Clinical trials: Allergic
Allergic Rhinitis, Sinusitis
Harnessing Digital Medicine to Improve Allergic Rhinitis Management in Primary Care (DMAR)
This study aims to evaluate the effectiveness of digital tools in managing allergic rhinitis (AR) in primary care settings. AR is a common condition that affects many people's quality of life.
- Trial name
- DMAR (NCT06603935)
- Testing
- QHSLab Digital Tools (AME and ARIS)
- Where
- United States
- Volunteers
- 240 people
- Sponsor
- QHSLab, Inc.
Allergy
Safety and Efficacy of Sublingual Immunotherapy (SLIT) Tablets in Grass Pollen Rhinoconjunctivitis
To evaluate the safety and efficacy of SLIT compared with placebo for reduction of symptoms and rescue medication usage
- Trial name
- NCT00367640
- Testing
- 100 IR grass pollen allergen extract tablet, 300 IR grass pollen allergen extract tablet, 500 IR grass pollen allergen extract tablet
- Volunteers
- 628 people
- Sponsor
- Stallergenes Greer
Allergic Rhinitis
Single Dose Crossover Study of Patient Preference for Unscented Nasonex® Nasal Spray Versus Scented Flonase® Nasal Spray (Study P04207)
This was a one-day single dose trial conducted to compare patient's preference for Nasonex® (mometasone) versus Flonase® nasal spray. Each patient was randomized to take one dose (2 sprays in each nostril) of Nasonex or Flonase.
- Trial name
- NCT00817050
- Testing
- Mometasone Furoate Nasal Spray, fluticasone nasal spray
- Volunteers
- 100 people
- Sponsor
- Organon and Co
Seasonal Allergic Rhinitis, Hay Fever
PK/PD and Steady State Efficacy Study of Bilastine Compared With Placebo Given Orally in the Treatment of the Symptoms of SAR in an EEC Model (5-arm)
The purpose of this study is to evaluate the relative efficacy of four dosing regimens of bilastine tablets versus placebo in subjects with SAR exposed in controlled ragweed pollen using the EEC model based on the mean change…
- Conditions
- Seasonal Allergic Rhinitis, Hay Fever, Rhinoconjunctivitis
- Trial name
- NCT00574210
- Testing
- Bilastine
- Where
- Canada
- Volunteers
- 502 people
- Sponsor
- Faes Farma, S.A.
Rhinitis Allergic
A Study Assessing the Safety and Effectiveness of FEX60/PE10 Fixed Combination Tablet in Patients With Allergic Rhinitis
Primary Objective: To assess the safety of twice-daily fexofenadine 60 mg/phenylephrine 10 mg (FEX60/PE10) combination tablet in patients with allergic rhinitis.
- Trial name
- NCT02401191
- Testing
- FEX60/PE10
- Where
- Japan
- Volunteers
- 105 people
- Sponsor
- Sanofi
Seasonal Allergic Rhinitis
Study to Compare the Pharmacokinetics of Fixed-Dose Combination of Mometasone + Azelastine Nasal Spray to Mometasone and Azelastine Nasal Sprays in Adolescents and Young Adults With Seasonal Allergic Rhinitis
This study will compare the PK parameters of the combination test formulation to monotherapy reference products (mometasone furoate and azelastine hydrochloride) in adolescents and young adult patients with seasonal allergic…
- Trial name
- NCT05887843
- Testing
- Mometasone + Azelastine, Mometasone Furoate, Azelastine Hydrochloride
- Where
- Canada
- Volunteers
- 38 people
- Sponsor
- Sandoz
Rhinitis, Allergic, Perennial
A Study of GW685698X for the Treatment Of Perennial Allergic Rhinitis in Adolescents and Adults
The purpose of this study is to assess the effect of an aqueous nasal spray investigational compound compared to placebo on the hypothalamic pituitary adrenocortical (HPA) axis system in adolescents and adults 12 to 65 years of…
- Trial name
- NCT00116818
- Testing
- GW685698X aqueous nasal spray
- Where
- 2 sites in United States, Canada
- Volunteers
- 90 people
- Sponsor
- GlaxoSmithKline
Diphtheria, Acellular Pertussis
Impact of Boostrix™ Maternal Vaccination on Morbidity and Mortality of Pertussis Disease in Infants ≤6 Weeks of Age, in Bogota, Colombia.
This study is being conducted to assess impact of maternal immunisation against pertussis in infants ≤12 months of age before and after introduction of pertussis maternal immunisation in Bogota, Colombia from January…
- Conditions
- Diphtheria, Acellular Pertussis, Tetanus, Aspergillosis, Allergic Bronchopulmonary
- Trial name
- NCT02569879
- Testing
- Pertussis maternal immunization
- Where
- Colombia
- Volunteers
- 1 people
- Sponsor
- GlaxoSmithKline
Rhinitis, Allergic
Exploratory Study for Allergy Relief Onset
The purpose of the study is to explore the onset of effect of an antihistamine in a controlled environment.
- Trial name
- NCT02722083
- Testing
- Chlorpheniramine maleate (BAY X002134)
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Bayer
Invasive Pulmonary Aspergillosis, Allergic Bronchopulmonary Aspergillosis
Voriconazole Inhalation Powder for the Treatment of Pulmonary Aspergillosis
Voriconazole Inhalation Powder is available on an expanded access basis to patients with pulmonary aspergillosis for up to 12 weeks.
- Conditions
- Invasive Pulmonary Aspergillosis, Allergic Bronchopulmonary Aspergillosis, Chronic Pulmonary Aspergillosis, Aspergillus Tracheobronchitis
- Trial name
- NCT05897294
- Testing
- Voriconazole Inhalation Powder
- Sponsor
- TFF Pharmaceuticals, Inc.
Allergic Rhinitis
Study Evaluating Nasal Symptoms Induced by a Nasal Allergen Challenge (NAC) To House Dust Mite Allergen
A Multi-Center Study Evaluating the Nasal Allergic Symptomatology Induced by a Nasal Allergen Challenge (NAC) in a Dust Mite Population
- Trial name
- NCT01936818
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- ORA, Inc.
Dermatitis
Efficacy and Safety of the Association Drugs in Patients With Allergic Dermatitis
Considering the pathogenesis of several allergic skin diseases to be investigated in this study as well as the pharmacodynamic mechanisms of the association of dexamethasone and clemastine fumarate, it is believed that the…
- Trial name
- NCT01125761
- Testing
- dexamethasone 0.5 mg and 1.0 mg clemastine cream, Dexamethasone 0,5 mg cream
- Where
- 2 sites in Brazil
- Sponsor
- Azidus Brasil
Conjunctivitis Allergic
A Study to Identify and Characterize Adults and Pediatric Participants With Cat and/or Birch Allergy
The purpose of this Patient Identification and Characterization (PIC) study is to collect information and perform limited allergy-related procedures to determine if participants can qualify for cat and/or birch tree pollen…
- Trial name
- NCT07710846
- Testing
- Noninterventional
- Volunteers
- 1,500 people
- Sponsor
- Regeneron Pharmaceuticals
Bronchial Asthma
OC000459 Bronchial Allergen Challenge
OC0000459 reduces inflammation in the tissues in response to allergic stimuli in patients with asthma. This clinical trial, in mildly asthmatic patients, studies the effects of OC000459 and placebo on the asthmatic response to…
- Trial name
- NCT01056692
- Testing
- OC000459
- Where
- 2 sites in United Kingdom
- Volunteers
- 20 people
- Sponsor
- Oxagen Ltd
Seasonal Allergic Rhinitis
Efficacy and Safety of SPARC1310 in Seasonal Allergic Rhinitis
The study will assess the efficacy and safety of SPARC1310 when compared to placebo and active control
- Trial name
- NCT01940146
- Testing
- SPARC1310 I, SPARC1310 II, SPARC1310 III
- Where
- Canada
- Volunteers
- 222 people
- Sponsor
- Sun Pharma Advanced Research Company Limited
Allergic Rhinoconjunctivitis
Clinical Trial With Subcutaneous Immunotherapy in Depot Presentation in Patients With Allergic Rhinoconjunctivitis Sensitized to House Dust Mites
The aim of the study is to evaluate the safety and tolerability of subcutaneous immunotherapy (SCIT) with House Dust Mite (HDM) extract in patients with rhinoconjunctivitis with or without associated mild asthma and sensitized to…
- Trial name
- NCT02881879
- Testing
- Allergovac depot DPT/DF (50:50)
- Where
- 5 sites in Spain
- Volunteers
- 43 people
- Sponsor
- Roxall Medicina España S.A
Nasal Obstruction, Sneezing
Demonstrate the Therapeutic Clinical Equivalence of Two Mometasone Nasal Sprays
Demonstrate the therapeutic clinical equivalence of two mometasone nasal sprays in the relief of the signs and symptoms of perennial allergic rhinitis, in term of changes at week 8 from baseline of Total Nasal Symptom Scores…
- Conditions
- Nasal Obstruction, Sneezing, Itching
- Trial name
- PHT-01-12 (NCT01702103)
- Testing
- Mometasone furoate
- Where
- Argentina
- Volunteers
- 360 people
- Sponsor
- PH&T S.p.A.
Perennial Allergic Rhinitis
A 6 Month Study of Once Daily Ciclesonide Hydrofluoroalkane (HFA) Nasal Aerosol in The Treatment of Perennial Allergic Rhinitis (PAR) in Subjects 12 Years and Older
6-month safety extension study in subjects who have completed Study 060-633 (NCT00953147). Evaluating the long-term safety of ciclesonide HFA nasal aerosol 160 μg administered once-daily in patients with Perennial Allergic…
- Trial name
- NCT01067105
- Testing
- ciclesonide HFA 160 μg
- Where
- 44 sites in United States
- Volunteers
- 824 people
- Sponsor
- Sumitomo Pharma America, Inc.
Allergic Rhinoconjunctivitis
Conjunctival Allergen Challenge (CAC) Following Allergen Exposure in the Allergen BioCube (ABC)
To evaluate the effect of Conjunctival Allergen Challenge (CAC) with Dust Mites on nasal and ocular allergic symptoms following allergen exposure in the Allergen BioCube (ABC).
- Trial name
- ABC CAC (NCT00985296)
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- ORA, Inc.
Perennial Allergic Rhinitis Accompanied by Asthma
Study to Evaluate the Efficacy and Safety of DW1807 in Perennial Allergic Rhinitis Patients With Asthma
This study aims to compare the efficacy and safety of DW1807 and DW1807-R2 in patients with perennial allergic rhinitis and comorbid asthma.
- Trial name
- NCT07168473
- Testing
- Experimental, Comparator
- Where
- South Korea
- Volunteers
- 274 people
- Sponsor
- Daewon Pharmaceutical Co., Ltd.