataract surgery, the opaque lens is replaced by an artificial intraocular lens. The procedure also allows for correction of an refractive error such as myopia, hyperopia or astigmatism.
- Trial name
- NCT05750862
- Testing
- Marking of the intended axis of IOL-Implantation manually with an ink and marking device on the surface of the eye
- Where
- Switzerland
- Volunteers
- 30 people
- Sponsor
- Frank Bochmann
Non-secure Message Senders
eHealth Partnered Evaluation Initiative
On October 1, 2016, the VHA Office of Telehealth and the Connected Health Office will merge to create a single entity that will be responsible for the implementation and evaluation of eHealth technologies across the healthcare…
- Trial name
- eHealth PEI (NCT02665468)
- Testing
- Supported adoption intervention, Active comparator control
- Where
- 4 sites in United States
- Volunteers
- 1,196 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Primary Osteoarthritis of Knee Nos
A Prospective Study to Evaluate Robot Assisted Total Knee Replacement Outcomes
This study aims to see if outcomes for patients that receive the traditional total knee replacement surgical technique are different than the outcomes for patients that receive robot-assisted total knee replacement.
- Trial name
- NCT03523897
- Testing
- Robot Assisted Total Knee Replacement, Traditional Total Knee Replacement
- Where
- United States
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- Virtua Health, Inc.
Osteoarthritis
Minimally Invasive Total Knee Replacement - Navigated Versus Non-navigated Study
The primary objective of this investigation is to compare the precision of long leg alignment achieved by the two types of procedure.
- Trial name
- NCT00733330
- Testing
- Either P.F.C. Sigma or L.C.S. Complete knee replacement using the conventional surgical approach and manual surgical technique, Either P.F.C. Sigma or L.C.S. Complete knee replacement using minimally invasive surgical approach and computer navigation
- Where
- 5 sites in United States, Australia and 1 more
- Volunteers
- 86 people
- Sponsor
- DePuy International
Posture, Musculoskeletal Equilibrium
Acute Responses of Postural Alignment, Kinematic Synergy, and Intermuscular Coherence to Postural Muscle Facilitation (Retrospective)
Postural alignment is often intervened upon in health, fitness, and physical medicine settings. Despite a long tradition in this area, current notions of optimal or normal posture are superficial and often logically inconsistent.
- Trial name
- PPMvsRCM (NCT05912751)
- Testing
- Exercise Then Foam Roll, Foam Roll Then Exercise
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Radford University
Abdominal Aortic Aneurysm
Preferences for Open Vs. Endovascular Repair for Abdominal Aortic Aneurysm
This study tests the use of a decision aid for Veterans who are facing a decision about surgery for their Abdominal Aortic Aneurysm (AAA).
- Trial name
- PROVE-AAA (NCT03115346)
- Testing
- Decision aid
- Where
- 22 sites in United States
- Volunteers
- 241 people
- Sponsor
- VA Office of Research and Development
Knee Osteoarthritis
Trial Comparing Alignment Techniques - RSA of ATTUNE Knee System
The purpose of this study is to compare migration patterns between mechanical and anatomic alignment surgical techniques for the Attune S+ CR-FB knee system using model-based RSA over the first 2 post-operative years.
- Trial name
- NCT04079751
- Testing
- Neutral Mechanical Alignment, Anatomical Alignment
- Where
- 2 sites in Canada
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Canadian Radiostereometric Analysis Network
Total Knee Arthroplasty, Osteoarthritis
Kinematic and Mechanical Alignment Randomized Trial
Knee replacement surgery is the second most common surgery in Canada. People who have very painful knee arthritis usually receive a knee replacement where the surgeon aims to make everyone's knee as straight as possible (called…
- Trial name
- KMART (NCT06787417)
- Testing
- Restricted Kinematically-aligned Arthroplasty, Mechanically-Aligned Arthroplasty
- Where
- Canada
- Volunteers
- 260 people
- Sponsor
- McMaster University
Cervical Lordosis
Exploring Heart Rate Variability, EEG Pattern, and Corticomuscular Coherence After Cervical Sagittal Alignment Restoration
The goal of this Randomized clinical trial is to learn about how fixing neck curvature and head posture right away affects heart rate, brainwaves, and muscle coordination in college athletes.
- Trial name
- NCT06323746
- Testing
- Denneroll cervical traction orthodontic
- Where
- United Arab Emirates
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Sharjah
Cataract and IOL Surgery
HUD Surgical Guidance for Toric Alignment
This study aims to assess the accuracy of toric intraocular lens (IOL) alignment axes as calculated and displayed by a novel digital guidance system.
- Trial name
- CG-Toric (NCT07325188)
- Testing
- Cassini Guidance
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Gainesville Eye Associates
Malocclusion
A Comparison of the Alignment Achieved Using Computer-guided Indirect Bonding of Orthodontic Brackets to Conventional Appliance Placement
Technological advances have made computer aided orthodontic treatment planning possible. 3D dental scanners and software make it possible to design and approve the outcome before treatment begins.
- Trial name
- NCT02221856
- Testing
- Motion View, Conventional Orthodontic Treatment
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Harvard School of Dental Medicine
Osteoarthritis of the Knee
Total Knee Replacement Study Using Standard Cutting Guide vs Otismed MRI Generated Cutting Guide
Patients are referred to the VA orthopedic surgical clinic because of osteoarthritis and are requesting consideration for a total knee replacement. Those who qualify for the knee replacement are informed about the study.
- Trial name
- NCT00837772
- Testing
- Standard cutting guide for TKA, Otismed MRI generated cutting guide for TKA
- Where
- 2 sites in United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Phoenix VA Health Care System
Multiple Sclerosis, Balance
Spinal Alignment, Spinal Mobility, and Balance in Patients With Multiple Sclerosis
Multiple sclerosis (MS) is a chronic inflammatory autoimmune disease of the central nervous system characterized by demyelination and axonal degeneration.
- Trial name
- NCT07648277
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Ankara Yildirim Beyazıt University
Knee Arthroplasty, Total
Evaluation of Navigation-Assisted TKA Using Mechanical vs. Restricted Kinematic Alignment
The purpose of this study is to evaluate both clinical measures and PROMs in patients undergoing total knee arthroplasty (TKA) using restricted inverse kinematic alignment (iKA) compared to mechanical alignment (MA), both using…
- Trial name
- NCT05516381
- Testing
- Optetrak Logic CR Knee System
- Where
- Spain
- Volunteers
- 148 people, healthy volunteers welcome
- Sponsor
- Exactech
Critical Illness, Sleep Deprivation
Reestablishing Sleep and Circadian Alignment in Medical Intensive Care Unit (MICU) Patients Via a Mechanistic RCT of an Sleep Chronobundle
More than 5 million patients are admitted to the intensive care unit every year in the United States; most of these patients experience profound sleep and circadian disruption.
- Conditions
- Critical Illness, Sleep Deprivation, Circadian Rhythm Sleep Disorder, Unspecified
- Trial name
- ReAlign-ICU (NCT05551325)
- Testing
- Chronobundle - light, chronobundle - feeding, chronobundle - mobility
- Where
- 2 sites in United States
- Volunteers
- 160 people
- Sponsor
- Yale University
Cervical Spondylosis
Kinesthetic Exercises and Sine Sound Waves in Cervical Spondylosis
The goal of this Randomized control trial is to determine the Effect of kinesthetic exercises and sound waves on pain, ROM, shoulder alignment and disability in cervical spondylosis.
- Trial name
- NCT06351254
- Testing
- Sine sound waves, Kinesthetic exercises, Sine sound waves plus kinesthetic exercises
- Where
- Pakistan
- Volunteers
- 24 people
- Sponsor
- Riphah International University