Clinical trials: Ambulation Disorder, Neurologic
Fibromyalgia, Physical Function
The Role of Resilience for Physical Functioning of Patients With Fibromyalgia Syndrome Using the 6-Min Walk Test
Fibromyalgia (FM) is a prevalent chronic pain disorder, characterized by widespread musculoskeletal pain and fatigue that is associated with significant functional limitations. Its mechanisms are only partially understood.
- Conditions
- Fibromyalgia, Physical Function, Six-minute Walk Test
- Trial name
- 6MWT (NCT07611539)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Florida
Spinal Cord Injuries, Spinal Cord Diseases
Comparison of Transcutaneous and Epidural Spinal Stimulation for Improving Function
Incomplete spinal cord injuries (SCI) are the most frequent neurologic category, comprising 66.7% of all SCI cases. People with incomplete SCI may retain some ability to move the legs and therefore the capacity to regain walking.
- Conditions
- Spinal Cord Injuries, Spinal Cord Diseases, Central Nervous System Diseases, Nervous System Diseases
- Trial name
- NCT04043715
- Testing
- Transcutaneous spinal stimulation, Epidural spinal stimulation
- Where
- United States
- Sponsor
- University of Washington
Spinal Cord Injuries
Stepping Training Using External Feedback in Spinal Cord Injury Patients
Does a 4-week stepping training program with or without external feedback clinically change functional ability and reduce risk of fall of ambulatory patients with iSCI? Are there significant differences between 4-weeks stepping…
- Trial name
- NCT03254797
- Testing
- Stepping training with feedback, Stepping training without feedback
- Where
- Thailand
- Volunteers
- 44 people
- Sponsor
- Khon Kaen University
Obstructive Sleep Apnea, Obesity
Exercise Capacity and Daily Physical Activity in Obese Subjects With Treated Obstructive Sleep Apnea
Obesity is very common worldwide and breathing problems at night (obstructive sleep apnea, OSA) are common in obesity. Despite the best treatment, obesity and OSA are linked to early death from heart problems.
- Trial name
- NCT01930513
- Where
- Canada
- Volunteers
- 16 people
- Sponsor
- West Park Healthcare Centre
Cerebral Small Vessel Disease, Repetitive Transcranial Magnetic Stimulation (rTMS)
Effect of High Frequency Cerebellar Repetitive Transcranial Magnetic Stimulation on Functional Ambulation of Patients With Cerebral Small Vessel Disease
This study aims to evaluate the effect of repetitive transcranial magnetic stimulation (rTMS) applied over the cerebellum on gait performance and balance in patients with cerebral small vessel disease (CSVD).
- Conditions
- Cerebral Small Vessel Disease, Repetitive Transcranial Magnetic Stimulation (rTMS), Balance, Gait Disorders
- Trial name
- NCT07531797
- Testing
- Repetitive Transcranial Magnetic Stimulation
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Ain Shams University
Stroke, Cerebral Vascular Disorders
Discrete Versus Rhythmic Gait Training
The objective of this study is to compare the effects of novel versus standard locomotor training using a robotic gait orthosis (LT-RGO) after stroke.
- Trial name
- NCT02650440
- Testing
- Novel Protocol, Standard Protocol
- Where
- Brazil
- Volunteers
- 20 people
- Sponsor
- Thais Amanda Rodrigues
Stroke
Responses to Backward Walking Training Post-Stroke
Approximately 15,000 Veterans are hospitalized for stroke each year with new cases costing an estimated $111 million for acute inpatient, $75 million for post-acute inpatient, and $88 million for follow-up care over 6 months…
- Trial name
- BRAVE (NCT04928482)
- Testing
- Backward Walking Training
- Where
- 2 sites in United States
- Volunteers
- 48 people
- Sponsor
- VA Office of Research and Development
Diabetic Foot
Effect of Subtalar and Talocrural Joint Mobilization on Foot Ranges and Posture in Diabetic Patients
The aim of this research is to determine the Effects of mobilizations on foot ranges and posture in people with Type 2 Diabetes Mellitus. Randomized controlled trials will be done at Dr.
- Trial name
- NCT05922280
- Testing
- subtalar and talo-crural mobilization, International Working Group of the Diabetic Foot care guidelines
- Where
- Pakistan
- Volunteers
- 41 people
- Sponsor
- Riphah International University
Developmental Delay, Cerebral Palsy
Mobility Training to Improve Motor Behavior in Toddlers With or at Risk for Cerebral Palsy: A Pilot Study
Background: People who have cerebral palsy often have difficulty walking and moving their legs. Cerebral palsy is sometimes not identified until a child is almost 2 years of age, which means that early motor skill development can…
- Trial name
- NCT01253083
- Testing
- mobility training with dynamic body weight support
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- National Institutes of Health Clinical Center (CC)
Multiple Sclerosis, Multiple Sclerosis (MS) - Relapsing-remitting
Acute Intermittent Hypoxia Combined With Gait Training in Multiple Sclerosis
This interventional, randomized, sham-controlled study will examine whether Acute Intermittent Hypoxia (AIH) delivered immediately before Myoelectric Interface Neurorehabilitation Training (MINT)-based locomotor training improves…
- Conditions
- Multiple Sclerosis, Multiple Sclerosis (MS) - Relapsing-remitting, Multiple Sclerosis (MS) Primary Progressive, Multiple Sclerosis (MS) Secondary Progressive
- Trial name
- MINT (NCT07631923)
- Testing
- Acute Intermittent Hypoxia (AIH), Myoelectric Interface Neurorehabilitation Training (MINT)
- Volunteers
- 35 people
- Sponsor
- Shirley Ryan AbilityLab
Stroke
Split-Belt Gait Retraining in Subacute Stroke
Stroke is a leading cause of long-term disability in adults. Although many individuals regain independent walking ability following stroke, nearly 50% experience persistent gait impairments characterized by asymmetrical walking…
- Trial name
- NCT07601633
- Testing
- Split-belt walking training
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- University of British Columbia
Stroke, Gait Impairment
Transcranial Direct Current Stimulation for Post-stroke Gait Rehab
Stroke affects upwards of 800,000 Americans every year and has an enormous impact on the well-being of the American Veteran population with 6,000 new stroke admissions every year.
- Trial name
- NCT03666533
- Testing
- Active transcranial Direct Current Stimulation
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- VA Office of Research and Development
Multiple Sclerosis
Safety and Efficacy Study of Oral Fampridine-SR in Patients With Multiple Sclerosis
Multiple Sclerosis (MS) is a disorder of the body's immune system that affects the Central Nervous System (CNS). Normally, nerve fibers carry electrical impulses through the spinal cord, providing communication between the brain…
- Trial name
- NCT00053417
- Testing
- 10 milligram (mg) fampridine-SR (4-aminopyridine, 4-AP), 15 mg fampridine-SR (4-aminopyridine, 4-AP), 20 mg fampridine-SR (4-aminopyridine, 4-AP)
- Where
- 25 sites in United States, Canada
- Volunteers
- 206 people
- Sponsor
- Acorda Therapeutics
Osteoarthritis Knees Both, Pain, Chronic
Investigation of the Effectiveness of a Structured Squat-based Program in Knee Osteoarthritis Rehabilitation
The main purpose of the study is to examine the effect of squat-based exercise approach in individuals with knee osteoarthritis.
- Conditions
- Osteoarthritis Knees Both, Pain, Chronic, Walking, Difficulty
- Trial name
- NCT04588558
- Testing
- Flywheel exercise, Home exercise, Electrotherapy group
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people
- Sponsor
- Istanbul Medipol University Hospital
Gait Disorder, Sensorimotor, Cognitive Disorder
Thinking, Walking Outcomes by Type of Exercise
The purpose of this research study is to compare two different exercise treatments for walking problems in older adults. The investigators want to determine if participation in the exercise programs will improve walking and…
- Trial name
- 2-STEP (NCT01635348)
- Testing
- motor skill gait exercise, aerobic gait intervention
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Spinal Cord Injury
Effects of 4-AP on Functional SCI Recovery
The purpose of this study is to test a strategy to potentiate functional recovery of lower limb motor function in individuals with spinal cord injury (SCI). The FDA approved drug, Dalfampridine (4-AP).
- Trial name
- NCT05447676
- Testing
- Dalfampridine, STDP stimulation, Exercise training
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- Shirley Ryan AbilityLab
Stroke
Physiotherapy in Order to Improve Walking Capacity and Participation in Chronic Stroke Subjects
In hemiplegic stroke patients, gait performance is affected by impaired walking endurance. Evidence has shown that higher exercise intensity improves cardiovascular fitness, while greater dose in task repetition benefits…
- Trial name
- NCT02543450
- Testing
- Cardiovascular and task-oriented training, Upper limb strength training program
- Where
- Spain
- Volunteers
- 15 people
- Sponsor
- University of Valencia
Injuries, Spinal Cord
The WISE Trial - Walking Improvement for SCI With Exoskeleton
A randomized, controlled trial comparing exoskeleton gait training with standard gait training or no gait training in community-dwelling participants with chronic incomplete spinal cord injury
- Trial name
- WISE (NCT02943915)
- Testing
- Ekso GT Rehabilitation Therapy, Body Weight Supported (BWS) Treadmill Training
- Where
- 10 sites in United States
- Volunteers
- 45 people
- Sponsor
- Ekso Bionics
Huntington Disease, Lewy Body Disease
Treadmill Walking in Individuals With Dementia With Lewy Bodies and Huntington's Disease
Individuals with Dementia with Lewy Bodies (DLB) and Huntington's disease (HD) experience balance and walking problems that lead to falls.
- Trial name
- NCT02268617
- Testing
- Treadmill Walking
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- Ohio State University
Spinal Cord Injury
Restoring Walking With a Powered Exoskeleton After Spinal Cord Injury
Powered exoskeletons have emerged recently, promising to offer walking to individuals with severe spinal cord injury who are unable to walk.
- Trial name
- NCT02322125
- Testing
- ReWalk
- Where
- Canada
- Volunteers
- 12 people
- Sponsor
- University of Alberta
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