Clinical trials: Ambulances
Acute Myocardial Infarction
GPIIbIIIa Inhibitors in the RESCUe and RESURCOR Networks at the Acute Myocardial Infarction
In patients with acute myocardial infarction who are managed in the prehospital setting, and who will treated with primary angioplasty, we evaluate the benefit of an early administration of tirofiban, a powerful GPIIbIIIa…
- Trial name
- AGIR2 (NCT00538317)
- Testing
- tirofiban
- Where
- France
- Volunteers
- 320 people
- Sponsor
- Hospices Civils de Lyon
Parkinson's Disease
SEDPARK1: Safety and Efficacy Study With the Non-ergot Dopamine-agonist Piribedil in Parkinson's Disease
The aim of the non-interventional Post Marketing Study is to investigate the use of the non-ergot dopamine agonist piribedil (trade name: CLARIUM) in mono- and combination therapy in patients with Morbus Parkinson.
- Trial name
- PIR-001/K (NCT00725478)
- Testing
- Piribedil
- Volunteers
- 250 people
- Sponsor
- Desitin Arzneimittel GmbH
Traffic Accidents
The Impact of Prehospital Trauma Life Support (PHTLS) on Outcome of Traffic Injury
Trauma is the leading cause of death among persons below 60 years of age. It is a well-established belief that optimal treatment in the early phase after trauma has a major impact on mortality, and the implementation of specific…
- Trial name
- NCT01603537
- Where
- Sweden
- Volunteers
- 40,000 people
- Sponsor
- Uppsala University Hospital
Stroke, Acute Ischemic
Potential Use of a POCT for the Direct Transfer of Stroke Patients From the Ambulance to the Thrombectomy Center
Stroke is the leading cause of long-term disability and the second most common cause of death worldwide. Currently, the protocols require the imaging techniques at the hospitals to differ ischemic strokes with large vessel…
- Trial name
- NCT05833945
- Testing
- Large Vessel Occlusion Biomarkers Test
- Where
- 16 sites in Spain
- Volunteers
- 355 people
- Sponsor
- Fundación Pública Andaluza para la gestión de la Investigación en Sevilla
Aged, Home Care, Hospital-Based
Home-based Acute Care for Older Persons Initiated by the Emergency Medical and Ambulance Services - a Retrospective Observation of Effects on Healthcare Utilisation and Mortality
This observational study aims to examine outcomes of home-based acute care delivered by a mobile healthcare team in persons aged 75 years and older following an episode of acute illness.
- Conditions
- Aged, Home Care, Hospital-Based, Home Care Services, Emergency Medical Dispatch Centre
- Trial name
- NCT07472335
- Testing
- Type of care pathway
- Where
- Sweden
- Volunteers
- 5,000 people
- Sponsor
- Vastra Gotaland Region
Stroke
Telestroke Triage in Suspected Stroke Patients
The ASTRAL trial is a randomized study in patients with suspected stroke in the ambulance setting. The study evaluates whether prehospital telestroke consultation, in addition to standard care, can reduce unnecessary stroke code…
- Trial name
- ASTRAL (NCT07657117)
- Testing
- Telestroke triage, Standard Care (in control arm)
- Where
- Netherlands
- Volunteers
- 518 people
- Sponsor
- Nyika D. Kruyt
Suspected Stroke
Early Initiated Ambulance-delivered Levetiracetam and Headposition in Hyper-acute Stroke Trial
This is an investigator initiated and conducted, multicentre, ambulance-delivered, prospective, randomised, open-label, blinded outcome (PROBE) study.
- Trial name
- EAST (NCT06773364)
- Testing
- Levetiracetam, Guide-recommended management, The lying flat (0°) head position
- Where
- 2 sites in China
- Volunteers
- 2,423 people
- Sponsor
- Shanghai East Hospital
Telemedicine, Disaster Medicine
Feasibility of Telemedicine Under Ambulance Station Conditions
Our aim is to evaluate the feasibility of telemedicine in context of medical service in an ambulance station and in a further step in context of civil defense situations.
- Conditions
- Telemedicine, Disaster Medicine, Emergency Medicine
- Trial name
- NCT05388071
- Testing
- Usage of telemedicine and tele-consultation for treatment
- Where
- Germany
- Volunteers
- 404 people, healthy volunteers welcome
- Sponsor
- RWTH Aachen University
Endotracheal Intubation
Augmented Reality Smart Glasses Versus Video Laryngoscopy During Ambulance Transport
This randomized crossover simulation study evaluated the performance of augmented reality (AR) smart glasses compared with conventional video laryngoscopy (VL) for endotracheal intubation under simulated prehospital ambulance…
- Trial name
- AR-AMBULANCE (NCT07865663)
- Testing
- Augmented Reality-Assisted Laryngoscopy, Video Laryngoscopy
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- ONUR KARAKAYALI
Emergency Patients Being Transported by Rescue Ambulance
Data Acquisition for Connected Network for EMSs Comprehensive Technical-support Using Artificial Intelligence
Currently, the domestic emergency medical system is disconnected from the information flow between hospitals, emergency sites, and control agencies, which are participants in the emergency medical system, and there are…
- Trial name
- NCT05939258
- Where
- South Korea
- Volunteers
- 15,296 people, healthy volunteers welcome
- Sponsor
- Yonsei University
Body Core Temperature, Thermal Comfort
Active Warming in Prehospital Trauma Care
Prevention and treatment of hypothermia by active warming in prehospital trauma care is recommended but scientifical evidence of its effectiveness in a clinical setting is scarce.
- Trial name
- NCT01400152
- Testing
- Additional active warming
- Where
- Sweden
- Volunteers
- 48 people
- Sponsor
- Umeå University
Blood Pressure, Work-Related Condition
Physical Actitvity and Blood Pressure Among Ambulance Personnel During Work and Leisure
The aim is to describe physical activity and blood pressure during work and leisure time among Swedish ambulance personnel, and to relate this to work- and lifestyle factors.
- Trial name
- NCT05020977
- Testing
- Blood pressure, physical activity, health
- Where
- Sweden
- Volunteers
- 64 people
- Sponsor
- Jonkoping University
Stroke, Acute, Pre-hospital Triage
Stroke Triage Optimization by Ambulance Paramedics in the Pre-hospital Setting
There are everal scales designed to help ambulance paramedics to identify a patient with a stroke and activate a stroke code. These scales were never tested in the field in a large unselected patient sample.
- Conditions
- Stroke, Acute, Pre-hospital Triage, Stroke Treatment, Stroke Code
- Trial name
- STROKE-APP (NCT06332989)
- Testing
- stroke-APP
- Where
- Netherlands
- Volunteers
- 3,000 people
- Sponsor
- Leiden University Medical Center
Emergency Medical Services, Nursing Care
High-Sensitivity Troponin I in Addition to Guideline-Based Care in EMS
The TIGER study is a study investigating the utlility of a point-of-care blood analyse of Troponin I to help identify patients with heart attacks in the prehospital emergency care.
- Conditions
- Emergency Medical Services, Nursing Care, Cardiology, Myocardial Infarction
- Trial name
- TIGER (NCT07008391)
- Testing
- high sensitivity Troponin I
- Where
- Sweden
- Volunteers
- 1,419 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Alcohol Use, Unspecified, Substance Use
Ambulance Calls for Substance Use and Alcohol in a Pandemic (ASAP)
The Primary objective is to explore ambulance service attendance at incidents involving alcohol and/or substance use over the period of the pandemic lockdown, and the following months.
- Conditions
- Alcohol Use, Unspecified, Substance Use, Intoxication Alcohol, Emergencies
- Trial name
- ASAP (NCT04474444)
- Testing
- attendance by ambulance crew
- Where
- United Kingdom
- Volunteers
- 55,000 people, healthy volunteers welcome
- Sponsor
- University of Lincoln
Cardiac Arrest
Laryngeal Tube vs Laryngeal Mask Airway
Introduction: The laryngeal mask airway (LMA) is used as the primary airway by paramedics in Singapore Civil Defense Force's Emergency Ambulance Service (SCDF's EAS) in the management of out-of-hospital cardiac arrest, because…
- Trial name
- NCT02607644
- Testing
- Laryngeal Mask Airway (LMA), Laryngeal Tube (LT)
- Where
- Singapore
- Volunteers
- 965 people
- Sponsor
- Singapore General Hospital
Wounds and Injuries, Accidents, Occupational
Work Related Injuries Among Prehospital Emergency Medical Staff, an Observational Study
Ambulance personnel often work in a dangerous environment and work related injuries of emergency medical staff have repeatedly been documented.
- Trial name
- NCT01091610
- Testing
- no intervention
- Where
- 2 sites in Switzerland
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Out-of-hospital Cardiac Arrest
CPR Quality Between Flexible Stretcher and Standard Stretcher in OHCA
This study aims to compare the quality of emergency medical services cardiopulmonary resuscitation between flexible stretcher and standard stretcher during ambulance transport to hospital among out-of-hospital cardiac arrest…
- Trial name
- ASIA-CPR (NCT02527694)
- Testing
- Flexible EMS stretcher cart, mechanical CPR
- Where
- South Korea
- Volunteers
- 49 people
- Sponsor
- Seoul National University Hospital
COPD Exacerbation, Trauma
FreeO2 PreHospital - Automated Oxygen Titration vs Manual Titration According to the BLS-PCS
Evaluation of automated oxygen titration in comparison with manual adjustment oxygen in the out-of-hospital setting by paramedics.
- Trial name
- NCT03696563
- Testing
- Automated oxygen administration - FreeO2, Standard administration of oxygen flow
- Volunteers
- 100 people
- Sponsor
- François Lellouche
Respiratory Distress Syndrome
Prehospital Telemedicine Feasibility/Acceptability Pilot
Teleconsultation, or the use of video telecommunications technology to deliver expert recommendations for care remotely, has been used to improve the safety and quality of emergency care for children in hospital-based acute care…
- Trial name
- NCT05967624
- Testing
- Teleconsultation
- Where
- 2 sites in United States
- Volunteers
- 20 people
- Sponsor
- Boston Medical Center