Clinical trials: Alzheimer Dementia
Knowledge, Attitudes, Practice, Burnout, Caregiver
Online Training & Certification for Competency in Dementia Friendly Hospital Care
This research study will evaluate the CARES Dementia-Friendly Hospitals online training and certification program for Allied Health Workers (nursing assistants, dietary aides, housekeeping employees, hospital transporters…
- Conditions
- Knowledge, Attitudes, Practice, Burnout, Caregiver, Job Satisfaction
- Trial name
- NCT04182282
- Testing
- CARES Dementia-Friendly Hospitals Online Training and Certification Program
- Where
- United States
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- HealthCare Interactive, Inc.
Alzheimer's Disease, Amnestic Mild Cognitive Impairment
Brain Uptake and Safety With Probable Alzheimer's Disease, Amnestic Mild Cognitive Impairment and Healthy Volunteers
Study to Assess Brain Uptake and Safety of AH110690 (18F) Injection in Subjects with Probable Alzheimer's Disease, Amnestic Mild Cognitive Impairment and Healthy Volunteers.
- Trial name
- ALZ201 (NCT00785759)
- Testing
- AH110690 (18F) Injection
- Where
- Norway
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- GE Healthcare
Alzheimer's Disease
Brain Amyloid and Vascular Effects of Eicosapentaenoic Acid
The number of Americans diagnosed with Alzheimer's disease (AD) is expected to triple by 2050. Compared to the general population, Veterans have a greater risk of AD, likely in part due to their increased incidence of traumatic…
- Trial name
- BRAVE-EPA (NCT02719327)
- Testing
- icosapent ethyl (IPE)
- Where
- United States
- Volunteers
- 131 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Alzheimer Disease
Feasibility and Interest of the 3D Ephemeris for Temporal Orientation in Alzheimer's: Pilot Study
In geriatric care, occupational therapists use validated tools to assess abilities and performance, identifying deficiencies and proposing rehabilitation programs.
- Trial name
- E3D (NCT06824142)
- Testing
- Evaluate in real-life conditions the effectiveness of an adapted external aid as a tool to support temporal orientation rehabilitation for individuals with Alzheimer's disease or related dementias in
- Where
- France
- Volunteers
- 20 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Alzheimer Disease
Emotion and Attention in Alzheimer's Disease (ATEMMA)
The main purpose of this study is to investigate the existence of emotional attention impairments in Alzheimer's Disease, in correlation with amygdala and attention networks alterations.
- Trial name
- ATEMMA (NCT03971994)
- Testing
- Facial expression recognition task
- Where
- France
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- University Hospital, Grenoble
Prevention
Management of Dementia With Olive Oil Leaves - GOLDEN
Mild Dementia (Mild Dementia) is a state of mind disorder (memory, reason, attention, concentration, time orientation) with difficulty in the complex activities of everyday life (bank accounts, shopping, transportation, etc).The…
- Trial name
- GOLDEN (NCT04440020)
- Testing
- Beverage of Olive Oil Leaves, Mediterranean Diet
- Where
- Greece
- Volunteers
- 100 people
- Sponsor
- Aristotle University Of Thessaloniki
Mild Cognitive Impairment, Alzheimer Disease
Discovery of Novel Biomarkers That Will Lead to the Early Detection of Alzheimer's Disease
This study will perform a targeted metabolic analysis in blood and urine samples from subjects attending the Baylor AT\&T Memory Center.
- Trial name
- BVB (NCT03136679)
- Where
- United States
- Volunteers
- 95 people, healthy volunteers welcome
- Sponsor
- Baylor Research Institute
Dementia, Mixed, Dementia of Alzheimer Type
REACH Hope Intervention for Dementia and TBI Caregivers
This three-year randomized clinical trial will evaluate a behavioral intervention for caregivers of Veterans with traumatic brain injury (TBI) and Alzheimer's dementia or mixed Dementia (AD/MD) to reduce caregiver depression…
- Conditions
- Dementia, Mixed, Dementia of Alzheimer Type, TBI (Traumatic Brain Injury)
- Trial name
- REACH Hope (NCT04969796)
- Testing
- REACH Hope
- Where
- United States
- Volunteers
- 110 people
- Sponsor
- Memphis VA Medical Center
Alzheimer Disease, Psychomotor Agitation
Alzheimer's in Long-Term Care--Treatment for Agitation
The purpose of this study is to see if a medication called prazosin is useful in the treatment of agitation and aggression in persons with Alzheimer's disease (AD) and other types of dementia in late life.
- Trial name
- NCT00161473
- Testing
- prazosin
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- University of Washington
Cataracts, Alzheimer's Disease
Cataract Removal and Alzheimer's Disease
Two very common aging-related diseases in older adults are Alzheimer's disease (AD) and cataracts. In elderly adults, these two diseases frequently occur in the same person.
- Trial name
- NCT00921297
- Testing
- Immediate Cataract Surgery
- Where
- 2 sites in United States
- Volunteers
- 122 people
- Sponsor
- University Hospitals Cleveland Medical Center
Healthy, Prodromal Alzheimer's Disease
Exploring the Gut-Brain Axis in Ageing and Neurodegeneration
Neurodegenerative diseases are a major health concern due to their growing societal implications and economic costs. The identification of early markers of pathogenic mechanisms is one of the current main challenges.
- Conditions
- Healthy, Prodromal Alzheimer's Disease, Parkinson Disease, Multiple Sclerosis
- Trial name
- GutBrain (NCT05934188)
- Testing
- Magnetic Resonance Imaging, Neuropsychological protocol, Eating habits
- Where
- 3 sites in Italy
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- IRCCS San Camillo, Venezia, Italy
Alzheimer's Disease, Mild Cognitive Impairment
NMDA-enhancing Agent for Treatment of Mild Cognitive Impairment and Mild Alzheimer's Disease
NMDA activation plays an important role in learning and memory. NMDA receptors were found to decrease in the frontal lobe and hippocampus of Alzheimer's disease and mild cognitive function impairment.
- Trial name
- NCT01600469
- Testing
- DAOI-B
- Where
- Taiwan
- Volunteers
- 86 people
- Sponsor
- Chang Gung Memorial Hospital
Down Syndrome, Alzheimer's Disease
Down Syndrome Biomarker Initiative (DSBI)
Non-randomized natural history study involving 12 subjects with Down Syndrome, who are aged 30-60 years old. This study will observe 3 different groups: four non-demented subjects between ages 30-40 years old, four non-demented…
- Trial name
- DSBI (NCT02141971)
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Michael Rafii
Alzheimer's Disease (AD)
Biomarkers in a Candian Memory Clinic
This is a prospective, observational, case control study in a real-world cohort of patients referred by a primary care physician to a tertiary memory clinic for cognitive concerns.
- Trial name
- BioMIND (NCT06843109)
- Where
- Canada
- Volunteers
- 100 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Fatigue, Cancer
Exercise for Young Adults With Cancer
Over the past decade, importance of supportive care in cancer treatment of young cancer patients has increased. However, most common cancer-related side effects, such as physical deconditioning, psychological problems…
- Conditions
- Fatigue, Cancer, Physical Activity, Exercise
- Trial name
- YOUEX (NCT05613699)
- Testing
- Exercise - Social Media, Exercise - App, Exercise - closed to patients residence
- Where
- Germany
- Volunteers
- 106 people
- Sponsor
- University Hospital Heidelberg
Anosognosia, Alzheimer's Disease
Functional Magnetic Resonance Imaging (fMRI) of Anosognosia in Amnestic Mild Cognitive Impairment (MCI) and Alzheimer's Disease (AD)
This is a three year fMRI study conducted at the University of Wisconsin (UW) Hospital and the William. S. Middleton VA Hospital.
- Conditions
- Anosognosia, Alzheimer's Disease, Mild Cognitive Impairment
- Trial name
- NCT00908999
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Alzheimer's Disease
Lu AE58054 Added to Donepezil for the Treatment for Moderate Alzheimer's Disease
The purpose of this study is to accept or reject the hypothesis that Lu AE58054 improves cognition and functional outcomes in patients with moderate Alzheimer's Disease, already in treatment with donepezil.
- Trial name
- NCT01019421
- Testing
- Lu AE58054
- Where
- 51 sites in Australia, Canada and 5 more
- Volunteers
- 278 people
- Sponsor
- H. Lundbeck A/S
Alzheimer Disease
Validation of a Remediation Method for Memory Disorders Using Motor and Emotional Encoding in Patients With Alzheimer's Disease
Memories are more robust when they are multitraced. This means that the more a piece of information is mediated by different sensory inputs, the more resistant it is to being forgotten.
- Trial name
- ADAE (NCT06105047)
- Testing
- Cognitive tests
- Where
- 3 sites in France
- Volunteers
- 40 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Agitation and Aggression in Alzheimer's Disease
A Study of Pimavanserin for the Treatment of Agitation and Aggression in Subjects With Alzheimer's Disease
To evaluate the safety and tolerability of pimavanserin over 52 weeks of treatment in subjects with probable AD who have symptoms of agitation and aggression
- Trial name
- NCT03118947
- Testing
- Pimavanserin
- Where
- 28 sites in United States, Chile and 3 more
- Volunteers
- 79 people
- Sponsor
- ACADIA Pharmaceuticals Inc.
Alzheimer's Disease
Improved Diagnosis of Alzheimer's Disease Using Magnetoencephalography (MEG)
The current study is intended to enrich and extend the database of Alzheimer's Disease (AD) and healthy control (HC) MEG scans and will include patients meeting DSM-IV-TR criteria for dementia of Alzheimer's type, and age- and…
- Trial name
- NCT00973518
- Where
- 2 sites in United States
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Orasi Medical, Inc.
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