Clinical trials: Alveolar Cleft
Cleft Lip and Palate, Unilateral Cleft Lip
Influence of Presurgical Orthodontic Molding on the Growth of Newborns With Unilateral Cleft Lip Palate
Orofacial clefts are the second most common birth deformity and vary in etiology and phenotype, e.g. isolated cleft palate, cleft lip or cleft lip palate.
- Trial name
- NCT05081258
- Testing
- passive Alveolar Molding, Nasoalveolar Molding
- Where
- Germany
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- University of Erlangen-Nürnberg
Alveolar Bone Grafting
Evaluation of Computer-Guided Secondary Alveolar Cleft Bone Grafting With and Without Platelet-Rich Fibrin
This study aims at investigating the role of platelet-rich fibrin in alveolar cleft secondary grafting. This grafting is done from the patient's chin using a computer-guided stent that is customized for each patient, and the…
- Trial name
- NCT05422196
- Testing
- Platelet-rich fibrin
- Where
- Egypt
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Alveolar Cleft
Alveolar Cleft Reconstruction With Cortical-Shells
The main goal of the secondary alveolar bone grafting (SABG) for alveolar clefts is the rehabilitation of the disorganized maxilla, aiming to stabilize the maxillary foundation as a solid functional mass that would abort growth…
- Trial name
- NCT06585566
- Testing
- Cortical-shell graft
- Where
- 2 sites in Egypt
- Volunteers
- 7 people
- Sponsor
- Beni-Suef University
Alveolar Cleft
Partial Maxillary Expansion With Post Grafting Expansion vs. Pre Full Maxillary Expansion in Secondary Alveolar Cleft
Intermediate grafting with both pre- and post- grafting maxillary expansion with time span after grafting 6-8 weeks for consolidation and final retention for 3 months after finalization of expansion will get the advantages of…
- Trial name
- NCT05941988
- Testing
- pre grafting partial maxillary expansion with post grafting expansion
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cairo University
Cleft Lip and Palate
Progression of Grafted Bone Density in Cleft Alveolus
The patients with unilateral and bilateral cleft lip and palate received alveolar bone graft surgery. Two time points of cone beam CT were taken for all the patients: post-operative 6 months, and post-operative 2 years.
- Trial name
- CDAABG (NCT04987190)
- Testing
- alveolar bone graft
- Where
- Taiwan
- Volunteers
- 40 people
- Sponsor
- Chang Gung Memorial Hospital
Evaluate CBCT Protocols in Subjective Image Quality
Validation of X-ray Protocols in Cleft Children
Children born with an alveolar cleft receive bone grafts for improved function and aesthetics. The cleft area is radiologically examined before and post bone graft.
- Trial name
- NCT05351372
- Testing
- Ultra-low dose protocol, Standard dose protocol
- Where
- Sweden
- Volunteers
- 72 people
- Sponsor
- Karolinska Institutet
Cleft Lip and Palate
Alveolar Cleft Hard- and Soft Tissue Reconstruction With an Autogenous Tooth Derived Particulate Graft
The present study aims at clinical and radiographic evaluation of the safety and efficacy of Bonmaker ATB powder combined with a novel split thickness papilla curtain flap in the treatment of alveolar cleft defects.
- Trial name
- NCT05971914
- Testing
- Autogenous tooth derived particulate graft and a novel split thickness papilla curtain flap
- Where
- Hungary
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Semmelweis University
Cleft; Alveolar Process
Evaluation of MPM Prepared From Allogenic Bone Graft in Alveolar Cleft Closure: A Prospective Randomized Clinical Trial
The aim of this trial is to figure out the efficiency of Mineralized Plasmatic Matrix prepared from allogenic bone graft on cleft alveolus and oro-nasal fistula closure, adequate bone volume and acceptable density at the site of…
- Trial name
- NCT03420287
- Testing
- MPM Prepared From Allogenic Bone Graft, Autogenous bone
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Cairo University
Cleft Palate
Effect of Cleft Palate Repair Using Alveolar Extension Technique on Eruption and Growth
This study aimed to evaluate clinically the "Alveolar extension" technique for palatoplasty in cases of primary closure of cleft palate regarding its effect on: 1. Eruption of Primary dentition. 2.
- Trial name
- NCT05286398
- Testing
- Palatoplasty, Addition silicone impression
- Where
- Egypt
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Unilateral Alveolar Cleft of Maxilla
Bone Marrow Aspirate Concentrate With Bovine Bone Graft for Unilateral Alveolar Cleft Reconstruction
This randomized clinical trial evaluated whether adding autologous bone marrow aspirate concentrate (BMAC) to a bovine-derived bone graft improves healing and bone regeneration in patients undergoing reconstruction of a…
- Trial name
- NCT07786259
- Testing
- BMAC-Enriched Bovine Bone Grafting, Bovine Bone Grafting
- Where
- Egypt
- Volunteers
- 16 people
- Sponsor
- Tanta University
Cleft Lip and Palate
Liposomal Bupivacaine Use in Alveolar Bone Graft Patients
The goal of this clinical trial is to learn if a pain medication called liposomal bupivacaine (brand name EXPAREL®) with epinephrine will provide better pain control, increased activity, and reduced use of opioids compared with…
- Trial name
- NCT06284434
- Testing
- Liposomal Bupivacaine, Bupivacain, Epinephrine
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Kerry O'Rourke
Cleft Lip, Congenital Nose Malformation
Fabrication of Sequential Naso-Alveolar Molding Appliances in the Treatment of Cleft Lip/Nose Deformities
There is a robust body of research suggesting that the use of pre-surgical orthopedic devices prior to definitive cleft lip/nose repair results in significant improvement of facial aesthetics with long term follow up.
- Conditions
- Cleft Lip, Congenital Nose Malformation, Deformity, Nose Deformities, Acquired
- Trial name
- NCT04334590
- Testing
- Cleft Lip/Nose Repair without PSIO, Presurgical Infant Orthopedic Therapy
- Where
- United States
- Sponsor
- Johns Hopkins University
Alveolar Cleft
Xenografts With Platelet-rich Fibrin Versus Autogenous Bone in Alveolar Cleft Grafting
this work aims to evaluate xenografts mixed with PRF versus autogenous bone graft in alveolar cleft grafting.
- Trial name
- NCT04693741
- Testing
- secondary alveolar bone graft, Harvesting of the autogenous bone graft, Preparation of PRP
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Assiut University
Alveolar Cleft Operated on an Alveolar Bone Graft
Alveolar Bone Graft Cortical Nasal Floor
Alveolar bone graft is one of the main step of the surgical care of the patients who are suffering from cleft lip and palate. They are usually performed before the lateral incisor eruption, at about 5 years old and using…
- Trial name
- NCT03883373
- Testing
- alveolar bone graft with cancellous bone and a cortical block, alveolar bone graft with cancellous bone only
- Where
- France
- Volunteers
- 302 people
- Sponsor
- University Hospital, Montpellier
Alveolar Cleft Grafting
Combination of Bone Marrow Concentrate and Iliac Cancellous Bone Graft in Alveolar Cleft Grafting
The aim of this study will be to analyze the newly formed bone volume and density, 6 months after alveolar cleft grafting using iliac cancellous bone graft, with and without bone marrow concentrate.
- Trial name
- NCT04414423
- Testing
- bone marrow concentrate alveolar cleft grafting, Autogenous alveolar grafting
- Where
- 2 sites in Egypt
- Volunteers
- 18 people
- Sponsor
- Fayoum University
Cleft Lip and Palate
Evaluation of the Clinical Effectiveness of Naso-alveolar Molding (NAM) Versus Computer Aided Design NAM (CAD/NAM) in Infants With Bilateral Cleft Lip and Palate: A Randomized Clinical Trial
Bilateral cleft lip and palate neonates will be randomly assigned to one of two groups: (gp1 presurgical Naso-alveolar molding (NAM) using Grayson method, gp 2 computer aided design NAM (CAD/NAM).
- Trial name
- NCT02881606
- Testing
- Naso-alveolar molding (NAM), Computer aided design NAM (CAD/NAM)
- Where
- Egypt
- Volunteers
- 28 people
- Sponsor
- Cairo University
Alveolar Cleft, Alveolar Ridge Cleft
Evaluation of Shell Technique in Secondary Alveolar Cleft Grafting
This study aims to evaluate the sufficiency of Khoury shell technique for reconstruction of alveolar cleft. Khoury technique was carried out using cortical bone shell fixed away from alveolar bone using two micro-screws, which…
- Trial name
- Alveolar cleft (NCT06304376)
- Testing
- Alveolar ridge grafting
- Where
- Kuwait
- Volunteers
- 14 people
- Sponsor
- October 6 University
Alveolar Cleft
Evaluation of Secondary Alveolar Cleft Reconstruction
The rehabilitation of the disorganized maxilla is the primary objective of secondary alveolar bone grafting (SABG) for alveolar clefts, as the bony reconstruction of the discontinued maxillary arch would permit proper anterior…
- Trial name
- NCT06621719
- Testing
- Alveolar Cleft Reconstruction
- Where
- Egypt
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Beni-Suef University
Cleft Lip and Palate
Cost Effectiveness in Alveolar Bone Grafting in Patients With Cleft Lip and Palate
The purpose of this trial is to evaluate if the use of Bone Morphogenic Protein(BMP)/Demineralized Bone Matrix (DBM) versus the use of autologous Iliac Crest Bone Graft (ICBG) will result in an increase in total cost…
- Trial name
- NCT04234971
- Testing
- Intervention group (DBM/BMP), Control group(autologous ICBG)
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- The University of Texas Health Science Center, Houston
Alveolar Cleft Grafting
Alveolar Cleft Grafting Using Two Different Alloplastic Grafts
P-patients with unilateral alveolar clefts I-purabone with -β-tricalcium phosphate graft C-β-tricalcium phosphate graft alone O-clinical out come Outcome name Measurement device Measurement unit Esthetic satisfaction (Primary…
- Trial name
- NCT03016793
- Testing
- Puerarin, β- tricalcium phosphate, β- tricalcium phosphate alone
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cairo University