Clinical trials: Ambulation Disorder, Neurologic
Acute Stroke, Stroke, Ischemic
Measuring Ambulation, Motor, and Behavioral Outcomes With Post-Stroke Fluoxetine in Tanzania
This is a phase II, randomized study of 120 adults age 18 or above who will prescribed 20mg daily Fluoxetine for 90 days following acute, ischemic stroke.
- Trial name
- MAMBO (NCT03728153)
- Testing
- Fluoxetine 20 MG Oral Tablet
- Where
- Tanzania
- Volunteers
- 34 people
- Sponsor
- Massachusetts General Hospital
Stroke, Ambulation Difficulty
Effect of Functional Electric Stimulation for Recovery of Dorsiflexion After Stroke
The purpose of this project is to investigate the effect of functional electrical stimulation (FES) for recovery of dorsiflexion after stroke.
- Conditions
- Stroke, Ambulation Difficulty, Hemiplegia
- Trial name
- NCT04945395
- Testing
- FES and Conventional training, AFO and Conventional training
- Where
- Sweden
- Volunteers
- 20 people
- Sponsor
- Danderyd Hospital
Stroke, Biomarkers
Relationship Between Serum Markers and Motor Recovery and Ambulation in Post-stroke Patients
This study aim to retrospectively investigate the effects of the magnesium, vitamin D, and uric acid serum markers on motor recovery and ambulation in post-stroke patients.
- Conditions
- Stroke, Biomarkers, Serum Magnesium, Serum Vitamin D
- Trial name
- NCT07086092
- Testing
- Serum magnesium, uric acid, and vitamin D levels and motor recovery and ambulation stages
- Where
- Turkey (Türkiye)
- Volunteers
- 257 people
- Sponsor
- Abant Izzet Baysal University
Stroke
Effects of Combined Treatment by Botulinum Toxin and Lokomat® on Walking Ability in Chronic Stroke
75% patients in the chronic phase of a stroke keep walking disabilities. Focal spasticity in the paretic lower limb frequently causes these walking disabilities, and the gold standard treatment is intramuscular injection of…
- Trial name
- Lokomat (NCT03659266)
- Testing
- Robotic walking rehabilitation by Lokomat®, Conventional walking rehabilitation
- Where
- France
- Volunteers
- 34 people
- Sponsor
- Assistance Publique Hopitaux De Marseille
Intellectual Disability
We Walk Plus Study for Older Adults With Intellectual Disabilities
Determine the feasibility and acceptability of We Walk Plus intervention to promote physical activity and improve cognition for older adults with intellectual disabilities (ID).
- Trial name
- NCT04573530
- Testing
- We Walk Plus Intervention
- Where
- 2 sites in United States
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- University of Illinois Chicago
Breast Cancer, Peripheral Neuropathies
The Effect of Walking Exercise Based on TOUS on Peripheral Neuropathy and Arthralgia-Myalgia in Women With Breast Cancer
Peripheral neuropathy from paclitaxel is a cause for concern. This situation also affects the patient, family and healthcare professionals. All health personnel are responsible for its care.
- Conditions
- Breast Cancer, Peripheral Neuropathies, Arthralgia, Myalgia
- Trial name
- NCT05448209
- Testing
- walking exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 82 people
- Sponsor
- Necmettin Erbakan University
Hearing Loss, Functional
Fitness, Hearing and Quality of Life in Older Adults With Hearing Loss. Walk, Talk and Listen for Your Life
This study examines the effect of an exercise and health education/auditory rehabilitation and socialization intervention on functional fitness, hearing handicap and psychosocial distress measures in older adults with hearing…
- Trial name
- WTL (NCT02662192)
- Testing
- Exercise + health education+ auditory rehabilitation, auditory rehabilitation alone
- Where
- Canada
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Stroke Patients
Virtual Reality-Based Rehabilitation After Stroke: A Randomized Controlled Trial
To determine the added value of integrating virtual reality therapy (VRT) based balance training into conventional therapy (CT) for improving balance and gait in subacute stroke patients, and to evaluate the usability and patient…
- Trial name
- NCT07409116
- Testing
- Standard Conventional Rehabilitation, Virtual Reality Rehabilitation Program
- Where
- Belgium
- Volunteers
- 34 people
- Sponsor
- Erasme University Hospital
Cerebral Palsy
Quantifying Energetic Demands of Walking for People With Cerebral Palsy
The purpose of this study is to examine the underlying mechanisms that contribute to high energy costs for people with cerebral palsy (CP) as they walk.
- Trial name
- NCT04303078
- Testing
- Varying levels of harness support during walking
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- University of Washington
Alzheimer's Disease
Effect of Walking on Brain Fuel Consumption in Mild Alzheimer's Disease
The aim of this study is to evaluate the effect of a 3-month walking program on brain energy metabolism in patient with mild Alzheimer's disease (AD).
- Trial name
- MAL (NCT02708485)
- Testing
- Physical exercise
- Where
- Canada
- Volunteers
- 15 people
- Sponsor
- Université de Sherbrooke
Cerebral Palsy, Muscle Hypertonia
Hypertonia in Patients With Cerebral Palsy
This study will classify types of hypertonia in patients with cerebral palsy and determine if the classifications are reasonable in relation to the functional task of walking. Hypertonia is an abnormal increase in muscle tension.
- Trial name
- NCT00123708
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Cerebral Palsy
Intensive Home-based Treadmill Training and Walking Attainment in Young Children With Cerebral Palsy
This study is designed to find the optimal dosage of home-based treadmill training needed to accelerate walking onset and to examine the long-term effects on the child's walking activity.
- Trial name
- NCT02424526
- Testing
- home-based treadmill training, Treadmill
- Where
- 2 sites in United States
- Volunteers
- 19 people
- Sponsor
- California State University, Sacramento
Multiple Sclerosis
Characterization of the Effects of Prolonged-release Fampridine on Ambulatory Function in Patients With Multiple Sclerosis
The objective of the present investigator-initiated mono-center trial to be performed at the Department of Neurology of the University Hospital Zurich is a detailed characterization of the effects of prolonged-release fampridine…
- Trial name
- FAMPKIN (NCT01576354)
- Testing
- Prolonged-release Fampridine
- Where
- Switzerland
- Volunteers
- 70 people
- Sponsor
- University of Zurich
Parkinson Disease, Rhythm
The Effects of a Single Session of Rhythmic Movement Program on Selected Biopsychological Parameters in PD Patients
The aim of the present study is to examine the acute effects of a specially designed musicokinetic (MSK) program for patients with Parkinson's disease (PD) on a) anxiety levels b) select kinematic and kinetic parameters, and c)…
- Trial name
- NCT05973565
- Testing
- Musicokinetic Training
- Where
- United Kingdom
- Volunteers
- 13 people
- Sponsor
- University of Wolverhampton
Cardiovascular, Diabetes
Home-Based Walking Study in Older Adults With Type 2 Diabetes
Older persons with diabetes have a harder time maintaining blood pressure when standing up. When blood pressure drops when standing up, fainting may occur.
- Conditions
- Cardiovascular, Diabetes, Orthostatic Hypotension, Type 2 Diabetes
- Trial name
- NCT00824330
- Testing
- Control Phase; Exercise Phase
- Where
- 2 sites in Canada
- Volunteers
- 13 people
- Sponsor
- University of British Columbia
Exercise, Stroke
Multimodal Exercise Training Poststroke
Individuals poststroke with gait and balance impairment are typically less active and have low levels of physical fitness. Improving fitness level while also improving gait and balance is very important.
- Trial name
- NCT03174392
- Testing
- Resistance Based Training, Speed Based Training
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- University of Alabama at Birmingham
Stroke
Reproducibility of fNIRS Parameters During Walking
Brain activation can be studied using the Functional Near InfraRed Spectroscopy (fNIRS). It was shown that CPF activation during walking and during dual task could be different in stroke patients and in healthy subjects.
- Trial name
- REPROXY (NCT04882930)
- Testing
- Functional Near-Infrared Spectroscopy (fNIRS)
- Where
- 3 sites in France
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Régional d'Orléans
Stroke, Stroke, Acute
A Multisite Exploration of Balance Perturbations With and Without Body Weight Support
ZeroG is an FDA-listed robotic body weight support system (BWSS). Mounted on an overhead track, patients are fitted in a harness system tethered to said track, and are able to practice gait and balance activities without the risk…
- Conditions
- Stroke, Stroke, Acute, Balance; Distorted, Balance; Impairment
- Trial name
- NCT05110300
- Testing
- Body weight support system control group, Body weight support system with balance perturbations
- Where
- 4 sites in United States
- Volunteers
- 114 people
- Sponsor
- Gaylord Hospital, Inc
Multiple Sclerosis
Clinical Pilates Training for Persons With Multiple Sclerosis
Multiple sclerosis (MS) is a chronic-progressive and neurodegenerative disease. Thus, exercise programs are needed to maintain and increase functional status of persons with MS (pwMS).
- Trial name
- NCT03502772
- Testing
- Pilates exercises, Home exercise program
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people
- Sponsor
- Dokuz Eylul University
Multiple Sclerosis
Trekking Poles to Aid Multiple Sclerosis Gait Impairment
In this study, the investigators will examine a sample of persons with multiple sclerosis (MS) to determine whether their walking function and ability is different depending on which walking assistive device is used.
- Trial name
- TRAMS (NCT02227524)
- Testing
- No device, Single-point cane (SPC), Four-point cane (FPC)
- Where
- United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Rowan University
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