Clinical trials: Altered Mental Status
Altered Mental Status, Sepsis
Pre-hospital Ventilation Clinical Study
This study will collect and characterize ventilator use during patient care with a ZOLL 731 Series ventilator in a pre-hospital setting.
- Conditions
- Altered Mental Status, Sepsis, Heart Failure, Hemorrhage
- Trial name
- NCT05604430
- Testing
- 731 Series Ventilator
- Where
- 5 sites in United States
- Volunteers
- 500 people
- Sponsor
- Zoll Medical Corporation
Borderline Personality Disorder
Methylation Status of BDNF Gene After Dialectical Behavior Therapy in BPD
Borderline personality disorder (BPD) is a chronic and debilitating syndrome associated with considerable morbidity, mortality, and high rates of medical and psychiatric utilization services.
- Trial name
- NCT02134223
- Testing
- Dialectical behavior therapy, Treatment as Usual: any other drug or psychotherapy offered to participants, except DBT
- Where
- Taiwan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Mackay Memorial Hospital
Breast Cancer
Brain Imaging, Nutrition, and Cognition in Breast Cancer Survivors
Up to 78% of women diagnosed with breast cancer experience impairments in their cognitive function (e.g., frequent forgetfulness, slow processing speeds, and difficulties in concentration, multitasking and/or word retrieval) in…
- Trial name
- BRINC (NCT05122000)
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Ohio State University
Body Weight Change, Schizophrenia
Effects of Aripiprazole in Overweight Patients Treated With Olanzapine for Schizophrenia or Schizoaffective Disorder
The primary purpose of this study is to compare the affects of aripiprazole and olanzapine on weight change.
- Conditions
- Body Weight Change, Schizophrenia, Schizoaffective Disorder, Psychotic Disorder
- Trial name
- NCT00095524
- Testing
- Aripiprazole
- Where
- 32 sites in United States, Brazil and 1 more
- Volunteers
- 300 people
- Sponsor
- Otsuka Pharmaceutical Development & Commercialization, Inc.
Body Weight Changes
Pre Competition Weight Loss of Athletes
The objective of this observational study is to assess the long-term impact of a combined slow and rapid weight reduction strategy on the physiological performance, mental state, and sleep quality of male freestyle wrestlers.
- Trial name
- NCT06543017
- Testing
- Experimental group
- Where
- China
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Chengdu Sport University
Missing Posterior Occlusal Contact
Brain and Cognitive Function of Patients With RPD
To evaluate the influence of restoring lost posterior occlusal contacts with removable partial denture (RPD) on the brain activity and cognitive function in controlled type 2 diabetic patients
- Trial name
- NCT04554199
- Testing
- Flexible partial denture
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- National Research Centre, Egypt
Colorectal Cancer, Sleep Quality
Association of Sleep Quality and Mental Status With Early Recurrence and Prognosis of Colorectal Cancer
This is a prospective observational cohort study to explore the effects of sleep quality and mental status on early postoperative recurrence and prognosis in patients with colorectal cancer.
- Conditions
- Colorectal Cancer, Sleep Quality, Mental Status Change
- Trial name
- NCT06443996
- Where
- China
- Volunteers
- 500 people
- Sponsor
- Ma Yanlei
Delirium, Delirium in Old Age
Researching Efficient Approaches to Delirium Identification-Sustaining Effective Translation
The goal of this step-wedge trial is to test the implementation of daily nurse screening for delirium in routine care and its impact on outcomes and complications in hospitalized older adults admitted to 6 general…
- Conditions
- Delirium, Delirium in Old Age, Delirium With Dementia, Delirium Superimposed on Dementia
- Trial name
- READI-SET-GO (NCT05915377)
- Testing
- READI-SET GO UB-CAM delirium screening into EHR
- Where
- 2 sites in United States
- Volunteers
- 1,050 people
- Sponsor
- Penn State University
HIV/AIDS, Mental Impairment
Efficacy of Efavirenz 400mg vs. 600mg Combined With Lamivudine and Tenofovir in Treatment Naive HIV Infection
The present study will be a randomized controlled study in which 500 treatment-naive HIV patients will be randomized 1:1 to Efaviren 400mg v.s. 600mg combined with lamivudine and tenofovir.
- Trial name
- NCT04463784
- Testing
- Efavirenz 400Mg Oral Tablet, Efavirenz 600Mg Oral Tablet
- Where
- China
- Volunteers
- 500 people
- Sponsor
- Peking Union Medical College Hospital
Mental Impairment
Supported Employment Demonstration
The purpose of this study is to determine whether offering an evidence-based package of employment supports integrated with mental health services has a positive impact on employment and clinical recovery, and delays or…
- Trial name
- SED (NCT03682263)
- Testing
- Full Service, Basic Service
- Where
- 52 sites in United States
- Volunteers
- 3,000 people
- Sponsor
- Westat
Avitaminosis, Delirium, Dementia, Amnestic, Cognitive Disorders
Interaction of Cobalamin Status With Nitrous Oxide in Relation to Postoperative Cognitive Changes in the Elderly
Low cobalamin (vitamin B12) levels are frequent in the elderly. Most often they reflect a mild metabolic abnormality without clinical symptoms (subclinical cobalamin deficiency).
- Trial name
- NCT00212147
- Testing
- General anesthesia with nitrous oxide, General anesthesia without nitrous oxide
- Where
- 2 sites in United States
- Volunteers
- 444 people
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Sleep Bruxism, Sleep Disorder
Relationship Between Selected Parameters and Bruxism
Bruxism is a common phenomenon. It is estimated that its prevalence in the adult population is 8-31%. Bruxism occurring during sleep is the activity of the masticatory muscles that appear during sleep, which can be rhythmic or…
- Conditions
- Sleep Bruxism, Sleep Disorder, Psychosomatic Disorder, Pain
- Trial name
- WMU1/2019 (NCT04214561)
- Testing
- Polysomnography
- Where
- Poland
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Wroclaw Medical University
Cognitive Change, Metabolic Syndrome, Protection Against
Nutritional Intervention for Sustaining Health (NURISH) Trial
The goal of this clinical trial is to learn if increasing adherence to a Mediterranean-DASH Intervention for Neurodegenerative Delay (MIND) diet pattern improves brain and heart health relative to a healthy control diet in…
- Conditions
- Cognitive Change, Metabolic Syndrome, Protection Against, Diet, Healthy
- Trial name
- NCT06437860
- Testing
- MIND Diet, Control Diet
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- University of Illinois at Urbana-Champaign
Mental Impairment, Educational Problems
Helping Youth on the Path to Employment
Helping Youth on the Path to Employment (HYPE): Creating economic self-sufficiency, a randomized-controlled implementation efficacy hybrid trial, will test a manualized intervention combining educational and employment supports…
- Trial name
- HYPE (NCT04254562)
- Testing
- Weekly Meetings with a Supported Employment/Supported Education Specialist, Focused Skill and Strategy Training (FSST), Enhanced Services as Usual
- Where
- 3 sites in United States
- Volunteers
- 103 people, healthy volunteers welcome
- Sponsor
- University of Massachusetts, Worcester
Mental Status Change, Labor Pain
The Effect of Medical Clowning During Labor
Women during their first labor will be offered the assistance of a medical clown. Their experience will be compared after delivery with that of primiparae who were not helped by a medical clown.
- Trial name
- MedClown (NCT03167567)
- Testing
- Presence of a medical clown during labor
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- The Baruch Padeh Medical Center, Poriya
Altered Mental Status
Putting Electroencephalography (EEG) in the Emergency Department
The proposed study aims to test the impact of microEEG on clinical management (diagnosis and treatment) of emergency department patients with Altered Mental Status (AMS).
- Trial name
- NCT01671475
- Testing
- microEEG (Bio-Signal microEEG)
- Where
- 2 sites in United States
- Volunteers
- 149 people
- Sponsor
- Bio-Signal Group Corp.
Hypotension, Hypoxemia
Point of Care Ultrasound Evaluation in the Post-Anesthesia Unit
The purpose of this observational research study is to examine how point-of care ultrasound affects the workup and management of perioperative complications for specific clinical scenarios of low blood pressure (hypotension), low…
- Conditions
- Hypotension, Hypoxemia, Altered Mental Status, Urine Output Low
- Trial name
- NCT04410757
- Where
- United States
- Volunteers
- 128 people
- Sponsor
- Loma Linda University
Postoperative Cognitive Dysfunction
Ketamine and Changes of the Short Portable Mental Status Questionnaire
Cognitive changes are related to aging, affecting the performance of older patients in the solution of problems and the execution of tasks.
- Trial name
- SPMSQ-E (NCT02049411)
- Testing
- Ketamine, physiological solution
- Where
- Mexico
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Instituto Mexicano del Seguro Social
Delirium
Is Dexmedetomidine Associated With a Lower Incidence of Postoperative Delirium When Compared to Propofol or Midazolam in Cardiac Surgery Patients
The purpose of this chart review study is to determine whether the use of dexmedetomidine, a selective α2-adrenergic receptor agonist with sedative, analgesic, and antinociceptive properties, would be associated with a lower…
- Trial name
- NCT00417664
- Testing
- Dexmedetomidine, Propofol, Midazolam
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Stanford University
Cognitive Change, Total Knee Anthroplasty
Early Cognitive Changes After General Versus Spinal Anesthesia in Older Adults Undergoing Total Knee Arthroplasty
This prospective observational study investigated early postoperative cognitive changes in older adults undergoing elective total knee arthroplasty under general or spinal anesthesia.
- Trial name
- NCT07860593
- Testing
- General Anesthesia, Spinal Anesthesia with Bupivacaine
- Where
- Turkey (Türkiye)
- Volunteers
- 44 people
- Sponsor
- Haseki Training and Research Hospital