Clinical trials: Alpha-Tocopherol
Prostate Cancer
Biomarker Study of Neoadjuvant Vitamin E in Patients With Locally Treatable Prostate Cancer
The purpose of this study is to find out if vitamin E can help treat prostate cancer. Vitamin E acts primarily as an anti-oxidant. By decreasing the oxidation in the cancer cell, the tumor cells may die.
- Trial name
- NCT00809458
- Testing
- Vitamin E
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- New Mexico Cancer Research Alliance
Endothelial Dysfunction
Impact of Smoking Cessation and γ-Tocopherol to Restore Vascular Endothelial Function
Cigarette smoking is a significant risk factor for cardiovascular disease (CVD) and is the leading cause of premature mortality in the US.
- Trial name
- NCT01314443
- Testing
- Nicotine Replacement Therapy (NRT), Gamma-Tocopherol, Smoking cessation
- Where
- United States
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- University of Connecticut
Mild, Allergic Asthma
Effect of Gamma Tocopherol Enriched Supplementation on Response to Inhaled LPS
To test the hypothesis that gamma tocopherol (vitamin E) supplement inhibits endotoxin induced airways inflammation in allergic asthmatics
- Trial name
- Vitalps (NCT02104505)
- Testing
- Gamma Tocopherol 700 mg capsules,
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- University of North Carolina, Chapel Hill
Allergic Asthma
Effect of Gamma Tocopherol Enriched Supplementation on Response to Inhaled O3 Exposure
To study the effects of 1200mg gamma tocopherol, a form of vitamin E, given daily on the response of the airway in mild asthmatics after exposure to ozone (O3)
- Trial name
- Gammoz (NCT02911688)
- Testing
- gamma tocopherol
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- University of North Carolina, Chapel Hill
Osteoradionecrosis
Management of Mandibular ORN: PENTO as Medical Treatment
Mandibular osteoradionecrosis, despite its low incidence, remains being the most problematic and irreversible complication after head and neck radiotherapy with no medical treatment to limit or reduce symptoms.
- Trial name
- PENTO (NCT02368457)
- Testing
- Pentoxifylline and Tocopherol
- Where
- Spain
- Volunteers
- 24 people
- Sponsor
- Hospital Vall d'Hebron
Fatty Liver
Treatment for Non-Alcoholic Fatty Liver With Different Doses of Vitamin E
Background: Non-alcoholic fatty liver disease (NAFLD) is an excess accumulation of fat in the liver cells. It is associated with obesity, high blood pressure, high cholesterol, and diabetes.
- Trial name
- NCT01792115
- Testing
- Vitamin E 200 IU/d, Vitamin E 400 IU/d, Vitamin E 800 IU/d
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Alzheimer's Disease
A Randomized, Clinical Trial of Vitamin E and Memantine in Alzheimer's Disease
The purpose of this study is to determine whether alpha-tocopherol, memantine (Namenda), or the combination will significantly delay clinical progression in mild to moderately demented patients with Alzheimer's disease compared…
- Trial name
- TEAM-AD (NCT00235716)
- Testing
- dl-alpha-tocopherol, Memantine
- Where
- 14 sites in United States, Puerto Rico
- Volunteers
- 613 people
- Sponsor
- US Department of Veterans Affairs
Burn
Vitamin E Supplementation in Burned Patients
A dietary antioxidant, alpha-tocopherol, will be used to potentially attenuate Vitamin E short- and long-term losses in plasma and adipose, reverse the oxidative stress of burn injury and, in the process, decrease the secondary…
- Trial name
- NCT01749371
- Testing
- Vitamin E
- Where
- 3 sites in United States
- Volunteers
- 27 people
- Sponsor
- The University of Texas Medical Branch, Galveston
Airway Inflammation, Asthma
A Study of Gamma Tocopherol-enriched Supplement on Lower Airway Responses to Inhaled Wood Smoke in Healthy Adults
Purpose: To determine the efficacy of 1400 mg gamma tocopherol-enriched supplement for mitigating inhaled wood smoke particle-induced airway inflammation in healthy adults with no more than mild asthma.
- Trial name
- SmokeyT (NCT03444298)
- Testing
- Gamma Tocopherol
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill