Clinical trials: Amblyopia, open to volunteers
Amblyopia
Interactive Binocular Treatment (I- BiT) in Adult Patients With Anisometropic Amblyopia
Amblyopia is one of the common, preventable and treatable causes of decreased acuity of one or both eyes without a specific organic cause.
- Trial name
- NCT07103473
- Testing
- Interactive Binocular Treatment
- Where
- Iran
- Volunteers
- 15 people
- Sponsor
- Shahid Beheshti University of Medical Sciences
Craniosynostosis, Strabismus
Ocular Characteristics in Patients With Craniosynostosis
Craniosynostosis are cranial deformations due to the premature closure of one or more cranial sutures. These deformations affect approximately one in 2.500 births.
- Conditions
- Craniosynostosis, Strabismus, Intracranial Hypertension, Amblyopia
- Trial name
- COPACA (NCT06928727)
- Where
- France
- Volunteers
- 65 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Amblyopia
Early Detection and Prevention of Amblyopia and Visual Impairment Through Systematic Pediatric Vision Screening
Amblyopia, characterized by reduced visual acuity, develops in childhood due to insufficient sensory stimulation of the affected eye.
- Trial name
- FALSSE (NCT07112560)
- Testing
- Standard screening procedure for amblyopia, New amblyopia screening method using a virtual reality headset.
- Where
- France
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University Hospital, Strasbourg, France
Amblyopia
Clinical Treatment of Transcranial Direct Current Stimulation in Older Adolescents With Amblyopia
As a neurodevelopmental visual disorder, amblyopia, especially monocular form-deprivation amblyopia, can lead to severe visual developmental impairments.
- Trial name
- NCT06760910
- Testing
- tDCS Stimulation, Anodal tDCS
- Where
- China
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Tianjin Eye Hospital
Amblyopia
Evaluation of AmblyoFix for the Treatment of Unilateral Amblyopia in Children
This is a prospective, single-arm, non-inferiority clinical trial designed to evaluate the efficacy, safety, and adherence of AmblyoFix binocular digital therapy for the treatment of unilateral amblyopia in children aged 7 to 12…
- Trial name
- NCT07323953
- Testing
- AmblyoFix binocular digital therapy
- Where
- Egypt
- Volunteers
- 33 people
- Sponsor
- Eyesight Electronics
Amblyopia
Video Treatment for Amblyopia
The purpose of this study is to determine whether viewing asynchronous movies leads to better visual outcomes in young children with amblyopia than standard-of-care occlusion therapy with an adhesive patch and whether this is…
- Trial name
- NCT05439200
- Testing
- Asynchronous 3D movies, Patching
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- Retina Foundation of the Southwest
Amblyopia
Dichoptic Treatment for Amblyopia in Children 4 to 7 Years of Age
In children 4 to 7 years of age, to determine if treatment with 1 hour per day 6 days per week of watching dichoptic movies/shows wearing the Luminopia headset is non-inferior to treatment with 2 hours of patching per day 7 days…
- Trial name
- ATS23 (NCT06380517)
- Testing
- Luminopia, Eye Patch
- Where
- 73 sites in United States
- Volunteers
- 238 people
- Sponsor
- Jaeb Center for Health Research
Amblyopia, Strabismus
Visual Function Abnormalities in Strabismus and Amblyopia and Response to Therapy
Amblyopia and strabismus are characterized by a reduction in visual acuity, contrast sensitivity, grating acuity, vernier acuity, reading difficulties and binocular visual function deficits.
- Trial name
- NCT04310241
- Testing
- Patching therapy, Glasses
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- The Cleveland Clinic
Amblyopia, Amblyopia Unilateral
Valproate for the Treatment of Residual Amblyopia
The goal of this clinical trial is to determine the efficacy of valproate as an adjunct therapy to treat amblyopia beyond the critical period in children aged 8-17 years who have amblyopia of ≥3 lines of interocular…
- Conditions
- Amblyopia, Amblyopia Unilateral, Amblyopia, Anisometropic, Amblyopia Strabismic
- Trial name
- VARA (NCT07226141)
- Testing
- Valproate, Patch
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- Boston Children's Hospital
Amblyopia, Anisometropic Amblyopia
Augmented Reality-Based Binocular Therapy for Visual Rehabilitation in Adults With Amblyopia
The goal of this clinical trial is to evaluate a home-based augmented reality-based binocular therapy designed to improve visual function in adults aged 18 to 40 years with unilateral anisometropic amblyopia, commonly called…
- Trial name
- Ambly4Home (NCT07819552)
- Testing
- Active Augmented Reality-Based Binocular Therapy
- Where
- 2 sites in Portugal
- Volunteers
- 60 people
- Sponsor
- Polytechnic Institute of Porto
Amblyopia
A Randomized Trial to Evaluate Sequential vs Simultaneous Patching
A randomized trial to determine whether simultaneous treatment with spectacles and patching has an equivalent VA outcome compared with sequential treatment, first with spectacles alone followed by patching (if needed), for…
- Trial name
- ATS22 (NCT04378790)
- Testing
- Patching, Glasses
- Where
- 68 sites in United States
- Volunteers
- 544 people
- Sponsor
- Jaeb Center for Health Research
Deprivation Amblyopia, Congenital Cataract
Augmented Reality Training for Amblyopia After Congenital Cataract Surgery
This study will evaluate whether augmented reality training is effective and safe for treating unilateral amblyopia after congenital cataract surgery in children.
- Trial name
- NCT07693790
- Testing
- Augmented Reality Amblyopia Training, Conventional Patching
- Volunteers
- 88 people
- Sponsor
- Zhongshan Ophthalmic Center, Sun Yat-sen University
Amblyopia, VEP
Possible Beneficial Effects Of Combined Fluoxetine And Occlusion Therapy In Improving And Maintaining Vision In Amblyopia Using Optical Coherence Tomography Angiography (OCTA) And Visual Evoked Potential (VEP). The Aim Of The Study Is To Evaluate Possible Beneficial Effects For Different Age Groups.
Amblyopia is described as a limitation of the visual function of one or both eyes with no pathological cause, with a prevalence of about 1-5% of the total world population.
- Trial name
- VA; OCTA; VEP; (NCT07417046)
- Testing
- Flouxetine, Patching therapy
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Minia University
Amblyopia, Strabismus
Attention-based Binocular Training for Impaired Stereopsis (BRAVE)
This study evaluates a novel attention-based binocular visual search training paradigm designed to improve stereopsis (stereo vision) in individuals with impaired binocular vision.
- Conditions
- Amblyopia, Strabismus, Anisometropia, Binocular Vision Abnormalities
- Trial name
- BRAVE (NCT07803458)
- Testing
- Attention-Guided Dichoptic Visual Search Training, Zero-Disparity Dichoptic Visual Search Task
- Where
- 2 sites in Hong Kong
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Centre for Eye and Vision Research
Amblyopia
Dichoptic Treatment for Amblyopia in Children 8 to 12 Years of Age
Participants eligible for the study will be randomly allocated (1:1:1) to receive either Luminopia dichoptic treatment while wearing optical correction if needed, Vivid Vision dichoptic treatment while wearing optical correction…
- Trial name
- ATS24 (NCT06524882)
- Testing
- Vivid Vision, Luminopia, Optical Correction
- Where
- 58 sites in United States
- Volunteers
- 252 people
- Sponsor
- Jaeb Center for Health Research
Amblyopia
OCT Eccentric Fixation and Amblyopia in Children
The objectives of this proposal are to characterize the relationship between OCT eccentric fixation (OCT-EF), fixation eye movement (FEM), macular sensitivity in children with amblyopia.
- Trial name
- NCT05714449
- Testing
- eye patch, After-image and MIT trainer
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- State University of New York College of Optometry
Amblyopia, Amblyopia Unilateral
Non-invasive Induction of Metaplasticity for Amblyopia
The goal of this clinical trial is to determine the efficacy of flicker therapy as an adjunct therapy to treat amblyopia beyond the critical period in adolescents and adults aged 14-40 years who have amblyopia of ≥3 lines of…
- Conditions
- Amblyopia, Amblyopia Unilateral, Amblyopia, Anisometropic, Amblyopia Strabismic
- Trial name
- NIMA (NCT07846397)
- Testing
- Flicker
- Volunteers
- 10 people
- Sponsor
- Boston Children's Hospital
Amblyopia, Visual Training
A Randomized Controlled Trial of Autostereoscopic 3D Vision Therapy for Amblyopia
The goal of this clinical trial is to learn if an autostereoscopic 3D amblyopia training system works to improve vision in children and adolescents with amblyopia.
- Conditions
- Amblyopia, Visual Training, Visual Functions, Visual Health
- Trial name
- NCT07709832
- Testing
- Autostereoscopic 3D Training, Conventional Patching
- Where
- China
- Volunteers
- 34 people
- Sponsor
- Beijing Tongren Hospital
Amblyopia
Noninvasive Brain Stimulation in Adult Amblyopia
The goal of this randomized controlled trial is to investigate the effectiveness of non-invasive brain stimulation in treating adults with amblyopia. The main questions it aims to answer are: 1.
- Trial name
- NIBSAAM (NCT06712849)
- Testing
- High Frequency Transcranial Random Noise Stimulation
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Midwestern University
Amblyopia
Optical Correction and Visual Functions of Adults With Amblyopia
Amblyopia is a developmental anomaly resulting from abnormal visual experiences in early life. Amblyopia causes reduced visual acuity in the absence of a pathology.
- Trial name
- SPECTRA (NCT05394987)
- Testing
- Spectacles
- Where
- 2 sites in Canada, Hong Kong
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Centre for Eye and Vision Research