Clinical trials: Ambulation Disorder, Neurologic
Parkinson Disease
Acute Effects of Whole Body Vibration for Individuals With Parkinson Disease
This is an exploratory study to assess the impact of whole body vibration on backward walking speed in people with Parkinson disease.
- Trial name
- NCT06352905
- Testing
- Whole body vibration (WBV), Control
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- Baylor University
Cerebral Palsy, Spastic
Whole Body Vibration in Children With Cerebral Palsy
Some positive effects of whole body vibration applications in reducing spasticity, improving walking ability, and increasing walking speed have been reported in children with CP, but the evidence is not strong enough.
- Trial name
- CP (NCT05636241)
- Testing
- conventional physiotherapy program, whole body vibration training program
- Where
- Turkey (Türkiye)
- Volunteers
- 13 people
- Sponsor
- Kutahya Health Sciences University
Neurodegenerative Disease, EEG
Mindfulness Walking Intervention to Enhance Resilience (iWalk)
This study is a randomized controlled trial of the walking meditation intervention (iWalk) program, a multi-component intervention integrating walking meditation, education, and group sessions designed to enhance resilience in…
- Conditions
- Neurodegenerative Disease, EEG, Mindfulness, Adults
- Trial name
- iWalk (NCT07285954)
- Testing
- iWalk Program
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of Illinois at Urbana-Champaign
Conditions
Exoskeleton for Post-Stroke Recovery of Ambulation
To determine the effect of using a robotic exoskeleton to allow walking practice after stroke, compared to usual physiotherapy care, on recovery of walking ability and secondary outcomes.
- Trial name
- ExStRA (NCT02995265)
- Testing
- Exoskeleton Program, Usual Care Program
- Where
- 3 sites in Canada
- Volunteers
- 36 people
- Sponsor
- University of British Columbia
Multiple Sclerosis, Gait Disorders, Neurologic
TRAIN-BW: Backward Walking Training in Multiple Sclerosis
Individuals with multiple sclerosis (MS) experience in impairments in mobility and cognition that increase the risk for accidental falls. More than 50% of individuals with MS experience injurious falls within a 6-month period.
- Conditions
- Multiple Sclerosis, Gait Disorders, Neurologic, Accidental Fall
- Trial name
- TRAIN-BW (NCT04091464)
- Testing
- Backward Walking Training, Forward Walking Training
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- Wayne State University
Spinal Cord Injury
Spinal Cord Stimulation for Spinal Cord Injury Patients - Regain Walk and Alleviate Pain
The study aims to examine the plausible interventional mechanisms underlying the effects of epidural spinal cord stimulation.
- Trial name
- NCT05433064
- Testing
- Epidural Stimulator
- Where
- Taiwan
- Volunteers
- 12 people
- Sponsor
- Buddhist Tzu Chi General Hospital
Cerebral Palsy, Cerebral Palsy Spastic Diplegia
Evaluation of the Applicability and Reliability of the Three Meter Backwalk Test in Children With Cerebral Palsy (CP)
Cerebral palsy (CP) is a non-progressive disturbance in the development of movement and posture that occurs in the prenatal or postnatal period, causing activity limitations.
- Conditions
- Cerebral Palsy, Cerebral Palsy Spastic Diplegia, Hemiplegic Cerebral Palsy, Gait, Hemiplegic
- Trial name
- NCT04653363
- Testing
- assessments
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Sanko University
Traumatic Brain Injury
Personalized Cognitive Integrated Motor Training Using Virtual Reality to Improve Gait and Balance
Problems with walking and balance are common after traumatic brain injury (TBI). Walking and balance problems limit independence and increase risk for injuries due to falls.
- Trial name
- CMT (NCT06473987)
- Testing
- Personalized cognitive-sensorimotor VR/AR training, Traditional dual-task training, Standard of Care
- Where
- United States
- Volunteers
- 135 people
- Sponsor
- Kessler Foundation
Multiple Sclerosis, Ambulation Difficulty
Effects of a Home Based Walking Program Using Rhythmic Auditory Stimulation in Patients With Multiple Sclerosis
Rhythmic Auditory Stimulation (RAS) is a music therapy technique that provides rhythmic auditory cues (like a beat) to help improve patients' movements, especially when walking.
- Trial name
- NCT02065284
- Testing
- Rhythmic Auditory Stimulation (RAS)
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- The Cleveland Clinic
Cerebral Palsy
A Pilot Study of the Effect of Botulinum Toxin Type a (Dysport®, Abobotulinum Toxin A) Injection on Changes in Musculotendinous Length and Dynamics of Hamstring Muscles During Gait in Children With Spastic Cerebral Palsy Walking With Excessive Knee Flexion
This is a longitudinal, prospective, and open-label interventional study in a single center. We will investigate the effect of single injection in each patient.
- Trial name
- NCT02917967
- Testing
- Botulinum toxin injection
- Where
- South Korea
- Volunteers
- 31 people
- Sponsor
- Yonsei University
Stroke, Healthy Volunteers
Effects of Rehabilitation Robots-Morning Walk in Individuals With Hemiparesis
In this study, our objective is to explore and evaluate interventions to improve the process of recovery following a stroke. The main focus is on enhancing symmetrical walking patterns in adults who have experienced neurological…
- Trial name
- NCT06374706
- Testing
- Morning Walk training for stroke, Morning Walk training for healthy
- Where
- United States
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- The University of Texas Medical Branch, Galveston
Parkinson Disease
Effects of Group Physical Therapy on Walking Speed in Patients With Parkinson Disease
Parkinson disease is a progressive neurologic disorder characterized by motor impairments which alter the walking capacity, and lead to reduced walking speed, decreased stride length and increased double support time.
- Trial name
- NCT04187963
- Testing
- Physical therapy
- Volunteers
- 60 people
- Sponsor
- Iuliu Hatieganu University of Medicine and Pharmacy
Spinal Cord Diseases
Body Weight Supported Training Study
Successful ambulation at home and in the community is the main goal of gait training after incomplete spinal cord injury. Many different treatment approaches have been recommended to achieve this goal.
- Trial name
- NCT03534518
- Testing
- BWS overground training, BWS treadmill training
- Where
- Switzerland
- Volunteers
- 14 people
- Sponsor
- University of Zurich
Multiple Sclerosis
Resistance Training and Corticospinal Excitability in Multiple Sclerosis
The goal of the present study is to investigate effects of progressive resistance training on central nervous system functioning (corticospinal excitability (CSE)) and walking capacity in persons with multiple sclerosis (pwMS).
- Trial name
- NEXIMS (NCT06374108)
- Testing
- Progressive resistance training
- Where
- 2 sites in Denmark
- Volunteers
- 54 people
- Sponsor
- University of Aarhus
Stroke, Cerebrovascular Accident
The Effectiveness of Body Weight Supported Treadmill Training in Stroke Patients
In this study, the investigators aimed to evaluate the effects of exercise on body weight-supported treadmill in stroke patients on gait parameters, activity, body functions and quality of life, and to determine whether it has an…
- Conditions
- Stroke, Cerebrovascular Accident, Gait Disorders, Neurologic, Walking, Difficulty
- Trial name
- NCT04597658
- Testing
- Bodyweight supported treadmill training (BWSTT), Conventional rehabilitation
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Istanbul University
Parkinson Disease, Prodromal Stage
Slow-SPEED-NL: Slowing Parkinson's Early Through Exercise Dosage-Netherlands
The goal of this clinical trial is to investigate the feasibility if a remotely administered smartphone app can increase the volume and intensity of physical activity in daily life in patients with isolated Rapid Eye Movement…
- Conditions
- Parkinson Disease, Prodromal Stage, Neurodegenerative Diseases, Parkinsonian Disorders
- Trial name
- Slow-SPEED-NL (NCT06193252)
- Testing
- Increase of physical activity volume and intensity with the use of a motivational smartphone application
- Where
- Netherlands
- Volunteers
- 110 people
- Sponsor
- Radboud University Medical Center
Chuvash Polycythemia, Cerebrovascular Disease
Pulmonary Hypertension, Hypoxia and Sickle Cell Disease
The study will look at the risk factors for pulmonary hypertension (high blood pressure in the lungs) in children and adolescents with sickle cell anemia (SCA) and examine the role of hypoxia (oxygen shortage) in the disease.
- Conditions
- Chuvash Polycythemia, Cerebrovascular Disease, Pulmonary Hypertension, Sickle Cell Anemia
- Trial name
- NCT00495638
- Where
- 7 sites in United States, Russia
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Multiple Sclerosis
Effects of Functional Electrical Stimulation Cycling Versus Cycling Only on Walking and Quality of Life in MS
This study will seek to determine the benefits that FES-LE cycling has over cycling alone on walking performance and quality of life in people with multiple sclerosis.
- Trial name
- MSCycling (NCT02606604)
- Testing
- RT 300: Lower Extremity Cycling
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Stony Brook University
Cerebral Palsy
Can Gait Analysis and Ultrasound Detect a Change in Calf Musculature in Children With Cerebral Palsy?
ORLAU is a clinical department of the Robert Jones and Agnes Hunt Orthopaedic Hospital. We treat patients with a wide range of movement disorders affecting their walking or arm function.
- Trial name
- NCT04290689
- Testing
- Botulinum Toxin-A injection, Serial casting stretching
- Where
- United Kingdom
- Volunteers
- 20 people
- Sponsor
- Robert Jones and Agnes Hunt Orthopaedic and District NHS Trust
Spinal Cord Injury
Functional Electrical Stimulation-Assisted Walking: Reduction of Secondary Complications Due to Spinal Cord Injury
The purpose of this study is to evaluate whether an aerobic and resistance training program or a functional electrical stimulation-assisted Walking program is more effective for reducing health complications related to spinal…
- Trial name
- NCT00201968
- Testing
- Compex Motion Stimulator, Conventional Exercise
- Where
- Canada
- Volunteers
- 32 people
- Sponsor
- Ontario Neurotrauma Foundation
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