Clinical trials: All Surgery, open to volunteers
Clear Cell Renal Cell Carcinoma, Renal Cell Carcinoma (RCC)
Testing the Addition of the Anti-Cancer Drug Tivozanib to Immunotherapy (Pembrolizumab) After Surgery to Remove All Known Sites of Kidney Cancer
This phase III trial compares the effect of adding tivozanib to standard therapy pembrolizumab versus pembrolizumab alone for the treatment of patients with high-risk renal cell carcinoma (RCC).
- Conditions
- Clear Cell Renal Cell Carcinoma, Renal Cell Carcinoma (RCC), Stage II Renal Pelvis Cancer AJCC v8, Stage III Renal Pelvis Cancer AJCC v8
- Trial name
- STRIKE (NCT06661720)
- Testing
- Pembrolizumab, Tivozanib, Biospecimen Collection
- Where
- 425 sites in United States
- Volunteers
- 1,040 people
- Sponsor
- Alliance for Clinical Trials in Oncology
Anesthesia Recovery
OS Anesthesia Followup of All Bariatric Procedures at One Hospital
Database registering demographic patient data, anesthesia and surgery information, post operative recovery and complications if any.
- Trial name
- NCT03200964
- Testing
- anesthesia given as required for surgical procedure
- Where
- Belgium
- Volunteers
- 20,000 people
- Sponsor
- AZ Sint-Jan AV
Surgical Site Infection
Novosyn® CHD vs Polyglactin 910 Suture to Close Wounds After Emergency or Elective Laparotomy or Laparoscopic Surgery
The aim of the study is to elucidate, if the colonization of bacteria is lower on the Novosyn® CHD suture compared to uncoated Polyglactin 910 suture, which will be assessed by the incidence of surgical site infections (SSI: A1…
- Trial name
- POLYNOVO-CHD (NCT05966961)
- Testing
- Novosyn® in emergency or elective laparotomy or laparoscopic surgery, Polyglactin 910 in emergency or elective laparotomy or laparoscopic surgery
- Where
- 4 sites in Italy, Spain
- Volunteers
- 2,998 people
- Sponsor
- Aesculap AG
Anesthesia
Efficacy, Safety and Limitations of Spinal Block for All Infants Under 3 Months
Spinal anesthesia (SA) has been shown to be a viable alternative to general anesthesia (GA) for infants and children for a variety of surgical procedures.
- Trial name
- NCT06871995
- Testing
- spinal block
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Ain Shams University
Microvascular Obstruction (MVO), Multivessel Coronary Artery Disease
For Patients With Myocardial Infarction and Multiple Vessel: Testing if Ultrasound (UFR) Can Guide All Needed Treatment in One Procedure, Avoiding a Return Hospital Visit for a Second Operation.
Brief Summary The Purpose of the Study : The purpose of this study is to find a safe and reliable "one-stop" solution for treating heart attack patients who have multiple blocked arteries.
- Conditions
- Microvascular Obstruction (MVO), Multivessel Coronary Artery Disease, ACS (Acute Coronary Syndrome), ST Elevation Myocardial Infarction (STEMI)
- Trial name
- ACT-EVOLVE (NCT07264881)
- Testing
- IVUS-based Fractional Flow Reserve (UFR), Invasive Coronary Physiology Measurement (FFR/RFR/IMR), Cardiac Magnetic Resonance (CMR)
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Beijing Anzhen Hospital
Emergency Gastrointestinal Surgery, Mortality Within 30 Days
Construction and Validation of a Prediction Model for All - Cause Mortality Within 30 Days After Surgery in Critically Ill Patients Undergoing Emergency Gastrointestinal Surgery
Gastrointestinal surgeries are crucial for treating digestive tract diseases. However, they often lead to high postoperative infection rates due to long durations, bacterial translocation, weakened immunity, and reduced…
- Trial name
- EGS-30MP (NCT06787157)
- Testing
- Prediction Model Construction
- Volunteers
- 900 people
- Sponsor
- Quan Wang
Pancreatic Cancer, Surgery
Pancreatic Cancer and Diabetes Mellitus
The goal of this observational study is to learn about post-surgery of pancreatic cancer diabetes mellitus.The main questions it aims to answer are: 1.
- Conditions
- Pancreatic Cancer, Surgery, Diabetes Mellitus
- Trial name
- NCT06585072
- Testing
- All enrolled subjects completed dynamic blood glucose monitoring to obtain continuous peripheral blood glucose data.
- Where
- China
- Volunteers
- 150 people
- Sponsor
- Shanghai Changzheng Hospital
Bone Loss
All-on-X Stackable Guides for Maxillary Terminal Dentition
This retrospective study will evaluate the clinical performance of maxillary All-on-X(full-arch implant-supported rehabilitation) implant rehabilitation using stackable guided surgery and immediate loading.
- Trial name
- NCT07353619
- Testing
- Maxillary All-on-X implant rehabilitation using a fully digital stackable guided surgery workflow with immediate loading.
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Menoufia University