Clinical trials: Allergic Disease
Asthma, Rhinitis
Oral Bacteria and Allergic Disease in Children
This study will see if bacteria differ between children who have allergies or asthma and children who do not have allergies or asthma. Previous research suggests that some bacteria may protect against allergies and asthma.
- Conditions
- Asthma, Rhinitis, Eczema, Respiratory Sounds
- Trial name
- NCT00438646
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- National Institute of Environmental Health Sciences (NIEHS)
Rhinitis, Allergic
Microbial Study of Sublingual Immunotherapy Spray in Patients With Allergic Rhinitis
The incidence of allergic rhinitis (AR) in Chinese adults was reported to be as high as 24.1% and 16.8% in children. The current symptomatic treatment has the disadvantage of poor efficacy and cannot change the natural course of…
- Trial name
- NCT06741787
- Testing
- Patients desensitized by sublingual spray
- Where
- China
- Volunteers
- 100 people
- Sponsor
- The First Affiliated Hospital with Nanjing Medical University
Allergic Rhinitis
Nasonex® Nasal Suspension 50 μg Long-term Designated Drug Use Investigation (Study P05876)
The investigation will be conducted to define safety and efficacy under the conditions of post-marketing use of this drug in subjects with allergic rhinitis.
- Trial name
- NCT00903721
- Testing
- mometasone furoate
- Volunteers
- 3,806 people
- Sponsor
- Organon and Co
Probiotic, Ocular Surface Disease
Efficacy and Safety of Oral Probiotics on Ocular Symptoms and Gut Microbiome of Children with Vernal Keratoconjunctivitis
The primary goal of this study is to determine the effects of oral probiotics on the severity of ocular symptoms and the alterations of the gut microbiome of children (4-18 years old) with vernal keratoconjunctivitis.
- Conditions
- Probiotic, Ocular Surface Disease, Ocular Diseases, Ocular Dryness
- Trial name
- NCT06793514
- Testing
- Probiotic
- Volunteers
- 32 people
- Sponsor
- Mohsen Pourazizi
Asthma, Allergic Rhinitis
Molekule for Allergic Rhinitis/Asthma
Exposure to airborne allergens and pollutants is linked to symptom severity of allergies, asthma and other respiratory problems.
- Conditions
- Asthma, Allergic Rhinitis, Allergic Conjunctivitis
- Trial name
- NCT03627689
- Testing
- Active air purifier in respiratory allergies/asthma
- Where
- United States
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Molekule
Seasonal Allergic Rhinitis, SAR
A Phase III Study to Assess the Efficacy and Safety of PG-011 Nasal Spray in Adults With Moderate to Severe Seasonal Allergic Rhinitis
The study is a multicenter, randomized, double-blind, placebo-controlled seamless and adaptive-designed phase IIb/III study encompassing a phase IIb and a phase III component, phase IIb is a dose-ranging part and has been done…
- Trial name
- Pumecitinib (NCT07146126)
- Testing
- PG-011 nasal spray 0.6%(twice daily)
- Where
- 38 sites in China
- Volunteers
- 600 people
- Sponsor
- Prime Gene Therapeutics Co., Ltd.
Rhinitis, Allergic, Seasonal, Conjunctivitis, Allergic
Twin SUBLIVAC® Grasses Clinical Efficacy Study
To show that treatment with SUBLIVAC® Grasses is clinically effective by means of reduction in allergic symptoms and/or use of allergic symptomatic medication in subjects suffering from IgE mediated allergic complaints triggered…
- Trial name
- NCT00422149
- Testing
- SUBLIVAC® Grasses treatment
- Where
- 60 sites in Belgium, Germany and 2 more
- Volunteers
- 350 people
- Sponsor
- HAL Allergy
Allergic Rhinitis, Perennial Allergic Rhinitis
A 6 Month Safety and Efficacy Study of Once Daily Ciclesonide Hydrofluoroalkane (HFA) in the Treatment of Perennial Allergic Rhinitis (PAR) in Subjects 12 Years and Older
This is a 6-month multi-center, randomized, double-blind, placebo-controlled, parallel group, efficacy and safety study of ciclesonide HFA nasal aerosol administered once-daily to male and female subjects 12 years or older…
- Trial name
- NCT00953147
- Testing
- Ciclesonide HFA 80 mcg, Ciclesonide HFA 160 mcg
- Where
- 45 sites in United States
- Volunteers
- 1,110 people
- Sponsor
- Sumitomo Pharma America, Inc.
Asthma, House Dust Mite Allergy
Safety Study of Sublingual Immunotherapy Tablets of House Dust Mite Allergen Extracts
The purpose of this study is to investigate the safety of different doses of sublingual tablets of house dust mite allergen extracts in adults with house dust mite-associated allergic asthma.
- Trial name
- NCT01608243
- Testing
- SLIT tablets of house dust mite allergen extracts
- Where
- France
- Volunteers
- 94 people
- Sponsor
- Stallergenes Greer
Rhinitis, Allergic
To Evaluate the Efficacy and Safety of Levocetirizine Versus Loratadine for Treatment of Seasonal Allergic Rhinitis
To Evaluate the Efficacy and Safety of Levocetirizine Versus Loratadine for Treatment of Seasonal Allergic Rhinitis
- Conditions
- Rhinitis, Allergic, Seasonal
- Trial name
- NCT00525278
- Testing
- Levocetirizine dihydrochloride
- Volunteers
- 67 people
- Sponsor
- UCB Pharma
Eosinophilic Esophagitis
Efficacy and Safety APT-1011 in Adult Subjects With Eosinophilic Esophagitis (EoE) (FLUTE-2)
This is a 2-part randomized, double-blind, placebo-controlled study followed by an open-label extension (OLE) of APT-1011 in adults with EoE.
- Trial name
- FLUTE-2 (NCT04281108)
- Testing
- APT-1011, Esophagogastroduodenoscopy
- Where
- 56 sites in United States, Australia and 1 more
- Volunteers
- 143 people
- Sponsor
- Ellodi Pharmaceuticals, LP
Allergic Rhinitis, Peanut Allergies
The Role of Filaggrin Mutations and Sensitization Pathways in Allergic Rhinitis and Peanut Allergy
Caucasian male and female participants age 18 years of age and older will be enrolled in this study if they have known birch or peanut allergies or known to be non-atopic.
- Trial name
- NCT02745418
- Where
- Canada
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Dr. Anne Ellis
Allergic Bronchopulmonary Aspergillosis
Multicenter Registration Study on Allergic Bronchopulmonary Aspergillosis
To understand the current diagnosis and treatment status of ABPA patients, observe their clinical characteristics, prognosis, and treatment outcomes, and identify the relevant factors for poor prognosis in patients.
- Trial name
- NCT06645210
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Peking University Third Hospital
Treatment Failure, HIV or AIDS, CD4 Cell Counts
Effectiveness of Efavirenz-based Regimen in HIV-1-infected Patients With Nevirapine Hypersensitivity
The primary objective of this study is to compare the effectiveness of EFV-based regimens in HIV-1-infected patients who; (1) were previously allergic to NVP and stopped all ARV simultaneously; (2) were previously allergic to NVP…
- Trial name
- NCT01044810
- Testing
- Efavirenz-based regimens
- Where
- Thailand
- Volunteers
- 559 people
- Sponsor
- Bamrasnaradura Infectious Diseases Institute
Atopic Dermatitis, Food Allergy in Children
Preventing Atopic Dermatitis and ALLergies in Children
The primary objective is of the PreventADALL study is to test if primary prevention of allergic diseases is possible by simple and low cost strategies, and secondary to asses the impact of xenobiotic exposure and microbiota in…
- Conditions
- Atopic Dermatitis, Food Allergy in Children, Asthma, Rhinitis, Allergic
- Trial name
- PreventADALL (NCT02449850)
- Testing
- Food intervention, Skin care
- Where
- Norway
- Volunteers
- 2,701 people, healthy volunteers welcome
- Sponsor
- Oslo University Hospital
Seasonal Allergic Rhinitis
A Study Evaluating the Efficacy and Impact on Health-related Quality of Life of Levocetirizine in Adults With Seasonal Allergic Rhinitis
The study objective is to investigate the efficacy of levocetirizine in reducing symptoms associated with seasonal allergic rhinitis and in improving rhinitis-related Quality of Life
- Trial name
- NCT00621959
- Testing
- levocetirizine dihydrochloride
- Where
- 26 sites in United States
- Volunteers
- 596 people
- Sponsor
- UCB Pharma
Allergic Conjunctivitis
Safety and Efficacy Study of AL-53817 and AL-78843 Ophthalmic Solutions for Allergic Conjunctivitis
The purpose of this study is to evaluate two investigational ophthalmic solutions for reduction in ocular redness in subjects with allergic conjunctivitis.
- Trial name
- NCT02079649
- Testing
- AL-53817 Ophthalmic Solution, 0.1%, AL-78843 Ophthalmic Solution, 0.03%, Dexamethasone Ophthalmic Suspension, 0.1%
- Volunteers
- 224 people
- Sponsor
- Alcon Research
Perennial Allergic Rhinitis
Long Term Safety and Efficacy of Fixed Dose Combination GSP 301 Nasal Spray (NS) in the Treatment of Perennial Allergic Rhinitis (PAR)
To evaluate the long term safety and efficacy of GSP 301 NS compared to 2 placebo NS formulations for the treatment of perennial allergic rhinitis (subjects 12 years of age and older)
- Trial name
- GSP 301-303 (NCT02709538)
- Testing
- GSP 301 NS
- Where
- 34 sites in United States
- Volunteers
- 601 people
- Sponsor
- Glenmark Specialty S.A.
Allergic Conjunctivitis
Use of BEPREVE (Bepotastine Besilate Ophthalmic Solution) 1.5% for Allergic Conjunctivitis and Contact Lenses
The purpose of this study is to assess if BEPREVE (bepotastine besilate ophthalmic solution) 1.5% will have an effect on contact lens wear in patients with contact lens intolerance due to allergic conjunctivitis.
- Trial name
- NCT01337557
- Testing
- Bepotastine
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Hom, Milton M., OD, FAAO
Rhinitis, Allergic
A Study to Evaluate Changes in Nasal Airflow of Loratadine/Pseudoephedrine Tablet and Fluticasone Propionate Nasal Spray in Subjects Following Allergen Exposure
The purpose of the study is to evaluate changes in nasal airflow caused by loratadine 5 mg/pseudoephedrine sulfate 120 mg (Claritin D) tablet and fluticasone propionate 50 mcg per spray nasal spray (Flonase) in subjects suffering…
- Trial name
- NCT03443843
- Testing
- loratadine + pseudoephedrine sulfate (BAY818725/Claritin-D), Fluticasone Propionate
- Where
- Canada
- Volunteers
- 82 people
- Sponsor
- Bayer
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