Clinical trials: Alignment, active
Arthropathy, Knee Replacement
The Medacta GMK SpheriKA Post-Marketing Surveillance Study
This is a Post-Marketing Surveillance of GMK SpheriKA knee stem prosthesis.
- Trial name
- NCT05459948
- Testing
- GMK SpheriKA
- Where
- 4 sites in France, Italy and 1 more
- Volunteers
- 281 people
- Sponsor
- Medacta International SA
Vestibular Hypofunction, Binocular Vision Abnormalities
Visual Influences on Vestibular Adaptation
The goal of this study is to learn whether a balance-training exercise called incremental vestibulo-ocular reflex adaptation (IVA) is safe and effective for adults with vision impairments, with or without additional vestibular…
- Conditions
- Vestibular Hypofunction, Binocular Vision Abnormalities, Reduced Vision
- Trial name
- NCT07380256
- Testing
- StableEyes: Incremental Vestibulo-Ocular Reflex Adaptation (IVA)
- Where
- 2 sites in United States
- Volunteers
- 100 people
- Sponsor
- Emory University
Knee Osteoarthritis, Osteoarthritis (Knee)
Manual Arthroplasty Versus VELYS Robotic-Assisted Solution Functional Alignment Arthroplasty for Knee Osteoarthritis
The goal of this clinical trial is to learn if the VELYS Robotic-Assisted Solution (VRAS) device helps to improve outcomes from total knee replacement, when compared to regular non-robotic-assisted total knee replacement in the…
- Conditions
- Knee Osteoarthritis, Osteoarthritis (Knee), Osteo Arthritis of the Knee, Osteo Arthritis
- Trial name
- MARVEL Project (NCT07551856)
- Testing
- Robot-Assisted Functionally Aligned Total Knee Replacement, Manual Total Knee Arthroplasty
- Where
- United Kingdom
- Volunteers
- 346 people
- Sponsor
- Golden Jubilee National Hospital
Osteo Arthritis of the Knee, Genu Varum
Kinematic vs Mechanical Alignment in High Tibial Osteotomy
To compare between kinematic and mechanichal alignment after High Tibial Osteotomy (clinically and radiologically)
- Trial name
- NCT07551089
- Testing
- high tibial osteotomy
- Volunteers
- 100 people
- Sponsor
- Assiut University
Scoliosis Idiopathic Adolescent
Effect of a 16-Week Physiotherapeutic Corrective Exercise Program on Spinal Deformities in Adolescent Idiopathic Scoliosis
Brief Summary Adolescent idiopathic scoliosis (AIS) is a three-dimensional spinal deformity that may progress during adolescence and lead to postural asymmetry, spinal rotation, pelvic imbalance, reduced spinal mobility, and…
- Trial name
- SPINE-AIS16 (NCT07736456)
- Testing
- Structured Physiotherapeutic Corrective Exercise Program, Standard Physiotherapy Exercise Program
- Where
- Kosovo
- Volunteers
- 68 people
- Sponsor
- Alma Mater Europaea - Slovenia
Neuro-Ophthalmology
Safety and Normative Data With Neos™
The goal of this clinical study is to collect standard data for the medical device neos™. neos™ is a system that shows images and measures the resulting eye movements and pupil size. Collecting standard data involves three steps.
- Trial name
- neos-SNOW (NCT07258212)
- Where
- 3 sites in Switzerland
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- machineMD AG
Concussions
COmmunities Aligned to Reduce Concussion and Head Impact Exposure
Head impacts in collision sports such as football are a public health concern, as repetitive head impacts, even if a concussion is not suspected, have negative effects on brain health.
- Trial name
- COACH (NCT06624202)
- Testing
- COmmunities Aligned to reduce Concussion and Head impact exposure (COACH) Intervention
- Where
- United States
- Volunteers
- 880 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Exotropia, Exophoria
A-eyedrops on Ocular Alignment and Binocular Vision
Atropine is a non-selective muscarinic acetylcholine (M) receptor antagonist that paralyzes the ciliary muscle, dilates the pupil, and reduces the power of accommodation.
- Conditions
- Exotropia, Exophoria, Myopia
- Trial name
- NCT05379855
- Testing
- 0.01% atropine eye drops, 0.05% atropine eye drops
- Where
- China
- Volunteers
- 339 people
- Sponsor
- Eye & ENT Hospital of Fudan University
Soccer Players
Q-Angle, Segment Length, Quadriceps, and Knee Alignment in Soccer Players
The aim of this study is to investigate the relationship of Q-angle, lower extremity segment lengths, and quadriceps muscle activation with dynamic knee alignment during a single-leg squat in active soccer players.
- Trial name
- NCT07894250
- Testing
- Group 1
- Where
- Turkey (Türkiye)
- Volunteers
- 29 people
- Sponsor
- Suleyman Demirel University
Tooth Mobility, Injectable Platelet-rich Fibrin
Evaluating the Effect of Injectable Platelet-rich Fibrin on Accelerating Orthodontic Tooth Movement
One of the main goals of orthodontic treatment is the reduction of treatment time through faster tooth movement. The previous studies evaluating platelet-rich fibrin (PRF) and orthodontic tooth movement (OTM) are limited, which…
- Trial name
- NCT06302296
- Testing
- injectable form of PRF
- Where
- Syria
- Volunteers
- 14 people
- Sponsor
- Hama University
Knee Osteoarthritis
The personalKNEE Trial
Robotic knee surgery makes it possible to adopt different alignment philosophies in total knee arthroplasty. The classical operation where the knee is placed in a neutral manner, the so called mechanical alignment, has been used…
- Trial name
- NCT06507046
- Testing
- Total knee replacement
- Where
- Norway
- Volunteers
- 160 people
- Sponsor
- Helse Møre og Romsdal HF
Cervical Degenerative Disease
Improving Cervical Spine Alignment and Intervertebral Foramen Expansion Using a Novel Distally Expanding Cervical Facet Implant for Cervical Degenerative Disease
Cervical degenerative disease (CDD) resulting in myelopathy represents the commonest disease affecting the spinal cord in adults. Cervical radiculopathy can be associated with myelopathy or occurs alone.
- Trial name
- CeLFI (NCT07142174)
- Testing
- cervical facet implant will be introduced into the cervical levels that were mobile on flexion-extension x-ray and exhibited foramen stenosis or spondylolisthesis
- Where
- Saudi Arabia
- Volunteers
- 20 people
- Sponsor
- King Saud University
Patellofemoral Joint, Flatfoot
Effect of Foot Orthoses on Kneecap Position in Adults With Flexible Flatfoot
This study will look at whether correcting a flat foot position with foot orthoses, also called shoe inserts, can change the position of the kneecap during standing.
- Trial name
- NCT07678840
- Testing
- Foot Orthoses
- Where
- Denmark
- Volunteers
- 10 people
- Sponsor
- Regionshospital Nordjylland
Obesity (Disorder), Morbid Obesity
Chrono-ALIGN: A Chronotype-Based Chrono-Nutrition Intervention in Post-Bariatric Patients
This randomized controlled trial will evaluate the impact of chrono-nutrition, a dietary approach that aligns meal timing with the body's circadian rhythms, on weight change, metabolic outcomes, appetite, and gut microbiota in…
- Conditions
- Obesity (Disorder), Morbid Obesity, Bariatric Sleeve Gastrectomy, Meal Time
- Trial name
- Chrono-ALIGN (NCT07324044)
- Testing
- Standard Post-Bariatric Care (Control), Early Time-Restricted Eating (eTRE), Chronotype-Based Chrono-Nutrition (CB-CN)
- Where
- Saudi Arabia
- Volunteers
- 246 people, healthy volunteers welcome
- Sponsor
- King Saud University
Knee Osteoarthritis
Prospective Randomized Study Comparing the SpheriKA® (MEDACTA) and Origin® (SYMBIOS) Prostheses During Total Knee Replacement Using the Kinematic Alignment Technique
The traditional technique for implanting a total knee prosthesis, known as mechanical alignment, does not aim to preserve the original anatomy and laxity of the knee.
- Trial name
- KAOR (NCT06603103)
- Testing
- SPHERIKA prosthesis, ORIGIN prosthesis
- Where
- France
- Volunteers
- 120 people
- Sponsor
- Clinique du Sport, Bordeaux Mérignac
Thoracic Hyperkyphosis
Kinesio Taping in Young Adults With Thoracic Hyperkyphosis
Thoracic hyperkyphosis is a postural disorder characterized by excessive thoracic curvature exceeding 40°, which may negatively affect proprioception, postural alignment, and muscle mechanical properties.
- Trial name
- NCT07888790
- Testing
- Kinesiology Taping
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Istinye University
Osteo Arthritis Knee
Traditional Versus Alternative Alignment in TKR
As many as 20% of patients are unhappy with the results of total knee replacement (TKR). Various changes to surgical technique have tried to address this but have not led to a significant improvement in the numbers of patients…
- Trial name
- NCT03196011
- Testing
- TKR with mechanical alignment method, TKR with alternative alignment method
- Where
- United Kingdom
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Royal Devon and Exeter NHS Foundation Trust
Smoking Cessation
American Indian Smokefree Native RCT
The aim of this clinical trial is to test the efficacy of a culturally aligned digital smoking cessation resource for American Indian persons who smoke, via a remotely conducted randomized controlled trial.
- Trial name
- NCT06544811
- Testing
- Smoking Cessation Program, Cultural Smoking Cessation Program
- Where
- United States
- Volunteers
- 416 people, healthy volunteers welcome
- Sponsor
- Masonic Cancer Center, University of Minnesota
Effectiveness of the I-arch System
Clinical Performance of the I-arch System During the Initial Stage of Orthodontic Treatment
The goal of this clinical trial is to learn if the I-arch system works to align the moderately misaligned teeth in patients seeking orthodontic treatment.
- Trial name
- NCT07264127
- Testing
- The use of 0.016×0.014 copper nickel titanium arch wire during the alignment stage., Use of 0.014- then 0.016-inch heat-activated nickel titanium arch wire during the alignment stage.
- Where
- Iraq
- Volunteers
- 34 people
- Sponsor
- Tabark H. Omran
Cataract and IOL Surgery
HUD Surgical Guidance for Toric Alignment
This study aims to assess the accuracy of toric intraocular lens (IOL) alignment axes as calculated and displayed by a novel digital guidance system.
- Trial name
- CG-Toric (NCT07325188)
- Testing
- Cassini Guidance
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Gainesville Eye Associates