Clinical trials: Ambulation Disorder, Neurologic
Stroke, Hemiparesis
Long Term Split Belt Treadmill Training for Stroke Recovery
The purpose of this study is to determine whether split belt or conventional treadmill training can be used to treat walking pattern deficits from stroke and to determine whether this improves gait asymmetry and metabolic…
- Trial name
- NCT01646216
- Testing
- Split belt treadmill
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- Hugo W. Moser Research Institute at Kennedy Krieger, Inc.
Cerebral Palsy (CP)
Cerebral Palsy: Ankle Foot Orthoses - Footwear Combinations
Ambulatory children with cerebral palsy (CP) demonstrate altered lower limb biomechanical alignment in walking (e.g. excessive hip/knee flexion or equinus during stance) and experience walking activity limitations that negatively…
- Trial name
- CP-AFOFC (NCT03756571)
- Testing
- Ankle Foot Orthoses-Footwear Combination, Traditional Solid Ankle AFO (TSAFO)
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- Seattle Children's Hospital
Stroke
Locomotor Training (Walking Therapy) Post Stroke
This is a research study to examine a new type of walking therapy for people after they have had a stroke. We will study how people move and how their muscles work to see how the therapy helps people to walk better and to see how…
- Trial name
- NCT00715299
- Testing
- locomotor training
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- US Department of Veterans Affairs
Stroke
Mechanisms of Walking Recovery After Stroke
Subjects with stroke will have behavioral testing and brain imaging before and after a 4-week control period and a 4-week exercise intervention.
- Trial name
- NCT02858349
- Testing
- No intervention, High-intensity interval training
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Cincinnati
Arthritis, Gout
Phone-Based Based Walk With Ease Program for Adults With Arthritis
The objective of this study is to examine the short-term (6-weeks and 6 months) and long-term (1 year) effects of a phone-based version of Walk With Ease intervention.
- Conditions
- Arthritis, Gout, Fibromyalgia, Rheumatoid Arthritis
- Trial name
- NCT05289544
- Testing
- Phone-Based Walk With Ease
- Where
- United States
- Volunteers
- 267 people, healthy volunteers welcome
- Sponsor
- University of South Carolina
Spinal Cord Injuries, Inpatient
Exoskeletal-Assisted Walking in SCI Acute Inpatient Rehabilitation
The purpose of this research study is to test the effect of early exoskeletal-assisted walking (EAW) training (combined into regular acute inpatient rehabilitation (AIR)) on improving functional recovery and reducing pain and…
- Trial name
- NCT04221373
- Testing
- Ekso™ powered exoskeleton, Standard of care
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Parkinson Disease
Robotic Walking Device to Improve Mobility in Parkinson's Disease
This Phase II randomized controlled trial proposes to examine the impact of long-term use of a novel light-weight and wearable assistive robotic device, called the Honda Walking Assist (HWA) device, to improve mobility in the…
- Trial name
- NCT03751371
- Testing
- Training with HWA device, Usual Care
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Ohio State University
Duchenne Muscular Dystrophy
Safety and Efficacy Study of IGF-1 in Duchenne Muscular Dystrophy
The purpose of this study is to determine whether IGF-1 therapy improves or preserves muscle function in Duchenne Muscular Dystrophy (DMD).
- Trial name
- NCT01207908
- Testing
- IGF-1
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Parkinson Disease
Walking and mHealth to Increase Participation in Parkinson Disease
Identifying effective ways to improve function, slow decline and reduce disability is a high priority for people living with Parkinson disease and other chronic conditions.
- Trial name
- WHIPPD (NCT03517371)
- Testing
- mHealth delivered exercise program, Exercise only
- Where
- 2 sites in United States
- Volunteers
- 140 people
- Sponsor
- Boston University Charles River Campus
SCI - Spinal Cord Injury, Incomplete Spinal Cord Injury
Stimulation to Enhance Walking Post-SCI
This pilot study will investigate the effects of transcutaneous direct current stimulation (tsDCS) on walking function in individuals with incomplete spinal cord injury.
- Trial name
- NCT03702842
- Testing
- Soterix Medical tsDCS stimulator, Locomotor training
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- University of Florida
Multiple Sclerosis
Methylphenidate to Improve Balance and Walking in MS
Methylphenidate is an amphetamine-like psychomotor stimulant drug currently approved for the treatment of attention-deficit hyperactivity disorder (ADHD), postural orthostasis tachycardia syndrome and narcolepsy.
- Trial name
- NCT01896700
- Testing
- Methylphenidate
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Oregon Health and Science University
Stroke
Power Training Post-stroke
Hemiparesis, strictly defined as (muscular) weakness affecting one side of the body, is seen in three-quarters of individuals following stroke.
- Trial name
- NCT01970592
- Testing
- POWER training
- Where
- United States
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Spinal Cord Injury
Powered Exoskeletons in Persons With SCI
Background Veterans with spinal cord injury (SCI) have many adverse secondary medical and quality of life (QOL) changes as a result of immobilization.
- Trial name
- (PEPSCI) (NCT02658656)
- Testing
- ReWalk 6.0
- Where
- 15 sites in United States
- Volunteers
- 424 people
- Sponsor
- VA Office of Research and Development
Spinal Cord Injury
Precision Versus Endurance Training to Improve Walking After Chronic Incomplete SCI
The objective of the study was to determine the efficacy of two forms of physical therapy training, one emphasizing precise, visually guided walking over obstacles and on targets (Precision Training), the other emphasizing mass…
- Trial name
- NCT01765153
- Testing
- Endurance, Precision
- Where
- Canada
- Volunteers
- 21 people
- Sponsor
- University of Alberta
Stroke
Improving Ambulation Post Stroke With Robotic Training
The purpose of this research study is to look at a new rehabilitation technique for individuals who have suffered a stroke and have difficulties walking.
- Trial name
- NCT00975156
- Testing
- Physical Therapy, Lokomat
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- The University of Texas Health Science Center, Houston
Ataxia - Other
Assistive Devices and Gait in Persons With Ataxia
The purpose of this research study is to determine the effect of various assistive devices on gait quality and balance for individuals with cerebellar ataxia.
- Trial name
- NCT06866353
- Testing
- Walking with different walkers
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Texas Southwestern Medical Center
Multiple Sclerosis
Effects of Functional Electrical Stimulation Cycling Versus Cycling Only on Walking and Quality of Life in MS
This study will seek to determine the benefits that FES-LE cycling has over cycling alone on walking performance and quality of life in people with multiple sclerosis.
- Trial name
- MSCycling (NCT02606604)
- Testing
- RT 300: Lower Extremity Cycling
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Stony Brook University
Acute Stroke
Metabolic Costs of Walking Post Stroke
This will be a randomized, matched-group study to compare the cardiopulmonary / metabolic benefits for persons post stroke that learn to walk utilizing early treadmill training post-acute stroke to persons post stroke that learn…
- Trial name
- NCT02108912
- Testing
- ESTT, Traditional outpatient
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- University of Texas Southwestern Medical Center
Stroke
Promoting Recovery Optimization With WALKing Exercise After Stroke
Stroke survivors, as a group, are extremely inactive and this has serious consequences for them, including an increased risk of a second stroke and developing other diseases.
- Trial name
- PROWALKS (NCT02835313)
- Testing
- FAST alone, FAST+SAM, SAM alone
- Where
- United States
- Volunteers
- 250 people
- Sponsor
- University of Delaware
Multiple Sclerosis
Muscle Vibration in MS to Improve Walking
The primary goal of this pilot study is to explore the feasibility of cyclic vibration (CV) of the lower extremity muscles to improve walking in individuals with gait deficits from multiple sclerosis (MS).
- Trial name
- NCT03403413
- Testing
- muscle vibration during walking
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- VA Office of Research and Development