Clinical trials: Ambulation Disorder, Neurologic
Cerebral Stroke, Hemiplegia
Treadmill Therapy and Brain Injuries
Introduction. There is a demand for evidence whether treadmill therapy is more efficient than traditional walking training as an intervention for patients with hemiplegia after cerebral stroke. Design.
- Conditions
- Cerebral Stroke, Hemiplegia, Moderate to Severe Functional Impairments
- Trial name
- NCT01000168
- Testing
- Treadmill therapy and conventional walking therapy.
- Where
- Norway
- Volunteers
- 60 people
- Sponsor
- Sunnaas Rehabilitation Hospital
Stroke
Interactive Exoskeleton Robot for Walking
A new lower-limb training system is introduced to enhance the clinical service for post-stroke lower limb rehabilitation and to assist the establishment of public clinical trial in different settings and share experiences on the…
- Trial name
- NCT03184259
- Testing
- Robotic ankle system, Robotic knee system
- Where
- Hong Kong
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Cerebral Palsy
Gait Training Program With Blood Flow Restriction in Children With Cerebral Palsy - EMBRIN: Pilot Study
This is a single-center prospective experimental pilot study to assess the feasibility, tolerability and effect of a 10-week gait training program combined with simultaneous blood flow restriction (BFR) on the walking speed of…
- Trial name
- EMBRIN (NCT06533956)
- Testing
- 10-week gait training program combined with simultaneous blood flow restriction (BFR).
- Where
- 2 sites in France
- Volunteers
- 13 people
- Sponsor
- University Hospital, Angers
Lower Limb Injury, Stroke
Assistive Hip Exoskeleton Study for Stroke
The increased metabolic and biomechanical demands of ambulation limit community mobility in persons with lower limb disability due to neurological damage.
- Trial name
- NCT03924765
- Testing
- Powered hip exoskeleton
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Georgia Institute of Technology
Multiple Sclerosis
Wearable Lower Extremity Exoskeleton to Promote Walking in Persons With Multiple Sclerosis
The purpose of this study is to investigate whether a wearable robotic exoskeleton can help people with multiple sclerosis (MS) to walk again.
- Trial name
- NCT02519244
- Testing
- Ekso® (Wearable lower limb exoskeleton)
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- The University of Texas Health Science Center, Houston
Hearing Impaired Children
Retro Walking With and Without Bosu Ball for Balance and Mobility in Hearing Impaired Children
his randomized controlled trial aims to evaluate the effects of retro walking with and without BOSU ball training on balance and mobility in hearing-impaired children aged 8-12 years.
- Trial name
- NCT07578909
- Testing
- Retro walking, Bosu Ball
- Where
- Pakistan
- Volunteers
- 24 people
- Sponsor
- Riphah International University
Severe Obesity
Adherence to Walking on an Alter G Anti-Gravity Treadmill
Several barriers to exercise are present that need to be addressed. Morbidly obese individuals experience more skin friction, urinary stress incontinence, knee pain, low back pain, and hip arthritis than the lean population…
- Trial name
- NCT03690752
- Testing
- unweighting using Alter-G Anti-Gravity Treadmill, normal weight using Alter-G Anti-Gravity Treadmill
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Texas Tech University
Parkinson Disease
Assessment of Transcranial Electrical Stimulation and Auditory Stimulation During Walking in Parkinson Patients
Parkinson's disease affects 1 in 100 people over the age of 60. Parkinson's disease (PD) is a progressive disease of the nervous system that affects movement, produced by the destruction of dopaminergic neurons found in a region…
- Trial name
- NCT05264909
- Testing
- Multi-channel Transcranial direct current stimulation
- Where
- Chile
- Volunteers
- 5 people
- Sponsor
- Corporación de Rehabilitación Club de Leones Cruz del Sur
Stroke
Locomotor Experience Applied Post Stroke Trial
The purpose of this study is to compare two different treatments to improve walking after stroke (or post-stroke).
- Trial name
- LEAPS (NCT00243919)
- Testing
- Early locomotor training program, Late locomotor training program, Home Exercise Program
- Where
- 8 sites in United States
- Volunteers
- 408 people
- Sponsor
- Duke University
Reliability and Validity
The 3-Meter Backward Walk Test in Individuals With Multiple Sclerosis
The 3-m backward walk test (3MBWT) is used to evaluate neuromuscular control, proprioception, protective reflexes, fall risk and balance.
- Trial name
- NCT04753411
- Volunteers
- 50 people
- Sponsor
- Firat University
Multiple Sclerosis (MS) - Relapsing-remitting
Effects of Ublituximab on Motor Functions in Multiple Sclerosis
The purpose of this study is to test if ublituximab changes walking functions and fall risk in people with relapsing multiple sclerosis (RMS). Twenty-five qualified people with RMS will undergo a 48-week ublituximab treatment.
- Trial name
- U-PACE (NCT06629428)
- Testing
- Ublituximab
- Where
- 2 sites in United States
- Volunteers
- 25 people
- Sponsor
- Georgia State University
Parkinson Disease
PaDAWAn: Parkinson's Disease - Adaptive Walking Assistance
The goal of this study is to develop and validate a haptic assistive method in order to support walking in patients with Parkinson's disease, delivered to the patient's hips through a wearable robotic pelvis orthosis.
- Trial name
- PaDAWAn (NCT04314973)
- Testing
- Active Pelvis Orthosis, Walking exercises
- Where
- Belgium
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Université Catholique de Louvain
Multiple Sclerosis
Feasibility and Acceptability of Orthotic Shorts for People With Multiple Sclerosis
Walking can be slow and unsteady in people with multiple sclerosis (MS). This study will investigate whether orthotic shorts might help.
- Trial name
- NCT03164031
- Testing
- Close-fitting orthotic shorts, Looser fitting shorts
- Where
- United Kingdom
- Volunteers
- 16 people
- Sponsor
- Sheffield Hallam University
Stroke, Chronic Stroke
Optimizing Training in Severe Post-Stroke Walking Impairment
Difficulty walking is common after a stroke. Although physical rehabilitation helps a little with the improvement of walking ability, recovery is usually incomplete.
- Conditions
- Stroke, Chronic Stroke, Walking, Difficulty, Gait, Hemiplegic
- Trial name
- BLT2b (NCT04721860)
- Testing
- Backward Locomotion Treadmill Training (BLTT), Forward Locomotion Treadmill Training (FLTT)
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- University of Cincinnati
Brain Ischemia, Stroke, Ischemic
Effectiveness of a Neuromuscular Exercise Program and Visual Feedback in the Management of Body Position for Stroke Survivors
The aim of the biomedical research is to evaluate the changes of body position management during standing and walking for stroke patients, using innovative training methods during the rehabilitation.
- Trial name
- NCT05187559
- Testing
- Standard physiotherapy, Biodex Balance SD and Biodex Gait Trainer
- Where
- Lithuania
- Volunteers
- 120 people
- Sponsor
- Lithuanian University of Health Sciences
Multiple Sclerosis
Walking Fatigability,Saptiotemporal Gait Parameters and Falling in MS Patients
This observational study aims to investigate the relationship between walking fatigability, changes in spatiotemporal gait parameters, and risk of falling in individuals with multiple sclerosis (MS).
- Trial name
- WF-GAIT-FALL (NCT07524556)
- Where
- Egypt
- Volunteers
- 62 people
- Sponsor
- Ibrahim Ahmad Elmongy
CP (Cerebral Palsy)
Tolerance of a Motorized Orthosis Reproducing Walking Movement vs Conventional Standing-up Devices in Child With CP
Cerebral palsy (CP) includes all the sensorimotor development disorders leading to balance, gait and movement disruptions. These disorders are related to lesions of the central nervous system (CNS) that occurs at birth or during…
- Trial name
- EOMEC/CP (NCT02669160)
- Testing
- PC Innowalk, Conventional passive stander
- Where
- 4 sites in France
- Volunteers
- 25 people
- Sponsor
- Lille Catholic University
Stroke
Tracking Balance and Walking Recovery After Stroke
This study aims to understand how balance and walking abilities recover after a stroke, using innovative tools like an interactive assessment game.
- Trial name
- FOSTER (NCT06806761)
- Testing
- Longitudinal prospective cohort study
- Where
- Belgium
- Volunteers
- 100 people
- Sponsor
- Vrije Universiteit Brussel
Cerebral Palsy
BeFAST or BeSTRONG: Brain Change After Fun Athletic Sports-skill Training or Brain Change After Strength TRaining Focusing ON Gait
The purpose of this study is to compare a motor learning (ML)-based gait-related training intervention to a functional lower limb strength training intervention, with a concurrent evaluation of functional, neural and…
- Trial name
- NCT02754128
- Testing
- BeFAST, BeSTRONG
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- Holland Bloorview Kids Rehabilitation Hospital
Multiple Sclerosis, Foot Drop
Walking With FES or AFO in People With MS With Foot Drop
This investigation consists of two parallel groups of participants who will follow the same protocol. The aim of the study is to investigate the effects of using Functional Electrical Stimulation/Ankle Foot Orthosis (AFO) or…
- Trial name
- NCT01977287
- Testing
- Functional Electrical Stimulation, Ankle Foot Orthosis
- Where
- United Kingdom
- Volunteers
- 18 people
- Sponsor
- Queen Margaret University
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