Clinical trials: Allergic Rhinitis (Disorder)
Rhinitis, Allergic, Seasonal
Compare the Efficacy of Levocetirizine and Montelukast to Placebo in Reducing Seasonal Allergic Rhinitis (SAR) Symptoms in Ragweed Sensitive Subjects
To compare the clinical efficacy of levocetirizine 5 mg and montelukast 10 mg on symptoms of seasonal allergic rhinitis occurring in subjects exposed to ragweed pollen in an environmental exposure unit.
- Trial name
- NCT00295022
- Testing
- Montelukast, Levocetirizine
- Where
- Canada
- Volunteers
- 418 people
- Sponsor
- UCB S.A. - Pharma Sector
Allergic Rhinitis, Perennial Allergic Rhinitis
Clinical Trial to Evaluate the Safety and Efficacy of AGR Tablet as a Treatment of Perennial Allergic Rhinitis in Korean
The purpose of this study is to evaluate treatment of perennial allergic rhinitis in Korean patients with AGR tablet.
- Conditions
- Allergic Rhinitis, Perennial Allergic Rhinitis, Non-seasonal Allergic Rhinitis
- Trial name
- NCT01982916
- Testing
- AGR tablet, Active Comparator
- Where
- 9 sites in South Korea
- Volunteers
- 324 people
- Sponsor
- Ahn-Gook Pharmaceuticals Co.,Ltd
Rhinitis, Allergic, Perennial
Single Dosing Clinical Trial of HL151
The purpose of this study is to assess the pharmacokinetic characteristics of bepotastine after single oral administration of TALION tab, a IR formulation of bepotastine as reference drug and HL151, a SR formulation of…
- Trial name
- NCT02682745
- Testing
- HL151, TALION tab.
- Where
- South Korea
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Hanlim Pharm. Co., Ltd.
Asthma, Allergic Rhinitis
Clinical Response to Rhinovirus Challenge
Rhinovirus (RV) infections represent the most common cause of asthma exacerbations in children and adolescents. The investigators hypothesize that the immune responses generated in the nose of allergic rhinitics and asthmatics…
- Trial name
- NCT02910401
- Testing
- Rhinovirus (GMP RV16 HRV-16)
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- University of Virginia
COVID-19, Allergic Rhinitis
the Relationship Between Allergic Rhinitis and the Risk of Symptom in Patients With Mild COVID-19
At present, most studies mainly focussed on severe patients, and there was no comparison of symptom differences between AR patients and healthy people with mild infection to evaluate the symptoms of AR patients during infection…
- Trial name
- NCT05753241
- Testing
- no intervention
- Where
- China
- Volunteers
- 1,100 people, healthy volunteers welcome
- Sponsor
- qinxiu zhang
Asthma, Allergic Rhinitis
Nasal Allergen Challenge in Rhinitic Subjects
Background: Nasal allergen challenge (NAC) is useful to study the pathophysiology of rhinitis, and multiple challenges may more adequately approximate natural exposure.
- Trial name
- NCT01286129
- Testing
- Nasal allergen challenge
- Where
- Canada
- Volunteers
- 45 people
- Sponsor
- Laval University
Rhinitis, Allergic, Perennial
Investigation of the Efficacy and Safety of Concomitant Administration of Ciclesonide Nasal Spray and Azelastine Nasal Spray in Patients (18 Years or Older) With Perennial Allergic Rhinitis (PAR) Not Adequately Controlled on an Intranasal Corticosteroid or Antihistamine Monotherapy (BY9010/M1-490)
The primary objective of this study is to evaluate the efficacy of the concomitant administration of ciclesonide nasal spray and azelastine nasal spray versus ciclesonide nasal spray alone in patients (18 years or older) with…
- Trial name
- NCT00806754
- Testing
- Ciclesonide nasal spray + Azelastine
- Where
- 35 sites in United States
- Volunteers
- 340 people
- Sponsor
- AstraZeneca
Rhinitis, Allergic, Perennial
Repeated Dosing Clinical Trial of HL151
The purpose of this study is to assess the pharmacokinetic characteristics of bepotastine after multiple oral administration of TALION tab., a IR formulation of bepotastine as reference drug and HL151, a SR formulation of…
- Trial name
- NCT02686294
- Testing
- HL151, TALION tab.
- Where
- South Korea
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Hanlim Pharm. Co., Ltd.
Perennial Allergic Rhinitis
NasoNeb Delivery of an Intranasal Steroid
The purpose of this study is to see if a nasal steroid drug delivered to the nose with the NasoNeb™ inhaler improves the symptoms of people with perennial allergic rhinitis (year round allergy symptoms).
- Trial name
- NCT01270256
- Testing
- Budesonide
- Where
- United States
- Volunteers
- 41 people
- Sponsor
- University of Chicago
Eczema, Asthma
Influence of Probiotics on Prevention of Atopy, Atopic Disease and Immunological Responses
This will be a double-blind, randomized placebo-controlled study. 253 children were recruited and randomly assigned into one of 2 groups to receive either normal infant formula or formula with Bifidobacterium longum and…
- Conditions
- Eczema, Asthma, Allergic Rhinitis
- Trial name
- NCT00318695
- Testing
- Probiotics
- Where
- Singapore
- Volunteers
- 253 people, healthy volunteers welcome
- Sponsor
- National University Hospital, Singapore
Seasonal Allergic Rhinitis
Phase II/III Seamless Clinical Study of MG-K10 Humanized Monoclonal Antibody Injection in Treatment of Seasonal Allergic Rhinitis
A multicenter, randomized, double-blind, placebo-controlled Phase II/III seamless clinical study evaluating the efficacy, safety, pharmacokinetic (PK) profile, pharmacodynamic (PD) profile, and immunogenicity of MG-K10 humanized…
- Trial name
- NCT06846385
- Testing
- MG-K10 Humanized Monoclonal Antibody Injection
- Where
- China
- Volunteers
- 160 people
- Sponsor
- Shanghai Mabgeek Biotech.Co.Ltd
Asthma
The Status of Asthma in the Korean Military Personnel
The aim of this study is to evaluate the status of allergic diseases in the Korean military personnel.
- Trial name
- NCT00982085
- Where
- South Korea
- Volunteers
- 4,000 people, healthy volunteers welcome
- Sponsor
- Armed Forces Capital Hospital, Republic of Korea
Allergy Dermatophagoides Pteronyssinus, Allergic Rhinitis
Biological Standardization of Dermatophagoides Pteronyssinus Allergen Extract
The objective of this study is to determine the biologic activity of a Dermatophagoides pteronyssinus allergen extract in histamine equivalent prick (HEP) units, in order to be used as in-house reference preparation (IHRP).
- Conditions
- Allergy Dermatophagoides Pteronyssinus, Allergic Rhinitis, Allergic Asthma
- Trial name
- NCT01821716
- Testing
- Prick test Dermatophagoides pteronyssinus allergen extract
- Where
- 2 sites in Spain
- Volunteers
- 42 people
- Sponsor
- Laboratorios Leti, S.L.
Rhinitis, Allergic, Perennial
Comparator Study Evaluating Patient Preference Of FFNS vs. FPNS
The purpose of this replicate study to FFU105927 is to provide data on subject preference of FFNS as compared with FPNS.
- Trial name
- NCT00539006
- Testing
- FPNS, FFNS
- Where
- 24 sites in United States
- Volunteers
- 377 people
- Sponsor
- GlaxoSmithKline
Seasonal Allergic Rhinitis
Reduction of IgE Antibody in Human Allergic Subjects
The purpose of this study is to determine whether a neuropeptide, substance P, when injected along with an allergen, such as ragweed, can reduce allergic reactivity.
- Trial name
- NCT01280149
- Testing
- substance P, substance P injections
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Northwestern University
Rhinitis, Allergic, Perennial
Investigation of Potential Additive Inhibitory Effects on HPA-Axis of Ciclesonide Nasal Spray When Administered Concomitantly With Orally Inhaled Beclomethasone Dipropionate (HFA-BDP) in Patients With Perennial Allergic Rhinitis (PAR) (BY9010/M1-408)
The primary objective of this study is to demonstrate that there are no clinically relevant additive inhibitory effects on the HPA-axis when ciclesonide nasal spray is concomitantly administered with orally inhaled HFA-BDP.
- Trial name
- NCT00659048
- Testing
- Ciclesonide
- Where
- United States
- Volunteers
- 106 people
- Sponsor
- AstraZeneca
Hypersensitivity, Psychologic Factors in Physical Conditions Classified Elsewhere
Interaction Effect of Asthma and Aeroallergen Category on the Psychological Status in Allergic Rhinitis Patients
Allergic rhinitis (AR) and asthma are considered as "one airway, one disease". Although there is increasing evidence for an association between allergy and depression, it remains unknown if the relationship between AR and asthma…
- Conditions
- Hypersensitivity, Psychologic Factors in Physical Conditions Classified Elsewhere, Respiratory Tract Diseases, Allergic Rhinitis
- Trial name
- NCT01295255
- Volunteers
- 524 people
- Sponsor
- Beijing Tongren Hospital
Allergic Rhinitis, Allergic Reaction
Efficacy and Safety of Birch Pollen Immunotherapy in Local Allergic Rhinitis
Local allergic rhinitis (LAR) is relatively new disease. The question of effect of allergen specific immunotherapy on LAR is open.
- Trial name
- LARbirch (NCT03157505)
- Testing
- Purethal Birch immunotherapy
- Volunteers
- 78 people
- Sponsor
- Medical University of Silesia
Nasal Obstruction Present Finding
Effectiveness of Oxymetazoline Added on Nasal Steroid in Rhinitis With Persistent Nasal Obstruction
Background Allergic rhinitis is a common health problem with a worldwide prevalence is 10-25%, and poses significant impact on the quality of life of the patients.
- Trial name
- NCT01847131
- Testing
- oxymetazoline
- Where
- Thailand
- Volunteers
- 50 people
- Sponsor
- Mahidol University
Seasonal Allergic Rhinitis
Mometasone Furoate on Sleep Disturbances in Subjects With Seasonal Allergic Rhinitis (Study P04608) (COMPLETED)
This study will hope to show that by relieving the participant's nasal symptoms of seasonal allergies using mometasone furoate nasal spray, the participant will obtain a better quality of night-time sleep, which in turn, causes…
- Trial name
- NCT00358527
- Testing
- Mometasone Furoate Nasal Spray (MFNS)
- Volunteers
- 401 people
- Sponsor
- Organon and Co
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