Clinical trials: Allergic Disease
Seasonal Allergic Rhinitis
A Study Comparing Montelukast With Placebo in Children With Seasonal Allergic Rhinitis (0476-219)(COMPLETED)
This study will evaluate the effect of montelukast compared to placebo in children during the spring allergic rhinitis season.
- Trial name
- NCT00968149
- Testing
- montelukast sodium
- Volunteers
- 413 people
- Sponsor
- Organon and Co
Allergic Rhinitis
Pilot Study of Intralymphatic Immunotherapy (ILIT) for House Dust Mite, Cat, and Dog Allergen in Allergic Rhinitis
The investigators performed open-labeled pilot study which evaluates the efficacy and safety of allergen-specific intralymphatic immunotherapy (ILIT) for allergens including Dermatophagoides farinae (Df), Dermatophagoides…
- Trial name
- pILIT (NCT02301884)
- Testing
- Allergen extract
- Where
- South Korea
- Volunteers
- 12 people
- Sponsor
- Gachon University Gil Medical Center
Rhinitis, Allergic
Washed Microbiota Transplantation for Allergic Rhinitis
Allergic rhinitis (AR) is characterized by sneezing, nasal congestion, nasal itching and nasal leakage and is caused by immunoglobulin E (IgE)-mediated reactions to inhaled allergens.
- Trial name
- NCT06372184
- Testing
- Washed Microbiota Transplantation
- Where
- China
- Volunteers
- 32 people
- Sponsor
- The Second Hospital of Nanjing Medical University
Asthma; Allergic Rhinitis
Tolerability and Pharmacokinetics of CSPCHA115 Capsules in Chinese Healthy Volunteers
A randomized, single-center, double-blind, ascending multiple-dose, placebo-controlled study to evaluate the tolerability and pharmacokinetics of CSPCHA115 capsules in Chinese healthy volunteers.
- Trial name
- NCT04161547
- Where
- China
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- CSPC ZhongQi Pharmaceutical Technology Co., Ltd.
Seasonal Allergic Rhinitis
Clinical Trial of STAHIST in Seasonal Allergic Rhinitis (SAR) Subjects
To report and compare total symptom scores, nasal symptom scores, post-nasal drip symptom scores, and adverse reactions in and between SAR subjects on active drug and SAR subjects on placebo.
- Trial name
- STA-2 (NCT01171664)
- Testing
- STAHIST
- Where
- 2 sites in United States
- Volunteers
- 100 people
- Sponsor
- Magna Pharmaceuticals, Inc.
Chronic Respiratory Diseases, Cystic Fibrosis
Breath Analysis and Arterial Stiffness in Patients With Respiratory Diseases
Assessment of cardiovascular disorders using echocardiography and arterial stiffness; comparative noninvasive assessment of volatile organic compound (eVOC) exhale breath patterns in patients with different chronic respiratory…
- Conditions
- Chronic Respiratory Diseases, Cystic Fibrosis, Lymphangioleiomyomatosis, Hypersensitivity Pneumonitis
- Trial name
- NCT05727852
- Testing
- Breath test using the Compact PTR-TOF-MS, Portable cardiac monitor "CardioQvark", Assessment of arterial stiffness using the VaSera VS-1500N
- Where
- Russia
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- I.M. Sechenov First Moscow State Medical University
Allergic Rhinitis
Free Diving Breathing Training in Allergic Rhinitis
The purpose of this study was to investigate the effects of diver-style breathing training on symptoms, pulmonary function, and respiratory muscle, in patients with allergic rhinitis.
- Trial name
- NCT07455968
- Testing
- Free diving breathing training
- Where
- Thailand
- Volunteers
- 30 people
- Sponsor
- Chulalongkorn University
Seasonal Allergic Rhinitis
Pilot Study to Evaluate Ear Acupressure Effects in Treating Seasonal Allergic Rhinitis
We hypothesize that ear acupressure will be effective in treating seasonal allergic rhinitis by changing the immune parameters and the psychological impact factors are associated with ear acupressure treatment outcome.
- Trial name
- NCT01921348
- Testing
- acupressure pellets
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of Mississippi Medical Center
Allergies
Understanding and Diagnosing Allergic Disease in Twins
The purpose of this study is to gain better understanding of how the immune system works in twins with and without allergic disease. Healthy volunteers are not specifically targeted.
- Trial name
- NCT01613885
- Testing
- No Intervention
- Where
- 2 sites in United States
- Volunteers
- 340 people, healthy volunteers welcome
- Sponsor
- Stanford University
Rhinitis, Allergic
The ARHINASD (Allergic Rhinitis in Pediatric Subjects With Nasal Septum Deviation) Project
Allergic rhinitis is one of the most common inflammatory conditions of the upper airway mucosa, especially in the pediatric population with a prevalence of approximately 25%.
- Trial name
- NCT06139185
- Testing
- Data collection
- Where
- 2 sites in Italy
- Volunteers
- 69 people
- Sponsor
- Federico II University
Allergic Rhinitis
Traditional Chinese Medicine on Gut Microbiota and Allergic Diseases
Allergic rhinitis is an importance disease in Taiwan with its high incidence about 20-30% and gradually increased annually. However, symptom relapse still bothered the majority of patients though there were certain advances in…
- Trial name
- NCT03033290
- Testing
- Bu-Zhong-Yi-Qi-Tang
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- Chang Gung Memorial Hospital
Rhinitis, Allergic, Perennial
Epinastine + Pseudoephedrine SR (Slow Release) Versus Epinastine Alone in Patients With Perennial Allergic Rhinitis
The aim of this trial is to evaluate the clinical efficacy and safety of Epinastine 10 mg + Pseudoephedrine 120 mg slow release (SR) administered twice a day, compared to Epinastine 10 mg alone administered twice daily.
- Trial name
- NCT02182518
- Testing
- Epinastine, Pseudoephedrine
- Volunteers
- 101 people
- Sponsor
- Boehringer Ingelheim
Allergic Rhinitis, Allergy
Effects of Long-Term Treatment With Nasally Inhaled Triamcinolone Acetonide in Children With Allergic Rhinitis
Seasonal/perennial allergic rhinitis (SAR/PAR) is a common childhood illness. One of the leading therapies for the treatment of SAR/PAR is intranasally inhaled corticosteroids (ICS).
- Conditions
- Allergic Rhinitis, Allergy, Growth
- Trial name
- NCT00189449
- Where
- United States
- Sponsor
- West Penn Allegheny Health System
Asthma, Allergic Rhinitis
PF and FeNO and Clinical Characteristics in Children Being Diagnosed Due to Suspicion of Allergic Diseases
The aim of this study is to assess the influence of kind of allergic disease, allergic profile, allergen exposure, treatment method on lung function parameters, fractional exhaled nitric oxide level in children suspected and…
- Conditions
- Asthma, Allergic Rhinitis, Atopic Dermatitis, Urticaria
- Trial name
- NCT01805635
- Testing
- No intervention
- Where
- Poland
- Volunteers
- 5,500 people, healthy volunteers welcome
- Sponsor
- Medical University of Lodz
Allergic Reaction
Allergy Potential of Omeza Collagen Matrix in Human Subjects Using the Skin Prick Method
Single-center, monadic, one day study utilizing the skin prick method to assess the allergy potential of Omeza Collagen Matrix in Human Subjects
- Trial name
- NCT04510376
- Testing
- Test Article, Positive Control, Negative Control
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Omeza, LLC
Rhinitis, Allergic, Perennial, Hay Fever
To Assess the Safety of Ciclesonide, Applied as a Nasal Spray at Three Dose Levels, in the Treatment of Perennial Allergic Rhinitis in Pediatrics (BY9010/M1-405)
The primary objective of this study is to demonstrate the safety of three dose levels of ciclesonide administered as an intranasal spray for six weeks, 200µg, 100µg or 25µg, once daily, in pediatric patients (ages 2-5 years) with…
- Trial name
- NCT00658918
- Testing
- Ciclesonide nasal
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- AstraZeneca
Allergic Rhinitis (AR)
EFFECT OF AYURVEDA TREATMENT IN ALLERGIC RHINITIS
Background Allergic Rhinitis is a chronic Th2-mediated inflammatory disorder associated with significant disease burden and impaired quality of life.
- Trial name
- ARAM (NCT07626099)
- Testing
- AYURVEDA treatment protocol, Control(Citrizine 10mg)
- Volunteers
- 104 people
- Sponsor
- Amrita Vishwa Vidyapeetham
Seasonal Allergic Rhinitis
A Study to Compare the Efficacy of QAV680 Against Placebo in Treating Seasonal Allergic Rhinitis in an Environmental Exposure Chamber
This study will compare the effectiveness of QAV680 against placebo in treating the symptoms of seasonal allergic rhinitis in an Environmental Exposure Chamber.
- Trial name
- NCT00784732
- Testing
- QAV680, Mometasone Furoate
- Where
- Canada
- Volunteers
- 44 people
- Sponsor
- Novartis
Bronchial Asthma
An Efficacy and Safety Study of Genolar® and Xolar® in the Persistent Atopic Bronchial Asthma
This is a randomized, double-blind, comparative, parallel-group study of the efficacy and safety of Genolar® and Xolair® in the treatment of persistent atopic bronchial asthma of moderate and severe course, whose symptoms are…
- Trial name
- NAP (NCT04607629)
- Testing
- Genolar® + Symbicort®, Xolair® + Symbicort®
- Where
- 24 sites in Russia
- Volunteers
- 192 people
- Sponsor
- AO GENERIUM
Seasonal Allergic Rhinitis (SAR)
A Study to Determine the Optimal Dose and Frequency of ALDP001 Nasal Spray in Adults With Seasonal Allergic Rhinitis Under Allergen Exposure
This study aims to evaluate the effectiveness and safety of ALDP001 Nasal Spray in treating seasonal allergic rhinitis, and to identify the optimal dosage and administration frequency for this formulation.
- Trial name
- ALDP001 (NCT07219849)
- Testing
- ALDP001 Nasal Spray
- Where
- Canada
- Volunteers
- 164 people, healthy volunteers welcome
- Sponsor
- Alixer Nexgen Therapeutics Limited