Clinical trials: Ambulation Disorder, Neurologic
Opioid Use Disorder, Chronic Pain
An Adaptive Walking Intervention to Manage Chronic Pain in Veterans With Opioid Use Disorder Engaged in Opioid Agonist Treatment
Severe chronic pain and opioid use disorder (OUD) occur at significantly higher rates in Veterans compared to the general population.
- Trial name
- NCT05051644
- Testing
- Steps 2 Change (S2C), Control
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- VA Office of Research and Development
Multiple Sclerosis
Observational Study for Assessment of the Effect of Fampyra on the Manual Function of Persons With Multiple Sclerosis
Multiple Sclerosis (MS) is the most common chronic neurological disease affecting young adults, with onset usually at age 20-40 years. Women are affected 3-4 times more than men.
- Trial name
- NCT01547234
- Where
- Israel
- Volunteers
- 47 people
- Sponsor
- Carmel Medical Center
Spinal Cord Injuries
Effects of Ambulation Training Utilizing an Exoskeleton Robot on Subjects With Spinal Cord Injury
The present study aims to investigate the effects of ReWalk exoskeleton robot training on various physiological and psychological parameters among subjects with spinal cord injury, including body composition and bone mineral…
- Trial name
- NCT03340792
- Testing
- Ambulation training utilizing an exoskeleton robot
- Where
- Taiwan
- Volunteers
- 10 people
- Sponsor
- China Medical University Hospital
Amputation, Phantom Limb Pain
Prosthesis With Sensations
Lower limb amputees suffer complete lack of sensory feedback of current available prostheses, which excludes the central nervous system from the correct sensory-motor integration.
- Conditions
- Amputation, Phantom Limb Pain, Sensory Deficit
- Trial name
- NCT03350061
- Testing
- SENSY
- Where
- Serbia
- Volunteers
- 3 people
- Sponsor
- Clinical Centre of Serbia
Multiple Sclerosis
Clinical Investigation of the Quality of Life Benefit of Using a Home Walking Exoskeleton for a Population of Multiple Sclerosis Patients.
The goal of this clinical investigation is to evaluate the effectiveness of home use of a lightweight robotic lower limb exoskeleton as a walking aid device on quality of life in patients with multiple sclerosis with gait…
- Trial name
- EXHOMESEP (NCT05835622)
- Testing
- Keeogo, adviced home practice
- Where
- 6 sites in France
- Volunteers
- 28 people
- Sponsor
- Pôle Saint Hélier
Spinal Cord Injuries, Multiple Sclerosis
Functional and Physiological Responses to Lokomat Therapy (Pilot Study)
Individuals with neurological deficiencies such as those who have spinal cord injury, stroke, traumatic brain injury, Parkinson's disease, and multiple sclerosis often lose their ability to ambulate over ground.
- Conditions
- Spinal Cord Injuries, Multiple Sclerosis, Stroke
- Trial name
- NCT00883142
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- US Department of Veterans Affairs
Healthy, Spastic Hemiparesis
Soleus Loading Response During Walking
Stroke survivors experience motor deficits, weak voluntary muscle activations, and low weight-bearing capacity that impair ambulation.
- Conditions
- Healthy, Spastic Hemiparesis, Stroke
- Trial name
- NCT05436366
- Testing
- Soleus loading response in able-bodied participants, Soleus loading response in participants with hemiparesis
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Victor H. Duenas
TBI (Traumatic Brain Injury), Brain Concussion
Dual-Task Exercise for Mild Traumatic Brain Injury (mTBI)
The investigators previously developed a virtual 14-day dual-task walking exercise program and tested its feasibility with individuals with mild traumatic brain injury (mTBI) history.
- Conditions
- TBI (Traumatic Brain Injury), Brain Concussion, Clinical Trial, Rehabilitation
- Trial name
- NCT06037603
- Testing
- Brain & Walk Exercise Every Day (BraW-Day)
- Where
- United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- University of Nevada, Las Vegas
Multiple Sclerosis
Yoga in Multiple Sclerosis Patients
Objective The objective of this study will be to compare the effects of an eight-week Yin-based yoga program and conventional physiotherapy on fatigue, balance, gait, and quality of life in individuals with Multiple Sclerosis…
- Trial name
- NCT07155642
- Testing
- yoga, conventional physiotheraphy
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people
- Sponsor
- Istanbul Rumeli University
Foot Drop
Innovative Shoe for People With Foot Drop
People with foot drop have an increased risk of tripping and falling, and this makes walking more difficult. Our colleagues at the Health Design Collective (HDC) have developed a shoe that aims to make it easier for people with…
- Trial name
- NCT06911151
- Testing
- innovative footwear
- Where
- United Kingdom
- Volunteers
- 15 people
- Sponsor
- Queen Margaret University
Healthy, Psychological Distress
The Effects of the Somatic Intervention 'Dance-Walk' on Body Awareness, Vitality, and Mental Health in Help-Seeking Adults: a RCT Study
The goal of this clinical trial is to learn if a movement program called "Dance-Walk" can improve body awareness, energy levels, and mental health in adults seeking mental health support.
- Conditions
- Healthy, Psychological Distress, Stress, Depression Disorders
- Trial name
- DANCEWALK (NCT07024901)
- Testing
- Dance-walk
- Where
- Lithuania
- Volunteers
- 117 people, healthy volunteers welcome
- Sponsor
- Vilnius University
Stroke, Healthy
Walking With the EksoNR in Stroke Patients and Healthy Controls: Biomechanical Changes and User Experience.
Further studies are needed to provide more detailed information on the potential effects of robotic gait training in general, as well as on the influence on gait movement patterns in particular.
- Trial name
- NCT05334030
- Testing
- High Swing Assistance, Neutral Swing Assistance, High Swing Resistance
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Vrije Universiteit Brussel
Multiple Sclerosis
Open-Label Extension Study to Evaluate the Safety, Tolerability and Activity of Oral Fampridine-SR in Patients With Multiple Sclerosis Who Participated in the MS-F204 Trial
The purpose of the study is to evaluate the safety, tolerability and activity of Fampridine-SR when administered for up to 36 additional months in patients who previously participated in the MS-F204 study or until it becomes…
- Trial name
- NCT00649792
- Testing
- Fampridine-SR
- Where
- 42 sites in United States, Canada
- Volunteers
- 214 people
- Sponsor
- Acorda Therapeutics
Multiple Sclerosis
Neuromuscular Electrical Stimulation and Mobility in Multiple Sclerosis
The purpose of this study is to investigate the capacity of a 6-week treatment with neuromuscular electrical stimulation to improve walking in individuals whose mobility has been compromised by multiple sclerosis.
- Trial name
- NCT02152085
- Testing
- Narrow pulse, Wide pulse
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- University of Colorado, Boulder
Multiple Sclerosis, Walking, Difficulty
3 Meter Backwards Walk Test and Multiple Sclerosis
Multiple Sclerosis (MS) is an autoimmune, demyelinating disease of the central nervous system that causes different levels of disability with motor and sensory loss.
- Conditions
- Multiple Sclerosis, Walking, Difficulty, Balance; Distorted
- Trial name
- NCT04004026
- Testing
- Assesment
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Sanko University
Spinal Cord Injuries
Closed-loop Functional Spinal Cord Stimulation in Patients With Spinal Cord Injury
The purpose of this experiment is to evaluate the efficacy of Closed-loop Functional Spinal Cord Stimulation on Walking Rehabilitation in Patients after Spinal Cord Injury
- Trial name
- COFUN (NCT04969042)
- Testing
- Pins Medical G122 RS
- Where
- China
- Volunteers
- 10 people
- Sponsor
- Luming Li
Alzheimer's Dementia, Falls
Wii-Fit For Improving Activity, Gait And Balance In Alzheimer's Dementia
Alzheimer's Dementia (AD) contributes to poor balance, impaired gait and functional status, thereby, increasing the risk of falls. AD is an independent risk factor for hip fractures.
- Conditions
- Alzheimer's Dementia, Falls, Gait Impairment, Balance Impairment
- Trial name
- NCT01002586
- Testing
- Wii-Fit intervention, Walking exercise program
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- University of Nebraska
Multiple Sclerosis
Impact of Neuropsychological Disorders in Multiple Sclerosis
The study involves MS patients with and without neuropsychological disorders. The patient will benefit from: A routine neuropsychological assessment, including a cognitive and emotional assessment A clinical examination A…
- Trial name
- SEVISEP (NCT04837365)
- Testing
- Three dimensional gait analysis with eyetracking
- Where
- 3 sites in France
- Volunteers
- 32 people
- Sponsor
- Lille Catholic University
Spinal Cord Injuries, Spinal Injuries
DBS of PPN to Improve Walking in Chronic SCI Patients
Spinal cord injury (SCI) is a devastating condition affecting over 1 million individuals in North America. SCI often results in severe motor impairments with few available treatments options.
- Conditions
- Spinal Cord Injuries, Spinal Injuries, Spinal Fractures
- Trial name
- NCT04325165
- Testing
- DBS Implantation
- Sponsor
- University Health Network, Toronto
Bone Resorption
The Novel Unloading Device "HEPHAISTOS" and Its Effects Upon Bone, Muscle and Vasculature
The present study aimed to investigate the importance of gravitational induced forces that appear during normal ambulation for the health of muscles, bones and blood vessels.
- Trial name
- HEP (NCT01576081)
- Testing
- HEPHAISTOS
- Where
- Germany
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- DLR German Aerospace Center
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