Clinical trials: Alopecia Areata
Alopecia Areata
Study to Evaluate the Safety and Efficacy of Jaktinib in Adults With Alopecia Areata
This is a multi-center Phase 3 study to evaluate the safety and effectiveness of an investigational study drug (called Jaktinib) in adults (≥18 years and <65 years) who have 50% or greater scalp hair loss.
- Trial name
- AA (NCT05051761)
- Testing
- Jaktinib
- Where
- 2 sites in China
- Volunteers
- 425 people
- Sponsor
- Suzhou Zelgen Biopharmaceuticals Co.,Ltd
Alopecia Areata
Investigate the Efficacy and Safety of Farudodstat Compared With Its Placebo in Adult Alopecia Areata Participants
The main purpose of this study is to measure the efficacy of farudodstat compared to placebo at Week 12 from the treatment start, in adult participants with Alopecia Areata (AA) with 30% or greater scalp hair loss.
- Trial name
- FAST-AA (NCT05865041)
- Testing
- Farudodstat
- Where
- 19 sites in United States
- Volunteers
- 60 people
- Sponsor
- ASLAN Pharmaceuticals
Alopecia Areata
Clinical Trial on the Efficacy of Intralesional Triamcinolone Versus Candida Albicans Antigen in Treating Alopecia Areata
The efficacy of two intralesional treatment modalities for alopecia areata will be determined. Thirty patients over the age of 6 with the diagnosis of alopecia areata on the scalp, with an extension of less than 50%, will be…
- Trial name
- NCT06564805
- Testing
- Candida Albicans Antigen Injection
- Where
- Mexico
- Volunteers
- 30 people
- Sponsor
- Universidad Autonoma de Nuevo Leon
Alopecia Areata
1565nm Non-ablative Fractional Laser Treat Alopecia Areata
The goal of this clinical trial is to evaluate and explore the mechanism of 1565-nm non-ablative fractional laser in the treatment of alopecia areata.
- Trial name
- NCT05744505
- Testing
- 1565nm Non-ablative Fractional Laser
- Where
- China
- Volunteers
- 10 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Androgenetic Alopecia, Androgenetic Alopecia (AGA)
The Effect of Nanofat Injection on Androgenetic Alopecia
Androgenetic alopecia is a condition that bothers a lot of people. The disadvantage of the FDA approved topical minoxidil is that the patient needs to be compliant every day for extended periods of time.
- Trial name
- NCT07518342
- Testing
- Minoxidil 5 %, PRP injection, Nanofat injection
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Assiut University
Alopecia
The Parallel Study to Evaluate the Pharmacokinetics, Pharmacodynamics, and Safety of CKD-843 A
A study to evaluate the pharmacokinetics, pharmacodynamics, and safety of CKD-843 A in male subjects.
- Trial name
- NCT05587699
- Testing
- CKD-843 A 45mg(Multiple dose), CKD-843 A 45mg, CKD-843 A 55mg(Multiple dose)
- Where
- South Korea
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Chong Kun Dang Pharmaceutical
Androgenetic Alopecia
Androgenetic Alopecia and the JAK-STAT Pathway
It is a well known fact that the JAK-STAT pathway plays a pivotal role in the pathogenesis of alopecia areata. Both phosphorylated STAT 1 and 3 have been found to be upregulated in the disease.
- Trial name
- NCT03694067
- Testing
- Punch skin biopsy
- Where
- Egypt
- Volunteers
- 25 people
- Sponsor
- Cairo University
Rheumatoid Arthritis, Ankylosing Spondylitis
PatientSpot Formerly Known as ArthritisPower
Patient Power is a patient research network and database (registry) to collect prospective information about demographics, self-reported diagnoses and medications, and willingness to participate in research from participants with…
- Conditions
- Rheumatoid Arthritis, Ankylosing Spondylitis, Fibromyalgia, Gout
- Trial name
- NCT03840928
- Where
- United States
- Volunteers
- 40,000 people, healthy volunteers welcome
- Sponsor
- Global Healthy Living Foundation
Androgenetic Alopecia
Use of Botulinum Toxin in the Treatment of Androgenic Alopecia
The purpose of this study is to evaluate the effect of using a purified botulinum toxin (Xeomin®, Merz, USA), the same injectable used to improve face wrinkles, to treat a specific type of hair loss seen in men and women not…
- Trial name
- NCT05456087
- Testing
- incobotulinumtoxin A
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Zel Skin and Laser Specialists
Alopecia
Treatment of Alopecia Using Follicular Stem Cells
Treatment of alopecia using the injections of cultured stem cells from human hair follicles,(which contain epithelial and mesenchymal cells stem cell)
- Trial name
- NCT05210452
- Testing
- Follicular stem cells, Standard treatment according to the clinical protocols
- Volunteers
- 30 people
- Sponsor
- Institute of Biophysics and Cell Engineering of National Academy of Sciences of Belarus
Androgenetic Alopecia, Cicatricial Alopecia
Evidence-Based Integrated Protocol to Maximize Hair Follicle Survival in Follicular Unit Extraction (FUE)
Follicular unit extraction (FUE) is a widely used surgical technique for hair restoration, yet hair follicle survival rates vary depending on surgical instrumentation, graft handling, and perioperative care.
- Trial name
- NCT07850011
- Testing
- Integrated Evidence-Based FUE Protocol, Standard FUE Practice
- Volunteers
- 30 people
- Sponsor
- Assiut University
Hair Loss
Evaluation of the Performance of a Nutricosmetic on Hair & Scalp in Women and Men After 3 and 6 Months
In order to validate the product performance, L'Oréal R\&I decided to conduct a new clinical study. The final product is intended to be performant in men and women.
- Trial name
- NCT07556016
- Testing
- Active nutricosmetic
- Where
- 4 sites in France
- Volunteers
- 239 people, healthy volunteers welcome
- Sponsor
- L'Oreal
Chemotherapy-induced Alopecia
Prevention of Alopecia in Patients With Localised Breast Cancer
The prevention of chemotherapy-induced alopecia (CIA) is still imperfectly managed in France. Strengthening the evidence base on the benefits of strategies to prevent CIA, based on robust methodologies, remains a prerequisite for…
- Trial name
- ICELAND (NCT06011525)
- Testing
- standard cold cap, scalp-cooling technique
- Where
- 3 sites in France
- Volunteers
- 196 people
- Sponsor
- Centre Francois Baclesse
Neoplasm Malignant, Breast Cancer
Shorter Scalp Cooling Time in Paclitaxel
Chemotherapy-induced alopecia (CIA) is one of the most distressing side effects for patients. Scalp cooling can prevent or minimise CIA in approximately half of all patients, depending on many factors, e.g.
- Conditions
- Neoplasm Malignant, Breast Cancer, Ovarian Cancer
- Trial name
- COP (NCT03266185)
- Testing
- Shorter PICT
- Where
- Netherlands
- Volunteers
- 91 people
- Sponsor
- Leiden University Medical Center
Advanced or Metastatic Solid Tumour, Antibody-Drug Conjugate
SCALp Cooling for pReventing aLopecia With nEw anTibody-drug Conjugates
The goal of this interventional study is to determine if scalp cooling (by the Paxman Scalp Cooling System) reduces the extent and severity of alopecia in participants with advanced solid tumours receiving ADC.
- Conditions
- Advanced or Metastatic Solid Tumour, Antibody-Drug Conjugate, Alopecia
- Trial name
- SCARLET-ICE (NCT07474558)
- Testing
- scalp cooling, photographs via the Belle.AI app, Antibody-Drug Conjugates
- Where
- 3 sites in Belgium
- Volunteers
- 102 people
- Sponsor
- Jules Bordet Institute
Frontal Fibrosing Alopecia
Trial Evaluating the Efficacy of Apremilast for the Treatment of Frontal Fibrosing Alopecia
This is open label single side study involvement 20 patient treated with Apremilast. Each enrolled patient may be evaluated at by a dermatologist using the Lichen Planopilaris Activity Index and Frontal Fibrosing Alopecia Index.
- Trial name
- NCT03422640
- Testing
- Apremilast
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Bellevue Dermatology
Psoriasis, Atopic Dermatitis
LANDSCAPE: Demographics and Treatment Patterns of Patients With Immune-Mediated Inflammatory Skin Diseases in Italian Clinical Practice
This multicenter retrospective observational registry study will collect existing clinical data from Italian centers to describe epidemiology, treatment patterns, clinical evolution, safety, and comorbidities in patients aged 12…
- Conditions
- Psoriasis, Atopic Dermatitis, Vitiligo, Alopecia Areata
- Trial name
- LANDSCAPE (NCT07336641)
- Testing
- Conventional Systemic Therapies, Biologic Therapies
- Where
- Italy
- Volunteers
- 20,000 people
- Sponsor
- Fondazione ISIDE
Androgenetic Alopecia
Minoxidil Response Testing in Males With Androgenetic Alopecia
Topical minoxidil is the most common drug used for the treatment of AGA in men. While topical minoxidil exhibits a good safety profile, the efficacy in the overall population remains relatively low i.e., 30-40% re-grow hair.
- Trial name
- NCT02198261
- Testing
- 5% minoxidil topical foam
- Where
- 5 sites in United States, Australia and 2 more
- Volunteers
- 300 people
- Sponsor
- Applied Biology, Inc.
Chemotherapy-induced Alopecia
"Impact of Chemotherapy-induced Alopecia on the Quality of Life of Women With Breast Cancer"
The main objective of this qualitative phenomenological study is to understand the impact of chemotherapy-induced alopecia, the quality of life of women with breast cancer from this experience.
- Trial name
- NCT02797223
- Testing
- Semi-structured interviews
- Where
- Spain
- Volunteers
- 15 people
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Androgenic Alopecia
Hydraderm for Androgenic Alopecia
The study will be focused on evaluating the use of hydradermabrasion on the scalp. The study aims to assess the effect of this treatment on scalp health and hair growth.
- Trial name
- NCT05426629
- Testing
- Venus Glow
- Where
- United States
- Sponsor
- University of Minnesota