Clinical trials: Amenorrhea
Anovulation
The Cycle Disturbances, OLigomenorrhea and Amenorrhea (COLA) Study & Biobank
Through the COLA Study and Biobank the investigators hope to enable further identification of phenotype, endocrine, ethnic, and metabolic characteristics associated with menstrual cycle disturbances; and: the identification of…
- Trial name
- COLA (NCT02309047)
- Where
- Netherlands
- Volunteers
- 5,000 people
- Sponsor
- UMC Utrecht
Weight Gain, Amenorrhea
Efficacy and Safety of Metformin in Preventing Patients With Risperidone From Weight Gain and Amenorrhea
Some previous studies has demonstrated that Metformin can improve the weight gain which caused by antipsychotics. An our study, which will be published, also found that Metformin can improve the amenorrhea for patients with…
- Trial name
- NCT01423487
- Testing
- Metformin, Starch tablets
- Where
- China
- Sponsor
- Central South University
Eating Disorders, Hypoestrogenemia
The Role of Estrogen in the Neurobiology of Eating Disorders
This is a randomized, double blind, placebo-controlled study of the effects of transdermal estradiol versus placebo on cognitive flexibility, reward processing, and eating disorder pathology in hypoestrogenemic female adolescents…
- Trial name
- NCT03740204
- Testing
- 17-β estradiol transdermal patches with cyclic progesterone
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Massachusetts General Hospital
Hypogonadism, Hypergonadism
Observation of Environment and Reproductive-Endocrine Effects
Background: Endocrine disorders occur when the glands that make hormones do not work properly. Hormones levels that are too high or too low can cause problems such as late or early puberty, irregular periods, and infertility.
- Conditions
- Hypogonadism, Hypergonadism, Precocious Puberty, Late Puberty
- Trial name
- NCT06280807
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- National Institute of Environmental Health Sciences (NIEHS)
FHA (Functional Hypothalamic Amenorrhea)
Romosozumab as an Adjunct to Physiologic Estrogen Replacement in Functional Hypothalamic Amenorrhea
The goal of this study is to determine whether romosozumab will improve bone density in girls and women with functional hypothalamic amenorrhea (cessation of the menstrual period due to intense exercise, stress, or an eating…
- Trial name
- NCT06533865
- Testing
- Romosozumab, Zoledronic acid
- Where
- 2 sites in United States
- Volunteers
- 114 people
- Sponsor
- Massachusetts General Hospital
Pregnancy During Breastfeeding, Lactational Amenorrhea Method
Emergency Contraception as a Back up of Lactational Amenorrhea Method(LAM)
Prolonged breast-feeding is an encouraged tradition in Egypt. Breastfeeding is associated with variable degrees of amenorrhea and infertility but there is a risk of resumption of fertility and therefore, of conception during…
- Trial name
- ECLAM (NCT01111929)
- Testing
- Counseling for LAM+ LNG-EC
- Volunteers
- 1,174 people
- Sponsor
- Assiut University
Amenorrhea
Effect of Intense Training on Ovarian Function and Bone Turnover
The investigators propose a prospective, longitudinal, department funded study protocol to evaluate whether changes in energy availability, during a period of highly intensified exercise training, will increase bone turnover…
- Trial name
- NCT02224976
- Testing
- Intensified Training
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- USDA, Western Human Nutrition Research Center
Polycystic Ovary Syndrome, PCOS
Insulin Differences Between African-American and Caucasian Female Adolescents With Polycystic Ovary Syndrome (PCOS)
The purpose of this research study is to see if there are differences between African-American and Caucasian girls with Polycystic Ovary Syndrome (PCOS) in how their bodies respond to a type of sugar, called glucose, the body's…
- Trial name
- NCT02052479
- Testing
- Frequently Sampled Intravenous Glucose Tolerance Test (FSIVGTT)
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Nationwide Children's Hospital
to Study the Estimate Difficulty of Insertion Mirena IUD With Use of Prostaglandins
Prostaglandins Use Before Mirena IUD Insertion in Prev CS Women During Lactational Amenorrhea
This is a prospective randomized controlled study to determine the effect of prostaglandin intake before Mirena IUD insertion It was conducted at the Department of Obstetrics \& Gynecology, Kasr El-Ainy Teaching Hospital, Faculty…
- Trial name
- NCT04646161
- Testing
- Misoprostol
- Where
- Egypt
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Cairo University
Endocrine Disease, Infertility
Hormonal Regulation of Puberty and Fertility
Background: The body produces gonadotropin-releasing hormone (GnRH) about every 2 hours. GnRH travels through the bloodstream to the pituitary gland, where it stimulates the gland to produce hormones called gonadotropins.
- Conditions
- Endocrine Disease, Infertility, Hypogonadism, Amenorrhea
- Trial name
- NCT01511588
- Where
- 2 sites in United States
- Volunteers
- 111 people
- Sponsor
- National Institute of Environmental Health Sciences (NIEHS)
Functional Hypothalamic Amenorrhea, FHA
A Study to Investigate Mibavademab in Adult Women With Functional Hypothalamic Amenorrhea
This study is researching an experimental drug called mibavademab (also called "study drug"). The study is focused on participants with a condition called Functional Hypothalamic Amenorrhea (FHA).
- Trial name
- KYRIAD (NCT07235917)
- Testing
- Mibavademab
- Where
- 11 sites in United States
- Volunteers
- 34 people
- Sponsor
- Regeneron Pharmaceuticals