Clinical trials: Amblyopia, active
Amblyopia
Dichoptic Treatment for Amblyopia in Children 4 to 7 Years of Age
In children 4 to 7 years of age, to determine if treatment with 1 hour per day 6 days per week of watching dichoptic movies/shows wearing the Luminopia headset is non-inferior to treatment with 2 hours of patching per day 7 days…
- Trial name
- ATS23 (NCT06380517)
- Testing
- Luminopia, Eye Patch
- Where
- 73 sites in United States
- Volunteers
- 238 people
- Sponsor
- Jaeb Center for Health Research
Deprivation Amblyopia, Congenital Cataract
Augmented Reality Training for Amblyopia After Congenital Cataract Surgery
This study will evaluate whether augmented reality training is effective and safe for treating unilateral amblyopia after congenital cataract surgery in children.
- Trial name
- NCT07693790
- Testing
- Augmented Reality Amblyopia Training, Conventional Patching
- Volunteers
- 88 people
- Sponsor
- Zhongshan Ophthalmic Center, Sun Yat-sen University
Amblyopia
Early Detection and Prevention of Amblyopia and Visual Impairment Through Systematic Pediatric Vision Screening
Amblyopia, characterized by reduced visual acuity, develops in childhood due to insufficient sensory stimulation of the affected eye.
- Trial name
- FALSSE (NCT07112560)
- Testing
- Standard screening procedure for amblyopia, New amblyopia screening method using a virtual reality headset.
- Where
- France
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University Hospital, Strasbourg, France
Amblyopia, VEP
Possible Beneficial Effects Of Combined Fluoxetine And Occlusion Therapy In Improving And Maintaining Vision In Amblyopia Using Optical Coherence Tomography Angiography (OCTA) And Visual Evoked Potential (VEP). The Aim Of The Study Is To Evaluate Possible Beneficial Effects For Different Age Groups.
Amblyopia is described as a limitation of the visual function of one or both eyes with no pathological cause, with a prevalence of about 1-5% of the total world population.
- Trial name
- VA; OCTA; VEP; (NCT07417046)
- Testing
- Flouxetine, Patching therapy
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Minia University
Amblyopia
Psilocybin for Amblyopia - Targeting Critical Periods in Humans
The purpose of this study is to evaluate whether ingestion of a drug called psilocybin can increase the effectiveness of amblyopia therapy in adults with amblyopia.
- Trial name
- PATCH (NCT07920081)
- Testing
- Amblyopia Therapy, 1 mg Psilocybin, 5 mg Psilocybin
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Johns Hopkins University
Amblyopia, Amblyopia Unilateral
Valproate for the Treatment of Residual Amblyopia
The goal of this clinical trial is to determine the efficacy of valproate as an adjunct therapy to treat amblyopia beyond the critical period in children aged 8-17 years who have amblyopia of ≥3 lines of interocular…
- Conditions
- Amblyopia, Amblyopia Unilateral, Amblyopia, Anisometropic, Amblyopia Strabismic
- Trial name
- VARA (NCT07226141)
- Testing
- Valproate, Patch
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- Boston Children's Hospital
Amblyopia, Amblyopia Unilateral
Non-invasive Induction of Metaplasticity for Amblyopia
The goal of this clinical trial is to determine the efficacy of flicker therapy as an adjunct therapy to treat amblyopia beyond the critical period in adolescents and adults aged 14-40 years who have amblyopia of ≥3 lines of…
- Conditions
- Amblyopia, Amblyopia Unilateral, Amblyopia, Anisometropic, Amblyopia Strabismic
- Trial name
- NIMA (NCT07846397)
- Testing
- Flicker
- Volunteers
- 10 people
- Sponsor
- Boston Children's Hospital
Amblyopia
Clinical Treatment of Transcranial Direct Current Stimulation in Older Adolescents With Amblyopia
As a neurodevelopmental visual disorder, amblyopia, especially monocular form-deprivation amblyopia, can lead to severe visual developmental impairments.
- Trial name
- NCT06760910
- Testing
- tDCS Stimulation, Anodal tDCS
- Where
- China
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Tianjin Eye Hospital
Amblyopia
Effect of Transcranial Magnetic Stimulation on Visual Functions of Adult Amblyopia: a Preliminary Study
Amblyopia, with a prevalence rates of 3% in adult population, is a common cause of vision impairment. It is characterized by impaired vision in one or both eyes because of disruption of normal visual stimuli and underdevelopment…
- Trial name
- NCT05393739
- Testing
- Theta burst transcranial magnetic stimulation (TBS) procedure
- Where
- Taiwan
- Volunteers
- 30 people
- Sponsor
- National Taiwan University Hospital
Amblyopia, Amblyopia Strabismic
Effectiveness of tDCS in Paediatric Amblyopia.
The goal of this randomized, double-blind clinical trial is to determine whether transcranial direct current stimulation (tDCS) can effectively and safely improve vision in children aged 4-14 years with strabismic or…
- Conditions
- Amblyopia, Amblyopia Strabismic, Visual Acuity, Stereoscopic Vision
- Trial name
- tDCS (NCT07547670)
- Testing
- tDCS
- Where
- Spain
- Volunteers
- 100 people
- Sponsor
- Universidad de Murcia
Refractory Amblyopia
Evaluation of Echothiophate in Pediatric Patients With Refractory Amblyopia
The goal of this clinical trial is to see if a medicine called echothiophate iodide (Phospholine Iodide) can help treat children with refractory amblyopia.
- Trial name
- NCT07554131
- Testing
- Echothiophate Iodide 0.125% Ophthalmic Solution
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Oklahoma
Amblyopia
Binocular Amblyopia Treatment
To evaluate the effectiveness of enhanced binocular amblyopia treatments in achieving a more complete and stable recovery.
- Trial name
- NCT03288948
- Testing
- Binocular games for treatment of amblyopia
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Retina Foundation of the Southwest
Amblyopia
Dichoptic Treatment for Amblyopia in Children 8 to 12 Years of Age
Participants eligible for the study will be randomly allocated (1:1:1) to receive either Luminopia dichoptic treatment while wearing optical correction if needed, Vivid Vision dichoptic treatment while wearing optical correction…
- Trial name
- ATS24 (NCT06524882)
- Testing
- Vivid Vision, Luminopia, Optical Correction
- Where
- 58 sites in United States
- Volunteers
- 252 people
- Sponsor
- Jaeb Center for Health Research
Congenital Cataract, Pediatric Cataract
Five-Year Visual Function and Refractive Outcomes After Congenital Cataract Surgery
This prospective multicenter observational study aims to evaluate the 5-year visual function and refractive outcomes in children undergoing surgery for congenital cataract.
- Trial name
- NCT07070037
- Where
- China
- Volunteers
- 400 people
- Sponsor
- Jin Yang
Amblyopia
Noninvasive Brain Stimulation in Adult Amblyopia
The goal of this randomized controlled trial is to investigate the effectiveness of non-invasive brain stimulation in treating adults with amblyopia. The main questions it aims to answer are: 1.
- Trial name
- NIBSAAM (NCT06712849)
- Testing
- High Frequency Transcranial Random Noise Stimulation
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Midwestern University
Amblyopia
Binocular Visual Therapy and Video Games for Amblyopia Treatment.
Amblyopia, or lazy eye, is best defined by the American Academy of Ophthalmology as a unilateral or bilateral reduction of the best corrected visual acuity that occurs in the setting of an otherwise normal eye, or a structural…
- Trial name
- NCT03655912
- Testing
- Red/green glasses, Electronic Tablet, Eye patch
- Where
- Mexico
- Volunteers
- 60 people
- Sponsor
- Universidad Autonoma de Nuevo Leon
Amblyopia
Patch-free Occlusion Therapy
The purpose of the study is to determine whether a patch-free occlusion therapy leads to better visual outcomes in young children with amblyopia than standard-of-care occlusion therapy with an adhesive patch and whether this is…
- Trial name
- NCT05440448
- Testing
- Patch-free occlusion therapy, Adhesive patch
- Where
- United States
- Volunteers
- 68 people
- Sponsor
- Retina Foundation of the Southwest
Amblyopia, Anisometropic Amblyopia
Combining Noninvasive Brain Stimulation and Augmented Reality-based Dichoptic Therapy for Treating Amblyopic Adults
The goal of this clinical trial is to learn whether adding noninvasive brain stimulation to augmented reality-based vision therapy can improve vision in adults aged 18 to 40 years with unilateral anisometropic amblyopia, commonly…
- Trial name
- NiBS4Vision (NCT07752433)
- Testing
- Active High-Definition Transcranial Direct Current Stimulation, Augmented Reality-Based Dichoptic Therapy
- Where
- 2 sites in Portugal
- Volunteers
- 80 people
- Sponsor
- Polytechnic Institute of Porto
Amblyopia
A Study on the Efficacy and User Experience of Gamified Intervention for Children With Anisometropic Amblyopia
This project addresses the challenge of visual function intervention in children with monocular anisometropic amblyopia. It employs two innovatively designed digital games combined with occlusion therapy to conduct visual…
- Trial name
- NCT07472231
- Testing
- Serious touchscreen game combined with occlusion, Augmented reality game combined with occlusion, Occlusion therapy
- Where
- China
- Volunteers
- 66 people
- Sponsor
- Xinhua Hospital, Shanghai Jiao Tong University School of Medicine
Amblyopia
Comparison of Binocular Spectacle Prescription Versus Patching Therapy in Refractive Amblyopia Patients
This study will examine on Refractive Amblyopia patients, whose amblyopia started due to longstanding uncorrected refractive errors.
- Trial name
- NCT06739798
- Testing
- Exp Group, Control Group
- Where
- Pakistan
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Superior University