Clinical trials: Allergic Diseases
Type I Hypersensitivity
Induction of Immunogenicity With Different Doses of TreeMATA in Subjects Allergic to Tree Pollen
Tree MATA (modified pollen allergen tyrosine adsorbate) has been developed to provide pre-seasonal specific immunotherapy for patients with hypersensitivity to tree (birch, alder, and hazel) pollen.
- Trial name
- NCT00113750
- Testing
- TreeMATA MPL
- Where
- 10 sites in United States
- Volunteers
- 70 people
- Sponsor
- Allergy Therapeutics
Seasonal Allergic Rhinitis
This Study Contains an Active Drug Treatment Group With Mometasone Furoate Nasal Spray and a Placebo (Dummy) Treatment Group for Seasonal Allergic Rhinitis (SAR). (Study P05073)(COMPLETED)
The purpose of this study is to evaluate how well mometasone furoate nasal spray (MFNS) works to relieve SAR symptoms compared to Placebo when symptoms are induced in a chamber setting.
- Trial name
- NCT00491504
- Testing
- Mometasone Furoate Nasal Spray
- Volunteers
- 310 people
- Sponsor
- Organon and Co
Perennial Allergic Rhinitis
The Confirmatory Study of TAU-284 in Pediatric Patients With Perennial Allergic Rhinitis
The objectives of this study are: to confirm the superiority of TAU-284 over placebo after two weeks of administration to pediatric patients with perennial allergic rhinitis and to investigate safety of TAU-284.
- Trial name
- NCT01861522
- Testing
- Bepotastine besilate
- Where
- 2 sites in Japan
- Volunteers
- 473 people
- Sponsor
- Tanabe Pharma Corporation
Allergic Conjunctivitis
Patient Perception Study for AL-4943A
To evaluate patient perceptions of Al-4943 in subjects with allergic conjunctivitis previously treated with a topical ocular anti-allergy leukotriene-release inhibitor medication.
- Trial name
- NCT01294969
- Testing
- AL-4943A
- Where
- South Korea
- Volunteers
- 47 people
- Sponsor
- Alcon Research
Allergic Rhinitis
A Study to Evaluate the Safety of Combination Montelukast/Loratadine in Mexican Participants With Allergic Rhinitis (MK-0476A-484)
The purpose of this study is to assess the safety and tolerability of montelukast 10 mg/loratadine 10 mg versus placebo in Mexican participants with allergic rhinitis.
- Trial name
- NCT01673620
- Testing
- Montelukast 10 mg/loratadine 10 mg
- Volunteers
- 69 people
- Sponsor
- Organon and Co
Asthma
Efficacy and Safety Study of QAW039 in Patients With Severe Asthma Inadequately Controlled With Standard of Care Asthma Treatment.
This study aimed to determine the efficacy and safety of QAW039 150 mg and QAW039 450 mg, compared with placebo, when added to GINA (Global Initiative for Asthma) steps 4 and 5 standard-of- care (SoC) asthma therapy (GINA 2016)…
- Trial name
- NCT02555683
- Testing
- QAW039
- Where
- 234 sites in United States, Argentina and 25 more
- Volunteers
- 894 people
- Sponsor
- Novartis Pharmaceuticals
Allergic Rhinitis
Fexofenadine (Allegra®) in Healthy Adults Who Have Been Identified as Slow Metabolizers for Desloratadine
To evaluate the single-dose and steady-state pharmacokinetics of desloratadine and fexofenadine in desloratadine slow metabolizers.
- Trial name
- NCT00636870
- Testing
- Fexofenadine
- Where
- United States
- Volunteers
- 220 people
- Sponsor
- Sanofi
Rhinitis, Allergic, Perennial
Perennial Allergic Rhinitis In Pediatric Subjects
To assess the safety of long-term use of cetirizine dry syrup in children with perennial allergic rhinitis.
- Trial name
- NCT00257595
- Testing
- Cetirizine Dry Syrup
- Volunteers
- 30 people
- Sponsor
- GlaxoSmithKline
Seasonal Allergic Rhinitis, Seasonal Allergic Conjunctivitis
Safety and Efficacy of Ectoin Allergy Nasal Spray and Ectoin Allergy Eye Drops in the Treatment of Seasonal Allergic Rhinitis (SAR) in Children and Adolescents
Ectoin acts on membranes by forming an Ectoin-Hydro-Complex therewith providing a protection against external agents like aeroallergens.
- Trial name
- NCT01342601
- Testing
- ect4allergy Nasal Spray (ANS01) and Eye Drops (AAT01)
- Where
- 8 sites in Germany
- Volunteers
- 72 people
- Sponsor
- Bitop AG
Peanut Allergy
A Study to Evaluate Safety, Tolerability and Immune Response in Adults Allergic to Peanut After Receiving Intradermal or Intramuscular Administration of ASP0892 (ARA-LAMP-vax), a Single Multivalent Peanut (Ara h1, h2, h3) Lysosomal Associated Membrane Protein DNA Plasmid Vaccine
The purpose of this study is to evaluate the safety and tolerability of ASP0892 after intradermal or intramuscular injection in adults with peanut allergy.
- Trial name
- NCT02851277
- Testing
- ASP0892 Intradermal, ASP0892 Intramuscular
- Where
- 8 sites in United States
- Volunteers
- 31 people
- Sponsor
- Astellas Pharma Global Development, Inc.
Ocular Itching, Ocular Allergy
Efficacy and Safety of PRO-118 Ophthalmic Solution in Allergic Conjunctivitis
The purpose of this study is to evaluate the efficacy and safety of four doses of PRO-118 ophthalmic solution ophthalmic solution compared with placebo, for the treatment of seasonal (SAC) and perennial (PAC) allergic…
- Conditions
- Ocular Itching, Ocular Allergy, Seasonal Allergic Conjunctivitis, Perennial Allergic Conjunctivitis
- Trial name
- PRO-118 (NCT01541904)
- Testing
- PRO-118 Ophthalmic Solution 0.015%, PRO-118 Ophthalmic Solution 0.015 %, PRO-118 Ophthalmic Solution 0.020 %
- Where
- 2 sites in Mexico
- Sponsor
- Laboratorios Sophia S.A de C.V.
Allergic Rhinitis
Single Dose Crossover Study of Patient Preference for Unscented Nasonex® Nasal Spray Versus Scented Flonase® Nasal Spray (Study P04207)
This was a one-day single dose trial conducted to compare patient's preference for Nasonex® (mometasone) versus Flonase® nasal spray. Each patient was randomized to take one dose (2 sprays in each nostril) of Nasonex or Flonase.
- Trial name
- NCT00817050
- Testing
- Mometasone Furoate Nasal Spray, fluticasone nasal spray
- Volunteers
- 100 people
- Sponsor
- Organon and Co
Rhinitis
Intranasal SB-705498 in Allergic Rhinitis (AR) Patients
This study is designed to look at the affect of SB-705498 on allergic rhinitis symptoms induced by an allergen chamber challenge.
- Trial name
- NCT01424397
- Testing
- SB-705498, FP
- Where
- Austria
- Volunteers
- 70 people
- Sponsor
- GlaxoSmithKline
Allergic Rhinitis
Omnaris Versus Levocetirizine Phase 4 Study
This i a comparison of the efficacy ciclesonide nasal spray and levocetirizine, alone and in combination.
- Trial name
- NCT01430260
- Testing
- Ciclesonide, Levocetirizine, Ciclesonide & Levocetirizine
- Where
- South Korea
- Volunteers
- 349 people
- Sponsor
- Handok Inc.
Allergic Asthma, Allergy to House Dust
Validation of Strasbourg Environmental Exposure Chamber ALYATEC in Mite Allergic Subjects With Asthma
This is a randomized, double blind, cross-over study designed to determine the concentration of airborne house dust mite allergen inducing bronchial response in asthmatic subjects allergic to mite, during allergen exposures in…
- Conditions
- Allergic Asthma, Allergy to House Dust, Allergy
- Trial name
- NCT04663880
- Testing
- Exposure to three concentrations of HDM allergen in EEC, Exposure to a single concentration of HDM allergen in EEC
- Where
- France
- Volunteers
- 27 people
- Sponsor
- Alyatec
Seasonal Allergic Rhinitis
A Study to Evaluate the Safety and Effectiveness of a Nasal Spray to Treat Seasonal Allergies
The purpose of this study is to determine if two allergy medications (azelastine and fluticasone) are more effective than placebo or either medication alone (azelastine or fluticasone)
- Trial name
- NCT00660517
- Testing
- MP29-02, azelastine Hcl, fluticasone propionate
- Where
- 7 sites in United States
- Volunteers
- 607 people
- Sponsor
- Meda Pharmaceuticals
Food Hypersensitivity, Hypersensitivity
Peanut Allergy Vaccine Study in Healthy and Peanut-allergic Adults
The purpose of this study is to evaluate the safety and side effects of a study product that contains recombinant modified peanut proteins (EMP-123) in healthy and peanut-allergic participants. This is a first in human study.
- Conditions
- Food Hypersensitivity, Hypersensitivity, Immediate Hypersensitivity, Peanut Hypersensitivity
- Trial name
- NCT00850668
- Testing
- E. Coli-Encapsulated, Recombinant Modified Peanut Proteins Ara h 1, Ara h 2, and Ara h 3
- Where
- 2 sites in United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Allertein Therapeutics, LLC
Seasonal Allergic Rhinitis
A Study to Evaluate the Safety and Efficacy of a Nasal Spray to Treat Seasonal Allergies
The Purpose of this study is to evaluate the safety and efficacy of MP03-36 (0.15% azelastine hydrochloride)at dosages of 2 sprays per nostril once daily and 2 sprays per nostril twice daily in patients with seasonal allergic…
- Trial name
- NCT01368445
- Testing
- azelastine hydrochloride 0.15% Nasal Spray, Azelastine 0.1%, Nasal Spray
- Where
- 30 sites in United States
- Volunteers
- 617 people
- Sponsor
- Meda Pharmaceuticals
Allergic Rhinitis
Observational Study to Evaluate the Actual Use and Effectiveness of Dymista® Nasal Spray in Asian Patients
Gathering knowledge on the use of Dymista® in Asian patients who receive Dymista® for the first time in routine clinical practice
- Trial name
- NCT05158972
- Testing
- Dymista
- Where
- 33 sites in Hong Kong, Malaysia and 2 more
- Volunteers
- 924 people
- Sponsor
- Mylan Inc.
Rhinitis, Allergic, Seasonal
Effects of Loratadine/Montelukast vs Pseudoephedrine and Placebo in Patients With Seasonal Allergic Rhinitis (Study P04095) (COMPLETED)
This is a Phase 3, randomized, parallel-group, multicenter, double-dummy, double-blind study with a screening period. Subjects will receive one of the following three treatment groups for 15 days: loratadine 10 mg/montelukast 10…
- Trial name
- NCT00319995
- Testing
- loratadine; montelukast
- Volunteers
- 1,095 people
- Sponsor
- Organon and Co
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