Clinical trials: Allergic Disease
Allergy
Efficacy and Safety of Subcutaneous Immunotherapy in Birch Pollen Allergic Patients
To compare versus placebo the efficacy and safety of recombinant Bet v1, natural purified Bet v1 and birch pollen licenced extract used for subcutaneous immunotherapy.
- Trial name
- NCT00410930
- Testing
- Subcutaneous immunotherapy - Recombinant birch pollen
- Where
- France
- Volunteers
- 160 people
- Sponsor
- Stallergenes Greer
Allergic Conjunctivitis
Evaluation of TL-925 for the Treatment of Allergic Conjunctivitis
In this prospective, Phase 2, randomized, double-masked, vehicle controlled study, approximately 66 eligible subjects will be randomized 1:1 to receive either TL-925 or placebo as topical ophthalmic eye drops administered…
- Trial name
- NCT06686472
- Testing
- TL-925
- Where
- United States
- Volunteers
- 66 people
- Sponsor
- Telios Pharma, Inc.
Rhinitis, Allergic, Seasonal, Hay Fever
A Study of Ciclesonide Nasal Spray in Patients 18 Years and Older With Seasonal Allergic Rhinitis (BY9010/M1-413)
The purpose of this study is to investigate the safety and effectiveness of ciclesonide nasal spray as compared with placebo (inactive substance) nasal spray in relieving symptoms of seasonal allergic rhinitis caused by pollen.
- Trial name
- NCT00384475
- Testing
- Ciclesonide Nasal Spray
- Where
- Canada
- Volunteers
- 500 people
- Sponsor
- AstraZeneca
Asthma
XOLAIR (Omalizumab) Outcomes in Pediatric Allergic Asthma Patients in the United States
A retrospective database pre-post cohort study, identifying asthmatic patients, aged 6- 11, with omalizumab use over 24 months
- Trial name
- NCT05157087
- Testing
- Omalizumab
- Where
- United States
- Volunteers
- 16,246 people
- Sponsor
- Novartis Pharmaceuticals
Alveolitis Extrinsic Allergic, Pulmonary Fibrosis
Pirfenidone in the Chronic Hypersensitivity Pneumonitis Treatment
The Chronic Hypersensitivity Pneumonitis (HP), is an inflammatory disease who has an evolution to develop progressive interstitial fibrosis, who cause the death of the patient.
- Trial name
- Picheon (NCT02496182)
- Testing
- Pirfenidone
- Where
- Mexico
- Volunteers
- 60 people
- Sponsor
- Grupo Medifarma, S. A. de C. V.
Allergy
Pilot Study: Characterization of the Immune Phenotype of Patients Allergic to Wasp Venom or Penicillin
Severity of allergic reactions are highly variable from one individual to another, they can range from absent to life threatening.
- Trial name
- WasPenIP (NCT03219827)
- Testing
- Human biological samples
- Where
- 2 sites in France
- Volunteers
- 10 people
- Sponsor
- Institut Pasteur
Allergic Rhinitis
Study of Nasonex in the Relief of Nasal Congestion in Patients With Seasonal Allergic Rhinitis (Study P05528)(COMPLETED)
This study seeks to prospectively demonstrate that Nasonex is better than placebo in relieving nasal congestion in patients with seasonal allergic rhinitis.
- Trial name
- NCT00733005
- Testing
- Mometasone furoate nasal spray (MFNS)
- Volunteers
- 324 people
- Sponsor
- Organon and Co
Perennial Allergic Rhinitis
A 6 Month Study of Once Daily Ciclesonide Hydrofluoroalkane (HFA) Nasal Aerosol in The Treatment of Perennial Allergic Rhinitis (PAR) in Subjects 12 Years and Older
6-month safety extension study in subjects who have completed Study 060-633 (NCT00953147). Evaluating the long-term safety of ciclesonide HFA nasal aerosol 160 μg administered once-daily in patients with Perennial Allergic…
- Trial name
- NCT01067105
- Testing
- ciclesonide HFA 160 μg
- Where
- 44 sites in United States
- Volunteers
- 824 people
- Sponsor
- Sumitomo Pharma America, Inc.
Rhinitis, Allergic, Seasonal
Efficacy of Levocetirizine and Cetirizine in Reducing Symptoms of Seasonal Allergic Rhinitis in Ragweed Sensitive Subjects
Controlled conditions of the EEU allow a reliable assessment of the efficacy and a determination of the action onset, action intensity and duration of effect of levocetirizine and cetirizine in order to establish the relative…
- Trial name
- NCT00544388
- Testing
- levocetirizine dihydrochloride
- Volunteers
- 570 people
- Sponsor
- UCB Pharma
Allergic Rhinitis
Fexofenadine (Allegra®) in Healthy Adults Who Have Been Identified as Slow Metabolizers for Desloratadine
To evaluate the single-dose and steady-state pharmacokinetics of desloratadine and fexofenadine in desloratadine slow metabolizers.
- Trial name
- NCT00636870
- Testing
- Fexofenadine
- Where
- United States
- Volunteers
- 220 people
- Sponsor
- Sanofi
Peanut Allergy
A Study to Evaluate Safety, Tolerability and Immune Response in Adults Allergic to Peanut After Receiving Intradermal or Intramuscular Administration of ASP0892 (ARA-LAMP-vax), a Single Multivalent Peanut (Ara h1, h2, h3) Lysosomal Associated Membrane Protein DNA Plasmid Vaccine
The purpose of this study is to evaluate the safety and tolerability of ASP0892 after intradermal or intramuscular injection in adults with peanut allergy.
- Trial name
- NCT02851277
- Testing
- ASP0892 Intradermal, ASP0892 Intramuscular
- Where
- 8 sites in United States
- Volunteers
- 31 people
- Sponsor
- Astellas Pharma Global Development, Inc.
Seasonal Allergic Rhinitis
A Clinical Study on the Efficacy, Safety, Pharmacokinetics and Pharmacodynamics of SHR-1819 Injection in Patients With Seasonal Allergic Rhinitis
This is a trial to evaluate the safety and efficacy of SHR-1819 injection in the treatment of patients with seasonal allergic rhinitis.
- Trial name
- NCT07091357
- Testing
- SHR-1819 Injection
- Where
- China
- Volunteers
- 108 people
- Sponsor
- Guangdong Hengrui Pharmaceutical Co., Ltd
Seasonal Allergic Rhinitis
Bepotastine Besilate Nasal Sprays in the Treatment of Seasonal Allergic Rhinitis (SAR)
This study will examine dose ranging characteristics of bepotastine besilate nasal spray compared to placebo nasal spray in 600 male or female subjects 12 years of age and older with active seasonal allergic rhinitis (SAR) and a…
- Trial name
- NCT01753739
- Testing
- Bepotastine besilate
- Where
- United States
- Volunteers
- 617 people
- Sponsor
- Bausch & Lomb Incorporated
Conjunctivitis, Allergic
Evaluation of the Onset and Duration of Action of Bepotastine Besilate Ophthalmic Solution in Acute Allergic Conjunctivitis
The purpose of this study is to evaluate whether bepotastine besilate ophthalmic solution is effective in the treatment of acute allergic conjunctivitis
- Trial name
- NCT00424398
- Testing
- Bepreve, Bepotastine Besilate
- Where
- United States
- Volunteers
- 107 people
- Sponsor
- Bausch & Lomb Incorporated
Seasonal Allergic Rhinitis, Hay Fever
PK/PD and Steady State Efficacy Study of Bilastine Compared With Placebo Given Orally in the Treatment of the Symptoms of SAR in an EEC Model (5-arm)
The purpose of this study is to evaluate the relative efficacy of four dosing regimens of bilastine tablets versus placebo in subjects with SAR exposed in controlled ragweed pollen using the EEC model based on the mean change…
- Conditions
- Seasonal Allergic Rhinitis, Hay Fever, Rhinoconjunctivitis
- Trial name
- NCT00574210
- Testing
- Bilastine
- Where
- Canada
- Volunteers
- 502 people
- Sponsor
- Faes Farma, S.A.
Seasonal Allergic Rhinitis
Study of Mometasone Furoate Nasal Spray and Oxymetazoline Nasal Spray Given Together Once A Day To Treat Seasonal Allergic Rhinitis (P04500)
The primary objective of this study is to evaluate the efficacy of the combination of mometasone furoate nasal spray (MFNS) and oxymetazoline nasal spray (OXY) given together once a day in treating subjects with seasonal allergic…
- Trial name
- NCT00552110
- Testing
- OXY combination: mometasone furoate nasal spray (MFNS) and oxymetazoline nasal spray (OXY), mometasone furoate nasal spray (MFNS) once daily, oxymetazoline nasal spray (OXY) twice daily
- Volunteers
- 707 people
- Sponsor
- Organon and Co
Seasonal Allergic Rhinitis
A Study to Evaluate the Safety and Effectiveness of a Nasal Spray to Treat Seasonal Allergies
The purpose of this study is to determine if two allergy medications (azelastine and fluticasone) are more effective than placebo or either medication alone (azelastine or fluticasone)
- Trial name
- NCT00651118
- Testing
- azelastine Hcl, azelastineHcl / fluticasone propionate, fluticasone propionate
- Where
- 43 sites in United States
- Volunteers
- 832 people
- Sponsor
- Meda Pharmaceuticals
Seasonal Allergic Rhinitis
Effect of a Nasal Bolus Allergen Challenge on Inflammatory Markers
The current study will investigate nasal inflammatory markers obtained by filter paper collection techniques, in subjects with allergic rhinitis, determining the most appropriate time points and handling conditions, prior to…
- Trial name
- NCT00483353
- Testing
- Intra-nasal allergen challenge with Phleum pratense., Collection of nasal effluent using filter paper., Measurement of nasal congestion using acoustic rhinometry.
- Where
- United Kingdom
- Volunteers
- 6 people
- Sponsor
- Pfizer
Seasonal Allergic Rhinitis
Proof of Activity Study of UR-63325 in Allergic Rhinitis Induced by Nasal Challenge
The purpose of this study is to explore the activity of UR-63325 in a model of allergic rhinitis induced by nasal allergen challenge to known allergic rhinitis patients otherwise healthy.
- Trial name
- NCT01260753
- Testing
- UR-63325, Fluticasone propionate nasal spray
- Where
- Germany
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Palau Pharma S.L.U.
Perennial Allergic Rhinitis, Allergic Rhinitis
Safety and Effectiveness of Ciclesonide Nasal Spray in Patients With Perennial Allergic Rhinitis During One Year Treatment (BY9010/M1-404)
The purpose of this study is to investigate the safety and effectiveness of ciclesonide nasal spray as compared with placebo (inactive substance) nasal spray in relieving symptoms of perennial allergic rhinitis.
- Conditions
- Perennial Allergic Rhinitis, Allergic Rhinitis, Hay Fever
- Trial name
- NCT00163501
- Testing
- Ciclesonide
- Where
- 41 sites in United States
- Volunteers
- 600 people
- Sponsor
- AstraZeneca
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