Clinical trials: Allergic Disease
Rhinitis, Allergic, Perennial, Allergic Rhinitis
A Randomised, Double Blind, Placebo Controlled, 4 Period, Incomplete Block, Crossover Study Assessing the Dose-response Curve of Fluticasone Propionate in an Antigen Challenge Chamber
This is a single-centre, randomised, double-blind, four-period, incomplete block, crossover study, with 8 days repeat dosing of intranasal Fluticasone Propionate (25, 50, 100, 200ug) and/or placebo in the Vienna Challenge Chamber…
- Trial name
- NCT00848965
- Testing
- Fluticasone propionate
- Where
- Austria
- Volunteers
- 59 people
- Sponsor
- GlaxoSmithKline
Allergic Rhinitis
Study for the Treatment of Persistent Allergic Rhinitis With Desloratadine (Study P04684)
This study will investigate the effectiveness of desloratadine in treating subjects with allergic rhinitis who meet the criteria for persistent allergic rhinitis (PER)
- Trial name
- NCT00405964
- Testing
- 5-mg Desloratadine
- Volunteers
- 716 people
- Sponsor
- Organon and Co
Asthma
Efficacy and Safety Trial of the ALK HDM Tablet in House Dust Mite Allergic Subjects
The purpose of the trial is to determine if treatment of asthma patients allergic to house dust mites with the ALK HDM tablet can reduce the need of inhaled corticosteroids (ICS).
- Trial name
- NCT00389363
- Testing
- ALK HDM tablet
- Where
- Denmark
- Volunteers
- 800 people
- Sponsor
- ALK-Abelló A/S
Allergy, Peanut
Safety and Efficacy Study of Viaskin Peanut in Peanut-allergic Children 4-7 Years of Age
The primary purpose of this study is to assess the efficacy and safety of daily DBV712 250 micrograms (mcg) to induce desensitization to peanut in peanut-allergic children 4-7 years of age over a 12-month double-blind…
- Trial name
- VITESSE (NCT05741476)
- Testing
- DBV712
- Where
- 87 sites in United States, Australia and 7 more
- Volunteers
- 600 people
- Sponsor
- DBV Technologies
Perennial Allergic Rhinitis
Safety of PATANASE Nasal Spray in Patients With Perennial Allergic Rhinitis
The purpose of this study was to assess local nasal adverse effects, as well as systemic effects, of PATANASE nasal spray when compared with Patanase Vehicle, pH 3.7 and Patanase Vehicle, pH 7.0 in patients with perennial…
- Trial name
- NCT00789555
- Testing
- Olopatadine hydrochloride 0.6% nasal spray (PATANASE), Olopatadine nasal spray vehicle, pH 3.7, Olopatadine nasal spray vehicle, pH 7.0
- Where
- United States
- Volunteers
- 1,260 people
- Sponsor
- Alcon Research
Allergic Rhinitis
Taste Test Between Desloratadine and Cetirizine Syrup in Children (Study P03829)(COMPLETED)
This study was conducted to compare the taste acceptability of Zyrtec syrup with desloratadine syrup in children. Children between 6 and 11 years of age received 5 mL of each syrup, separated by 15 to 20 minutes on a single day.
- Trial name
- NCT00794378
- Testing
- Desloratadine (Clarinex), Cetirizine (Zyrtec)
- Volunteers
- 202 people
- Sponsor
- Organon and Co
Rhinitis, Allergic, Seasonal
Study of Nasal Symptom Relief and Side Effects in Hayfever Patients Treated With Aerius (Desloratadine)(P03442)
The purpose of this study was to test the effectiveness and side effects of desloratadine (Aerius) in patients with hayfever. Patients took desloratadine once a day for 15 days.
- Trial name
- NCT00805584
- Testing
- desloratadine
- Volunteers
- 311 people
- Sponsor
- Organon and Co
Allergic Conjunctivitis
A Single-Center,Evaluation of the Onset and Duration of Action of AC-170 0.24% Compared to Vehicle
The purpose of this study is to evaluate the onset and duration of action of AC-170 0.24% compared to vehicle in the prevention of the signs and symptoms of allergic conjunctivitis in the conjunctival allergen challenge (CAC)…
- Trial name
- NCT01685242
- Testing
- AC-170 0.24%, AC-170 0%
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Aciex Therapeutics, Inc.
Seasonal Allergic Rhinitis
Clinical Equivalence of Azelastine Hydrochloride and Fluticasone Propionate, 137/50 mcg Nasal Spray to Dymista™
To evaluate the therapeutic equivalence of a test formulation of Azelastine hydrochloride and Fluticasone propionate Nasal Spray to the reference listed drug, Dymista™ Nasal Spray in the relief of the signs and symptoms of…
- Trial name
- NCT02249663
- Testing
- Azelastine hydrochloride and Fluticasone propionate, Dymista™
- Where
- United States
- Volunteers
- 1,535 people
- Sponsor
- Teva Pharmaceuticals USA
Seasonal Allergic Rhinitis
POPULAR (Preference Of Patient Using Levocetirizine in Allergic Rhinitis)
Comparative study on clinical efficacy and safety of levocetirizine and desloratadine as measured by the subject's satisfaction/dissatisfaction after one week of treatment
- Trial name
- NCT00160537
- Testing
- Levocetirizine
- Volunteers
- 200 people
- Sponsor
- UCB Pharma
Seasonal Allergic Rhinitis, Sinusitis
A Study To Investigate If MRI Scanning Is Effective At Seeing What Hayfever Drugs Do In Nasal Passage.
The purpose of this study is to establish whether MRI scanning is a sensitive measure of the effects of existing drug treatments on nasal dimensions following challenge with intranasal allergen in subjects with hayfever.
- Trial name
- NCT00517946
- Testing
- pseudoephedrine hydrochloride, cetirizine hydrochloride
- Where
- United Kingdom
- Volunteers
- 21 people
- Sponsor
- GlaxoSmithKline
Rhinitis, Allergic
Ability of a Cat Food to Reduce Respiratory Symptoms in Cat Allergic Patients
Cat allergy is the most common animal allergy, affecting approximately 1 in 5 adults worldwide. The prevalence of allergy to furry animals is increasing, and cat allergy is a major risk factor for the development of asthma and…
- Trial name
- CATS (NCT05656482)
- Testing
- Cats fed with PRO PLAN® LIVECLEAT®
- Where
- France
- Volunteers
- 50 people
- Sponsor
- MASK-air SAS
Seasonal Allergic Rhinitis
The Effect of Nasal Carbon Dioxide (CO2) Used As-Needed in the Symptomatic Treatment of Seasonal Allergic Rhinitis
The purpose of this study is to evaluate the effect of as-needed treatment with nasal carbon dioxide in patients with Seasonal Allergic Rhinitis symptoms.
- Trial name
- NCT00917020
- Testing
- Nasal CO2
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Capnia, Inc.
Allergic Rhinitis
A Study to Evaluate the Safety of Combination Montelukast/Loratadine in Mexican Participants With Allergic Rhinitis (MK-0476A-484)
The purpose of this study is to assess the safety and tolerability of montelukast 10 mg/loratadine 10 mg versus placebo in Mexican participants with allergic rhinitis.
- Trial name
- NCT01673620
- Testing
- Montelukast 10 mg/loratadine 10 mg
- Volunteers
- 69 people
- Sponsor
- Organon and Co
Allergic Rhinitis
A Study to Test a New Decongestant in Patients With Allergic Rhinitis Following a Nasal Allergen Challenge
An H3 receptor antagonist should reduce the congestion associated with allergic rhinitis. A nasal allergen challenge will be given to patients to induce rhinitis symptoms and acoustic rhinometry will be used to measure the…
- Trial name
- NCT00562120
- Testing
- Allegra, Allegra-D, PF-03654746
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- Pfizer
Allergic Conjunctivitis
Evaluation of the Onset and Duration of Action of RX-10045 in Allergic Conjunctivitis
To purpose of this study is to establish the efficacy and safety of RX-10045 ophthalmic solution in alleviating the signs and symptoms of allergic conjunctivitis
- Trial name
- NCT01639846
- Testing
- RX-10045, Vehicle for RX-10045 arm
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- C.T. Development America, Inc.
Allergic Rhinitis, Rhinoconjunctivitis
Evaluation of Tolerability and Safety of "Allergovac Poliplus" in Polysensitized Patients With Rhinitis or Allergic Rhinoconjunctivitis With or Without Asthma: A Study in Daily Clinical Practice
This is an observational prospective study to assess the tolerability and safety of treatment of SCIT Allergovac Poliplus polymerized in depot presentation.
- Conditions
- Allergic Rhinitis, Rhinoconjunctivitis, Asthma
- Trial name
- APOLO (NCT02844842)
- Testing
- Allergovac Poliplus
- Where
- 15 sites in Spain
- Volunteers
- 152 people
- Sponsor
- Roxall Medicina España S.A
Hayfever, Allergy Pollen
Breathe-Easy: Hayfever Care for Patients With Seasonal Allergic Rhinitis
This waitlist-controlled trial aims to evaluate the therapeutic effectiveness of Hayfever Care by assessing disease-specific symptoms over a 4-week period.
- Conditions
- Hayfever, Allergy Pollen, Allergic Rhinitis
- Trial name
- NCT06765239
- Testing
- Hayfever Care, Wait-list Control
- Where
- India
- Volunteers
- 63 people
- Sponsor
- Innowage Limited
Allergy, Rhinitis
Efficacy and Safety From a High-dosed Sublingual Grass Pollen Preparation
Efficacy and Safety from a high-dosed sublingual grass pollen preparation
- Conditions
- Allergy, Rhinitis, Conjunctivitis
- Trial name
- ALLEGRA6 (NCT00623701)
- Testing
- Allerslit forte
- Where
- Germany
- Volunteers
- 126 people
- Sponsor
- Allergopharma GmbH & Co. KG
Seasonal Allergic Rhinitis
A Study Comparing the Bioequivalence of Azelastine Hydrochloride and Fluticasone Propionate Nasal Spray (Apotex, Inc.) to That of Dymista™ Nasal Spray (Meda Pharmaceuticals, Inc.) in the Treatment of Seasonal Allergic Rhinitis
This study is to evaluate the equivalence of generic Azelastine Hydrochloride and Fluticasone Propionate Nasal Spray with that of the marketed drug, Dymista™ Nasal Spray, in the treatment of seasonal allergic rhinitis, and to…
- Trial name
- NCT02279563
- Testing
- Azelastine HCl and Fluticasone Propionate Nasal Spray, 137 µg/50 µg per spray, Dymista™ Nasal Spray
- Volunteers
- 595 people
- Sponsor
- Apotex Inc.
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