Clinical trials: Alveolar Hypoventilation
Obesity Hypoventilation Syndrome (OHS)
Study of AD981 Versus Placebo in Obesity Hypoventilation Syndrome
This is a randomized, double blind, placebo-controlled, cross-over, phase II, single center efficacy study of AD981 in patients with obesity hypoventilation syndrome documented by polysomnography (PSG) and transcutaneous…
- Trial name
- ATOHS (NCT05448443)
- Testing
- AD981
- Where
- Italy
- Volunteers
- 15 people
- Sponsor
- Istituto Auxologico Italiano
Obesity Hypoventilation Syndrome (OHS)
Obesity in Sleep Medicine - Focusing on OHS Phenotypes
This study focuses on a comprehensive examination of obese patients with sleep-related breathing disorders including patients with OSA, sleep hypoventilation and OHS.
- Trial name
- NCT04570540
- Testing
- Sleep Study, Pulmonary Function Test, Hypercapnic ventilatory response
- Where
- Germany
- Volunteers
- 82 people
- Sponsor
- Wissenschaftliches Institut Bethanien e.V
Acute Respiratory Failure, Hypercapnic Respiratory Failure
Efficacy of Volume Ventilation in Patients With Acute Respiratory Failure at Risk of Obstructive Apneas or Obesity Hypoventilation
This study compares a volume targeted pressure support non-invasive ventilation with an automatic PEP regulation (AVAPS-AE mode) to a pressure support non-invasive ventilation (S/T mode) in patients with acute hypercapnic…
- Conditions
- Acute Respiratory Failure, Hypercapnic Respiratory Failure, Respiratory Acidosis, Obesity
- Trial name
- VONIVOO (NCT04131660)
- Testing
- AVAPS-AE mode during NIV, S/T mode during NIV
- Where
- France
- Volunteers
- 14 people
- Sponsor
- University Hospital, Rouen
Hypoventilation, Hypoxia
Using Capnography to Reduce Hypoxia During Pediatric Sedation
The investigators hypothesize that the addition of capnography during moderate sedation will improve recognition of hypoventilation and apnea.
- Trial name
- NCT01463527
- Testing
- Nellcor NPB-70 Capnograph
- Where
- United States
- Volunteers
- 167 people
- Sponsor
- Yale University
Type II Respiratory Failure, Hypercapnic Respiratory Failure
Post-Extubation High-Flow Nasal Cannula Versus Non-Invasive Ventilation in Type II Respiratory Failure
Acute hypercapnic respiratory failure is characterized by elevated arterial carbon dioxide levels and commonly occurs in patients with chronic respiratory diseases.
- Trial name
- NCT06918288
- Testing
- High-Flow Nasal Cannula (HFNC), Non-Invasive Ventilation (NIV)
- Where
- Egypt
- Volunteers
- 200 people
- Sponsor
- Benha University
Hypoventilation
Capnography Monitoring in the Bronchoscopic Sedation
Procedure sedation of flexible bronchoscopy (FB) comforts patients undergoing FB. Hypoventilation during FB is a concern. The investigators investigate the feasibility of monitoring capnography in FB sedation.
- Trial name
- NCT02848118
- Testing
- A nasal-oral cannula of capnography, Observer Assessment of Alertness and Sedation scale
- Where
- Taiwan
- Volunteers
- 124 people
- Sponsor
- Chang Gung Memorial Hospital