Clinical trials: Ambulation Disorder, Neurologic
Severe Stroke or Similar Neurological Muscle Weakness
Mobility Training Using Exoskeletons for Functional Recovery After Stroke
The purpose of this study is to assess the safety and effectiveness of the Ekso robotic exoskeleton in persons affected by a severe stroke.
- Trial name
- NCT02128152
- Testing
- Ekso exoskeleton
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Shirley Ryan AbilityLab
Injuries, Spinal Cord
Sit-to-stand in Spinal Cord Injury Patient
1. Were there differences in functional ability between ambulatory individuals with SCI who passed and failed the independent sit-to-stand (iSTS) task? 2.
- Trial name
- NCT02916784
- Volunteers
- 69 people
- Sponsor
- Khon Kaen University
Healthy, Stroke
Error-augmented Walking on Gait Performance and Brain Activities in Stroke
This three-year study is proposed to document the effect and further implementation of error-augmented walking on gait performance and brain activities in individuals with stroke.
- Trial name
- NCT04455334
- Testing
- Error-augmented treadmill training, active control group, Error-augmented concept combined physical therapy group
- Where
- Taiwan
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Stroke, Gait Disorders, Neurologic
Robot Walking Rehabilitation in Stroke Patients
Stroke are the main causes of motor disability among adults and are expected to impose an increasing social and economic burden for our Country.
- Trial name
- RoboSTROKE (NCT01678547)
- Testing
- Robot-assisted walking, Treadmill Training, Ground treatment
- Where
- 2 sites in Italy
- Volunteers
- 28 people
- Sponsor
- IRCCS San Raffaele Roma
Blindness
Continued Study of Artificial Vision: Evaluation of the BrainPort® System and Investigation of Visual Ambulation
The purpose of this study is to evaluate the use of an artificial vision system called Brainport system in blind patients To investigate visual, and oculomotor (eye motion) mechanisms involved in the use of the Brainport system.
- Trial name
- BrainPort (NCT02643238)
- Testing
- BrainPort
- Where
- United States
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- Akron Children's Hospital
Spinal Cord Injuries
Walking Rehabilitation After Spinal Cord Injury: Locomotor Training Using Adaptive Robotics
Locomotor training is an established rehabilitation approach that is beneficial for improving walking function in individuals with spinal cord injuries (SCIs).
- Trial name
- NCT03504826
- Testing
- Hybrid Assistive Limb (HAL)
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- Brooks Rehabilitation
Spinal Cord Injuries, Inpatient
Exoskeletal-Assisted Walking in SCI Acute Inpatient Rehabilitation
The purpose of this research study is to test the effect of early exoskeletal-assisted walking (EAW) training (combined into regular acute inpatient rehabilitation (AIR)) on improving functional recovery and reducing pain and…
- Trial name
- NCT04221373
- Testing
- Ekso™ powered exoskeleton, Standard of care
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Spinal Muscular Atrophy
Mechanisms and Treatment of Exercise Intolerance and Persistent Fatigue in Spinal Muscular Atrophy
This study will focus on the pathophysiological underpinnings of reduced exercise capacity and fatigue in ambulatory patients with spinal muscular atrophy (SMA).
- Trial name
- NCT05518773
- Testing
- Observational
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- Columbia University
Stroke Patients
The Relationship of Bone Mineral Density With Balance, Functional Ambulation and Falls in Stroke Patients
The aim of this study is to investigate the relationship between bone mineral density and balance, functional ambulation and falls in hemiparetic patients with stroke in the subacute and chronic phases.
- Trial name
- NCT05207748
- Testing
- Bone mineral density
- Where
- Turkey (Türkiye)
- Volunteers
- 44 people
- Sponsor
- Gaziler Physical Medicine and Rehabilitation Education and Research Hospital
Cerebral Palsy
Effect of Nordic Walking on Gait-asymmetry Patterns in Children With Hemiparesis
Nordic walking is a physical activity consisting of walking with poles similar to ski poles. The poles are designed for the purpose of activating the upper body during walking.
- Trial name
- NCT05644652
- Testing
- designed physical therapy program, Nordic walking
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Cairo University
Spinal Muscular Atrophy Type 2
GCB-001 in Treatment of Patients With Type II (SMA) Spinal Muscular Atrophy
This study explored dose escalation of single-arm, open, single intrathecal injection in patients with delayed onset type 2 SMA. The investigator plans to conduct 2 cohorts.
- Trial name
- GITOPWTSMA (NCT06772402)
- Testing
- GCB-001
- Where
- China
- Volunteers
- 6 people
- Sponsor
- Genecombio Ltd.
Fibromyalgia
Evaluation of Adherence of Women With Fibromyalgia to Walking Prescriptions
Although there are many studies evaluating adherence to supervised walking programs in patients with fibromyalgia (FM), there are limited studies evaluating adherence to unsupervised walking programs.
- Trial name
- NCT05996692
- Testing
- Evaluation of adherence to walking prescriptions
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Gaziler Physical Medicine and Rehabilitation Education and Research Hospital
Stroke, Chronic Stroke
Reflex Excitability in Post-stroke Stiff-Knee Gait
The purpose of this study is to examine the reflex excitability of the rectus femoris in individuals with and without post-stroke Stiff-Knee gait.
- Conditions
- Stroke, Chronic Stroke, Gait, Hemiplegic, Gait, Spastic
- Trial name
- NCT04947865
- Testing
- Peripheral nerve stimulation, Commercial knee brace
- Where
- United States
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- MetroHealth Medical Center
Stroke, Inpatients
A Novel Approach to Enhance True Recovery After Stroke
The purpose of this study is to elucidate pathophysiological mechanisms behind gait disturbances during the early recovery phase after hemiparetic stroke to identify targets for new treatment strategies.
- Conditions
- Stroke, Inpatients, Recovery of Function, Observational Study
- Trial name
- NCT05359367
- Testing
- Observational
- Where
- Sweden
- Volunteers
- 6 people
- Sponsor
- Danderyd Hospital
Incomplete Spinal Cord Injury, Transverse Myelitis
Ultrasound Imaging Based Sensing of Human Ankle Motion Intent and Control Strategies for Ankle Assistance
Robotic therapies aim to improve limb function in individuals with neurological injury. Modulation of robotic assistance in many of these therapies is achieved by measuring the extant volitional strength of limb muscles.
- Trial name
- NCT05249595
- Testing
- Surface electromypgraphy-based interface to predict human ankle joint motion intent and use in ankle assistive devices, Ultrasound imaging-based interface to predict human ankle joint motion intent and use in ankle assistive devices, Surface electromypgraphy and ultrasound imaging-based interface to predict human ankle joint motion intent and use in ankle assistive devices
- Where
- 2 sites in United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- North Carolina State University
Parkinson Disease
Robotic Walking Device to Improve Mobility in Parkinson's Disease
This Phase II randomized controlled trial proposes to examine the impact of long-term use of a novel light-weight and wearable assistive robotic device, called the Honda Walking Assist (HWA) device, to improve mobility in the…
- Trial name
- NCT03751371
- Testing
- Training with HWA device, Usual Care
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Ohio State University
At Risk for AD-dementia, With Subjective Cognitive Decline, At Risk for Cognitive Decline
High-Velocity Resistance Training for Brain Blood Flow and Cognitive Function in Older Adults
The goal of this clinical trial is to learn whether a 12-week high-velocity resistance training program can improve brain blood flow and thinking skills in adults ages 60 to 79 who are at higher risk for Alzheimer's disease and…
- Trial name
- NCT07444554
- Testing
- High-Velocity Resistance Training
- Volunteers
- 60 people
- Sponsor
- University of Illinois Chicago
Stroke
Electrophysiological and Clinical Effects of Walking Downhill in Stroke Patients
investigation of the effects of walking for 20 minutes on the acute H/M ratio on flat ground, downhill slopes at -7.5 degrees and -15 degrees in patients who have had a stroke, have spasticity and are ambulatory.
- Trial name
- NCT05833295
- Testing
- Downhill walking, Walking on flat ground
- Where
- Turkey (Türkiye)
- Volunteers
- 21 people
- Sponsor
- Marmara University
Parkinson Disease
Changes in Metabolic Activity, and Gait Function by Dual-task Cognitive Game-based Treadmill Intervention in Parkinson's Disease.
The present proposal will evaluate the neural underpinnings of (a) the decline of mobility function in Parkinson's disease (PD), and (b) the effects of an innovative computer-guided dual-task (DT) mobility training platform…
- Trial name
- CMAGDT (NCT04415775)
- Testing
- Game based treadmill Program, Conventional Gait Rehabilitation
- Where
- Canada
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Stroke
Reliability and Validity of The Figure of 8 Walk Test With and Without Dual-Task
For people with stroke, walking on a curved path is more difficult than walking on a straight path and can lead to falls. Most of the outcome scales assessing the gait of people with stroke involve walking in a straight line or…
- Trial name
- NCT06540482
- Testing
- Reliability test
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people
- Sponsor
- Afyonkarahisar Health Sciences University
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