Clinical trials: Allergic Rhinitis (Disorder)
Allergic Rhinitis
Effect of Nasaleze on Nasal Challenge With Allergen
The objectives of this protocol are: 1. to confirm the inhibitory effect of Nasaleze on the immediate response to nasal challenge with antigen, and 2.
- Trial name
- NCT01723397
- Testing
- Nasaleze Spray, Allergen
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- University of Chicago
Rhinitis, Allergic, Perennial
Study Of Perennial Allergic Rhinitis In Pediatrics
To verify of cetirizine dry syrup to ketotifen dry syrup in the change of total nasal symptom score (TNSS) over the total treatment period from the score of the baseline assessment period
- Trial name
- NCT00253058
- Testing
- Cetirizine Dry Syrup
- Volunteers
- 286 people
- Sponsor
- GlaxoSmithKline
Seasonal Allergic Rhinitis
The Efficacy of Preseasonal Omalizumab Treatment
Allergic rhinitis (AR) is induced by an immunoglobulin E (IgE)-mediated reaction in the allergen-sensitized subjects, affecting 10% to 40% of the world population.
- Trial name
- NCT04489121
- Testing
- Omalizumab
- Where
- China
- Volunteers
- 31 people
- Sponsor
- Beijing Tongren Hospital
Cough, Cough Variant Asthma
MCT and Capsaicin Provocation Challenge in Diagnosis of Chronic Cough
The aim of the study is to assess the prevalence of bronchial hyperresponsiveness (BHR) in non-smoking adults with chronic cough and the prevalence of BHR in patients with upper airway cough syndrome (UACS) and gastroesophageal…
- Conditions
- Cough, Cough Variant Asthma, Upper-Airway Cough Syndrome, GERD
- Trial name
- NCT03363698
- Testing
- Cough variant asthma treatment
- Where
- Poland
- Volunteers
- 55 people
- Sponsor
- Medical University of Warsaw
Allergic Rhinitis, Allergic Rhinoconjunctivitis
PURETHAL Birch RUSH Study
This study investigates the safety of two up-dosing regimen. The safety of PURETHAL Birch will be evaluated in a rush regimen (maximum dose reached in 3 injections during 3 weeks) compared to the conventional regimen (maximum…
- Trial name
- NCT01918956
- Testing
- PURETHAL Birch, 20.000 AUM/ml
- Where
- 8 sites in Poland
- Volunteers
- 120 people
- Sponsor
- HAL Allergy
Allergic Rhinitis, Asthma
Development of Human Nasal Challenge Models With Microbial Constituents and Grass Pollen
The investigators propose the development of a range of nasal spray challenge models to study the way the nose can respond to different types of nasal challenge that elicit different forms of inflammation.
- Conditions
- Allergic Rhinitis, Asthma, Latent Tuberculosis
- Trial name
- NCT02090374
- Testing
- Poly ICLC, Poly I:C, R848
- Where
- United Kingdom
- Volunteers
- 93 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Perennial Allergic Rhinitis
Levocetirizine Effect on Nasal Nitric Oxide and Nasal Eosinophils in Subjects With Perennial Allergic Rhinitis
The purpose of this study is to noninvasively measure the anti-inflammatory effect of levocetirizine after two weeks of treatment in allergic rhinitis subjects.
- Trial name
- NCT00894231
- Testing
- levocetirizine (Xyzal)
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- AAADRS Clinical Research Center
Non-allergic Rhinitis
Elaboration of Patient-friendly Treatment Strategy With Capsaicin Nasal Spray in Patients With Idiopathic Rhinitis
Chronic rhinitis is affecting more than 200 million people worldwide. Its prevalence is estimated to be as high as 30% of the Western population.
- Trial name
- NCT02288156
- Testing
- Capsaicin
- Where
- Belgium
- Volunteers
- 80 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Allergic Conjunctivitis, Seasonal Allergies
A Safety and Activity Study of NS2 in Subjects With Allergic Conjunctivitis
This is a randomized, parallel, single center, double masked, vehicle controlled study. The purpose of this study is to determine the activity and safety of NS2 in patients with grass, tree or ragweed-pollen induced seasonal…
- Trial name
- NCT02578914
- Testing
- NS2 Ophthalmic Drops (0.5%), NS2 Ophthalmic Drops Vehicle (0.0%)
- Where
- Canada
- Volunteers
- 100 people
- Sponsor
- Aldeyra Therapeutics, Inc.
Asthma, Allergy
Treatment of Ragweed-Allergic Asthma With an Immunostimulatory Drug
This study will test the effectiveness of an investigational treatment for patients with ragweed-induced asthma, sometimes called fall seasonal asthma. The treatment being tested is a series of anti-ragweed shots.
- Conditions
- Asthma, Allergy, Allergic Rhinitis, Rhinitis, Allergic, Seasonal
- Trial name
- NCT00318747
- Testing
- Amb a 1-immunostimulatory oligodeoxyribonucleotide conjugate (AIC)
- Where
- 4 sites in United States
- Volunteers
- 140 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Allergic Rhinitis, Rhinitis, Allergic, Seasonal
A Phase II Study Evaluating Intranasal GSK256066 and Azelastine Hydrochloride in Subjects With Seasonal Allergic Rhinitis
This study is an 8 day, randomised, double blind, 2-way crossover trial of repeat doses of intranasal GSK256066 and azelastine hydrochloride in the Vienna Challenge Chamber in subjects with seasonal allergic rhinitis (SAR).
- Trial name
- NCT00612118
- Testing
- GSK256066, azelastine hydrochloride
- Where
- Austria
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Seasonal Allergic Rhinitis
Effects of Imatinib in Subjects With Seasonal Allergic Rhinitis and Who Are Sensitive to Timothy Grass Pollen
This study will assess the effects of Imatinib on allergic inflammation following repeated nasal allergen challenge in subjects with seasonal allergic rhinitis sensitive to Timothy grass pollen.
- Trial name
- NCT00426179
- Testing
- Imatinib
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- Novartis
Allergic Rhinitis
Acute Effect of High Intensity Interval Exercise in Patients With Allergic Rhinitis
The purpose of this study was to determine the acute effect of high intensity interval exercise on respiratory function and rhinitis symptoms in allergic rhinitis patients.
- Trial name
- NCT05779046
- Testing
- HIT 1:1, HIT 1:2
- Where
- Thailand
- Volunteers
- 12 people
- Sponsor
- Chulalongkorn University
Perennial Allergic Rhinitis, PAR
A Safety and Efficacy Study of Ciclesonide Nasal Aerosol in Subjects 6-11 Years With Perennial Allergic Rhinitis (PAR).
This is a 12-week, multicenter, randomized, double-blind, placebo-controlled, parallel-group, efficacy and safety study of ciclesonide nasal aerosol administered once daily to male and premenarchal female subjects 6 to 11 years…
- Trial name
- NCT01451541
- Testing
- Ciclesonide nasal aerosol 37 mcg, ciclesonide nasal aerosol 74 mcg
- Where
- 60 sites in United States
- Volunteers
- 848 people
- Sponsor
- Sumitomo Pharma America, Inc.
Allergic Rhinitis
Effect of Qi-tonifying Chinese Herbal Products for Treatment of Allergic Rhinitis
Allergic rhinitis is a common but complicated immunologic disorder disease and multiple western medicine has been used for symptom control.
- Trial name
- NCT01631032
- Testing
- Qi-tonifying Chinese herbal products
- Where
- Taiwan
- Volunteers
- 112 people
- Sponsor
- Chang Gung Memorial Hospital
Asthma, Allergic Rhinitis
A Study to Compare Effectiveness of Montelukast Sodium With Comparator in Mild to Moderate Persistent Asthmatics (0476-329)
Subjects have 8-week with montelukast sodium or comparator drug administration period, 2-week wash-out period and 8-week comparator drug or the drug administration period (with cross-over design) for assessment of the drug…
- Trial name
- NCT00157937
- Testing
- MK0476; montelukast sodium/Duration of Treatment: 16 weeks, Comparator: theophylline ER/Duration of Treatment: 16 weeks
- Volunteers
- 31 people
- Sponsor
- Organon and Co
Seasonal Allergic Rhinitis
Effect of Intranasal Corticosteroids on Systemic Allergen Specific IgE
Evaluation of the effect of fluticasone propionate vs placebo applied as nasal spray on the increase of allergen-specific serum IgE levels following nasal exposure to recombinant allergens.
- Trial name
- NCT00755066
- Testing
- Fluticasone propionate
- Where
- Austria
- Volunteers
- 48 people
- Sponsor
- Medical University of Vienna
Seasonal Allergic Rhinitis
Efficacy, Safety and Underlying Mechanisms of Sphenopalatine Ganglion Acupuncture for Seasonal Allergic Rhinitis
In recent years, a number of randomized controlled trials have confirmed the efficacy and safety of acupuncture in the treatment of allergic rhinitis (AR).
- Trial name
- NCT04052945
- Testing
- SPA acupuncture
- Where
- China
- Volunteers
- 70 people
- Sponsor
- Beijing Tongren Hospital
Allergic Rhinitis
Study on the Effect and Mechanism of Lupatadine Fumarate in the Treatment of Allergic Rhinitis
In China, the prevalence of allergic rhinitis reaches 17.6% and is increasing year by year, seriously affecting the quality of life of patients. Some patients still cannot be effectively treated.
- Trial name
- NCT06709092
- Testing
- lupatadine fumarate (Luso®, Yangzijiang Pharmaceuticals)
- Where
- 2 sites in China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Cheng Lei
Rhinitis, Allergic, Perennial
Efficacy and Safety of Cetirizine Tablets Versus Ketotifen Dry Syrup in Children With Perennial Allergic Rhinitis
Ketotifen is an established antihistamine drug, widely used in pediatric clinical practice in Japan. The objective of the study was to compare the efficacy and safety of cetirizine hydrochloride versus ketotifen dry syrup on…
- Trial name
- NCT00639587
- Testing
- Ketotifen, Cetirizine
- Volunteers
- 149 people
- Sponsor
- UCB Pharma
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