Clinical trials: Amenorrhea
Endometriosis
Compliance and Endometriosis
Endometriosis is defined as the presence of hormone-dependent endometrial tissue outside the uterine cavity. It is a chronic, painful and often disabling pathology during the normal activities of daily life.
- Trial name
- NCT05619757
- Testing
- Compliance with medical treatment for endometriosis
- Where
- France
- Volunteers
- 58 people
- Sponsor
- Hospices Civils de Lyon
Primary Amenorrhea With Hypogonadotropic Hypogonadism
LutrePulse Hypogonadotropic Hypogonadism
To compare the ovulation rate in women with primary amenorrhea with hypogonadotropic hypogonadism following pulsatile gonadotropin-releasing hormone (GnRH) treatment using the OmniPod pump versus placebo
- Trial name
- NCT01976728
- Testing
- Gonadorelin acetate subcutaneous (SC) 10 μg/pulse as a fixed dose, administered via. OmniPod pump, Gonadorelin acetate SC 15 μg/pulse as a fixed dose, administered via. OmniPod pump, Gonadorelin acetate SC 20 μg/pulse as a fixed dose, administered via. OmniPod pump
- Where
- 35 sites in United States, Canada
- Volunteers
- 39 people
- Sponsor
- Ferring Pharmaceuticals
Menstrual Irregularity
Timing of Energy Availability on Menstrual Cycle Function
The primary aim of this clinical trial is to evaluate how fasted prolonged exercise may influence circulating reproductive hormones (i.e., estradiol, progesterone, luteinizing hormone) and menstrual cycle length when energy…
- Trial name
- FAST (NCT06471582)
- Testing
- Artificially Sweetened Carbohydrate Beverage, Artificially Sweetened Beverage
- Where
- United States
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Colorado Springs
Misoprostol, Drug-induced Abortion
Compare the Different Routes of Administration of Misoprostol During Medicinal Abortion Between 7 and 9 Weeks of Amenorrhoea (SA)
In France, drug-induced abortion is allowed up to 9SA, after which the surgical route is preferred. Mifepristone 600mg is used 36-48 hours before the introduction of Misoprostol. This is recommended orally at a dose of 400 μg.
- Trial name
- Misoprostol (NCT03140384)
- Testing
- Assess the efficacy and side effects of Misoprostol according to the route of administration
- Where
- France
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Infertility, Female, Anovulatory Infertility
Autologous PRP Intra Ovarian Infusion to Restore Ovarian Function in Menopausal Women
Autologous PRP intra ovarian infusion may restore ovarian function, may promote folliculogenesis and may improve hormonal profile of women in menopause.
- Conditions
- Infertility, Female, Anovulatory Infertility, Menopause, Amenorrhea
- Trial name
- PRP (NCT03916978)
- Testing
- Autologous PRP intra ovarian infusion, Autologous PFP intra ovarian infusion
- Where
- Greece
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Genesis Athens Clinic
Amenorrhea
A Trial to Evaluate DR-2021 in Women With Secondary Amenorrhea
This is a multicenter trial to compare the effectiveness of 4 doses of DR-2021 with placebo and oral micronized progesterone in inducing withdrawal bleeding in women with secondary amenorrhea.
- Trial name
- NCT00196391
- Testing
- DR-2021a, DR-2021b, DR-2021c
- Where
- 27 sites in United States
- Volunteers
- 180 people
- Sponsor
- Duramed Research
Pregnancy During Breastfeeding, Lactational Amenorrhea Method
Emergency Contraception as a Back up of Lactational Amenorrhea Method(LAM)
Prolonged breast-feeding is an encouraged tradition in Egypt. Breastfeeding is associated with variable degrees of amenorrhea and infertility but there is a risk of resumption of fertility and therefore, of conception during…
- Trial name
- ECLAM (NCT01111929)
- Testing
- Counseling for LAM+ LNG-EC
- Volunteers
- 1,174 people
- Sponsor
- Assiut University
Menstruation Disturbances, Luteal Phase Defect
Bioenergetics of Exercise-Induced Menstrual Disturbances
Menstrual disturbances are frequently observed in physically active women and female athletes. Short term prospective studies have shown that diet and exercise interventions can lead to decreases in Luteinizing hormone (LH)…
- Conditions
- Menstruation Disturbances, Luteal Phase Defect, Amenorrhea, Oligomenorrhea
- Trial name
- BioE (NCT04938622)
- Testing
- Sedentary Control, Exercising control, 15 percent energy deficit
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Penn State University
Anorexia Nervosa, Hypothalamic Amenorrhea
Hormone Dynamics and Bone Mineral Density in Anorexia Nervosa v. Hypothalamic Amenorrhea
The purpose of this study is to determine whether the hormone dynamics in women with anorexia nervosa and hypothalamic amenorrhea is related to bone loss in those populations.
- Conditions
- Anorexia Nervosa, Hypothalamic Amenorrhea, Obesity
- Trial name
- NCT00556036
- Where
- United States
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Premature Birth
Study of the Short-term Mortality and Morbidity of Newborns Born at a Gestational Age <32 Weeks of Amenorrhea
An "outborn" birth is a premature birth that occurs in an unsuitable level center at the end of the child (unlike "inborn" births).
- Trial name
- OutBorn (NCT05150301)
- Where
- France
- Volunteers
- 134 people
- Sponsor
- University Hospital, Strasbourg, France
Primary Ovarian Insufficiency, Low Ovarian Reserve
Rejuvenation of Premature Ovarian Failure With Stem Cells
The ROSE-1 study is designed to determine the efficacy of bone marrow derived stem cell therapy on ovarian function recovery in subjects with idiopathic and other types of premature or primary ovarian failure (POF or POI) and low…
- Conditions
- Primary Ovarian Insufficiency, Low Ovarian Reserve, Premature Ovarian Failure
- Trial name
- ROSE-1 (NCT02696889)
- Testing
- ROSE-1 Protocol
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- University of Illinois at Chicago
Idiopathic Hypogonadotropic Hypogonadism, Hypothalamic Amenorrhea
Detailed Clinical, Biochemical and Genetic Characterization in Gonadotropin-releasing Hormone (GnRH) Deficiency Disorders
In this study, we will measure levels of reproductive hormones and metabolic markers in subjects with isolated GnRH deficiency disorders and compare them to healthy control populations.
- Trial name
- NCT01165619
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Osteopenia
Study to Evaluate the Safety and Efficacy of Seasonale for Treatment of Low Bone Mineral Density
This is a randomized, multicenter, placebo-controlled study to evaluate the effects of Seasonale, an extended-regimen oral contraceptive, on bone mineral density in adolescent females who have had their menstrual period but now…
- Trial name
- NCT00117260
- Testing
- Seasonale (levonorgestrel and ethinyl estradiol)
- Sponsor
- Duramed Research
Amenorrhea, Oligomenorrhea
Treatment of Menstrual Cycle Alterations in Adolescents
the aim of the present study is intended to evaluate how treatment with Myo-Inositol and Dioscorea Villosa can help improve menstrual cycle irregularities in adolescents, both with and without PCOS.
- Conditions
- Amenorrhea, Oligomenorrhea, PCOS (Polycystic Ovary Syndrome)
- Trial name
- HP-phD_Adolesc (NCT06800170)
- Testing
- myo-Inositol plus DIoscorea Villosa
- Where
- 2 sites in Georgia, Russia
- Volunteers
- 41 people
- Sponsor
- Lo.Li.Pharma s.r.l
Anorexia Nervosa
Effects of Anorexia Nervosa on Bone Mass in Adolescents
This study is to determine the effects of anorexia nervosa on bone mass and hormone levels in adolescents. Whether administration of estrogen, a normal hormone present during puberty, can help maintain bone development in girls…
- Trial name
- NCT00088153
- Testing
- Physiologic Estrogen/progesterone
- Where
- United States
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Secondary Amenorrhea
Effects of Dietary Nitrate in Women With Secondary Amenorrhea
Excessive exercise, disordered attitudes toward eating, physical and psychological stress, and/or hormonal imbalances may result in cessation of menstruation (secondary amenorrhea).
- Trial name
- NCT07019129
- Testing
- Beetroot Juice - Active
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Indiana University
Amenorrhea Secondary
Effects of Physical and Psychosocial Stress on Functional Hypothalamic Amenorrhea in Exercising Women
The goal of this clinical trial is to determine how changes in exercise and psychosocial stress may influence the risk of menstrual cycle irregularities in female runners and cyclists.
- Trial name
- FHA (NCT05967819)
- Testing
- Exercise Stress, Psychosocial Stress
- Where
- United States
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Colorado Springs
Neonatal Respiratory Distress, Preterm Birth
Study of the Feasibility of Early Lung Ultrasound in Neonatal Respiratory Distress in Premature Newborns Born Between 32 Weeks of Amenorrhea and 36 Weeks Plus 6 Days of Amenorrhea, Hospitalized in the Neonatal Pediatrics and Intensive Care Units of the Dijon University Hospital
Monocentric study carried out in the Neonatal and Intensive Care Units of the Dijon University Hospital. The objective is to evaluate the feasibility of performing a pulmonary ultrasound within 6 hours after admission in…
- Trial name
- REchoPP (NCT05737095)
- Testing
- Pulmonary ultrasound
- Where
- France
- Volunteers
- 69 people
- Sponsor
- Centre Hospitalier Universitaire Dijon
Estrogen Deficiency, Cardiovascular Disease (CVD)
Atherosclerosis, Immune Mediated Inflammation and Hypoestrogenemia in Young Women
The purpose of this study is to determine whether young women with functional hypothalamic amenorrhea (premenopausal HypoE) is associated with risk factors for pre-clinical cardiovascular disease (CVD).
- Conditions
- Estrogen Deficiency, Cardiovascular Disease (CVD), Functional Hypothalamic Amenorrhea, Endothelial Dysfunction
- Trial name
- NCT03018366
- Testing
- 17beta Estradiol, Progesterone
- Where
- United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Cedars-Sinai Medical Center
Amenorrhea, Dysmenorrhea
Reproductive Effects of Pesticide, PCB and Mercury Exposure in Laotian Immigrants
This project is examining the reproductive effects of exposure to certain compounds that are suspected to act on the endocrine system, e.g. they may act like or interfere with hormones such as estrogen.
- Conditions
- Amenorrhea, Dysmenorrhea, Oligomenorrhea, Anovulation
- Trial name
- NCT00011388
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- National Institute of Environmental Health Sciences (NIEHS)