Clinical trials: Allergic Disease
Allergic Rhinitis
The Efficacy Of Elonide Nasal Corticosteroids In Managing Allergic Rhinitis
The aim of this clinical study is to compare the efficacy of Elonide Nasal Spray to Nasonex Nasal Spray and Placebo (non-active ingredient) in the management of allergic rhinitis. There are two hypotheses of this study: 1.
- Trial name
- NCT05912192
- Testing
- Elonide Nasal Spray, Nasonex Nasal Spray, Normal saline
- Where
- Malaysia
- Volunteers
- 163 people, healthy volunteers welcome
- Sponsor
- National University of Malaysia
Allergic Rhinitis
Evaluation of Treatments for Allergic Rhinitis (Rhinal 2)
The goal of this clinical study is to perform a post-market clinical follow-up of 2 medical devices (liquid bandage in the form of a spray : ALLERSPRAY G (product A - code AAG), PCNS (product B - code PC) indicated for…
- Trial name
- RHINAL 2 (NCT06810947)
- Testing
- ALLERSPRAY-G (device A), PCNS (device B)
- Where
- France
- Volunteers
- 35 people
- Sponsor
- University Hospital, Clermont-Ferrand
Rhinitis
Effect Of Probiotic Lactobacillus Paracasei Lp-33 For The Management Of Rhinitis In People Sensitized To Allergens
The aim of the study is to show an improvement of quality of life on the 5th week of product consumption (probiotic Lactobacillus paracasei LP-33)(as assessed by RQLQ global score) in subjects with persistent allergic rhinitis…
- Trial name
- BionAtlanta (NCT01096615)
- Testing
- Lactobacillus paracasei LP-33
- Where
- 125 sites in France
- Volunteers
- 500 people
- Sponsor
- Merck Medication Familiale
Allergic Rhinitis
Brain-derived Neurotrophic Factor (BDNF) Single Nucleotide Gene Polymorphism and Nerve Growth Factor as Risk Factors That Increase Severity of Allergic Rhinitis
Allergic diseases such as asthma, allergic rhinitis (AR) and atopic dermatitis affect more than 25% of the world population and are the leading cause of illness in children.
- Trial name
- NCT05907733
- Testing
- Genotyping.
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Sohag University
Allergic Rhinoconjunctivitis
Long-term Efficacy and Safety Study With Oralgen Grass Pollen
This study is designed to give additional information on the efficacy, safety and local effects (tolerability) of a dose of sublingual immunotherapy administered once a day, during a second grass pollen season.
- Trial name
- NCT00824447
- Testing
- Oralgen
- Where
- 39 sites in Bulgaria, Czechia and 5 more
- Volunteers
- 356 people
- Sponsor
- Artu Biologicals
Asthma
Safety Study of a Vitamin E Supplement in Normal Volunteers and Those With Both Allergy and Asthma
Gamma tocopherol (gt) is a naturally occurring form of vitamin E that is found in many foods, and is also commercially available as a vitamin supplement.
- Trial name
- NCT00386178
- Testing
- Vitamin E supplement rich in gamma tocopherol
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Interstitial Lung Disease Due to Systemic Disease (Disorder), Interstitial Lung Disease Due to Systemic Disease (Telomere Biology Disorder)
Occupational and Environmental Exposures Analysis in Interstitial Lung Diseases.
The OCEAN-ILD study is designed to prospectively evaluate the prevalence and clinical relevance of environmental and occupational exposures in a large Italian cohort of patients affected by any ILD, using a standardised exposure…
- Conditions
- Interstitial Lung Disease Due to Systemic Disease (Disorder), Interstitial Lung Disease Due to Systemic Disease (Telomere Biology Disorder), Exposure Occupational, Occupational Exposure
- Trial name
- OCEAN-ILD (NCT07577115)
- Testing
- standard interview
- Where
- Italy
- Volunteers
- 1,000 people
- Sponsor
- Istituto Clinico Humanitas
Seasonal Allergic Rhinitis, Hay Fever
Study in Adult and Adolescent Subjects With Seasonal Allergic Rhinitis (SAR)
The purpose of the study is to assess the efficacy and safety of an investigational nasal aerosol compared with placebo nasal aerosol in the treatment of seasonal allergic rhinitis.
- Trial name
- NCT01024608
- Testing
- Beclomethasone dipropionate
- Where
- 4 sites in United States
- Volunteers
- 340 people
- Sponsor
- Teva Branded Pharmaceutical Products R&D, Inc.
Allergic Rhinitis
Safety and Efficacy Study With Allergen Extracts of House Dust Mites for Specific Sublingual Immunotherapy
The objective of this clinical trial is to assess the safety and efficacy of sublingual application of allergen extracts for specific immunotherapy in patients suffering from perennial allergic rhinitis due to house dust mites.
- Trial name
- NCT01014325
- Testing
- Allergen extract
- Where
- Spain
- Volunteers
- 130 people
- Sponsor
- Roxall Medizin
Allergy to House Dust Mite, Allergic Asthma
Effects of Tregalizumab on Allergen-induced Airway Responses and Airway Inflammation in Asthmatic Patients
The study will be conducted as a randomized, double-blind, placebo-controlled, single-center study in adult patients with mild controlled allergic asthma and house dust mite allergy.
- Trial name
- Tregulaire (NCT04673591)
- Testing
- Tregalizumab
- Where
- Germany
- Volunteers
- 42 people
- Sponsor
- T-Balance Therapeutics GmbH
Pulmonary Hypertension, Hypersensitivity Pneumonitis
Predictors of Pulmonary Hypertension in Patients With Hypersensitivity Pneumonitis
Hypersensitivity pneumonitis (HP) is a complex immune mediated disorders caused by repeated inhalation of and sensitization to wide range of antigens including organic particles and chemical compounds, leading to exaggerated…
- Trial name
- NCT05458635
- Testing
- Right heart catheter
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Cairo University
Anaphylaxis, Allergy
Clinical Investigation on Allergic-like Reactions and Oculo-respiratory Syndrome After the H1N1 Pandemic Vaccine
During the 2009-2010 immunization campaign against pandemic H1N1, some people reported having allergic-like reactions (anaphylaxis(a shock-like reaction), hives, swelling, etc.).
- Conditions
- Anaphylaxis, Allergy, Oculorespiratory Syndrome, Allergic-like Reactions
- Trial name
- NCT01247415
- Where
- 7 sites in Canada
- Volunteers
- 138 people
- Sponsor
- PHAC/CIHR Influenza Research Network
Rhinitis, Allergic, Seasonal, Rhinitis, Allergic, Perennial
Study for the Treatment of Intermittent Allergic Rhinitis With Desloratadine (Study P04683)
This study will investigate the effectiveness of desloratadine in treating subjects with allergic rhinitis (AR) who meet the criteria for intermittent allergic rhinitis.
- Trial name
- NCT00406783
- Testing
- 5-mg Desloratadine
- Volunteers
- 547 people
- Sponsor
- Organon and Co
Allergic Rhinitis
Comparison of Different Up-dosing Schedules With Osiris
The purpose of this study is to compare different up-dosing schedules with Osiris.
- Trial name
- NCT01240954
- Testing
- OSIRIS, OSIRIS other concentration 1, OSIRIS other concentration 2
- Where
- Poland
- Volunteers
- 210 people
- Sponsor
- ALK-Abelló A/S
Atopic Dermatitis, Asthma
Prospective Longitudinal Observational Research in Atopic Dermatitis
Atopic dermatitis (AD) is a frequent chronic relapsing inflammatory skin disorder, characterized by intensely itchy eczema. AD usually starts within the first 2 years of life.
- Conditions
- Atopic Dermatitis, Asthma, Atopic Dermatitis and Related Conditions
- Trial name
- ProRaD (NCT04240522)
- Where
- Switzerland
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Rhinitis, Allergic, Perennial
Repeated Dosing Clinical Trial of HL151
The purpose of this study is to assess the pharmacokinetic characteristics of bepotastine after multiple oral administration of TALION tab., a IR formulation of bepotastine as reference drug and HL151, a SR formulation of…
- Trial name
- NCT02686294
- Testing
- HL151, TALION tab.
- Where
- South Korea
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Hanlim Pharm. Co., Ltd.
Allergic Rhinitis
Component Resolved Diagnostics (CRD) and mHealth for Pollen Allergy In Southern Europe.
Pollen allergic rhinitis is a very common condition whose symptomatic treatment is not always sufficient or satisfactory. The indication for allergic immunotherapy (IT) therefore often arises.
- Trial name
- IT-2020-MC (NCT03636919)
- Testing
- e-BOOK
- Where
- France
- Volunteers
- 900 people
- Sponsor
- Assistance Publique Hopitaux De Marseille
Healthy, Asthma
A Study in Healthy Subjects and Mild Asthmatics to Investigate Pharmacokinetics of AZD5423 When Administered in Different Ways
A study in healthy subjects and mild asthmatics to investigate Pharmacokinetics of AZD5423 when administered in different ways.
- Trial name
- NCT01310322
- Testing
- AZD5423
- Where
- United Kingdom
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Asthma, Allergic Asthma
Towards Targeting the ORigin of the Inflammatory Cascade in Allergic Asthma
Allergic asthma is a complex and heterogeneous disease caused by excessive responses to inhaled allergens. Current medication, including corticosteroids and bronchodilators, does not act on the origin of inflammation but rather…
- Trial name
- ORIENT (NCT04264377)
- Testing
- Bronchoscopy
- Where
- Netherlands
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- University Medical Center Groningen
Allergy, Rhinitis
Safety Clinical Trial With Depigopid 50% Grasses/50% Olea Europaea(2000DPP/ml) or Depigoid 50% Grasses/50% Parietaria Judaica(2000DPP/ml).
The primary objective of this study is to evaluate the safety and tolerance of a rush build up administration of Depigoid forte pollen and the first maintenance dose administered 4 weeks later.
- Conditions
- Allergy, Rhinitis, Rhinoconjunctivitis, Seasonal Asthma
- Trial name
- NCT01734265
- Testing
- Depigoid 50% Grasses/50% Olea europaea (2000DPP/ml), Depigoid 50% Grasses/50% Parietaria judaica (2000DPP/ml)
- Where
- 4 sites in Spain
- Volunteers
- 63 people
- Sponsor
- Laboratorios Leti, S.L.
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.