Clinical trials: Allergic Rhinitis (Disorder)
Allergic Rhinitis
Hypothalamic-Pituitary-Adrenal (HPA)-Axis Study in Pediatric Subjects With Perennial Allergic Rhinitis (PAR)
The purpose of this study is to compare the effect of 6 weeks of treatment with beclomethasone dipropionate (BDP) nasal aerosol versus placebo on HPA-axis function, as assessed by 24-hour serum cortisol weighted mean, and to…
- Trial name
- NCT01697956
- Testing
- BDP
- Where
- 6 sites in United States
- Volunteers
- 99 people
- Sponsor
- Teva Branded Pharmaceutical Products R&D, Inc.
Seasonal Allergic Rhinitis (SAR)
Efficacy and Safety of GSP 301 Nasal Spray in Children (Aged 6 to Under 12 Years) With Seasonal Allergic Rhinitis (SAR)
Study to evaluate the efficacy, safety and tolerability of GSP 301 nasal spray (NS) compared with placebo NS in pediatric subjects (aged 6 to under 12 years) with Seasonal Allergic Rhinitis (SAR).
- Trial name
- GSP 301-305 (NCT03463031)
- Testing
- GSP 301 NS
- Where
- 32 sites in United States
- Volunteers
- 446 people
- Sponsor
- Glenmark Specialty S.A.
Rhinitis, Allergic, Perennial
Single Dosing Clinical Trial of HL151
The purpose of this study is to assess the pharmacokinetic characteristics of bepotastine after single oral administration of TALION tab, a IR formulation of bepotastine as reference drug and HL151, a SR formulation of…
- Trial name
- NCT02682745
- Testing
- HL151, TALION tab.
- Where
- South Korea
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Hanlim Pharm. Co., Ltd.
Allergic Rhinitis, Allergic Rhinoconjunctivitis
Adolescent Mite Allergy Safety Evaluation
This is a 28-day clinical trial studying the safety of the house dust mite tablet in adolescents with allergic rhinitis/rhinoconjunctivitis.
- Trial name
- AMASE (NCT04541004)
- Testing
- HDM SLIT-tablet
- Where
- 27 sites in Czechia, Germany and 1 more
- Volunteers
- 253 people
- Sponsor
- ALK-Abelló A/S
Allergic Rhinitis, Allergic Conjunctivitis
A Multicenter Study to Evaluate Safety and Efficacy of Specific Immunotherapy With Modified Allergen Extracts
This trial is performed to evaluate the safety and clinical efficacy of subcutaneous specific immunotherapy in patients suffering from seasonal allergic rhinitis/rhinoconjunctivitis.
- Trial name
- NCT01012752
- Testing
- modified allergen extract
- Where
- Germany
- Volunteers
- 150 people
- Sponsor
- Roxall Medizin
Allergic Rhinitis
Sterimar Allergic Rhinitis
The study aims to confirm the safety and performance of a hypertonic seawater-based nasal spray enriched with manganese and calcium, in relief/reduction of nasal symptoms (congestion, itchy nose, runny nose and sneezing) among…
- Trial name
- NCT05506709
- Testing
- Seawater nasal spray
- Where
- Armenia
- Volunteers
- 59 people
- Sponsor
- Church & Dwight Company, Inc.
Asthma, Seasonal Allergic Rhinitis
The Role of Pollen Starch Granules in Pollen Challenge Studies in the Fraunhofer Environmental Exposure Unit
The aim of the study is to explore the contribution of pollen starch granules to the induced symptoms and airway inflammation in patients with allergic rhinitis and mild asthma in a controlled pollen exposure(pollen challenge…
- Trial name
- NCT00209365
- Testing
- exposure to grass pollen/starch granules
- Where
- Germany
- Volunteers
- 24 people
- Sponsor
- Fraunhofer-Institute of Toxicology and Experimental Medicine
Rhinitis, Allergic, Allergy
Effect of Vitamin C on Allergy Skin Test
This study will assess the effect of taking vitamin C on allergy skin test.
- Trial name
- NCT05810233
- Testing
- Ascorbic acid 1000mg
- Where
- Malaysia
- Volunteers
- 90 people
- Sponsor
- National University of Malaysia
Seasonal Allergic Rhinitis
A Study to Evaluate the Efficacy and Safety of AK139 in Participants With Seasonal Allergic Rhinitis
This is a randomized, double-blind phase II clinical study to evaluate the efficacy and safety of AK139 in the treatment of participants with moderate to severe SAR
- Trial name
- NCT07436234
- Testing
- AK139
- Where
- China
- Volunteers
- 111 people
- Sponsor
- Akeso
Allergic Rhinitis, Nasal Congestion
Chlorpheniramine Maleate Nasal Spray for Chronic Rhinitis
Allergic rhinitis is defined as the symptoms of sneezing, nasal itching, airflow obstruction, and, mostly, clear nasal discharge caused by IgE-mediated reactions against inhaled allergens and involving mucosal inflammation driven…
- Trial name
- NCT04790487
- Testing
- CPM
- Where
- United States
- Sponsor
- Larkin Community Hospital
Allergic Rhinitis
Study to Evaluate Diphenhydramine in Children and Adolescents
To characterize the pharmacokinetics of diphenhydramine in two pediatric populations: children, ages 2 to < 12 years, and adolescents, ages 12 to < 18 years.
- Trial name
- NCT00762749
- Testing
- diphenhydramine HCl
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- Johnson & Johnson Consumer and Personal Products Worldwide
Perennial Rhinitis
Local IgE in Subjects With Allergic or Non-allergic Rhinitis
The purpose of the study is to investigate the incidence of non-allergic rhinitis on a not selected group of young students (n=100-300). Students will be selected by public posting.
- Trial name
- LISA (NCT02810535)
- Testing
- Observation
- Where
- Germany
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Johann Wolfgang Goethe University Hospital
Allergic Rhinitis
Efficacy Of Bacterial Lysate In Children With Allergic Rhinitis
This study evaluate the efficacy of Polyvalent Mechanical Bacterial Lysate (PMBL - Ismigen) to improve the clinical course of grass pollen-induced allergic rhinitis (using: TNSS, TOSS, VAS, PNIF) in children aged 5 to 17.
- Trial name
- NCT04270552
- Testing
- Ismigen
- Where
- Poland
- Volunteers
- 76 people
- Sponsor
- Medical University of Lublin
Allergy Pollen, Allergic Reaction
Juniperus Oxycedrus and Cupressus Arizonica Allergen Extracts Standardisation.
The objective of this study is to determine the biological activity of Juniperus oxycedrus and Cupressus arizonica. allergen extracts in histamine equivalent prick (HEP) units, in order to be used as in-house reference…
- Conditions
- Allergy Pollen, Allergic Reaction, Allergic Skin Reaction
- Trial name
- NCT05533385
- Testing
- Allergenic extract
- Where
- Spain
- Volunteers
- 30 people
- Sponsor
- Inmunotek S.L.
Seasonal Allergic Rhinitis
Effects of Orotic Acid Derivatives With or Without Glutathione on Allergic Rhinitis
The purpose of this study is to learn if two nutritional supplements, Orotic Acid and Glutathione will have any effect on the immune system response and if there will be any effect on the symptoms of seasonal allergies.
- Trial name
- NCT00227058
- Testing
- Orotic acid and Glutathione-(Nutritional Supplements)
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Mississippi Medical Center
Asthma, Allergic Rhinitis
Nasal Allergen Challenge in Rhinitic Subjects
Background: Nasal allergen challenge (NAC) is useful to study the pathophysiology of rhinitis, and multiple challenges may more adequately approximate natural exposure.
- Trial name
- NCT01286129
- Testing
- Nasal allergen challenge
- Where
- Canada
- Volunteers
- 45 people
- Sponsor
- Laval University
Type 1 Diabetes, Asthma
EmoTIChealth: Promoting Adolescent Health Through a Serious Game.
The intervention program targets adolescents between 12 and 16 years of age. The intervention program is designed for adolescents during a critical developmental stage marked by significant life transitions, where building strong…
- Conditions
- Type 1 Diabetes, Asthma, Allergic Rhinitis, Food Allergy
- Trial name
- NCT07212530
- Testing
- EmoTIChealth
- Where
- Spain
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- University of Valencia
Allergic Rhinitis
Repeat Dose Nasal Allergen Challenge
What happens in the nose during an allergic reaction? Are there changes that a new drug could treat? What is the best way to test new drugs?The response of the nose to being exposed to cat allergen in someone who is allergic to…
- Trial name
- NCT01110837
- Testing
- Allergen
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- McMaster University
Allergic Rhinitis
"Efficacy and Safety of Phlai Capsule Compared to Placebo as the Treatment in Allergic Rhinitis Patients"
Background: Zingiber cassumunar Roxb., frequently known as Phlai in Thai, has been safely used as an antihistaminic and anti-inflammatory drug in Thai traditional medicine.
- Trial name
- NCT04182919
- Testing
- Phlai
- Where
- Thailand
- Volunteers
- 267 people, healthy volunteers welcome
- Sponsor
- Chulalongkorn University
Allergic Rhinitis
Skin Prick Tests With AllerT in Subjects Allergic to Birch Pollen
Assessment of skin reactivity by skin prick tests to synthetic peptides derived from the major birch allergen bet v 1, in subjects allergic to birch pollen.
- Trial name
- NCT01719133
- Testing
- Histamine, AllerT1, AllerT2
- Where
- Switzerland
- Volunteers
- 20 people
- Sponsor
- Anergis
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