Clinical trials: Allergic Disease
Allergic Asthma
A Study of Omalizumab in the Prevention of Allergen Induced Airway Obstruction in Adults With Mild Allergic Asthma
This was a multicenter, randomized, double-blind, parallel-group, three-arm, placebo-controlled study designed to demonstrate the efficacy of two different formulations of omalizumab compared with placebo in reducing the airway…
- Trial name
- AQUA (NCT00434434)
- Testing
- omalizumab
- Volunteers
- 61 people
- Sponsor
- Genentech, Inc.
Rhinitis, Allergic, Perennial
Effectiveness of Qufeng Shengshi Fang on Treatment of Allergic Rhinitis.
This is a controlled clinical trials about traditional Chinese medicine named Qufeng Shengshi Fang，which consisted of cicada slough，bombyx batryticatus，radix angelicae，radix sileris，honeysuckle flower，forsythia，lithospermum and…
- Trial name
- NCT02653339
- Testing
- Qufeng Shengshi Fang and Loratadine, Loratadine
- Where
- China
- Volunteers
- 180 people
- Sponsor
- Peking Union Medical College Hospital
Asthma, Allergic Rhinitis
Clinical Response to Rhinovirus Challenge
Rhinovirus (RV) infections represent the most common cause of asthma exacerbations in children and adolescents. The investigators hypothesize that the immune responses generated in the nose of allergic rhinitics and asthmatics…
- Trial name
- NCT02910401
- Testing
- Rhinovirus (GMP RV16 HRV-16)
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- University of Virginia
Seasonal Allergic Rhinitis, Asthma
Safety Study of Ragweed-SPIRE in Subjects With Ragweed Allergies and Asthma
The purpose of this study is to determine whether it is safe to administer Ragweed-SPIRE to subjects suffering from both ragweed allergy and asthma.
- Trial name
- NCT02061670
- Testing
- Ragweed-SPIRE
- Where
- 5 sites in Canada
- Volunteers
- 55 people
- Sponsor
- Circassia Limited
Allergic Rhinitis, Allergic Asthma
Safety and Immunogenicity of Cat-allergen Intralymphatic Immunotherapy in Patients With Cat Allergy With and Without Asthma
The goal of this clinical trial is to evaluate the safety and tolerability of intralymphatic immunotherapy (ILIT) with ALUTARD SQ Felis domesticus in patients with cat allergy-induced allergic rhinitis and asthma.
- Trial name
- NCT06960382
- Testing
- ALUTARD SQ® Felis domesticus
- Where
- Switzerland
- Volunteers
- 36 people
- Sponsor
- University of Zurich
Allergic Contact Dermatitis
Clinical Evaluation of T.R.U.E. Test Allergens in Children an Adolescents
The objective of the study was to evaluate the diagnostic performance and safety of T.R.U.E. Test allergens in pediatric subjects aged 6-17 years old.
- Trial name
- NCT01797562
- Testing
- Panels 1.3, 2.2 and 3.2 experimental allergens
- Where
- 4 sites in United States
- Volunteers
- 116 people
- Sponsor
- Allerderm
Allergy
Single Ascending-dose Study of the Safety, Tolerability, and Pharmacokinetics of REGN1908-1909 in Allergic, Adult Subjects
The primary objective of the study is to assess the safety and tolerability of single ascending doses of subcutaneously (SC) administered REGN1908-1909 in allergic, adult subjects.
- Trial name
- NCT01922661
- Testing
- REGN1908-1909
- Where
- 2 sites in United States
- Volunteers
- 24 people
- Sponsor
- Regeneron Pharmaceuticals
Allergic Rhinitis Due to House Dust Mite, Allergic Asthma Due to Dermatophagoides Farinae
N.I.S of AIT in Adult Patients With House Dust Mite Allergy in Real Practice in France
Non-interventional study to investigate the safety and tolerability of allergy immunotherapy ACARIZAX® 12 SQ-HDM in real-life clinical practice in adults patients (>18 years) with house dust mite allergy over a period of 12…
- Conditions
- Allergic Rhinitis Due to House Dust Mite, Allergic Asthma Due to Dermatophagoides Farinae, Allergic Asthma Due to Dermatophagoides Pteronyssinus
- Trial name
- CARIOCA (NCT03746860)
- Testing
- Tablet, Dispersible
- Where
- France
- Volunteers
- 1,508 people
- Sponsor
- ALK-Abelló A/S
Vernal Keratoconjunctivitis
Tacrolimus Eye Drops in Treatment of Vernal Keratoconjunctivitis
The purpose of the study is to evaluate efficacy and safety of topical Tacrolimus eye drops in different concentrations in treatment of vernal keratoconjunctivitis (VKC) comparing it with Steroid based usual topical regimen
- Trial name
- NCT07138742
- Testing
- Steroid eye drops, Tacrolimus eye drops
- Volunteers
- 90 people
- Sponsor
- Sohag University
Allergic Bronchopulmonary Aspergillosis, Severe Asthma
Real-World Effectiveness of Benralizumab in Allergic Bronchopulmonary Aspergillosis
An open-label study will evaluate effects of Benralizumab in the treatment of severe asthma in patients with allergic bronchopulmonary aspergillosis
- Conditions
- Allergic Bronchopulmonary Aspergillosis, Severe Asthma, ABPA
- Trial name
- NCT07530770
- Testing
- Fasenra
- Where
- 2 sites in China
- Volunteers
- 20 people
- Sponsor
- Qianfoshan Hospital
Allergic Rhinitis, Allergic Rhinoconjunctivitis
PURETHAL Birch RUSH Study
This study investigates the safety of two up-dosing regimen. The safety of PURETHAL Birch will be evaluated in a rush regimen (maximum dose reached in 3 injections during 3 weeks) compared to the conventional regimen (maximum…
- Trial name
- NCT01918956
- Testing
- PURETHAL Birch, 20.000 AUM/ml
- Where
- 8 sites in Poland
- Volunteers
- 120 people
- Sponsor
- HAL Allergy
Asthma and Allergic Rhinitis
Role of Montelukast in Asthma and Allergic Rhinitis Patients
To determine the effect of Montelukast in Asthma and Allergic rhinits patients
- Trial name
- MAAP (NCT03380975)
- Testing
- Montelukast 10mg
- Where
- Pakistan
- Volunteers
- 600 people
- Sponsor
- Clinision
Allergic Diseases, Asthma
Vaginal Microbiome Exposure and Immune Responses in C-section Infants
The purpose of this research study is to assess at how differences in the microbiome (naturally occurring bacteria) of a baby may protect, or put a baby at risk, for allergic problems.
- Trial name
- NCT03567707
- Testing
- Vaginal seeding, Standard care, Post-seeding Care
- Where
- 2 sites in United States
- Volunteers
- 114 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Acute Urticaria
Pilot Phase III Clinical Trial of JDP-205 IV Injection for Treatment of Acute Urticaria
This is a multicenter, parallel group, randomized, double-blind pilot Phase III clinical study of JDP-205 (cetirizine) injection, versus diphenhydramine injection, 50 mg/mL (Benadryl or generic equivalent), in approximately 36…
- Trial name
- NCT02023164
- Testing
- JDP-205 Injection, Diphenhydramine
- Where
- 6 sites in United States, Canada
- Volunteers
- 36 people
- Sponsor
- JDP Therapeutics, Inc.
ABPA, Allergic Bronchopulmonary Aspergillosis
ML-Based ABPA Recurrence Prediction and Clinical Utility
This multicenter bidirectional cohort study aims to develop and externally validate a machine learning model for predicting the risk of acute exacerbation within 1 year in patients with allergic bronchopulmonary aspergillosis…
- Conditions
- ABPA, Allergic Bronchopulmonary Aspergillosis, Allergic Bronchopulmonary Aspergillosis (ABPA), Acute Exacerbation
- Trial name
- ABPA-ML (NCT07714863)
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Qianfoshan Hospital
Allergic Rhinitis
Comparison of Montelukast and Azelastine in Treatment of Moderate to Severe Allergic Rhinitis
Comparison of Montelukast and Azelastine In treatment of Allergic Rhinitis Allergic intent is one of the most common diseases of the respiratory system that has a devastating effect on the quality of life.
- Trial name
- NCT04561687
- Testing
- Montelukast, Azelastine, Budesonide
- Where
- Iran
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Shiraz University of Medical Sciences
Anakinra, Kineret
A Pilot Study Using Anakinra/Kineret for the Treatment of Patients With Severe Atopic Dermatitis
Background: Severe atopic dermatitis, also known as eczema, is a chronic inflammatory skin condition that affects both children and adults and causes severe itching and skin redness.
- Conditions
- Anakinra, Kineret, Atopic Dermatitis, Eczema
- Trial name
- NCT01122914
- Testing
- Anakinra
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Food Allergy, Asthma
Assessing Risk of Food Insecurity Within Households of Children With Food Allergy
Our central hypothesis is that dietary limitations introduced by food allergy will contribute to increased food insecurity in households with food allergic children when compared to food insecure households without food allergic…
- Conditions
- Food Allergy, Asthma, Allergic Rhinitis, Atopic Dermatitis
- Trial name
- NCT01897506
- Where
- United States
- Volunteers
- 650 people
- Sponsor
- Arkansas Children's Hospital Research Institute
Allergic Diseases
Oral Probiotics to Allergic Pregnant Mother and Their Offspring to Prevent Allergic Disease
The aim of the study is first to detect the difference of the intestinal microbiome between allergic pregnant mother and the non-allergic pregnant mother using the next generation sequence, all postnatal infants will collect the…
- Trial name
- NCT03873792
- Testing
- Physician diagnoses a history of asthma or eczema or allergic rhinitis or health pregnant women
- Where
- Taiwan
- Volunteers
- healthy volunteers welcome
- Sponsor
- China Medical University Hospital
Asthma, Respiratory Disease
Symptoms, Respiratory Dysfunction and Frailty Level in Allergic and Eosonophilic Asthmatics
The aim of this study is to determine the level of respiratory dysfunction, symptoms and frailty in patients with asthma according to different endophenotypes (allergic and eosonophilic asthma).
- Conditions
- Asthma, Respiratory Disease, Fragility
- Trial name
- NCT06796894
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Hacettepe University
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