Clinical trials: Alveolar Bone Grafting
Tooth Loss
Treatment of Post-Extraction Dehisced Socket - A Case Series Study
PURPOSE The purpose of this case series is to clinically, radiographically and histologically evaluate the treatment of dehiscence defects in extraction sockets using a minimally-invasive GBR technique that involves the…
- Trial name
- OSTEO2 (NCT02980211)
- Testing
- Alveolar Ridge Reconstruction
- Where
- United States
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Gustavo Avila-Ortiz DDS, MS, PhD
Alveolar Bone Loss
Comparison Synthetic Hydroxyapatite and Inorganic Bovine Bone in Sinus Floor Elevation
This is set as prospective clinical trial to correlate histologically and radiologically the performance of four different bone grafts (synthetic hydroxyapatite alone, synthetic hydroxyapatite mixed with polylactic-polyglycolic…
- Trial name
- SYNBIO (NCT03077867)
- Testing
- sinus floor augmentation with bone graft
- Where
- Italy
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- International Piezosurgery Academy
Alveolar Bone Loss
Clinical, Radiographical, Histological Evaluation and Blood Flow Analysis of Alveolar Ridge Preservation
With alveolar ridge preservation (ARP) ridge resorption following extraction may be reduced. Several materials and techniques have been advocated for ARP.
- Trial name
- NCT05674331
- Testing
- Extraction site development technique, autogenous tooth bone graft, Socket seal technique
- Where
- Hungary
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Semmelweis University
Symphysis Onlay Bone Graft, Platelet Rich Fibrin
Effect of Symphysis Onlay Bone Graft, Injectable Platelet Rich Fibrin (I-PRF) and Xenograft on Horizontal Alveolar Ridge Augmentation in Esthetic Zone
The aim of the study: was to evaluate whether mandibular symphysis Onlay autogenous bone graft mixed with Injectable PRF could offer any advantages for patients undergoing horizontal alveolar ridge widening regarding increase…
- Conditions
- Symphysis Onlay Bone Graft, Platelet Rich Fibrin, Xenograft, Horizontal Alveolar Ridge Augmentation
- Trial name
- NCT06388837
- Testing
- Injectable Platelet Rich Fibrin, Xenograft
- Where
- Egypt
- Volunteers
- 12 people
- Sponsor
- October 6 University
Alveolar Ridge Enlargement
Leukocyte-platelet Rich Fibrin for Alveolar Ridge Preservation
After tooth extraction, there is a subsequent bone loss as a part of the natural healing of the tissue. Up to 50% of bone loss occurs during the first three months after extraction, jeopardizing a possible implant treatment.
- Trial name
- L-PRF (NCT05572242)
- Testing
- Premolar extraction and socked preservation with L-PRF, Premolar extraction and socked preservation with Xenogenic bone and collagen membrane.
- Where
- Chile
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Universidad de los Andes, Chile
Bone Loss, Bone Remodeling Disorder
Socket Preservation Using Dentin Graft Autogenous Dentin Graft With Collagen Sponge on Dental Implant Stability AUTOGENOUS TOOTH GRAFT WITH COLLAGEN SPONGE ON DENTAL IMPLANT STABILITY
The present study was performed to evaluate socket preservation using collagen sponge with autogenous dentin graft versus collagen sponge with de-mineralised freez-dried bone graft on dental implant stability
- Conditions
- Bone Loss, Bone Remodeling Disorder, Bone Resorption
- Trial name
- NCT06853392
- Testing
- Demineralized freeze dried allograft with collagen sponge, autogenous dentin graft with collagen sponge
- Where
- Egypt
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Faculty of Dental Medicine for Girls
Healing Wound, Alveolar; Wound
Ultrasound for Socket Healing Evaluation
The design is a single blinded, dual comparative study of ultrasound versus micro-CT/LASCA in one study group. Up to a total of 140 subjects registered will be recruited.
- Conditions
- Healing Wound, Alveolar; Wound, Alveolar Bone Loss, Image
- Trial name
- NCT06017193
- Where
- United States
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Alveolar Cleft, Alveolar Ridge Cleft
Evaluation of Shell Technique in Secondary Alveolar Cleft Grafting
This study aims to evaluate the sufficiency of Khoury shell technique for reconstruction of alveolar cleft. Khoury technique was carried out using cortical bone shell fixed away from alveolar bone using two micro-screws, which…
- Trial name
- Alveolar cleft (NCT06304376)
- Testing
- Alveolar ridge grafting
- Where
- Kuwait
- Volunteers
- 14 people
- Sponsor
- October 6 University
Alveolar Bone Loss, Dental Implant Failed
Simultaneous Implant Placement With Vertical and Horizontal Bone Augmentation
The purpose of this study was to report the clinical and radiographical outcomes of using autogenous cortical bone plates combined with sticky allogenic bone graft for augmenting maxillary anterior atrophic combined horizontal…
- Trial name
- NCT06313229
- Testing
- implant placement 6 months after ridge augmentation, implant placement Simultaneously with ridge augmentation
- Where
- Egypt
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Kafrelsheikh University
Alveolar Cleft Grafting
Combination of Bone Marrow Concentrate and Iliac Cancellous Bone Graft in Alveolar Cleft Grafting
The aim of this study will be to analyze the newly formed bone volume and density, 6 months after alveolar cleft grafting using iliac cancellous bone graft, with and without bone marrow concentrate.
- Trial name
- NCT04414423
- Testing
- bone marrow concentrate alveolar cleft grafting, Autogenous alveolar grafting
- Where
- 2 sites in Egypt
- Volunteers
- 18 people
- Sponsor
- Fayoum University
Laser Therapy, Periodontal Diseases
Odontogenic Graft Obtained From Human Tooth and Low Level Laser Therapy
This clinical trial aims to evaluate the effectiveness of an odontogenic graft obtained from extracted human teeth, with and without adjunctive low-level laser therapy (LLLT), on bone regeneration following posterior tooth…
- Conditions
- Laser Therapy, Periodontal Diseases, Bone Loss in Jaw, Alveolar Bone Loss
- Trial name
- NCT07615361
- Testing
- Autogenous Tooth-Derived Bone Graft, Low-Level Laser Therapy (LLLT)
- Where
- Turkey (Türkiye)
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Istanbul Saglik Bilimleri University
Periodontal Diseases, Periodontal Bone Loss
Clinical and Radiographic Assessment of Efficacy of Modified Minimally Invasive SurgicalTechnique (M-MIST) Alone and Combined With Enamel Matrix Proteins and Ox-derived Bone Graft in the Treatment of Single Bone Defects Between Teeth.
This study was performed to investigate the adjunctive clinical benefit of the application of enamel matric derivatives and xenograft with the modified minimally invasive surgical technique in the treatment of isolated intrabony…
- Trial name
- NCT07310732
- Testing
- modified minimally invasive surgical technique, modified minimally invasive surgical technique plus emdogain, modified minimally invasive surgical technique plus emdogain and xenograft
- Where
- India
- Volunteers
- 45 people
- Sponsor
- Rungta College of Dental Sciences and Research
Tooth Extraction, Bone Graft
Resorbable vs Non-resorbable Bone Substitute at Immediate Post-extractive Single Implants
This study compares two bone graft materials used when placing a dental implant right after tooth removal. One graft fully dissolves (GTO®), the other only partly (Apatos®).
- Conditions
- Tooth Extraction, Bone Graft, Alveolar Bone Loss, Dental Implant
- Trial name
- NCT07047131
- Testing
- GTO® (fully resorbable bone substitute), Apatos® (partially resorbable bone substitute)
- Where
- Spain
- Volunteers
- 50 people
- Sponsor
- Marco Esposito
Alveolar Bone Resorption
Bone Formation Maxillary Sinus Width
According to previous scientific evidence lining on biological concept of bone regeneration into the maxillary sinus, an observational study was set up to record possible (hypothesized) difference in bone formation between…
- Trial name
- NCT04830670
- Testing
- sinus floor elevation with lateral approach
- Where
- 3 sites in Italy
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- International Piezosurgery Academy
Dental Implant
Autogenous Tooth Graft for Ridge Augmentation
This study is designed to evaluate the clinical and radiographical outcome of tooth shell for alveolar ridge reconstruction in maxilla as an alternative to traditional autologous bone shell graft.
- Trial name
- NCT06416605
- Testing
- Maxillary Alveolar Ridge Augmentation
- Where
- Egypt
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Alveolar Ridge Preservation, Post Extraction Alveolar Bone Resorption
Comparison of Demineralized and Mineralized Dentin Grafts in Ridge Preservation
This clinical investigation aims to assess how two different allogeneic dentin graft materials - one de-mineralized and the other mineralized - influence bone preservation following extraction of a single upper posterior tooth.
- Trial name
- DDG-ARP (NCT07242313)
- Testing
- Demineralized Allogeneic Dentin Graft, Mineralized Allogeneic Dentin Graft
- Where
- Egypt
- Volunteers
- 45 people
- Sponsor
- Kafrelsheikh University
Alveolar Bone Loss
Autogenous Demineralized Dentin Block Graft Versus Autogenous Bone Block Graft for Alveolar Ridge Preservation
The aim of this trial is to compare the effect of autogenous demineralized dentin block graft (ADDBG) versus autogenous bone block graft (ABBG) harvested from maxillary tuberosity on alveolar ridge preservation after extraction…
- Trial name
- NCT05347017
- Testing
- Alveolar ridge preservation using autogenous demineralized dentin block graft, Alveolar ridge preservation using autogenous bone block graft
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cairo University
Platelet-rich Fibrin, Bone Substitutes
Horizontal Bone Augmentation of Alveolar Ridge
The objective of this randomized controlled clinical trial was to evaluate the effects of particulate xenogeneic bone grafts associated with autogenous bone graft or Leukocyte-and-Platelet-Rich Fibrin (L-PRF) for horizontal…
- Conditions
- Platelet-rich Fibrin, Bone Substitutes, Atrophic Maxilla, Cone-beam Computed Tomography
- Trial name
- NCT06420713
- Testing
- Horizontal Bone Augmentation of Alveolar Ridge, Groups, Dental Implants
- Where
- Brazil
- Volunteers
- 28 people
- Sponsor
- University of Sao Paulo
Alveolar Cleft
Metformin and Alveolar Cleft
Completed medical history will take for all patients. All patients' guardians were informed about the procedure, the possible postoperative complications, and requested to sign an informed consent that was translated into Arabic…
- Trial name
- NCT07536620
- Testing
- metformin group
- Volunteers
- 36 people
- Sponsor
- Fayoum University
Alveolar Ridge Preservation, Dental Extraction
Mix of Demineralized Freeze-Dried Bone Allograft and Deproteinized Bovine Bone Mineral: a Possible Solution for Alveolar Ridge Preservation?
The purpose of the study is to compare a new grafting material for alveolar ridge preservation to a commonly used and well studied material. Alveolar ridge dimensions as well as histology will be compared.
- Conditions
- Alveolar Ridge Preservation, Dental Extraction, Bone Graft
- Trial name
- NCT06275789
- Testing
- Alveolar ridge preservation
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Nova Southeastern University