Clinical trials: Amblyopia
Amblyopia
Bilateral Transcranial Direct Current Stimulation and Ocular Occlusion for Adults With Amblyopia
A prospective interventional study is expected to be conducted, to test a possible new treatment for amblyopia (lazy eye syndrome).
- Trial name
- NCT05016830
- Testing
- Bilateral transcranial direct current stimulation
- Where
- Chile
- Volunteers
- 12 people
- Sponsor
- University of Chile
Amblyopia
Will Perceptual Learning Via Video Game Playing Improve Visual Acuity Stereopsis & Fixation Stability in Mild Amblyopes?
Contrast balanced dichoptic videogame training has been found to improve sensory functions in adults with amblyopia; best corrected distance visual acuity (BCVA) and stereopsis, but its effect on motor function, namely amblyopic…
- Trial name
- NCT02995174
- Testing
- Dichoptic video game in an i-Pod touch device, Video game in an i-Pod touch device
- Where
- Hong Kong
- Volunteers
- 23 people
- Sponsor
- The Hong Kong Polytechnic University
Amblyopia ex Strabismus, Amblyopia ex Anisometropia
Neurovascular Coupling in Subjects With Amblyopia
Amblyopia is a developmental condition that is characterized by reduced vision of the eye due to the presence of a sensory impediment during visual development, such as strabismus (ocular misalignment) or anisometropia (unequal…
- Trial name
- NCT01746693
- Testing
- Dynamic Vessel Analyzer, Laser Doppler Velocimetry, 7-Tesla MRI
- Where
- Austria
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Amblyopia
Virtual Reality Game Playing in Amblyopia Therapy
Background: "Amblyopia is a neurodevelopmental disorder in both monocular and binocular functions and it extends even beyond the primary visual integration centers", therefore, amblyopia is not a "lazy eye" but it is a "lazy…
- Trial name
- NCT04261868
- Testing
- Virtual Reality, Patching
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Hamideh Sabbaghi
Amblyopia, Strabismus
Amblyopia and Strabismus Detection Using a Pediatric Vision Scanner
The purpose of this project is to compare the performance of the Pediatric Vision Scanner (PVS) with the Gold Standard Examination to determine the effectiveness of the PVS at detecting amblyopia and strabismus.
- Trial name
- NCT01832883
- Testing
- Pediatric Vision Scanner
- Where
- United States
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Rebiscan, Inc.
Amblyopia
A Randomized Trial to Evaluate Sequential vs Simultaneous Patching
A randomized trial to determine whether simultaneous treatment with spectacles and patching has an equivalent VA outcome compared with sequential treatment, first with spectacles alone followed by patching (if needed), for…
- Trial name
- ATS22 (NCT04378790)
- Testing
- Patching, Glasses
- Where
- 68 sites in United States
- Volunteers
- 544 people
- Sponsor
- Jaeb Center for Health Research
Amblyopia
Clinical Data Registry of Amblyopia Patients on Luminopia Treatment
Amblyopia is the most prevalent cause of reduced monocular visual acuity in children and young adults, with estimates of prevalence ranging from 1% to 5%.
- Trial name
- NCT06429280
- Testing
- N/A this is an observational study of Standard of Care
- Where
- 13 sites in United States
- Volunteers
- 500 people
- Sponsor
- Luminopia
Amblyopia
A Study on the Efficacy and User Experience of Gamified Intervention for Children With Anisometropic Amblyopia
This project addresses the challenge of visual function intervention in children with monocular anisometropic amblyopia. It employs two innovatively designed digital games combined with occlusion therapy to conduct visual…
- Trial name
- NCT07472231
- Testing
- Serious touchscreen game combined with occlusion, Augmented reality game combined with occlusion, Occlusion therapy
- Where
- China
- Volunteers
- 66 people
- Sponsor
- Xinhua Hospital, Shanghai Jiao Tong University School of Medicine
Amblyopia Unilateral, Amblyopia Functional
AR Training in Adults With Unilateral Amblyopia
This is a single-center, non-randomized controlled trial to compare the effectiveness of binocular AR training with patching for the treatment of adults with unilateral amblyopia.
- Trial name
- NCT06704737
- Testing
- AR training, Patching
- Where
- China
- Volunteers
- 48 people
- Sponsor
- Eye & ENT Hospital of Fudan University
Amblyopia
Is Non-cycloplegic Photorefraction Applicable for Screening Refractive Risk Factors of Amblyopia?
Purpose: : This study was performed to compare the accuracy of non-cycloplegic photorefraction with cycloplegic refraction in detection of refractive amblyopia risk factors and determine some corresponding beneficial cut points.
- Trial name
- NCT01308307
- Testing
- photorefraction
- Where
- Iran
- Volunteers
- 185 people
- Sponsor
- Shahid Beheshti University of Medical Sciences
Strabismic Amblyopia, Refractive Amblyopia
Comparative Validation of "Blinq" and "2WIN" Vision Screeners
After 28 years of development, the binocular birefringence screener ("blinq," "Rebion") was commercially released. It need to be validated with AAPOS (American Association for Pediatric Ophthalmology and Strabismus) criteria in…
- Conditions
- Strabismic Amblyopia, Refractive Amblyopia, Strabismus
- Trial name
- NCT04195711
- Testing
- objective pediatric vision screen, "blinq,"
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Alaska Blind Child Discovery
Balance Control
Impact of Physical Activities on Balance in Patient With Strabismic Amblyopia
The aim of this study is to determine the effect of physical activities on balance in patient with amblyopia after strabismus surgery.
- Trial name
- NCT06758063
- Testing
- exercises therapy
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Amany Refaat Mohamed Abdel Wahid
Refractory Amblyopia
Evaluation of Echothiophate in Pediatric Patients With Refractory Amblyopia
The goal of this clinical trial is to see if a medicine called echothiophate iodide (Phospholine Iodide) can help treat children with refractory amblyopia.
- Trial name
- NCT07554131
- Testing
- Echothiophate Iodide 0.125% Ophthalmic Solution
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Oklahoma
Amblyopia
Morning Versus Evening Patching in Childhood Amblyopia
To determine whether the time of day at which daily occlusion therapy is administered-morning, with 2 hours of patching completed within 07:00-10:00, versus evening, with 2 hours completed within 17:00-20:00-affects visual-acuity…
- Trial name
- NCT07294599
- Testing
- eye-patching
- Where
- 2 sites in Jordan
- Volunteers
- 84 people
- Sponsor
- Yarmouk University
Amblyopia
Trial Comparing Part-time Versus Full-time Patching for Severe Amblyopia
The goals of this study are: To determine whether the visual acuity improvement obtained with part-time (6 hours) patching is equivalent to the visual acuity improvement obtained with full-time patching (all or all but one waking…
- Trial name
- NCT00094744
- Testing
- Eye patch
- Where
- United States
- Volunteers
- 175 people
- Sponsor
- Jaeb Center for Health Research
Amblyopia, Anisometropia
The Effect of Light Deprivation on Visual Functions in Adult Amblyopes
Amblyopia is a significant health problem, affecting up to 4% of the population in the United States. Amblyopia, commonly known as "lazy eye," is a developmental visual disorder in which one or both eyes suffer from poor vision…
- Conditions
- Amblyopia, Anisometropia, Visual Impairment
- Trial name
- NCT02799836
- Testing
- Blindfold
- Sponsor
- Boston Children's Hospital
Amblyopia, Refractive Errors
Vision Screening for the Detection of Amblyopia
INTRODUCTION. Amblyopia is defined as the loss of visual acuity (VA) in one or both eyes, without any obvious structural or pathological anomalies.
- Conditions
- Amblyopia, Refractive Errors, Anisometropia, Strabismus
- Trial name
- NCT01430247
- Testing
- Amblyopia screening
- Where
- Croatia
- Volunteers
- 7,000 people
- Sponsor
- Mladen Busic
Amblyopia
Noninvasive Brain Stimulation in Adult Amblyopia
The goal of this randomized controlled trial is to investigate the effectiveness of non-invasive brain stimulation in treating adults with amblyopia. The main questions it aims to answer are: 1.
- Trial name
- NIBSAAM (NCT06712849)
- Testing
- High Frequency Transcranial Random Noise Stimulation
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Midwestern University
Amblyopia, Anisometropic Ambyopia
Visual Cortex Stimulation in Patients With Amblyopia
This study will examine whether direct current (DC) polarization (electrical stimulation) of the visual cortex can cause a temporary improvement of vision in an amblyopic eye of an adult.
- Conditions
- Amblyopia, Anisometropic Ambyopia, Amblyopia, Suppression
- Trial name
- NCT00097162
- Testing
- Anodal stimulation
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- National Eye Institute (NEI)
Amblyopia
Augmenting Atropine Treatment for Amblyopia in Children 3 to < 8 Years Old
This study is designed to evaluate the effectiveness of adding a plano lens to weekend atropine after visual acuity has stabilized with weekend atropine but amblyopia is still present.
- Trial name
- ATS16 (NCT00944710)
- Testing
- Atropine, Plano lens
- Where
- 2 sites in United States
- Volunteers
- 73 people
- Sponsor
- Jaeb Center for Health Research