Clinical trials: Ambulation Disorder, Neurologic
Spinal Cord Injuries (SCI), Paraplegia and Tetraplegia
Self-balancing Personal Exoskeleton for SCI
This study aims to demonstrate the safety and effectiveness of the Eve personal exoskeleton in individuals with spinal cord injury (SCI).
- Trial name
- NCT06777576
- Testing
- Hands-free exoskeleton
- Where
- 2 sites in United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Wandercraft
Walking, Cognitive Function
Transcranial and Rapid Magnetic Stimulation for Gait Apraxia Due to Normal Pressure Hydrocephalus and Cerebral Ischemia
The investigator(neurologist) has published a study in International Congress Series, in the 15th International Conference of Biomagnetism Vancouver Proceedings 2006,and Science Direct website, of 15 patients with brain ischemia…
- Trial name
- NCT00494689
- Where
- 2 sites in Singapore
- Volunteers
- 30 people
- Sponsor
- Devathasan Neurology Practice Pte Ltd
Knee Osteoarthritis
Efficacy of Celecoxib vs Placebo to Prevent Pain in a Paced Walk
A paced 20-minute walk is a reproducible model for acute pain in knee osteoarthritis
- Trial name
- NCT00194090
- Testing
- celecoxib
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University Hospitals Cleveland Medical Center
Accidental Falls, Gait Disorders
Virtual Reality for Walking and Balance in Older Adults
Falls are common in older adults due to aging-related problems with walking (gait) and balance. Virtual Reality (VR) is a new technology that creates interactive video game-like exercises.
- Conditions
- Accidental Falls, Gait Disorders, Neurologic Injury
- Trial name
- VR-GAIT (NCT07655882)
- Testing
- Virtual Reality Headset, Conventional Gait and Balance Training
- Where
- Pakistan
- Volunteers
- 36 people
- Sponsor
- University of Faisalabad
Parkinson Disease, Healthy Aging
ParKinWalk: Physical Activity and Long Group-walking for Parkinson's Disease
The study will evaluate the impact of exercise training program followed by long-walking onon supervised and unsupervised gait assessment in Parkinson´s disease and control subjects.
- Trial name
- ParKInWalk (NCT04266782)
- Testing
- Exercise program followed by long walk in group, Exercise program followed by long walk in group (controls)
- Where
- Italy
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Università degli Studi di Brescia
Brain Fog, Cognitive Impairment
Cognitive Task-Based Walking Effects on Cognition, Mood, Sleep, and Quality of Life in Older Adults With Brain Fog
This randomized controlled trial aims to investigate the effects of cognitive task-based walking exercise on cognitive function, depressive symptoms, sleep quality, and quality of life in older adults experiencing brain fog.
- Conditions
- Brain Fog, Cognitive Impairment, Geriatric Population
- Trial name
- NCT07396779
- Testing
- Cognitive Task-Based Walking Exercise, Walking-Only Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Medipol University
Ambulation Difficulty, Gait, Unsteady
The Sensorimotor Locus of Balance Control in Elderly Gait
The aging population is at an exceptionally high risk of debilitating falls, contributing significantly to reduced independence and quality of life.
- Conditions
- Ambulation Difficulty, Gait, Unsteady, Fall, Position Sense Disorders
- Trial name
- NCT03341728
- Testing
- Optical flow perturbations, Normal walking
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Stroke
Step Test and Six Minute Walk Test in Stroke
The purpose of this study is to investigate the viability of using the Step Test (ST) in stroke patients, and to compare the functional performance of the physiologic variables in stroke patients during ST and Six Minute Walk…
- Trial name
- NCT01436630
- Testing
- Step Test and Six Minute Walk.
- Where
- Brazil
- Volunteers
- 12 people
- Sponsor
- Faculdades Metropolitanas Unidas
Multiple Sclerosis
VR and Orthoses for Rehabilitation in Multiple Sclerosis
This non-drug, non-medical device, interventional study explores the feasibility of integrating virtual reality (VR) with wearable sensors to support gait training using a passive orthosis in individuals with multiple sclerosis…
- Trial name
- VIRTUE (NCT07096700)
- Testing
- VR and walking brace-based gait rehabilitation
- Where
- 2 sites in Italy
- Volunteers
- 12 people
- Sponsor
- Azienda Usl di Bologna
Stroke
Exoskeleton for Balance
Many people who have experienced a stroke have deficits in their walking balance. The long-term goal of this research is to develop an exoskeleton that can effectively improve walking balance, thus improving functional mobility.
- Trial name
- NCT07356011
- Testing
- No Exoskeleton, Exoskeleton (zero impedance), Exoskeleton (low impedance)
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- Medical University of South Carolina
Stroke
Prospective Cohort Study : Evaluation of Prognosis Criteria for Walking Independently Recovery After Stroke.
Based on a 2017 US study that developed an algorithm for predicting independent walking recovery after stroke, we propose a prospective study to assess the validity and applicability of this algorithm in the majority of stroke…
- Trial name
- NCT05572892
- Testing
- FAC scale
- Where
- France
- Volunteers
- 72 people
- Sponsor
- University Hospital, Caen
Muscle Cramp, Hemodialysis
The Effect of Home-Based Walking on Symptoms and Health Profile of Hemodialysis Patients
This study aims to evaluate the effect of 8 weeks of home-based moderate-speed walking on hemodialysis symptoms and health profile while patients are receiving hemodialysis treatment.
- Conditions
- Muscle Cramp, Hemodialysis, Vibration, Stretching
- Trial name
- NCT07272070
- Testing
- Group A (Home-based walking), Group B (Usual hemodialysis care )
- Where
- Turkey (Türkiye)
- Volunteers
- 24 people
- Sponsor
- Figen Akay
Spinal Cord Injuries, Paraplegia, Spinal
Activity-Dependent Transspinal Stimulation in SCI
Robotic gait training is often used with the aim to improve walking ability in individuals with Spinal Cord Injury. However, robotic gait training alone may not be sufficient.
- Conditions
- Spinal Cord Injuries, Paraplegia, Spinal, Tetraplegia/Tetraparesis, Paraplegia, Spastic
- Trial name
- NCT03669302
- Testing
- Robotic gait training, Robotic gait training and low-frequency transspinal stimulation, Robotic gait training and high-frequency transspinal stimulation
- Where
- 2 sites in United States
- Volunteers
- 10 people
- Sponsor
- City University of New York
Spinal Cord Injuries
Clinical Investigation on the Impact on Safety, Feasibility and Usability of the Design Changes Performed on ABLE Exoskeleton Device With Spinal Cord Injured Patients in a Hospital Setting
The loss of the ability to walk and the associated restriction of mobility presents a major challenge to people with spinal cord injury in an everyday environment designed for pedestrians.
- Trial name
- NCT05590065
- Testing
- ABLE Exoskeleton
- Where
- Spain
- Volunteers
- 5 people
- Sponsor
- ABLE Human Motion S.L.
Stroke
Effects of Voluntary Adjustments During Walking in Participants Post-stroke
People post-stroke retain the capacity to modify walking patterns explicitly using biofeedback and implicitly when encountering changes in the walking environment.
- Trial name
- NCT06034119
- Testing
- Split belt treadmill, Biofeedback
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Chapman University
Dementia
Enhancing Mobility and Mental Health in Dementia Patients
This study aims to evaluate the effect of a multidisciplinary six-minute walking group and activities on patients with dementia\'s physical activity levels, mobility, anxiety, and cognitive function.
- Trial name
- NCT06611202
- Testing
- Exercise, Clonazepam
- Where
- United Kingdom
- Volunteers
- 6 people
- Sponsor
- Oxleas NHS Foundation Trust
Parkinson Disease, Gait Disorders, Neurologic
Benefits of Different Exercise Types to Enhance Walking for PD
Background: Gait disturbance is one of the most common complaints from patients with Parkinson's disease (PD). It is well-established that people with PD have motor learning impairments.
- Trial name
- NCT04895787
- Testing
- Gait + aerobic exercise, Gait + resistance exercises, Gait + conventional physical therapy
- Where
- Taiwan
- Volunteers
- 70 people
- Sponsor
- National Taiwan University Hospital
Cerebrovascular Accident
Oxygen Consumption in Post-stroke Patients During Various Walking Activities Compared to Healthy Controls
Stroke is major public health issue. The investigators recommend post-stroke patients to practice physical activity. Nevertheless, the recommendations are not widely respected due to the intensity of exercises.
- Trial name
- STROXCO (NCT05477238)
- Testing
- walking tasks
- Where
- France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University Hospital, Limoges
Cerebral Palsy
Pilot Study on the Validity, Tolerability, and Impact of a Walking Rehabilitation Intervention Using Cruro-Malleolar Cast in Children With Cerebral Palsy
This pilot study investigates whether walking training using cruro-malleolar casts (CMCs) - rigid leg splints extending from the thigh to the ankle - can safely improve gait quality in children with bilateral cerebral palsy (CP).
- Trial name
- RCMs (NCT07650370)
- Testing
- Cruro-Malleolar Cast Walking Training
- Volunteers
- 6 people
- Sponsor
- Centre Médico-Chirurgical de Réadaptation des Massues Croix Rouge Française
Multiple Sclerosis
Pelvic Proprioceptive Neuromuscular Facilitation (PNF) Exercises in Multiple Sclerosis Patients
Multiple Sclerosis (MS) is an autoimmune, demyelinating disease that progresses with motor and sensory loss of the central nervous system and causes disability at different levels.
- Trial name
- NCT06198972
- Testing
- Pelvic Pnf exercises, Strength exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Kahramanmaras Sutcu Imam University
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