Clinical trials: Allodynia
Healthy, Hyperalgesia
Influence of Genetics in Pain Sensitivity
The purpose of this study is to learn more about the role of genetics in pain sensitivity. Pain perception varies widely among individuals, and information gained from this trial may lead to better methods of preventing and…
- Conditions
- Healthy, Hyperalgesia, Pain
- Trial name
- NCT00001956
- Testing
- Blood draw, Oral surgery, Tissue biopsy
- Where
- United States
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- National Institute of Dental and Craniofacial Research (NIDCR)
Hyperalgesia, Pain
Effect of High Dose Naloxone on Secondary Hyperalgesia
Recent studies have focused on the role of endogenous opioids on central sensitization. Central sensitization is known to be impaired or altered in chronic pain conditions, as fibromyalgia or chronic tension headache.
- Conditions
- Hyperalgesia, Pain, Naloxone, Opioid Antagonist
- Trial name
- NCT01935206
- Testing
- Naloxone (2 mg/kg)
- Where
- 2 sites in Denmark
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Diabetic Peripheral Neuropathy, Chronic Pain
Safety and Efficacy of AEG33773 Versus Placebo in Patients With Painful Diabetic Peripheral Neuropathy
Two Phase 1 studies have been conducted with AEG33773 and available safety and tolerability data from these studies support further clinical development of AEG33773.
- Trial name
- NCT00891683
- Testing
- AEG33773 oral dosing
- Where
- 20 sites in United States, Bulgaria and 2 more
- Volunteers
- 128 people
- Sponsor
- Aegera Therapeutics