Clinical trials: Allergic Rhinitis (Disorder)
Allergic Rhinitis, Asthma
Assessment of Suppression of Cutaneous Allergic Responses and Pruritis by Topical Minocycline
Adults with known respiratory allergy/asthma with known skin test sensitization will undergo repeat skin prick testing at 4 areas of both arms (bilateral forearms, bilateral upper arms).
- Trial name
- GINA3 (NCT04202263)
- Testing
- Minocycline Topical
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- State University of New York - Downstate Medical Center
Allergic Rhinitis
Intranasal Steroids and Oxymetazoline in Allergic Rhinitis
We hypothesize that once daily use of oxymetazoline will not cause significant rhinitis medicamentosa and that the combination of fluticasone furoate plus oxymetazoline leads to faster relief of nasal congestion secondary to…
- Trial name
- NCT00584987
- Testing
- Fluticasone furoate, Oxymetazoline
- Where
- United States
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- University of Chicago
Seasonal Allergic Rhinitis
This Study Contains an Active Drug Treatment Group With Mometasone Furoate Nasal Spray and a Placebo (Dummy) Treatment Group for Seasonal Allergic Rhinitis (SAR). (Study P05073)(COMPLETED)
The purpose of this study is to evaluate how well mometasone furoate nasal spray (MFNS) works to relieve SAR symptoms compared to Placebo when symptoms are induced in a chamber setting.
- Trial name
- NCT00491504
- Testing
- Mometasone Furoate Nasal Spray
- Volunteers
- 310 people
- Sponsor
- Organon and Co
Perennial Allergic Rhinitis
Post Approval Pharmacokinetic Study of Loratadine in Japanese Pediatric and Adult Patients (Study P05539)
This is a post marketing study to confirm the appropriate dose of loratadine in children by obtaining drug concentration data at multiple time points per child and adult patient, after the patient receives repeated…
- Trial name
- NCT00730912
- Testing
- loratadine
- Volunteers
- 261 people
- Sponsor
- Merck Sharp & Dohme LLC
Seasonal Allergic Rhinitis
Safety and Efficacy of Olopatadine HCl Nasal Spray in 6-11 Year Old Patients
A study to demonstrate the superiority of test article nasal spray relative to vehicle nasal spray for the treatment of seasonal allergic rhinitis for a 2 week period in patients aged 6 to 11 years with a history of seasonal…
- Trial name
- NCT00578929
- Testing
- Olopatadine Hydrochloride Nasal Spray 0.6%, Vehicle
- Where
- United States
- Volunteers
- 2,388 people
- Sponsor
- Alcon Research
Atopic Dermatitis, Allergic Rhinitis
Prevention Allergic Disease of Infant With Probiotics During Pregnancy and Neonatal Period
The purpose of this study is to determine whether childhood atopic disease decrease or not after allowing allergic mothers intake of probiotic (Lactobacillus GG) in second trimester, followed by infant intake for 6 months after…
- Conditions
- Atopic Dermatitis, Allergic Rhinitis, Asthma
- Trial name
- NCT00325273
- Testing
- Lactobacillus rhamnosus GG
- Where
- Taiwan
- Volunteers
- 180 people
- Sponsor
- Chang Gung Memorial Hospital
Allergic Rhinitis, Allergic Rhinoconjunctivitis
PURETHAL Grasses Rush Study
This study investigates the safety of two up-dosing regimen. The safety of PURETHAL Grasses will be evaluated in a rush regimen (maximum dose reached in 3 injections during 2 weeks) compared to the conventional regimen (maximum…
- Trial name
- NCT01059266
- Testing
- PURETHAL Grasses, 20.000 AUM/ml
- Where
- 11 sites in Germany
- Volunteers
- 150 people
- Sponsor
- HAL Allergy
Seasonal Allergic Rhinitis
A Study of Epinastine Nasal Spray in Subjects With Seasonal Allergic Rhinitis
The purpose of this trial is to determine the safety, efficacy and tolerability of two doses of the study drug compared to placebo for the treatment of subjects with seasonal allergic rhinitis.
- Trial name
- NCT00407927
- Testing
- Epinastine Nasal Spray
- Where
- 7 sites in United States
- Volunteers
- 571 people
- Sponsor
- Merck Sharp & Dohme LLC
Allergic Rhinitis
Comparability and Standardization of Controlled Allergen Challenge Facilities
Allergen challenge facilities have been utilized for many years in clinical drug trials studying onset of action, proof of concept, duration of action, and efficacy.
- Trial name
- NCT02543346
- Testing
- Cetirizine
- Where
- 2 sites in United States, Canada
- Volunteers
- 98 people
- Sponsor
- Queen's University
Asthma Acute, Allergic Rhinitis
Immune Nutrition in Pediatric Respiratory Allergy
Respiratory allergic diseases, namely asthma and allergic rhinitis (AR), are among the most common chronic pediatric conditions with prevalence continuing to rise over last decades and are leading healthcare costs.
- Trial name
- INAPRA (NCT07308288)
- Testing
- AllergySTOP
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- Federico II University
Allergic Rhinitis (AR)
A Phase 1 Scintigraphy Study to Assess Nasal Deposition of Ciclesonide. Using a Novel Nasal Metered Dose Inhaler
This study is an open label, single dose, single site, randomized, cross over study that will assess nasal deposition of radioactivity following nasal inhalation of a ciclesonide radiolabeled solution via a novel nasal Metered…
- Trial name
- NCT01371786
- Testing
- ciclesonide nasal aerosol, mometasone Aqueous (AQ) nasal spray
- Where
- United Kingdom
- Volunteers
- 14 people
- Sponsor
- Sumitomo Pharma America, Inc.
Seasonal Allergic Rhinitis
Vitamin D Plus Fluticasone Propionate
The objectives of this study would be to see if the addition of vitamin D to fluticasone propionate provides greater symptomatic relief in patients with seasonal allergic rhinitis compared to fluticasone propionate treatment…
- Trial name
- NCT01103934
- Testing
- Vitamin D3, Fluticasone Propionate
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- University of Chicago
Rhinitis Allergic, Rhinitis Seasonal
A Study to Visualize Multi-Symptom Allergy in Adults With Seasonal Allergic Rhinitis
This study is designed to visualize the response to use of fluticasone propionate nasal spray (Flonase Allergy Relief) to relieve facial allergy symptoms in individuals with moderate to severe seasonal allergic rhinitis (SAR).
- Trial name
- NCT07817134
- Testing
- Fluticasone propionate
- Where
- Canada
- Volunteers
- 16 people
- Sponsor
- HALEON
Rhinitis, Allergic
Efficacy and Safety of Ganciclovir Capsules in the Treatment of Refractory Moderate-to-severe Allergic Rhinitis
The goal of this clinical trial is to learn about the clinical efficacy and safety of ganciclovir (GCV) capsules in the treatment of refractory moderate-to-severe allergic rhinitis. The main questions it aims to answer are: 1.
- Trial name
- NCT06436534
- Testing
- Ganciclovir Oral Capsule, Ganciclovir Simulant Oral Capsule, Mometasone Nasal
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Allergic Asthma, Allergic Rhinitis
Effect of Montelukast on Basophils, In-vitro
Subjects with either allergic asthma or allergic rhinitis will be recruited to obtain blood. This blood will be used to be stimulated with to whatever the patient allergic.
- Trial name
- NCT00710450
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Creighton University
Seasonal Allergic Rhinitis
Comparative Safety and Efficacy of Two Steroid Treatments in the Relief of the Symptoms of Seasonal Allergic Rhinitis
To compare safety and efficacy of Perrigo's steroid drug product compared with an FDA approved steroid drug product in the treatment of subjects with seasonal allergic rhinitis.
- Trial name
- NCT02230696
- Testing
- Azelastine Hydrochloride/Fluticasone Propionate Nasal Spray
- Where
- 30 sites in United States
- Volunteers
- 951 people
- Sponsor
- Padagis LLC
Rhinitis, Allergic, Seasonal
Study of Nasal Symptom Relief and Side Effects in Hayfever Patients Treated With Aerius (Desloratadine)(P03442)
The purpose of this study was to test the effectiveness and side effects of desloratadine (Aerius) in patients with hayfever. Patients took desloratadine once a day for 15 days.
- Trial name
- NCT00805584
- Testing
- desloratadine
- Volunteers
- 311 people
- Sponsor
- Organon and Co
Allergic Rhinitis
Effects of Multiple Nasal Exposures to House Dust Mite Allergen on Nasal and Body Inflammation and Airway Sensitivity
This study will evaluate whether multiple nasal antigen challenges with dust mite allergen produces increases in nasal symptoms and local allergic inflammatory cells in the nose and the blood.
- Trial name
- NCT00513487
- Testing
- Dust mite extract, Fluticasone, Methacholine
- Where
- Australia
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Novartis
Seasonal Allergic Rhinitis
Preference for Clarinex Tablets vs. Allegra Tablets in Patients With Seasonal Allergies (Study P03179)
This was a crossover study designed to see if patients with seasonal allergy symptoms preferred Clarinex® or Allegra®. Patients were randomized to take 7 days of Clarinex or Allegra treatment, followed by a 5 to 28-day washout…
- Trial name
- NCT00794248
- Testing
- desloratadine 5 mg, fexofenadine
- Volunteers
- 122 people
- Sponsor
- Organon and Co
Rhinitis, Allergic, Nonseasonal
Nasal Irritation Study: Individual Factors in Nasal Irritant Sensitivity
This study seeks to document differences in nasal irritant sensitivity within the population. The investigators are interested in knowing whether age, gender, and allergy status (nasal allergies) predict nasal irritant…
- Trial name
- NCT00041821
- Testing
- Nasal irritation thresholds and irritant provocation
- Where
- United States
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- National Institute of Environmental Health Sciences (NIEHS)
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