Clinical trials: Allergy in Children
Peanut Hypersensitivity, Food Hypersensitivity
Peanut Epicutaneous Phase II Immunotherapy Clinical Trial
Food allergy occurs when the immune system reacts against foods. The immune system is the part of the body that protects us from illness and germs, but it can also cause allergies.
- Conditions
- Peanut Hypersensitivity, Food Hypersensitivity, Hypersensitivity, Hypersensitivity, Immediate
- Trial name
- NCT01904604
- Testing
- Low-dose DBV712 Viaskin® Patch, High-dose DBV712 Viaskin® Patch
- Where
- 5 sites in United States
- Volunteers
- 75 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Asthma
Effects of Ciclesonide MDI 50mg/Day and 200mg/Day (Ex-Valve) Once-Daily on Growth in Children With Mild Persistent Asthma
The primary objective is to determine if CIC 50 mg/day or 200 mg/day (ex-valve) administered once daily in the morning is non-inferior to placebo with respect to growth velocity in children with mild persistent asthma following a…
- Trial name
- NCT00270348
- Testing
- ciclesonide
- Volunteers
- 450 people
- Sponsor
- Sanofi
Asthma
Efficacy of Symbicort pMDI Administered Once Daily in Children and Adolescents During 12 Weeks - SPROUT
The purpose of this study is to compare Symbicort with budesonide alone for the treatment of asthma in children aged 6 to 15 years
- Trial name
- NCT00646321
- Testing
- budesonide/formoterol (Symbicort), budesonide
- Volunteers
- 540 people
- Sponsor
- AstraZeneca
Atopic Dermatitis
Topical L. Reuteri in Children With Atopic Dermatitis
This study evaluates the safety and efficacy of the probiotic L. reuteri vs control product as an adjuvant for improving the skin appearance of children with mild or moderate atopic dermatitis.
- Trial name
- ADreuteri (NCT04265716)
- Testing
- Topical L. reeuteri
- Where
- Mexico
- Volunteers
- 102 people
- Sponsor
- Innovacion y Desarrollo de Estrategias en Salud
Asthma
Evaluation of Efficacy and Safety for Single Dose of E004 in Children With Asthma
This is a multi-center, randomized, double-blinded, placebo-controlled, crossover, single dose study in 24 pediatric patients (4-11 years old) with asthma.
- Trial name
- NCT01737905
- Testing
- Epinephrine HFA-MDI (E004)
- Where
- 6 sites in United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Amphastar Pharmaceuticals, Inc.
Allergic Rhinitis
Comparison of Desloratadine Associated With Prednisolone Oral Solution Versus Dexchlorpheniramine Associated With Betamethasone for Persistent Allergic Rhinitis Treatment
The purpose of this study is to evaluate the non-inferiority clinical efficacy of two different drug associations in the treatment of Moderate - Severe Persistent Allergic Rhinitis.
- Trial name
- NCT01529229
- Testing
- Dexchlorpheniramine + Betamethasone, Desloratadine + Prednisolone
- Volunteers
- 210 people
- Sponsor
- EMS
Asthma
Open-label, Safety and Efficacy Study of Pulmicort® Turbuhaler® in Japanese Children With Bronchial Asthma
To investigate the effect and safety of budesonide Turbuhaler® 100 μg/dose and 200 μg/dose twice daily for 6 weeks in Japanese children with bronchial asthma aged 5 years to 15 years old in need for inhaled glucocorticosteroid…
- Trial name
- NCT00504062
- Testing
- budesonide, fluticasone
- Where
- Japan
- Volunteers
- 240 people
- Sponsor
- AstraZeneca
Avoidant and Restrictive Food Intake Disorders
Avoidant and Restrictive Food Intake Disorders (ARFID) in Adolescence: Early Oral Development, Psychopathological Profile and Sensory Integration
The purpose of this study is to assess if adolescents affected with Avoidant and Restrictive Food Intake Disorders (ARFID) had more frequent precocious pediatric feeding disorders before 4 years old compared to healthy…
- Trial name
- ARFIDOS (NCT06665802)
- Testing
- Questionnaire
- Where
- 3 sites in France
- Volunteers
- 60 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Asthma
Teaching Children With Asthma and Who Live in a Rural Setting How to Self-Manage Their Asthma
To determine if teaching rural children with asthma and their parents about appropriate medication use, asthma triggers unique to a rural setting and increasing access to medical care will result in a decrease in emergency…
- Trial name
- NCT00218803
- Testing
- Nurse asthma education intervention, Control Group
- Where
- United States
- Volunteers
- 220 people
- Sponsor
- National Institute of Nursing Research (NINR)
Asthma
Asthma Severity in Children and Environmental Agents
This study measures residential exposures (indoor allergens, mold, nitrogen dioxide, nicotine) and relates exposure levels to daily symptoms (wheeze, persistent cough, chest tightness, shortness of breath) and medication use, in…
- Trial name
- NCT00042705
- Where
- United States
- Sponsor
- National Institute of Environmental Health Sciences (NIEHS)
Parent-Child Relations, Depressive Symptoms
Video Feedback to Improve Parental Sensitivity in Mother-infant Dyads With Depressive Symptoms
Title: "Internet mentalization-based video feedback intervention to improve parental sensitivity in mother-infant dyads with maternal depressive symptoms: randomized controlled feasibility trial".
- Trial name
- NCT04748731
- Testing
- Internet mentalization-based video feedback intervention to improve parental sensitivity in mother-infant dyads with maternal depressive symptoms, Psycho-Educational Intervention
- Where
- Chile
- Volunteers
- 86 people
- Sponsor
- Pontificia Universidad Catolica de Chile
Sensitive Dentin, Hypomineralization Molar Incisor
BIOSILITACE AS A DESENSITIZING AGENTIN HMI
Molar-Incisor Hypomineralization (MIH) is a qualitative enamel defect caused by systemic hypomineralization that affects one to four first permanent molars, and may or may not involve incisors.
- Conditions
- Sensitive Dentin, Hypomineralization Molar Incisor, Pain
- Trial name
- BDAHMI (NCT07080645)
- Testing
- Pain Relieving, topical application
- Where
- 2 sites in Brazil
- Volunteers
- 42 people
- Sponsor
- University of Sao Paulo
Atopic Dermatitis
Immune Response to Varicella Vaccination in Children With Atopic Dermatitis
Atopic dermatitis (AD) causes people to be susceptible to skin infection and inflammations. The purpose of this study is to determine the immune response to chicken pox vaccine in children with or without AD who received the…
- Trial name
- NCT00406081
- Where
- 2 sites in United States
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Asthma
Study of Methacholine Chloride Inhalation Challenge in Children With Bronchial Asthma
The Purpose of this study is to evaluate the safety and efficacy of SK-1211 inhalation challenge in children with bronchial asthma.
- Trial name
- NCT02097537
- Testing
- Methacholine Chloride (SK-1211)
- Where
- Japan
- Volunteers
- 10 people
- Sponsor
- Santen Pharmaceutical Co., Ltd.
Sickle Cell Disease
Sickle Cell Pro-Inflammatory Response to Interval Training Study
Recommendations for exercise prescription currently do not exist for individuals with sickle cell anemia (SCA) despite the known impact that SCA-related complications has on physical functioning and fitness.
- Trial name
- SPRINTS (NCT03653676)
- Testing
- Exercise Test (CIIT)
- Where
- 3 sites in United States
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Ann & Robert H Lurie Children's Hospital of Chicago
Allergy Milk
Tolerability of Hypoallergenic Formula in Children With Cow's Milk Allergy
Cow's milk protein allergy is defined as an immunological reaction to one or more milk proteins. A variety of symptoms can be suggestive for cow's milk protein allergy .
- Trial name
- SINEALLII (NCT03909113)
- Testing
- amino acid based formula
- Where
- Italy
- Volunteers
- 29 people
- Sponsor
- Federico II University
Asthma in Children
Improving Asthma Referrals Following Emergency Department Evaluation
Asthma is the most common chronic condition among children and many children seek emergency department (ED) care. A key aspect of ED asthma management at the time of discharge is appropriate outpatient referral.
- Trial name
- NCT05072808
- Testing
- View PACCI-ED and referral recommendations
- Where
- United States
- Volunteers
- 76 people
- Sponsor
- Wayne State University
Asthma
Positive Expiratory Pressure for the Treatment of Acute Asthma in Children
Asthma is a leading cause of emergency department (ED) visits for children. A novel way of treating asthma is the use of positive expiratory pressure (PEP).
- Trial name
- NCT02494076
- Testing
- EzPAP, Standard Care
- Where
- United States
- Volunteers
- 52 people
- Sponsor
- University of Colorado, Denver
Bronchial Asthma
Evaluation of the Delay in Asthma Diagnosis in Children From the Lodz Region
The aim of the research is to assess the duration of a delay in asthma diagnosis in children after the Program for Prevention of Allergic Diseases. Risk factors for delayed diagnosis of asthma in children will also be assessed.
- Trial name
- NCT01084317
- Testing
- medical documentation and telephone interview
- Where
- Poland
- Volunteers
- 907 people
- Sponsor
- Medical University of Lodz
Asthma in Children, Pollution; Exposure
Evidence Driven Indoor Air Quality Improvement
The aim is to identify the underlying disease mechanisms driving specific asthma phenotypes as well as certain disease outcomes and their relation to impaired indoor air quality.
- Trial name
- NCT05992389
- Where
- Croatia
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Srebrnjak