Clinical trials: Allergic Disease
Seasonal Allergic Rhinitis
Phase II Study of JT002 in the Treatment of Seasonal Allergic Rhinitis in Adults
The study included three phases: the treatment introduction period (4-7 days before randomization), the treatment period (14 days after randomization) and the follow-up period (7 days after the last dose).
- Trial name
- NCT06861101
- Testing
- JT002 Nasal spray
- Where
- 44 sites in China
- Volunteers
- 370 people
- Sponsor
- Shanghai JunTop Biosciences Co., LTD
Rhinitis, Allergic
Ability of a Cat Food to Reduce Respiratory Symptoms in Cat Allergic Patients
Cat allergy is the most common animal allergy, affecting approximately 1 in 5 adults worldwide. The prevalence of allergy to furry animals is increasing, and cat allergy is a major risk factor for the development of asthma and…
- Trial name
- CATS (NCT05656482)
- Testing
- Cats fed with PRO PLAN® LIVECLEAT®
- Where
- France
- Volunteers
- 50 people
- Sponsor
- MASK-air SAS
Allergy
Changes in the Immune Response and Skin Reactivity of Grass Pollen Allergic Patients Treated With ALK Grass Tablets
We plan to determine changes in the immune system during the allergic response to grass pollen allergens. We have chosen a particular element of the immune response, the immunoglobulin G4 (IgG4) as an indicator.
- Trial name
- NCT00413556
- Testing
- ALK Grass tablet
- Where
- Spain
- Volunteers
- 76 people
- Sponsor
- ALK-Abelló A/S
Peanut Allergy
Safety Study of Viaskin Peanut to Treat Peanut Allergy
This study evaluates the safety of Viaskin Peanut 250 µg in the treatment of peanut allergy in children from 4 to 11 years of age.
- Trial name
- REALISE (NCT02916446)
- Testing
- Viaskin Peanut 250 µg
- Where
- 32 sites in United States, Canada
- Volunteers
- 393 people
- Sponsor
- DBV Technologies
Allergic Contact Dermatitis
Patient Experience and Quality of Patch Testing on the Legs vs Back
The gold standard for the diagnosis of allergic contact dermatitis is patch testing, during which allergens are affixed to the skin underneath tape and left for multiple days.
- Trial name
- NCT06191627
- Testing
- Patch testing
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- HealthPartners Institute
Acute Bronchiolitis, Asthma
Acute Bronchiolitis in Infants and Allergic Asthma
Predicting the risk of allergenic sensitizations and asthma development in the first year of life is difficult. Investigator decided to follow prospectively two cohorts of infants with acute bronchiolitis, hospitalized or treated…
- Conditions
- Acute Bronchiolitis, Asthma, Allergy
- Trial name
- NCT03915197
- Testing
- Pneumological evaluation
- Where
- France
- Volunteers
- 320 people
- Sponsor
- University Hospital, Clermont-Ferrand
Rhinitis, Allergic
The Efficacy and Safety of Cettum for Perennial Allergic Rhinitis
The purpose of this study is verify the efficacy and safety of Cettum (Electrical moxibustion) for patients with perennial allergic rhinitis.
- Trial name
- NCT03342105
- Testing
- Cettum, Acupuncture
- Volunteers
- 40 people
- Sponsor
- Eun Jung Kim
Sleep Apnea, Allergic Rhinitis
Impact of Pollution on Allergic Rhinitis and Sleep Quality: the POLLAR Study
It has been demonstrated that allergic rhinitis (AR) reduces sleep quality by some components such as nasal obstruction. Pollution and allergen exposure worsening AR, sleep quality is deteriorated.
- Conditions
- Sleep Apnea, Allergic Rhinitis, Allergic Asthma, Pollution Exposure
- Trial name
- POLLAR (NCT03776773)
- Testing
- Pollution exposure
- Where
- France
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- University Hospital, Grenoble
Peanut Allergy
Oral Immunotherapy for Peanut Allergic Patients
Multicenter, double-blind, randomized, placebo-controlled phase I/II study to determine the safety, tolerability, potential efficacy and dose finding of INP20, an oral immunotherapy in peanut-allergic patients.
- Trial name
- NCT04163562
- Testing
- INP20
- Where
- 2 sites in Spain
- Volunteers
- 50 people
- Sponsor
- InnoUp Farma S.L.
Asthma, Allergic
ICS Treatment Compliance of Asthma Patients
The introduction of inhaled medication as the primary treatment for asthma has led to substantial improvements in asthma control [1, 2].
- Trial name
- NCT02990117
- Testing
- No Intervention
- Volunteers
- 350 people
- Sponsor
- First Affiliated Hospital Xi'an Jiaotong University
Eosinophilic Esophagitis (EoE)
A Study of Dupilumab in Small Children With an Allergic Condition of the Esophagus (Food Pipe): Eosinophilic Esophagitis
This study is researching an experimental drug called dupilumab (called "study drug"). The study is focused on children with active eosinophilic esophagitis (EoE; an inflammatory disease of the esophagus) which impacts feeding…
- Trial name
- EoE-TOTs (NCT07112378)
- Testing
- dupilumab
- Where
- 13 sites in United States
- Volunteers
- 20 people
- Sponsor
- Regeneron Pharmaceuticals
Allergy
A Trial of the ALK Grass Tablet in Subjects With Hayfever
This trial is performed to assess the efficacy and safety of the ALK Grass tablet for treatment of grass pollen induced rhinoconjunctivitis (hayfever).
- Trial name
- NCT00227279
- Testing
- ALK Grass tablet
- Where
- Denmark
- Volunteers
- 634 people
- Sponsor
- ALK-Abelló A/S
Histamine Responsive Allergy Patients
The Evaluation of Bepreve on the Measurement of Wheal and Flare Response From Histamine Skin Prick Testing
To evaluate the effect of BEPREVE compared to a REFRESH Tears Lubricant eye drop on the measurement of the wheal and flare from histamine skin prick testing.
- Trial name
- NCT01128556
- Testing
- Bepreve, Refresh Tears
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- North Texas Institute for Clinical Trials
Rhinitis, Allergic, Rhinoconjunctivitis
Efficacy and Safety Evaluation of the Treatment of Allergy Against Cupressaceae and Grasses.
A Randomized, Double-Blinded, Placebo-Controlled, Prospective, Multicenter Clinical Trial to Evaluate the Efficacy and Safety of Subcutaneous Immunotherapy in Patients With Rhinitis/Rhinoconjunctivitis With or Without Mild to…
- Conditions
- Rhinitis, Allergic, Rhinoconjunctivitis, Asthma, Allergic
- Trial name
- NCT04898283
- Testing
- 10,000 MG01 +10,000 T521, 30,000 MG01 +10,000 T521
- Where
- 27 sites in Spain
- Volunteers
- 180 people
- Sponsor
- Inmunotek S.L.
Conjunctivitis, Seasonal Allergic, Conjunctivitis, Giant Papillary
A Study to Evaluate the Safety and Efficacy of Lotemax Ophthalmic Suspension 0.5%
The objective of this study is to identify any adverse events or adverse drug reactions through post-marketing surveillance under routine clinical practice
- Conditions
- Conjunctivitis, Seasonal Allergic, Conjunctivitis, Giant Papillary, Inflammation
- Trial name
- NCT01437982
- Testing
- Loteprednol Etabonate, Prednisolone Acetate 1% Oph Susp
- Where
- South Korea
- Volunteers
- 140 people
- Sponsor
- Bausch & Lomb Incorporated
Atopic Disease (Including Allergic Conjunctivitis)
A Multi-Center Study Evaluating the Safety of AC-170 0.24%
The purpose of this study is to evaluate the safety of AC-170 0.24% used twice daily in Healthy Adult Subjects and in Pediatric subjects with a history or family history of atopic disease (including allergic conjunctivitis).
- Trial name
- NCT02132169
- Testing
- Drug: AC-170 0.24%, AC-170 0%
- Where
- United States
- Volunteers
- 512 people
- Sponsor
- Aciex Therapeutics, Inc.
Allergic Rhinitis
Two Formulations and Concentrations of Epinastine Nasal Spray Versus Azelastine Nasal Solution for Allergic Rhinitis
The objectives of this study were to: Examine the tolerability of two formulations and two dose concentrations of epinastine. Select formulation(s) of epinastine for future studies by evaluating the individual sensory attribute…
- Trial name
- NCT01382654
- Testing
- epinastine 0.1%, epinastine 0.1% with taste masking agent, epinastine 0.2%
- Volunteers
- 131 people
- Sponsor
- Merck Sharp & Dohme LLC
Rhinitis
Singulair Use in Non-Allergic Rhinitis Eosinophil Syndrome (NARES)
The purpose of this trial is to determine if patients with NARES treated with montelukast (Singulair) will have improved nasal symptom scores and reduced nasal eosinophils.
- Trial name
- NCT00406094
- Testing
- montelukast
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Bernstein, Jonathan A., M.D.
Allergic Rhinitis
Topical ASP-1001 (Contrast Media Formulation) and the Acute Response to Nasal Allergen Challenge (NAC)
The purpose of this study is to see whether ASP-1001 when given as a nasal spray is safe and can reduce the signs and symptoms of allergic rhinitis (hayfever) following nasal challenge with antigen.
- Trial name
- NCT00791102
- Testing
- ASP-1001 nasal spray
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Chicago
Seasonal Allergic Rhinitis
Study of the Effect of SCH 900538 on Congestion in Subjects With Seasonal Allergic Rhinitis (Study P05031)(COMPLETED)
This study is to evaluate the effectiveness of a new drug on congestion in subjects with seasonal allergic rhinitis. This effect will be compared to placebo and to the decongestant, pseudoephedrine.
- Trial name
- NCT00673062
- Testing
- SCH 900538, Pseudoephedrine
- Volunteers
- 265 people
- Sponsor
- Merck Sharp & Dohme LLC