Clinical trials: Allergic Rhinitis (Disorder)
Hay Fever
Safety and Efficacy Study of rEV131 in Allergic Rhinitis
The purpose of this study is to see whether rEV131 when given as a nasal spray in a single dose to each nostril is safe and can reduce the signs and symptoms of allergic rhinitis (hay fever) caused by an allergen challenge.
- Trial name
- NCT00247520
- Testing
- topical nasal rEV131
- Where
- 2 sites in United States
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- Evolutec Group
Allergic Rhinitis
RGB(Red- Green-Blue) Measurement of the Nasal Mucosal Image
The aim of this study was to evaluate the color values of the nasal mucosa, which is easily assessable by a direct, non-invasive, objective photographic measurement, for the purpose of presenting a diagnostic objective parameter…
- Trial name
- NCT03070288
- Testing
- Red-green-blue measurements of nasal mucosa image
- Where
- Turkey (Türkiye)
- Volunteers
- 146 people, healthy volunteers welcome
- Sponsor
- Bezmialem Vakif University
Perennial Allergic Rhinitis
Efficacy Study for the Symptomatic Treatment of Perennial Allergic Rhinitis With a 1 Year Safety Extension
Double-blind phase: The objective of the study was to evaluate the efficacy and safety of Bilastine 20 mg, compared to Cetirizine and placebo for the treatment of perennial allergic rhinitis.
- Trial name
- NCT01127620
- Testing
- Bilastine, Cetirizine
- Volunteers
- 650 people
- Sponsor
- Faes Farma, S.A.
Perennial Allergic Rhinitis
A Study to Evaluate the Safety and Effectiveness of a Nasal Spray to Treat Perennial Allergies
The purpose of this study is to determine if two allergy medications are more effective than placebo.
- Trial name
- NCT00712920
- Testing
- 0.15% azelastine hydrochloride, 0.1% azelastine hydrochloride
- Where
- 43 sites in United States
- Volunteers
- 581 people
- Sponsor
- Meda Pharmaceuticals
Allergic Rhinitis
Fexofenadine (Allegra®) in Healthy Adults Who Have Been Identified as Slow Metabolizers for Desloratadine
To evaluate the single-dose and steady-state pharmacokinetics of desloratadine and fexofenadine in desloratadine slow metabolizers.
- Trial name
- NCT00636870
- Testing
- Fexofenadine
- Where
- United States
- Volunteers
- 220 people
- Sponsor
- Sanofi
Seasonal Allergic Rhinitis
Rhinocort Aqua Versus Placebo and Fluticasone Propionate
The purpose of this study is to compare once daily treatment with Rhinocort against placebo and Fluticasone Propionate at reliving the nasal symptoms of seasonal allergic rhinitis.
- Trial name
- NCT00641680
- Testing
- Budesonide, Fluticasone propionate
- Volunteers
- 750 people
- Sponsor
- AstraZeneca
Non-allergic Rhinitis
Elaboration of Patient-friendly Treatment Strategy With Capsaicin Nasal Spray in Patients With Idiopathic Rhinitis
Chronic rhinitis is affecting more than 200 million people worldwide. Its prevalence is estimated to be as high as 30% of the Western population.
- Trial name
- NCT02288156
- Testing
- Capsaicin
- Where
- Belgium
- Volunteers
- 80 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
COVID-19, Allergic Rhinitis
the Relationship Between Allergic Rhinitis and the Risk of Symptom in Patients With Mild COVID-19
At present, most studies mainly focussed on severe patients, and there was no comparison of symptom differences between AR patients and healthy people with mild infection to evaluate the symptoms of AR patients during infection…
- Trial name
- NCT05753241
- Testing
- no intervention
- Where
- China
- Volunteers
- 1,100 people, healthy volunteers welcome
- Sponsor
- qinxiu zhang
Nasal Obstruction, Septal Defect
Does Batten Grafting Improve Nasal Outcomes in Septoplasty and Turbinate Reduction?
The objective of this study is to compare the effectiveness of batten grafts plus septoplasty and turbinate reduction (intervention arm) compared to septoplasty and turbinate reduction alone (control arm), both in terms of…
- Conditions
- Nasal Obstruction, Septal Defect, Allergic Rhinitis, Nasal Polyps
- Trial name
- NCT05287841
- Testing
- Batten batten graft, Septoplasty, Inferior Turbinate Reduction
- Where
- 3 sites in United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Northwell Health
Allergic Rhinitis
Allergen Challenge Chamber Study With Single Dose Intranasal GSK1004723 Compared With Placebo
This is a placebo-controlled, 3-period crossover study to assess the efficacy and safety of two single doses of an intranasal anti-histamine GSK1004723 compared with placebo in an allergen challenge chamber in male subjects with…
- Trial name
- NCT00824356
- Testing
- GSK1004723 (200mg), GSK1004723 (1000mg)
- Where
- Germany
- Volunteers
- 54 people
- Sponsor
- GlaxoSmithKline
Rhinitis
Response of Desloratadine Syrup in the Relief of Symptoms Associated With Perennial Allergic Rhinitis in Pediatric Patients (Study P04299)
Evaluate the safety and general clinical response of desloratadine syrup in the relief of symptoms associated with perennial allergic rhinitis in Indonesian pediatric patients.
- Trial name
- NCT00704769
- Testing
- Desloratadine (assigned by investigator as part of normal practice)
- Volunteers
- 591 people
- Sponsor
- Organon and Co
Mite Allergy, Dermatophagoides Farinae Allergy
Retrospective Study Evaluating the Effectiveness and Safety of Immunotherapy With Clustoid Max Forte
House dust mites are the main source of allergies in indoor environments. They are predominant in coastal areas, with the Canary Islands being the autonomous community with the highest percentage of patients with…
- Conditions
- Mite Allergy, Dermatophagoides Farinae Allergy, Dermatophagoides Pteronyssinus Allergy, Rhinitis, Allergic
- Trial name
- NCT07427576
- Testing
- Clustoid® Max Forte
- Where
- 2 sites in Spain
- Volunteers
- 140 people
- Sponsor
- Inmunotek S.L.
Allergic Rhinitis
Intralymphatic Immunotherapy for House Dust Mite, Dog, and Cat Allergy Using Tyrosine S® in Allergic Rhinitis
The investigators will perform double-blinded placebo-controlled randomized clinical trial which evaluates the efficacy and safety of allergen-specific intralymphatic immunotherapy (ILIT) for allergens including Dermatophagoides…
- Trial name
- ILIT-T (NCT02665754)
- Testing
- ILIT with extract of causal allergen, ILIT with normal saline, Rescue medication for allergic rhinitis
- Where
- South Korea
- Volunteers
- 32 people
- Sponsor
- Gachon University Gil Medical Center
Asthma; Allergic Rhinitis
Tolerability and Pharmacokinetics of CSPCHA115 Capsules in Chinese Healthy Volunteers
A randomized, single-center, double-blind, ascending multiple-dose, placebo-controlled study to evaluate the tolerability and pharmacokinetics of CSPCHA115 capsules in Chinese healthy volunteers.
- Trial name
- NCT04161547
- Where
- China
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- CSPC ZhongQi Pharmaceutical Technology Co., Ltd.
Allergic Rhinitis, Inflammation
Airway Inflammation in Children With Allergic Rhinitis and Intervention
The purpose of this study is to determine whether treating upper airway with intranasal corticosteroids in children with allergic rhinitis and no asthma may bring favors in reducing lower airway inflammation and improving small…
- Conditions
- Allergic Rhinitis, Inflammation, Respiratory Tract Diseases, Hypersensitivity
- Trial name
- NCT02352168
- Testing
- Budesonide nasal spray
- Where
- China
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Guangzhou Institute of Respiratory Disease
Allergic Rhinitis
Application of Ectoine Nasal Spray in Comparison With Cromolyn Sodium Containing Nasal Spray in Patients With Allergic Rhinitis
This is a comparative, open label, parallel group, non interventional study to further demonstrate the effectiveness and tolerability of Ectoin Allergy Nasal Spray.
- Trial name
- NCT02131038
- Testing
- Medica device, drug-like
- Where
- Germany
- Volunteers
- 50 people
- Sponsor
- Bitop AG
Perennial Allergic Rhinitis, Probiotics
the Efficacy and Safety of Probiotics eN-Lac® Capsules of Children With Perennial Allergic Rhinitis
The purpose of this study is to evaluate the efficacy and safety of probiotics eN-Lac® capsules (Lactobacillus paracasei GMNL-32) for the treatment of children with perennial allergic rhinitis(PAR).
- Conditions
- Perennial Allergic Rhinitis, Probiotics, Lactobacillus Paracasei GMNL-32 (eN-Lac®)
- Trial name
- PAR (NCT01116778)
- Testing
- eN-Lac®
- Where
- 4 sites in Taiwan
- Volunteers
- 236 people
- Sponsor
- GenMont Biotech Incorporation
Diphenhydramine Causing Adverse Effects in Therapeutic Use, Hyperthermia
Diphenhydramine and Sweating
In 2012, it was estimated that nearly 1 in 4 Canadians suffer from allergic rhinitis. To add, 78% of individuals working in predisposing environments are predicted to develop occupational rhinitis.
- Conditions
- Diphenhydramine Causing Adverse Effects in Therapeutic Use, Hyperthermia, Allergic Rhinitis, Sweating
- Trial name
- BENEXE2022 (NCT05586477)
- Testing
- Diphenhydramine
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Lakehead University
Allergic Rhinitis
Clinical Trial Of The Effectiveness Of The Product Cloratadd D (Loratadine + Pseudoephedrine Sulfate) Produced By The Laboratory EMS S/A, Compared To The Drug Claritin D Produced By Schering-Plough S/A, In Patients With Allergic Rhinitis
The primary objective of this study is to evaluate the clinical efficacy of the drug Cloratadd D ® (loratadine + pseudoephedrine sulfate - EMS S/A) compared to the drug Claritin D ® (loratadine + pseudoephedrine sulfate …
- Trial name
- NCT01055756
- Testing
- Loratadine + Pseudoephedrine sulfate
- Where
- Brazil
- Sponsor
- Azidus Brasil
Rhinitis, Allergic, Perennial
Study of Triamcinolone Acetonide on the Growth Velocity of Children, Ages 3 to 9, With Perennial Allergic Rhinitis (PAR)
The primary objective of the study was to characterize the difference in prepubescent growth velocity in children 3 to 9 years of age with perennial allergic rhinitis (PAR) treated with triamcinolone acetonide (TAA) nasal spray…
- Trial name
- NCT00449072
- Testing
- TAA-AQ, Nasacort® AQ, Claritin®
- Where
- United States
- Volunteers
- 299 people
- Sponsor
- Sanofi
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