Clinical trials: Allergic Rhinitis (Disorder)
Allergic Rhinitis
Study of Yupingfeng Powder Treating Allergic Rhinitis (AR)
Rhinitis is broadly defined as inflammation of the nasal mucosa. It is a common disorder that affects up to 40% of the population.
- Trial name
- RCMARb (NCT06608017)
- Testing
- Chinese Herbal Medicine granules
- Where
- Hong Kong
- Volunteers
- 140 people
- Sponsor
- Chinese University of Hong Kong
Mite Allergy, Rhinitis, Allergic
Comparative Evaluation of Safety and Immune Activity of New Immunotherapeutic Agents for HDM Allergic Rhinitis Patients
When administering clinical trial drugs to patients with house dust mite allergic rhinitis, safety/tolerance is comparatively evaluated as the primary outcome, and symptom improvement and immune activity of the disease are…
- Conditions
- Mite Allergy, Rhinitis, Allergic, House Dust Mite Rhinitis
- Trial name
- NCT05525650
- Testing
- House Dust Mite Extract, Dermatophagoides Farinae
- Where
- South Korea
- Volunteers
- 54 people
- Sponsor
- RAPHAS
Rhinitis, Allergic, Seasonal
7 Day Study of Mast Cell Inhibitor, R926112, in Patients With Symptomatic Seasonal Allergic Rhinitis
This is a study of the effectiveness and safety of a new nasal spray for the relief of the symptoms of seasonal allergies. The agents being compared are: R926112 (a novel anti-allergy medicine), Beconase (beclomethasone…
- Trial name
- NCT00115089
- Testing
- R926112, Beclomethasone dipropionate
- Volunteers
- 375 people
- Sponsor
- Rigel Pharmaceuticals
Atopy, Atopic Dermatitis
Inhibitory Receptors in Eosinophils of Atopic Subjects
The purpose of this study is to analyze the expression and activity of inhibitory molecules on eosinophils obtained from allergic subjects.
- Conditions
- Atopy, Atopic Dermatitis, Asthma, Allergic Rhinitis
- Trial name
- NCT01489293
- Where
- Israel
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Meir Medical Center
House Dust Mite Allergy
Safety and Efficacy of House Dust Mite Allergen Extract in the Treatment of Allergic Rhinoconjunctivitis
The trial is performed to assess efficacy and safety of Novo-Helisen Depot in allergic Rhinoconjunctivitis
- Trial name
- NCT00263549
- Testing
- House dust mite Novo Helisen Depot
- Where
- Germany
- Sponsor
- Allergopharma GmbH & Co. KG
Seasonal Allergic Rhinitis
A Study to Evaluate the Safety and Efficacy of Two Nasal Sprays to Treat Seasonal Allergies
The purpose of this study was to determine if two allergy medications are more effective than placebo.
- Trial name
- NCT00720278
- Testing
- 0.15% azelastine hydrochloride 1644 mcg daily, 0.1% azelastine hydrochloride 1096 mcg daily
- Where
- 29 sites in United States
- Volunteers
- 526 people
- Sponsor
- Meda Pharmaceuticals
Rhinitis
Effect Of Probiotic Lactobacillus Paracasei Lp-33 For The Management Of Rhinitis In People Sensitized To Allergens
The aim of the study is to show an improvement of quality of life on the 5th week of product consumption (probiotic Lactobacillus paracasei LP-33)(as assessed by RQLQ global score) in subjects with persistent allergic rhinitis…
- Trial name
- BionAtlanta (NCT01096615)
- Testing
- Lactobacillus paracasei LP-33
- Where
- 125 sites in France
- Volunteers
- 500 people
- Sponsor
- Merck Medication Familiale
Allergic Rhinitis
Intranasal Steroids and Oxymetazoline in Allergic Rhinitis
We hypothesize that once daily use of oxymetazoline will not cause significant rhinitis medicamentosa and that the combination of fluticasone furoate plus oxymetazoline leads to faster relief of nasal congestion secondary to…
- Trial name
- NCT00584987
- Testing
- Fluticasone furoate, Oxymetazoline
- Where
- United States
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- University of Chicago
Rhino Sinusitis
Safety Evaluation of Intranasal Use of DSM 32444 Postbiotic in Humans
Rhinitis is a type of upper respiratory infection with a common nasal pathology especially in Southeast Asia, which is characterized by the presence of one or more of the following symptoms: itchy nose, sneezing, runny nose, and…
- Trial name
- NCT05984004
- Testing
- 0.9% NaCl isotonic saline solution, Bacillus subtilis DSM32444, inactivated
- Where
- Vietnam
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Huro Biotech Joint Stock Company
Allergic Rhinitis, Allergic Conjunctivitis
An Allergen BioCube (ABC) Study Evaluating the Efficacy of Fluticasone Propionate Nasal Spray Compared to Placebo
The purpose of this study is to evaluate the onset of action of fluticasone propionate nasal spray compared to placebo nasal spray in reducing nasal allergic signs and symptoms following ragweed exposure in the Allergen BioCube…
- Trial name
- NCT01439815
- Testing
- Fluticasone Propionate Nasal Spray, Saline Nasal Spray
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- ORA, Inc.
Type I Hypersensitivity
Follow-up Investigation of Efficacy of Ragweed MATAMPL,and Placebo in Patients With Ragweed-induced Seasonal Allergic Rhinitis
Ragweed MATAMPL has been developed to provide pre-seasonal specific immunotherapy for patients with hypersensitivity to ragweed pollen (hay fever).
- Trial name
- NCT00325338
- Testing
- Ragweed MATAMPL
- Where
- Canada
- Volunteers
- 100 people
- Sponsor
- Allergy Therapeutics
Chronic Rhinosinusitis (Diagnosis), Allergic Rhinosinusitis
Effectiveness of Mometasone Nasal Irrigation for Chronic Rhinosinusitis
Chronic rhinosinusitis (CRS) affects up to 12.5% of the US population and has a significant disease burden. The recommended medical management of CRS includes large-volume, low-pressure saline lavage, systemic antibiotics, and…
- Conditions
- Chronic Rhinosinusitis (Diagnosis), Allergic Rhinosinusitis, Chronic Eosinophilic Rhinosinusitis
- Trial name
- NCT03705793
- Testing
- Mometasone Furoate Nasal Irrigation, Mometasone Nasal Spray
- Where
- 2 sites in United States
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Food Allergy, Asthma
Assessing Risk of Food Insecurity Within Households of Children With Food Allergy
Our central hypothesis is that dietary limitations introduced by food allergy will contribute to increased food insecurity in households with food allergic children when compared to food insecure households without food allergic…
- Conditions
- Food Allergy, Asthma, Allergic Rhinitis, Atopic Dermatitis
- Trial name
- NCT01897506
- Where
- United States
- Volunteers
- 650 people
- Sponsor
- Arkansas Children's Hospital Research Institute
Viral Infections of the Upper Respiratory Tract
Comparison Between Dexchlorpheniramine and Dexchlorpheniramine/Pseudoephedrine/Guaifenesin in Respiratory Infections
Patients with allergic rhinitis frequently present exacerbation of the atopic symptoms during viral infections of the upper respiratory tract.
- Trial name
- NCT01085721
- Testing
- Dexchlorpheniramine, pseudoephedrine, guaifenesin, Dexchlorpheniramine
- Volunteers
- 170 people
- Sponsor
- Mantecorp Industria Quimica e Farmaceutica Ltd.
Asthma, House Dust Mite Allergy
Safety Study of Sublingual Immunotherapy Tablets of House Dust Mite Allergen Extracts
The purpose of this study is to investigate the safety of different doses of sublingual tablets of house dust mite allergen extracts in adults with house dust mite-associated allergic asthma.
- Trial name
- NCT01608243
- Testing
- SLIT tablets of house dust mite allergen extracts
- Where
- France
- Volunteers
- 94 people
- Sponsor
- Stallergenes Greer
Allergic Rhinitis
Phase 2 Study in Adults Sensitized to Short Ragweed
The purpose of this study is to identify an effective dose of allergen-specific immunotherapy for short ragweed (Ambrosia artemisiifolia) administered by an oral/sublingual route.
- Trial name
- NCT00670384
- Testing
- Standardized Allergenic Extract, Short Ragweed (Ambrosia artemisiifolia)
- Sponsor
- Antigen Laboratories, Inc.
Local Allergic Rhinitis
Subcutaneous Immunotherapy With Dermatophagoides Pteronyssinus in Local Allergic Rhinitis
To evaluate the efficacy of an extract of Dermatophagoides pteronyssinus versus placebo in the treatment of local allergic rhinitis.
- Trial name
- ECRL1 (NCT02123316)
- Testing
- Pangramin Plus D. pteronyssinus
- Where
- Spain
- Volunteers
- 36 people
- Sponsor
- Miguel Blanca Gomez
Atopic Dermatitis, House Dust Mite Allergy
Skin Responses and T Cell Immunology After House Dust Mite Exposure in Sensitized Atopic Dermatitis Patients
The present study investigates the reaction of the skin upon exposure to house dust mite (HDM) in patients with atopic dermatitis who have antibodies against HDM in the blood.
- Trial name
- CODES (NCT05019209)
- Testing
- House Dust Mite Allergen, Allergen-free air
- Where
- 2 sites in Germany
- Volunteers
- 23 people
- Sponsor
- Fraunhofer-Institute of Toxicology and Experimental Medicine
Seasonal Allergic Rhinitis
Bepotastine Besilate Nasal Sprays in the Treatment of Seasonal Allergic Rhinitis (SAR)
This study will examine dose ranging characteristics of bepotastine besilate nasal spray compared to placebo nasal spray in 600 male or female subjects 12 years of age and older with active seasonal allergic rhinitis (SAR) and a…
- Trial name
- NCT01753739
- Testing
- Bepotastine besilate
- Where
- United States
- Volunteers
- 617 people
- Sponsor
- Bausch & Lomb Incorporated
Patients
The Effects of Sphenopalatine Ganglion Acupuncture in Patients With Seasonal Allergic Rhinitis
Sphenopalatine ganglion (SPG)-acupuncture has been shown to exhibit distinct effects in treatment of nasal inflammatory disease.
- Trial name
- NCT03282630
- Testing
- Sphenopalatine ganglion acupuncture
- Where
- China
- Volunteers
- 150 people
- Sponsor
- Beijing Tongren Hospital
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