Clinical trials: Ambulation Disorder, Neurologic
Cerebral Palsy, Gait Disorders
The Effects of Exoskeletal Robot-Assisted Gait Training on Children With Cerebral Palsy: A Pilot Study
Cerebral Palsy (CP) is a complex neurodevelopmental disorder caused by early brain injury, leading to motor impairments such as muscle weakness, stiffness, and gait instability, which impact daily functioning.
- Conditions
- Cerebral Palsy, Gait Disorders, Gait Disorders in Children, Gait Disorders, Neurologic
- Trial name
- NCT05759182
- Testing
- Powered Exoskeleton Gait Training
- Where
- South Korea
- Volunteers
- 10 people
- Sponsor
- COSMO ROBOTICS CO., Ltd
Multiple Sclerosis, Pilates Exercise
The Effect of Remotely Delivered Pilates on Physical , and Psychological Outcomes in Individuals With Multiple Sclerosis
Objectives Objective 1: To determine the effects of a 16-week remotely delivered Pilates intervention on walking endurance, walking speed, balance, fatigue, and pain compared to a waitlist control group in individuals with MS.
- Conditions
- Multiple Sclerosis, Pilates Exercise, Walking, Balance
- Trial name
- MS (NCT07504120)
- Testing
- Pilates
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Illinois Chicago
Acute Stroke, TIA (Transient Ischemic Attack)
Sms-guided Training After Acute Stroke or Transient Ischemic Attack - a Randomized Controlled Trial
Eighty community-living individuals in Uppsala municipality will be included. Intervention: Outdoor walking exercise program and one strength exercise. Methods: Clinical assessments, questionnaires and medical records.
- Trial name
- SMS/TIA (NCT02902367)
- Testing
- Outdoor walking and strength exercise, control group
- Where
- Sweden
- Volunteers
- 80 people
- Sponsor
- Uppsala County Council, Sweden
Spinal Cord Injury, Spinal Cord Injuries
Testosterone Plus Finasteride Treatment After Spinal Cord Injury
The purpose of this study is to determine whether testosterone plus finasteride treatment will improve musculoskeletal health, neuromuscular function, body composition, and metabolic health in hypogonadal men who have experienced…
- Conditions
- Spinal Cord Injury, Spinal Cord Injuries, Trauma, Nervous System, Wounds and Injuries
- Trial name
- NCT02248701
- Testing
- Testosterone Enanthate, Finasteride
- Where
- 2 sites in United States
- Volunteers
- 33 people
- Sponsor
- VA Office of Research and Development
Spinal Cord Injuries
Effects of Caffeine and Intermittent Hypoxia on Leg Function in Human Spinal Cord Injury
Accumulating evidence suggests that repeatedly breathing low oxygen levels for brief periods (termed intermittent hypoxia) is a safe and effective treatment strategy to promote meaningful functional recovery in persons with…
- Trial name
- NCT02323698
- Testing
- Caffeine, AIH
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Spaulding Rehabilitation Hospital
Paraplegia, Complete
Effect of the Atalante Exoskeleton on Standing and Walking in Individuals With Paraplegia: A Prospective Controlled-Environment Study in a Rehabilitation Context
This clinical study aims to evaluate the feasibility, safety, and acceptability of the Atalante robotic exoskeleton, developed by Wandercraft, within a functional rehabilitation protocol for individuals with complete paraplegia.
- Trial name
- APPEX (NCT06941896)
- Testing
- Use of the Atalante Exoskeleton
- Where
- France
- Volunteers
- 13 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Stroke
Constraint Induced Movement Therapy for Walking in Individuals Post Stroke
To compare the effect of constraint induced movement therapy (CIMT) vs. treadmill training only on walking function in individuals post-stroke, a 6 week, single-blind, randomized training study will be conducted with three…
- Trial name
- NCT03264261
- Testing
- robotic training, treadmill training
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- Shirley Ryan AbilityLab
Musculoskeletal Pain
A Proactive Walking Trial to Reduce Pain in Black Veterans
The long term goal is to improve the quality and equity of chronic pain treatment among VA patients. The primary objective of this study is to improve pain outcomes among black VA patients with chronic, musculoskeletal (MSK)…
- Trial name
- ACTION (NCT01983228)
- Testing
- Intervention Condition
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- VA Office of Research and Development
Gait Disorders, Neurologic, Stroke
Effect of Gait Training With a Walking Assist Robot on Gait Function and Balance in Patients With Chronic Stroke
The purpose of this study was to investigate the effects of gait training with the new wearable hip assist robot developed by Samsung Advance Institute of Technology (Samsung Electronics Co, Ltd, Korea) in patients with chronic…
- Trial name
- NCT03326011
- Testing
- Samsung Hip Assist v1
- Where
- South Korea
- Volunteers
- 7 people
- Sponsor
- Samsung Medical Center
Cerebral Palsy
Does Botulinum Toxin Injections Improve Outdoor Activity in Children With Cerebral Palsy?- a Pilot Study
Background: Motor impairment limits social and recreational activities in children with cerebral palsy (CP), compromising participation and impacting on quality of life.
- Trial name
- NCT01335100
- Where
- Israel
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Shaare Zedek Medical Center
Stroke, Post-stroke Hemiparesis
Operant Conditioning of Reflex Pathways to Improve Walking in Individuals Post-stroke
The purpose of this study is to examine the changes in reflex pathways in the paretic ankle plantarflexors in individuals with post-stroke hemiparesis using operant conditioning.
- Conditions
- Stroke, Post-stroke Hemiparesis, Foot Drop
- Trial name
- NCT05801744
- Testing
- Operant conditioning
- Where
- United States
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- University of Nevada, Las Vegas
Foot Drop, Peripheral Nervous System Diseases
Walking Ankle Robot for Foot Drop in Aging and Disabled Populations: A Demonstration Project
The purpose of this research study is to test the utility of an ankle robot, when used during treadmill walking, in people with ankle weakness and foot drop from a peripheral nervous system injury due to neuromuscular or…
- Conditions
- Foot Drop, Peripheral Nervous System Diseases, Gait Disorders, Neurologic, Mobility Limitation
- Trial name
- NCT03556709
- Testing
- Treadmill Ankle Robot Training
- Volunteers
- 100 people
- Sponsor
- Baltimore VA Medical Center
Spinal Cord Injuries
Lokomat® vs RoboGait® Under Different Guidance Force Settings in Motor-Incomplete SCI
This study compares two robotic-assisted gait training systems, Lokomat® and RoboGait®, used under different guidance force (GF) settings, in people with motor-incomplete spinal cord injury (iSCI).
- Trial name
- NCT07137780
- Testing
- Lokomat® V6 (GF < 90%), Lokomat® V6 (GF ≥ 90%), RoboGait®
- Where
- Turkey (Türkiye)
- Volunteers
- 19 people
- Sponsor
- Ankara City Hospital Bilkent
Spinal Cord Injuries, Paraplegia
Evaluation of Safety and Performance of the Atalante System With Patients With Lower Limb Paralysis
The study is a prospective, open, bicentric and observational study. It is conducted to assess the safety and performance of the Atalante exoskeleton system with patients with lower limb paralysis.
- Conditions
- Spinal Cord Injuries, Paraplegia, Paralysis, Lower Limbs, Lower Extremity
- Trial name
- NCT04110561
- Testing
- Use of the Atalante exoskeleton
- Where
- 2 sites in France
- Volunteers
- 12 people
- Sponsor
- Wandercraft
Stroke
Effects Of Task-Oriented Training In Individuals With Stroke
The purpose of this study is to investigate the effects of task-oriented training on balance,functional mobility,walking, activities of daily living and quality of life in individuals with stroke.
- Trial name
- NCT05671211
- Testing
- Task-Oriented Training, Conventional Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 28 people
- Sponsor
- Ege University
Prostatic Hyperplasia
The Effect of Using a Motivation Card on Pain and Number of Walking Steps After Prostate Surgery
The purpose of this clinical study is to evaluate the effect of using motivational cards on pain and step counts in patients who underwent open prostate surgery due to benign prostatic hyperplasia.The main hypotheses are: H1…
- Trial name
- NCT06699563
- Testing
- Mobilization Motivation Card
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Trakya University
Cerebral Palsy, Spastic
Altered Back Geometry and Mobility Function After Backward Walking Training in Children With Cerebral Palsy
PURPOSE: To assess the effect of backward walking training on back geometry and mobility function in children with hemiparetic cerebral palsy through a comparative analysis with forward walking training.
- Trial name
- NCT04981964
- Testing
- Exercise training
- Where
- Egypt
- Volunteers
- 33 people
- Sponsor
- Cairo University
Neurologic Gait Disorder
Myosuit-based Gait Training
This study will investigate the safety and feasibility of over-ground training sessions with the Myosuit for the neurological inpatients of rehabilitation clinic Zihlschlacht with a gait disorder and their therapists.
- Trial name
- NCT05485597
- Testing
- Myosuit-based gait training
- Where
- Switzerland
- Volunteers
- 15 people
- Sponsor
- Rehaklinik Zihlschlacht AG
Stroke, Healthy
The Effect of a Walking Assist Robot on Gait Function and Brain Activity in Stroke Patients and Elderly Adults
The purpose of this study was to investigate the effects of the new wearable hip assist robot, gait enhancing and motivating system (GEMS) developed by Samsung Advanced Institute of Technology (Samsung Electronics Co, Ltd.…
- Trial name
- NCT03048968
- Testing
- Gait, sit-to-stand movement, stair climbing and treadmill gait, Sit-to-stand movement and treadmill gait, gait enhancing mechatronic system (GEMS)
- Where
- South Korea
- Volunteers
- 40 people
- Sponsor
- Samsung Medical Center
Cerebral Palsy
PlayGait: A Dynamic Exoskeleton
PlayGait is an investigational dynamic energy storage and return (ESR) lower-limb exoskeleton for young children with cerebral palsy (CP), that stores energy while the child is in the stance phase of walking and returns that…
- Trial name
- NCT05318690
- Testing
- PlayGait, Baseline
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Orthocare Innovations, LLC
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