Clinical trials: Allergic Rhinitis (Disorder)
Allergic Rhinitis, Allergic Rhinoconjunctivitis
Study With High Dose PURETHAL Mites in Allergic Rhinitis/Rhinoconjunctivitis Patients
The aim of the study is to establish the maximum tolerated dose of PURETHAL Mites that is achieved by 90% of the patients with less than 20% of the injections giving rise to a swelling of > 5 cm and the optimal regimen to reach…
- Trial name
- NCT00973453
- Testing
- PURETHAL Mites 20,000 AUeq/ml
- Where
- 6 sites in Germany
- Volunteers
- 48 people
- Sponsor
- HAL Allergy
Allergic Rhinitis, Rhinosinusitis Chronic
Treatment of Allergic Rhinitis and Chronic Polypous Rhinosinusitis With Olfactory Mucosa-derived Mesenchymal Stem Cells
Treatment of patients with allergic rhinitis and chronic polypous rhinosinusitis with olfactory mucosa-derived mesenchymal stem cells
- Trial name
- NCT05167552
- Testing
- Olfactory mucosa-derived mesenchymal stem cells, Standard treatment of type Allergic Rhinitis according to the clinical protocols, Standard treatment of type Chronic Polypous Rhinosinusitis according to the clinical protocols
- Volunteers
- 60 people
- Sponsor
- Institute of Biophysics and Cell Engineering of National Academy of Sciences of Belarus
Seasonal Allergic Rhinitis
Effect of a Probiotic on Seasonal Allergic Rhinitis Symptoms
The purpose of the current study is to evaluate the efficacy of administering a probiotic in adult human subjects suffering from allergic rhinitis during seasonal grass pollen exposure.
- Trial name
- NCT01653652
- Testing
- Probiotic, Maltodextrin
- Where
- Germany
- Volunteers
- 131 people
- Sponsor
- Société des Produits Nestlé (SPN)
Perennial Allergic Rhinitis
Children, Perennial Allergic Rhinitis (PAR), l-t Growth
The purpose of this study is to compare the effect of Rhinocort nasal spray with placebo on growth in children with perennial allergic rhinitis over 12 months.
- Trial name
- NCT00641212
- Testing
- Budesonide
- Volunteers
- 209 people
- Sponsor
- AstraZeneca
Asthma, Allergic Rhinitis
Assessment of Oxidative Stress Markers in the Upper and Lower Airways of Atopic Children Treated With Nebulized Beclomethasone
Although it is well known that the presence of uncontrolled inflammation in upper airways may compromise the control of asthma and may favor the progression of asthma toward more severe grades of disease, few studies addressed…
- Trial name
- NCT01113489
- Testing
- beclomethasone dipropionate
- Where
- Italy
- Volunteers
- 32 people
- Sponsor
- Fondazione C.N.R./Regione Toscana "G. Monasterio", Pisa, Italy
Allergic Rhinitis Due to Allergens
Dymista in Chinese Adolescents
The purpose of this study is to determine if the investigational drug product ("study drug"), Dymista (azelastine hydrochloride and fluticasone propionate) nasal spray is safe and effective in the treatment of allergic rhinitis…
- Trial name
- NCT07597473
- Testing
- Treatment with 137 µg azelastine hydrochloride and 50 μg of fluticasone propionate
- Where
- 14 sites in China
- Volunteers
- 100 people
- Sponsor
- Viatris Inc.
Rhinitis
Efficacy and Safety Study of Nasacort in Chronic Non Allergic and Non Infectious Rhinitis in Adults
To demonstrate the superiority of the clinical efficacy of 12 weeks' treatment with Nasacort versus placebo in adult patients presenting with Chronic Non Allergic and Non Infectious Rhinitis
- Trial name
- RhiCNANI (NCT00344942)
- Testing
- triamcinolone acetonide
- Where
- France
- Volunteers
- 77 people
- Sponsor
- Sanofi
Rhinitis, Allergic
Study on the Mechanism of ZhenQiFuZheng in the Treatment of Allergic Rhinitis Based on Intestinal Flora and Metabolites
ZhenQi FuZheng granules has been used to improve the immune function of human body, protect the bone marrow and adrenal cortex function and promote the recovery of positive function in traditional Chinese medicine care…
- Trial name
- NCT06427577
- Testing
- ZhenQi FuZheng granules (ShiDaiYangGuang)
- Where
- China
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- The First Affiliated Hospital with Nanjing Medical University
Allergic Rhinitis With Asthma
Efficacy and Safety of Yiqi Wenyang Sanhan Formula Combined With Acupoint Application in Patients With Combined Allergic Rhinitis and Asthma Syndrome During Remission and Yang-Deficiency Syndrome
Allergic rhinitis-asthma syndrome is a clinical comorbid condition involving both upper and lower airway allergic inflammation, reflecting the concept of "one airway, one inflammatory response." Epidemiological studies have…
- Trial name
- NCT07540351
- Testing
- Yiqi Wenyang Sanhan Formula Combined with Acupoint Application
- Volunteers
- 188 people
- Sponsor
- Beijing Daxing District Hospital of Integrated Chinese and Western Medicine
Seasonal Allergic Rhinitis
Phase I/IIa Study on Chitin Microparticles in Subjects Suffering From Allergic Rhinitis
Chitin microparticles (CMP) has been demonstrated in animal studies that have modelled allergic rhinitis to be effective against a wide range of common respiratory allergens. It is an immuneenhancer.
- Trial name
- NCT00443495
- Testing
- Chitin microparticles by nasal route
- Volunteers
- 24 people
- Sponsor
- CMP Therapeutics Ltd
Allergic Rhinitis
Implementation of an Allergic Rhinitis Severity Questionnaire in ENT Consultations
Allergic rhinitis is a very common condition (affecting 1 in 5 people in Europe) and a costly one for society (direct and indirect costs).
- Trial name
- QSRA-ORL (NCT07315945)
- Where
- France
- Volunteers
- 30 people
- Sponsor
- University Hospital, Strasbourg, France
Rhinitis, Allergic, Rhinoconjunctivitis
Efficacy and Safety Evaluation for the Treatment of Allergy Against Grass and Olive Pollen
Prospective, multicenter, randomized, double-blind, placebo-controlled clinical trial of efficacy and safety with subcutaneous immunotherapy in patients with mild to moderate rhinitis / rhinoconjunctivitis with or without mild to…
- Conditions
- Rhinitis, Allergic, Rhinoconjunctivitis, Asthma, Allergic
- Trial name
- NCT04891237
- Testing
- 10,000 MG01 + 10,000 T517, 30,000 MG01 + 10,000 T517
- Where
- 32 sites in Spain
- Volunteers
- 180 people
- Sponsor
- Inmunotek S.L.
Nonallergic Irritant Rhinitis
Intranasal Capsaicin Treatment for Non-Allergic Irritant Rhinitis
The proposed study seeks to investigate the effect of intranasal capsaicin treatment in patient with Non-allergic irritant rhinitis (NAIR), as well as evaluate optical rhinometry (ORM) as a means to quantify symptomatic…
- Trial name
- NCT02493257
- Testing
- Capsaicin
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Rhinitis, Allergic, Perennial
Comparator Study Evaluating Patient Experience And Preference Of FFNS vs. FPNS
The purpose of this replicate study to FFU105924 is to provide data on subject preference of FFNS as compared with FPNS.
- Trial name
- NCT00519636
- Testing
- FPNS, FFNS
- Where
- 28 sites in United States
- Volunteers
- 360 people
- Sponsor
- GlaxoSmithKline
Rhinitis, Allergic, Perennial
A Study of GW685698X for the Treatment Of Perennial Allergic Rhinitis in Adolescents and Adults
The purpose of this study is to assess the effect of an aqueous nasal spray investigational compound compared to placebo on the hypothalamic pituitary adrenocortical (HPA) axis system in adolescents and adults 12 to 65 years of…
- Trial name
- NCT00116818
- Testing
- GW685698X aqueous nasal spray
- Where
- 2 sites in United States, Canada
- Volunteers
- 90 people
- Sponsor
- GlaxoSmithKline
Seasonal Allergic Rhinitis
Evaluation of the Beneficial Effects of a Nasal Spray of Resveratrol in Children With Seasonal Allergic Rhinitis
The aim of this study is to evaluate whether treatment with a nasal spray based on resveratrol has some benefit in patients with seasonal allergic rhinitis, mild, moderate, or severe.
- Trial name
- NCT02130440
- Testing
- Resveratrol nasal spray
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- University of Campania Luigi Vanvitelli
Rhinitis, Allergic, Perennial, Rhinitis, Allergic, Seasonal
Effect of a 10,000 EU Dose of Endotoxin in Allergic and Mildly Asthmatic Adults
The purposes of this pilot safety study are to identify a dose of inhaled Clinical Center Reference Endotoxin (CCRE) that is well tolerated by allergic subjects that induces measurable increases in neutrophil content of induced…
- Conditions
- Rhinitis, Allergic, Perennial, Rhinitis, Allergic, Seasonal, Asthma
- Trial name
- NCT00839189
- Testing
- Clinical Center Reference Endotoxin (CCRE)
- Where
- United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Allergic Rhinitis
Efficacy and Safety of Xinyi Powder in Patients With Allergic Rhinitis and the Lung Deficiency and Cold Syndrome
By observing the improvement of Xinyi Powder powder and simulated agent on the symptoms, symptom and sign scores, nasal symptom VAS scores, and quality of life of patients with allergic rhinitis due to lung deficiency and cold…
- Trial name
- NCT07899515
- Testing
- Xinyi Powder
- Where
- 2 sites in China
- Volunteers
- 228 people
- Sponsor
- Nanjing University of Traditional Chinese Medicine
Asthma, Allergic Rhinitis
Effects of Lipoic Acid on Oxidative, Inflammatory and Functional Markers in Asthmatic Patients
The aim of the study is to use the antioxidant and antiinflammatory effects of lipoic acid to improve the quality of life of patients with asthma.
- Trial name
- NCT01221350
- Testing
- Lipoic acid
- Where
- 2 sites in Mexico
- Volunteers
- 55 people
- Sponsor
- Centro Universitario de Ciencias de la Salud, Mexico
Allergic Rhinitis
Study of Stapokibart Injection in Patients With Allergic Rhinitis
This study is a Randomized, Double-blind, Placebo-controlled phase II clinical study evaluating the efficacy and safety of Stapokibart injection in patients with allergic rhinitis.
- Trial name
- MIZAR (NCT06525597)
- Testing
- Stapokibart Injection
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Keymed Biosciences Co.Ltd
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