Clinical trials: Ambulation Disorder, Neurologic
Charcot-Marie-Tooth Disease, Type IA, Peripheral Neuropathy Hereditary
Physical Activity Level at Home in CMT1A Patients: Wearable Sensor Assessment
Charcot-Marie-Tooth disease type 1A (CMT1A) is the most common hereditary peripheral neuropathy, affecting approximately 26,000 patients in France.
- Conditions
- Charcot-Marie-Tooth Disease, Type IA, Peripheral Neuropathy Hereditary, Motor Activity, Walking, Difficulty
- Trial name
- CMT1A-HOME (NCT07591779)
- Where
- France
- Volunteers
- 60 people
- Sponsor
- University Hospital, Limoges
Spastic Cerebral Palsy
Effects of Functional Progressive Strength Training in Children With Spastic Cerebral Palsy
This study focuses on the effects of Functional Progressive Strength Training (FPST) on children with spastic cerebral palsy, a condition characterized by increased muscle tone that affects movement.
- Trial name
- NCT06407869
- Testing
- Functional Progressive Strength Training, Control
- Where
- Pakistan
- Volunteers
- 40 people
- Sponsor
- Riphah International University
Stroke
Brain Activity Changes After Structured Cognitive-motor Exercise for People With Stroke
To assess the effects of a dual-task exercise program on cognitive-motor interference during dual-task walking and the associated changes in brain activity.
- Trial name
- NCT06129227
- Testing
- Dual-task training, Single-task training, Control group
- Where
- Hong Kong
- Volunteers
- 108 people
- Sponsor
- The Hong Kong Polytechnic University
Multiple Sclerosis, Cerebral Lesion
Auditory-motor Coupling in Multiple Sclerosis With Cerebellar Lesions
This study is a case-control observational study, involving persons with multiple sclerosis and healthy controls. The study contains 1 descriptive and 4 experimental sessions.
- Trial name
- NCT04639401
- Testing
- motor entrainment to auditory cues and music during walking on quality of movement
- Where
- 2 sites in Belgium
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Hasselt University
Multiple Sclerosis
Functions, Physical Activity and Employment for Individuals With MS: A Pilot Feasibility Study
Multiple Sclerosis (MS) is a chronic disease affecting young adults. Impaired balance, walking, reduced physical activity and participation in employment are common, however, less integrated in the health care.
- Trial name
- CoreDISTp (NCT05057338)
- Testing
- CoreDISTparticipation, Standard care
- Where
- 2 sites in Norway
- Volunteers
- 30 people
- Sponsor
- Nordlandssykehuset HF
Stroke
The Effect of Backward Walking Treadmill Training on Balance in Patient With Chronic Stroke
The purpose of this research was to discuss the effect of backward walking treadmill training on balance ability, speed of walking and cardiopulmonary fitness in patients with chronic stroke.
- Trial name
- NCT02619110
- Testing
- backward walking treadmill training, conventional physical therapy
- Where
- Taiwan
- Volunteers
- 30 people
- Sponsor
- Kaohsiung Medical University Chung-Ho Memorial Hospital
Stroke, Hemiplegic Gait
The Effects of Plantar Flexion Training in People With Chronic Stroke
This study consists of three phases that aim to develop an exercise intervention to promote maximal activation of ankle plantar flexors in the paretic lower extrimty (LE) in order to restore a more normalized gait pattern in…
- Trial name
- NCT03548090
- Testing
- Skateboard exercise at an incline angle of 0 degrees and 50% body weight, Skateboard exercise at an incline angle of 5 degrees and 50% body weight, Skateboard exercise at an incline angle determined to be optimal in phase 1 (either 0 or 5 degrees) and 75% body weight
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- The University of Texas Health Science Center, Houston
Stroke, Knowledge, Attitudes, Practice
Effects of an Educational Intervention on Rehabilitation Clinicians' Practices for Health-related Outcomes After Stroke
The overall aim of this pilot study is to evaluate the feasibility of a study protocol for a future stepped wedge cluster randomized clinical trial (c-RCT) that will investigate the effects of an innovative KT intervention on 1)…
- Conditions
- Stroke, Knowledge, Attitudes, Practice, Physical Disability, Motor Skills Disorders
- Trial name
- NCT03807115
- Testing
- Implementation of stroke mobility guidelines
- Where
- 6 sites in Canada
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- McGill University
Duchenne Muscular Dystrophy
Safety and Efficacy Study of IGF-1 in Duchenne Muscular Dystrophy
The purpose of this study is to determine whether IGF-1 therapy improves or preserves muscle function in Duchenne Muscular Dystrophy (DMD).
- Trial name
- NCT01207908
- Testing
- IGF-1
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Parkinson Disease
Walking and mHealth to Increase Participation in Parkinson Disease
Identifying effective ways to improve function, slow decline and reduce disability is a high priority for people living with Parkinson disease and other chronic conditions.
- Trial name
- WHIPPD (NCT03517371)
- Testing
- mHealth delivered exercise program, Exercise only
- Where
- 2 sites in United States
- Volunteers
- 140 people
- Sponsor
- Boston University Charles River Campus
Multiple Sclerosis
Exercise With and Without Cognitive Training
This proposal aims to conduct a 10-week randomized controlled trial comparing walking and resistance training with and without computerized cognitive training in older Veterans with Multiple Sclerosis, followed by 12 months of…
- Trial name
- NCT07447115
- Testing
- Effect of Exercise with and Without Cognitive Training on Gait
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- VA Office of Research and Development
Stroke
Effects of Rhythmic Auditory Cueing Augments Cognitive Treadmill Walking Training in Individuals With Chronic Stroke
The first objective of this study is to examine the superiority of the combined rhythmic auditory cueing with cognitive treadmill training (combined group) in people with stroke as compared with the cognitive treadmill walking…
- Trial name
- NCT06392945
- Testing
- Cognitive Treadmill Walking Training with Rhythmic Auditory Cueing (CTW+RAC) group, Cognitive Treadmill Walking Training (CTW) group, Treadmill Walking Training (TW)
- Where
- Taiwan
- Volunteers
- 90 people
- Sponsor
- Chang Gung University
Parkinson Disease, Gait Disorders, Neurologic
Optimal Verbal Instruction to Improve Walking for PD
Background: One of the most disturbing motor symptoms in Parkinson's disease (PD) is gait disturbance. Clinicians often use various verbal instructions to correct abnormal gait patterns, and the most commonly used instruction is…
- Trial name
- NCT04315285
- Testing
- Treadmill gait training with verbal instruction
- Where
- Taiwan
- Volunteers
- 35 people
- Sponsor
- National Taiwan University Hospital
Systemic Lupus Erythematosus
The Effectiveness of Walking in Patients With Systemic Lupus Erythematosus
Expected Results: Finding from this evidence-based study ought to clarify the effectiveness of walking intervention for patients with SLE, and provide reference for future nursing strategies to improve disease adaptability.
- Trial name
- NCT04983784
- Testing
- walking, Routine care
- Where
- Taiwan
- Volunteers
- 100 people
- Sponsor
- Dalin Tzu Chi General Hospital
Lumbar Spinal Stenosis, Lumbar Spondylolisthesis
Effectiveness and Safety of Korean Medicine for Low Back Pain or Sciatica Due to Lumbar Stenosis/Spondylolisthesis
A prospective observational study investigating the effectiveness and safety of integrative Korean medicine treatment in lumbar stenosis or spondylolisthesis patients with low back pain or sciatica at 3 locations of Jaseng…
- Conditions
- Lumbar Spinal Stenosis, Lumbar Spondylolisthesis, Low Back Pain, Sciatica
- Trial name
- NCT03879447
- Testing
- Herbal medicine, Chuna manual medicine, Bee venom pharmacopuncture
- Where
- South Korea
- Volunteers
- 110 people
- Sponsor
- Jaseng Medical Foundation
Multiple Sclerosis
Assistive Device Training in Multiple Sclerosis
The purpose of this study is to determine whether a training program in the use of ambulatory assistive devices (such as canes, walkers, etc) can reduce falls and increase functional mobility and neural connectivity in people…
- Trial name
- ADT (NCT02408718)
- Testing
- Assistive Device Training
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Portland VA Medical Center
Fatigue, Walking, Difficulty
Neurophysiological Effects of Transcutaneous Electrical Nerve Stimulation in Persons With MS
Transcutaneous Electrical Nerve Stimulation (TENS) is a treatment that could potentially reduce walking problems and fatigue in persons with Multiple Sclerosis.
- Conditions
- Fatigue, Walking, Difficulty, Multiple Sclerosis
- Trial name
- NCT06432686
- Testing
- Transcutaneous Electrical Nerve Stimulation, Movement
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University Medical Center Groningen
Pain, Osteoarthritis
Adductor Canal Block With Posterior Capsular Injection for Total Knee Replacement
To compare early ambulation and ability to participate in rehabilitation in patients undergoing total knee replacement using two different nerve block techniques for pain control.
- Trial name
- NCT01805661
- Testing
- Canal Block and Capsular Injection, Femoral with Tibial Nerve Block
- Where
- United States
- Volunteers
- 56 people
- Sponsor
- Trinity Health Of New England
Spinal Muscular Atrophy Type 3, Duchenne Muscular Dystrophy (DMD)
Establishing Walking-related Digital Biomarkers in Rare Childhood Onset Progressive Neuromuscular Disorders
The purpose of this research is (1) to identify disease specific walking-related digital biomarkers of disease severity, and (2) monitor longitudinal changes in natural environments, for extended periods of time, in DMD and SMA.
- Trial name
- NCT06839469
- Where
- 3 sites in United States
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- Columbia University
Fibromyalgia Syndrome
A Study Comparing Real and Sham Repetitive Transcranial Magnetic Stimulation in Adults With Fibromyalgia, Assessing Effects on Pain, Fatigue, Sleep, Mood, Quality of Life, Cognition, and Walking Under Usual and Dual-task Conditions
Fibromyalgia is a chronic condition that causes widespread pain and is often accompanied by fatigue, poor sleep, mood symptoms, memory and concentration difficulties, and reduced quality of life.
- Trial name
- FMS-TMS-GAIT (NCT07685379)
- Testing
- Active repetitive transcranial magnetic stimulation
- Where
- Serbia
- Volunteers
- 30 people
- Sponsor
- Institute of Rheumatology, Serbia
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